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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KLHL5 Gene

protein-coding   GIFtS: 52
GCID: GC04P038961

Kelch-Like Family Member 5

(Previous names: kelch (Drosophila)-like 5, kelch-like 5 (Drosophila))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Kelch-Like Family Member 51 2
Kelch (Drosophila)-Like 51
Kelch-Like 5 (Drosophila)1
Kelch-Like Protein 52
Lymphocyte Activation-Associated Protein2

External Ids:    HGNC: 63561   Entrez Gene: 510882   Ensembl: ENSG000001097907   OMIM: 6080645   UniProtKB: Q96PQ73   

Export aliases for KLHL5 gene to outside databases

Previous GC identifers: GC04M038768 GC04M039139 GC04P038898 GC04P038886 GC04P038723 GC04P038371


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for KLHL5 Gene: 
KLHL5 (kelch-like family member 5) is a protein-coding gene. Diseases associated with KLHL5 include thyroiditis, and prostatitis. GO annotations related to this gene include actin binding and molecular_function. An important paralog of this gene is KLHL17.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016297.16  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KLHL5 gene promoter:
         IRF-1   HNF-3beta   AREB6   HEN1   POU2F1   POU2F1a   POU2F1b   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKLHL5 promoter sequence
   Search SABiosciences Chromatin IP Primers for KLHL5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLHL5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p14   Ensembl cytogenetic band:  4p14   HGNC cytogenetic band: 4p15.1

KLHL5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLHL5 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P038961:  view genomic region     (about GC identifiers)

Start:
39,046,451 bp from pter      End:
39,128,477 bp from pter
Size:
82,027 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KLHL5_HUMAN, Q96PQ7 (See protein sequence)
Recommended Name: Kelch-like protein 5  
Size: 755 amino acids; 84457 Da
Subcellular location: Cytoplasm, cytoskeleton
Sequence caution: Sequence=AAD32565.1; Type=Erroneous initiation; Sequence=AAL08584.1; Type=Erroneous termination;
Positions=735; Note=Translated as Trp; Sequence=BAA91845.1; Type=Erroneous initiation; Sequence=BAA91933.1;
Type=Erroneous initiation; Sequence=BAA92121.1; Type=Erroneous initiation;
Secondary accessions: A8K170 B7WP68 E9PCF4 F8WAE7 G3XA92 Q6Y881 Q86XW0 Q9NUK3 Q9NV27 Q9NVA9
Q9Y2X2
Alternative splicing: 6 isoforms:  Q96PQ7-1   Q96PQ7-2   Q96PQ7-3   Q96PQ7-4   Q96PQ7-5   Q96PQ7-6   (Ubiquitous expression, differentially expressed in kidney and pancreas relatively to isoform 1)

Explore the universe of human proteins at neXtProt for KLHL5: NX_Q96PQ7

Explore proteomics data for KLHL5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96PQ7

  • KLHL5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KLHL5 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001007076.1  NP_001165125.1  NP_057074.3  NP_950240.2  

    ENSEMBL proteins: 
     ENSP00000261425   ENSP00000423080   ENSP00000423897   ENSP00000371355   ENSP00000261426  
     ENSP00000426949   ENSP00000425512   ENSP00000352716  

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    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm NAS14672410
    GO:0005856cytoskeleton IEA--

    KLHL5 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    BTBD: BTB/POZ domain containing
    KLHL: Kelch-like

    5/6 InterPro protein domains (see all 6):
     IPR006652 Kelch_1
     IPR011333 BTB/POZ_fold
     IPR015916 Gal_Oxidase_b-propeller
     IPR013069 BTB_POZ
     IPR011705 BACK

    Graphical View of Domain Structure for InterPro Entry Q96PQ7

    ProtoNet protein and cluster: Q96PQ7

    2 Blocks protein domains:
    IPB000210 BTB/POZ domain
    IPB011705 BTB/Kelch-associated


    UniProtKB/Swiss-Prot: KLHL5_HUMAN, Q96PQ7
    Similarity: Contains 1 BTB (POZ) domain
    Similarity: Contains 6 Kelch repeats


    KLHL5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0003779actin binding IEA--
    GO:0005515protein binding ----
         
