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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

KLHL7 Gene

protein-coding GIFtS: 51
GCID: GC07P023145

kelch-like family member 7

(Previous name: kelch-like 7 (Drosophila) )

Explore 4 diseases affiliated with
KLHL7 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Kelch-Like Family Member 7¹ ²		Kelch-Like 6²
KLHL6¹ ²		Kelch-Like 7²
SBBI26¹ ²		Kelch-Like Protein 7²
RP42¹ ⁵		Kelch/BTB¹
Kelch-Like 7 (Drosophila)¹

External Ids:	HGNC: 15646¹	Entrez Gene: 55975²	Ensembl: ENSG00000122550⁷	OMIM: 611119⁵	UniProtKB: Q8IXQ5³

Export aliases for KLHL7 gene to outside databases

Previous GC identifers: GC00U991218 GC07P022888 GC07P022918 GC07P023111 GC07P023029

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KLHL7:

This gene encodes a BTB-Kelch-related protein. The encoded protein may be involved in protein degradation. Mutations in

this gene have been associated with retinitis pigmentosa 42. (provided by RefSeq, Feb 2010)

UniProtKB/Swiss-Prot: KLHL7_HUMAN, Q8IXQ5

Function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts

by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked

ubiquitination

Gene Wiki entry for KLHL7

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the KLHL7 gene promoter:
ER-alpha Pax-2 Pax-2a C/EBPalpha CREB SRY Pax-2b FOXO4 deltaCREB ATF6
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): KLHL7 promoter sequence

Search SABiosciences Chromatin IP Primers for KLHL7

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLHL7

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.3 Ensembl cytogenetic band: 7p15.3 HGNC cytogenetic band: 7p15.3

KLHL7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLHL7 gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07P023145: view genomic region (about GC identifiers)

Start:	23,145,353 bp from pter	End:	23,215,040 bp from pter
Size:	69,688 bases	Orientation:	plus strand

1 alternative location:

Chr7+,CRA_TCAG 23,197,216-23,266,913

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: KLHL7_HUMAN, Q8IXQ5 (See protein sequence)

Recommended Name: Kelch-like protein 7

Size: 586 amino acids; 65992 Da

Subunit: Homodimer. Component of the BCR(KLHL7) E3 ubiquitin ligase complex, at least composed of CUL3 and KLHL7 and

RBX1

Subcellular location: Nucleus

1 PDB 3D structure from and Proteopedia for KLHL7:

3II7 (3D)

Secondary accessions: A4D144 Q7Z765 Q96MV2 Q9BQF8 Q9UDQ9

Alternative splicing: 4 isoforms: Q8IXQ5-1 Q8IXQ5-2 Q8IXQ5-3 Q8IXQ5-4 (Variant in position: 18:K->R (in dbSNP:rs17147682))

Explore the universe of human proteins at neXtProt for KLHL7: NX_Q8IXQ5

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8IXQ5

KLHL7 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001026880.2 NP_001165899.1 NP_061334.4

ENSEMBL proteins:

ENSP00000430351 ENSP00000343273 ENSP00000323270 ENSP00000386263 ENSP00000386999

ENSP00000404181 ENSP00000322958 ENSP00000442366 ENSP00000446445 ENSP00000441136

ENSP00000442367

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	Uscn Proteins for KLHL7

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005730	NOT nucleolus	IDA	--
GO:0005737	cytoplasm	IDA	--
GO:0005886	plasma membrane	IDA	--
GO:0031463	Cul3-RING ubiquitin ligase complex	IDA	--

KLHL7 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

KLHL7 for domains About GeneDecksing

5/7 InterPro domains/families (see all 7):

IPR017096 Kelch-like_gigaxonin

IPR000210 BTB/POZ-like

IPR006652 Kelch_1

IPR011333 BTB/POZ_fold

IPR013069 BTB_POZ

Graphical View of Domain Structure for InterPro Entry Q8IXQ5

ProtoNet protein and cluster: Q8IXQ5

2 Blocks protein families:

IPB000210 BTB/POZ domain

IPB011705 BTB/Kelch-associated

UniProtKB/Swiss-Prot: KLHL7_HUMAN, Q8IXQ5

Similarity: Contains 1 BACK (BTB/Kelch associated) domain

Similarity: Contains 1 BTB (POZ) domain

Similarity: Contains 6 Kelch repeats

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: KLHL7_HUMAN, Q8IXQ5

Function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts

by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked

ubiquitination

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0042803	protein homodimerization activity	IDA	--

KLHL7 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for KLHL7

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		hsa-miR-1271 hsa-miR-3121-3p hsa-miR-96
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHL7