    KLHL5 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for KLHL5 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KLHL5 
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    hsa-miR-411* hsa-miR-140-5p hsa-miR-379* hsa-miR-507 hsa-miR-105 hsa-miR-374a* hsa-miR-378 hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidKLHL5 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KLHL5

    5/10 Interacting proteins for KLHL5 (Q96PQ72, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMN1Q166372, 3MINT-8271256 I2D: score=2 
    SMN2Q166372, 3MINT-8271256 I2D: score=2 
    GABARAPL2P605202, 3MINT-8255580 I2D: score=2 
    MAP1LC3BQ9GZQ82, 3MINT-8259654 I2D: score=2 
    TK1P041832, 3MINT-8273664 I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    KLHL5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KLHL5

    Search CenterWatch for drugs/clinical trials and news about KLHL5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KLHL5 gene (4 alternative transcripts): 
    NM_001007075.2  NM_001171654.1  NM_015990.4  NM_199039.3  

    Unigene Cluster for KLHL5:

    Kelch-like family member 5
    Hs.272251  [show with all ESTs]
    Unigene Representative Sequence: NM_015990
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000261425(uc003gtp.3 uc003gtq.3 uc003gts.3) ENST00000508137
    ENST00000504108 ENST00000381930(uc003gtr.2) ENST00000261426(uc003gtt.3)
    ENST00000514399 ENST00000515612 ENST00000359687
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KLHL5
    8/51 QIAGEN miScript miRNA Assays for microRNAs that regulate KLHL5 (see all 51):
    hsa-miR-411* hsa-miR-140-5p hsa-miR-379* hsa-miR-507 hsa-miR-105 hsa-miR-374a* hsa-miR-378 hsa-miR-23a
    SwitchGear 3'UTR luciferase reporter plasmidKLHL5 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KLHL5

    Additional mRNA sequence: 

    AB208820.1 AK001698.1 AK002174.1 AK002175.1 AK289785.1 AL049385.1 AY172948.1 BC010867.1 
    BC048262.1 BC053860.1 BC058884.1 BC081562.1 

    14 DOTS entries:

    DT.101982669  DT.207244  DT.444861  DT.100794880  DT.121251589  DT.40198527  DT.91986967  DT.40108980 
    DT.121273008  DT.91908882  DT.121233080  DT.121272999  DT.207631  DT.95374179 

    24/259 AceView cDNA sequences (see all 259):

    BQ005921 BM129645 AA708594 BX110533 CR604008 BM552280 AU139185 BE501881 
    AI654168 AL049385 BQ009010 BM806847 CK818853 AI732261 AA482594 BM127138 
    BQ010589 AA489161 AA732620 BC048262 R70258 AA748733 AA969586 AW302174 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for KLHL5 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b
    SP1:                                                                                                              -                     
    SP2:                    -     -     -     -                                                                       -                     
    SP3:                                                                                                                                    
    SP4:                                                                                                                                    
    SP5:                                                                                                        -     -     -               


    ECgene alternative splicing isoforms for KLHL5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KLHL5 expression in normal human tissues (normalized intensities)      KLHL5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGTTTTGCA
    KLHL5 Expression
    About this image


    KLHL5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Peripheral Nervous System (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Limb (Muscoskeletal System)
             Autopod
     
     Spinal Cord (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Eye (Sensory Organs)
             Type1 Off Cone Bipolar Cells Inner Nuclear Layer

    See KLHL5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KLHL5

    SOURCE GeneReport for Unigene cluster: Hs.272251

    UniProtKB/Swiss-Prot: KLHL5_HUMAN, Q96PQ7
    Tissue specificity: Expressed in adrenal gland, ovary and thyroid gland and less abundantly in lymph node,
    prostate, spinal chord, testis and trachea

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for KLHL5 gene from 5/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Klhl51 , 5 kelch-like 5 (Drosophila)1, 5 87.57(n)1
    97.32(a)1
      5 (33.58 cM)5
    717781  NM_175174.41  NP_780383.21 
     651075685 
    chicken
    (Gallus gallus)
    Aves KLHL51 kelch-like 5 (Drosophila) 83.64(n)
    92.64(a)
      425121  XM_422912.3  XP_422912.2 
    lizard
    (Anolis carolinensis)
    Reptilia KLHL56
    Uncharacterized protein
    88(a)
    1 ↔ 1
    5(73193557-73225956)
    zebrafish
    (Danio rerio)
    Actinopterygii klhl51 kelch-like 5 (Drosophila) 66.76(n)
    76.02(a)
      560697  NM_001170942.1  NP_001164413.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG177541 , 3 CG177541 60(a)
    (best of 3)3
    53.79(n)1
    57.12(a)1
      8D103
    318731  NM_132321.31  NP_572549.21 


    ENSEMBL Gene Tree for KLHL5 (if available)
    TreeFam Gene Tree for KLHL5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KLHL5 gene
    KLHL172  KLHL182  KLHL202  KLHL122  KEAP12  KLHL282  KLHL42  KLHL32  
    IPP2  KLHL82  KLHL102  KLHL12  KLHL22  
    18/32 SIMAP similar genes for KLHL5 using alignment to 7 protein entries:     KLHL5_HUMAN (see all proteins) (see all similar genes):
    DKFZp761P1717    KLHL1    KLHL4    KLHL20    KLHL17    KLHL3
    KLHL28    KLHL8    KLHL2    KBTBD3    DKFZp781C1855    KLHL18
    KLHL12    DKFZp686H07112    DKFZp686P15123    KLHL32    KLHL10    KEAP1

    KLHL5 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for KLHL5
    PGOHUM00000257002


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1736 SNPs in KLHL5 are shown (see all 1736)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1149303541,2
    C--38935968(+) TCTTTA/CTTATT 2 -- us2k10--------
    rs1931708621,2
    --38936161(+) GACGGA/GGTTTC 2 -- us2k10--------
    rs27119831,2
    C,F,H--38936389(+) TCCAAA/GACTGA 2 -- us2k1 tfbs329Minor allele frequency- G:0.19NS EA NA WA CSA 2582
    rs1835777831,2
    --38936566(+) TTAAAA/GACAAA 2 -- us2k10--------
    rs1163149091,2
    C,F--38936609(+) GTGTCA/GTGGCA 2 -- us2k11Minor allele frequency- G:0.02WA 118
    rs1424485021,2
    --38936727(+) TGTAAA/CAATCT 2 -- us2k10--------
    rs1479475071,2
    --38936914(+) CTTCTC/GGACCA 2 -- us2k10--------
    rs14303651,2
    C,F,A,H--38937046(-) GTTTGC/TTACTC 2 -- us2k120Minor allele frequency- T:0.26NS EA NA WA CSA 2230
    rs1417744691,2
    --38937285(+) TCTCAC/TGACCT 2 -- us2k10--------
    rs131284821,2
    C,F--38937337(+) AACCTA/GCTTTT 2 -- us2k15Minor allele frequency- G:0.13NA WA 244

    HapMap Linkage Disequilibrium report for KLHL5 (39046451 - 39128477 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for KLHL5:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2727455CNV Deletion23290073
    esv272117CNV Insertion20981092
    esv274607CNV Insertion20981092
    esv28537CNV Loss19812545
    esv28236CNV Gain19812545
    nsv878940CNV Gain21882294
    nsv822540CNV Gain20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608064    OMIM disorders: --

    2 diseases for KLHL5:    About MalaCards
    thyroiditis    prostatitis


    KLHL5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): KLHL5
    Human Genome Epidemiology (HuGE) Navigator: KLHL5 (1 document)

    Export disorders for KLHL5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KLHL5 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with KLHL5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of a novel splicing variant of KLHL5, a member of the kelch protein family. (PubMed id 14672410)1, 2, 3, 9 Xu J....Mao Y. (2003)
    2. Cloning and characterization of KLHL5, a novel human gene encoding a kelch-related protein with a BTB domain. (PubMed id 11590829)1, 2, 3 Wang S.... Mao Y. (2001)
    3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    7. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    8. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)
    9. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    10. Single-nucleotide polymorphisms, acute rejection, and severity of tubulitis in kidney transplantation, accounting for center-to-center variation. (PubMed id 21085059)4 Israni A....Oetting W.S. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51088 HGNC: 6356 AceView: KLHL5 Ensembl:ENSG00000109790 euGenes: HUgn51088
    ECgene: KLHL5 H-InvDB: KLHL5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KLHL5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KLHL5 gene:
    Search GeneIP for patents involving KLHL5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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