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

UniProtKB/Swiss-Prot: KLHL7_HUMAN, Q8IXQ5

Pathway: Protein modification; protein ubiquitination

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for KLHL7

STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

5/14 Interacting proteins for KLHL7 (Q8IXQ5³ ENSP00000343273⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 14)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
AXIN2	Q9Y2T1³	I2D: score=1
CUL3	ENSP00000264414⁴	STRING: ENSP00000264414
KLHL12	ENSP00000356230⁴	STRING: ENSP00000356230
KLHL13	ENSP00000262820⁴	STRING: ENSP00000262820
KLHL3	ENSP00000312397⁴	STRING: ENSP00000312397

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016567	protein ubiquitination	IEA	--

KLHL7 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for KLHL7
Search CenterWatch for drugs/clinical trials and news about KLHL7

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for KLHL7 gene (3 alternative transcripts):

NM_001031710.2 NM_001172428.1 NM_018846.4

Unigene Cluster for KLHL7:

Kelch-like 7 (Drosophila)

Hs.654817 [show with all ESTs]

Unigene Representative Sequence: NR_033328

18 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000479288 ENST00000521082 ENST00000339077(uc011jyv.2) ENST00000322275(uc003svp.3 uc003svq.3)

ENST00000459661 ENST00000491352 ENST00000409689(uc003svt.3) ENST00000410047

ENST00000479700 ENST00000477076 ENST00000414163 ENST00000469576 ENST00000469845

ENST00000322231(uc003svr.4 uc003svs.4 uc011jys.2 uc011jyt.2)

ENST00000545443 ENST00000545771(uc011jyu.2) ENST00000539124 ENST00000542558

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		3 QIAGEN miScript miRNA Assays for microRNAs that regulate KLHL7:
		hsa-miR-1271 hsa-miR-3121-3p hsa-miR-96
		SwitchGear 3'UTR luciferase reporter plasmid: KLHL7 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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Additional cDNA sequence:

AF111113.1 AK055473.1 AK056390.1 AK290479.1 AK296219.1 AK297369.1 AK297421.1 AK297595.1

AK299006.1 AK302995.1 AL136597.1 AL834193.1 AY028802.1 BC009555.1 BC039585.1 EF560731.1

NR_033328.1 NR_033329.1

12 DOTS entries:

DT.213612 DT.91660250 DT.92427999 DT.95289414 DT.100794817 DT.91669090 DT.91923178 DT.97824868

DT.92427992 DT.92428000 DT.40218618 DT.95241522

24/170 AceView cDNA sequences (see all 170):

BX100739 CF272535 AA478899 NM_018846 CB146713 BF000829 H99846 BP344448

CA945015 BC009555 AL834193 CA424920 AA928061 AI080154 Z38380 BE786124

AA431362 AK056390 AI631753 AI284488 BI768218 AA736498 AA432360 AU252407

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for KLHL7 (see all 8) About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3a	·	3b	^	4a	·	4b	·	4c	^	5	^	6	^	7	^	8a	·	8b	^	9	^	10	^	11a	·	11b	^	12a	·	12b	^	13a	·	13b	^	14a	·	14b
SP1:																							-																-		-
SP2:
SP3:							-
SP4:							-		-		-		-		-		-		-		-		-
SP5:							-		-		-

ECgene alternative splicing isoforms for KLHL7

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

KLHL7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAAGCTGTC

About this image

KLHL7 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

ES04(HES-4) (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See KLHL7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KLHL7

SOURCE GeneReport for Unigene cluster: Hs.654817

UniProtKB/Swiss-Prot: KLHL7_HUMAN, Q8IXQ5

Tissue specificity: Widely expressed, with highest levels in adult and fetal heart, CNS and adult testis

SABiosciences Expression via Pathway-Focused PCR Array including KLHL7:

Ubiquitin Ligases in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for KLHL7 gene from 4/18 species (see all 18) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	KLHL7¹	kelch-like 7 (Drosophila)	84.98(n) 98.12(a)		420612 NM_001012857.1 NP_001012875.1
lizard (Anolis carolinensis)	Reptilia	KLHL7⁶	--	97(a)	1 ↔ 1	6(30404218-30421880)
African clawed frog (Xenopus laevis)	Amphibia	Xl.7658²	Xenopus laevis transcribed sequence with strong similarity more	81.25(n)		BX843731.1
zebrafish (Danio rerio)	Actinopterygii	zgc63520²	hypothetical protein MGC63520	72.11(n)		393851 BC063745.1

ENSEMBL Gene Tree for KLHL7 (if available)
TreeFam Gene Tree for KLHL7 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for KLHL7 gene

KBTBD12² KLHL40² KBTBD7² KBTBD2² KBTBD8² KBTBD6² KLHL41²

18/26 SIMAP similar genes for KLHL7 using alignment to 7 protein entries: KLHL7_HUMAN (see all proteins) (see all similar genes):

ZBTB21 ZBTB16 KLHL32 ZBTB14 BTBD3 KBTBD3

KBTBD4 KBTBD8 MYNN ZBTB38 ZBTB49 KLHL3

KLHL20 KLHL17 KLHL28 KEAP1 KLHL5 KLHL29

KLHL7 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs56400441^1,2	C	--	23143564(+)	`CATGTG/AGTAGG`	5	--	us2k¹ int¹		8		WA NA CSA EA	367
rs183040160^1,2		--	23143606(+)	`TAACAC/GAAGTT`	5	--	us2k¹ int¹		0	--	--	--	--
rs188421801^1,2		--	23143656(+)	`TGTTTC/GACTTT`	5	--	us2k¹ int¹		0	--	--	--	--
rs192135375^1,2		--	23143720(+)	`TCTTTC/GAGCTC`	5	--	us2k¹ int¹		0	--	--	--	--
rs183123698^1,2		--	23143775(+)	`CAATAC/TGTAAA`	5	--	us2k¹ int¹		0	--	--	--	--
rs149768295^1,2		--	23143842(+)	`ATTACA/TGGACA`	5	--	us2k¹ int¹		0	--	--	--	--
rs13438179^1,2	C,F,H	--	23143851(+)	`CAGCAT/CTCTTT`	5	--	int¹ us2k¹		23		NS EA NA WA CSA	2264
rs145725275^1,2		--	23143997(+)	`GGTCAC/TTTAAT`	6	--	us2k¹ int¹		0	--	--	--	--
rs187821615^1,2		--	23144141(+)	`AAAGAC/TAAAGA`	6	--	us2k¹ int¹		0	--	--	--	--
rs10488077^1,2	C,F,H	--	23144182(+)	`TAAAAA/TTTGAG`	6	--	us2k¹ int¹		19		NS EA NA WA	986

HapMap Linkage Disequilibrium report for KLHL7 (23145353 - 23215040 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for KLHL7
5 CNVs: 69824 52195 52194 32877 69825
1 Indel: 52196
Human Gene Mutation Database (HGMD): KLHL7

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KLHL7

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

KLHL7 for disorders           About GeneDecksing

OMIM gene information: 611119
OMIM disorders: 612943
UniProtKB/Swiss-Prot: KLHL7_HUMAN, Q8IXQ5

Defects in KLHL7 are the cause of retinitis pigmentosa type 42 (RP42) [MIM:612943]. A retinal dystrophy

belonging to the group of pigmentary retinopathies. RP is characterized by retinal pigment deposits visible on fundus

examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients

typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose

their far peripheral visual field and eventually central vision as well

4 diseases for KLHL7: About MalaCards

retinitis pigmentosa retinitis pigmentary retinopathy blindness

1 disease from the University of Copenhagen DISEASES database for KLHL7:

Retinitis pigmentosa

Export disorders for KLHL7 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for KLHL7 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with KLHL7)

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Mutations in a BTB-Kelch protein, KLHL7, cause autoso mal-dominant retinitis pigmentosa. (PubMed id 19520207)^{1, 2, 3} Friedman J.S....Swaroop A. (2009)
Phenotypic characterization of 3 families with autoso mal dominant retinitis pigmentosa due to mutations in KLHL7. (PubMed id 22084217)^{1, 2} Wen Y....Hughbanks-Wheaton D.K. (2011)
Ubiquitin ligase activity of Cul3-KLHL7 protein is at tenuated by autosomal dominant retinitis pigmentosa causative mutation. (PubMed id 21828050)^{1, 2} Kigoshi Y....Chiba T. (2011)
Phenotype associated with mutation in the recently id entified autosomal dominant retinitis pigmentosa KLHL7 gene. (PubMed id 20547956)^{1, 2} Hugosson T....AndrAcasson S. (2010)
Detection of autoantibodies to the BTB-kelch protein KLHL7 in cancer sera. (PubMed id 16918702)^{1, 2} Bredholt G.... Vedeler C.A. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{1, 2} Hillier L.W.... Wilson R.K. (2003)
Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)^{1, 2} Wiemann S.... Poustka A. (2001)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 55975	HGNC: 15646	AceView: KLHL7	Ensembl:ENSG00000122550	euGenes: HUgn55975
ECgene: KLHL7	H-InvDB: KLHL7

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for KLHL7	Pharmacogenomics, SNPs, Pathways

Intellectual Property for KLHL7 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for KLHL7 gene:
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KLHL7 Gene

kelch-like family member 7

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KLHL7 Gene

kelch-like family member 7

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