KLHL4 Gene
protein-coding GIFtS : 49
GCID: GC0X P086772
kelch-like family member 4 (Previous names: kelch (Drosophila)-like 4, kelch-like 4 (Drosophila) )
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Aliasesfor KLHL4 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Kelch-Like Family Member 4 1 2 Kelch (Drosophila)-Like 41 DKELCHL1 2 Kelch-Like 4 (Drosophila)1 KHL41 2 Kelch-Like Protein 42 KIAA16871 3
Export aliases for KLHL4 gene to outside databases Previous GC identifers: GC0XP082152 GC0XP083849 GC0XP084808 GC0XP085544 GC0XP086578 GC0XP080353
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Summariesfor KLHL4 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for KLHL4 : This gene encodes a member of the kelch family of proteins, which are characterized by kelch repeat motifs and a POZ/BTB protein-binding domain. It is thought that kelch repeats are actin binding domains. However, the specific function of this protein has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. (provided by RefSeq, Jul 2008)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Viewsfor KLHL4 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000023.10 NC_018934.1 NT_011651.17 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the KLHL4 gene promoter: Nkx3-1 HOXA9 HOXA9B Nkx3-1 v4 Nkx3-1 v1 AREB6 Nkx3-1 v2 Nkx3-1 v3 Meis-1a Meis-1 Other transcription factors Search SABiosciences Chromatin IP Primers for KLHL4 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLHL4
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: Xq21.3 Ensembl cytogenetic band: Xq21.31 HGNC cytogenetic band: Xq21.3 KLHL4 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome X GeneLoc Exon Structure
GeneLoc location for GC0XP086772: view genomic region
(about GC identifiers )
Start:
86,772,715 bp from pter
End:
86,925,050 bp from pter
Size:
152,336 bases
Orientation:
plus strand
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Proteinsfor KLHL4 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: KLHL4_HUMAN, Q9C0H6 (See
protein sequence )Recommended Name: Kelch-like protein 4 Size : 718 amino acids; 80245 Da
Subcellular location : Cytoplasm, cytoskeleton
Sequence caution : Sequence=BAB14199.1; Type=Erroneous initiation; Sequence=BAB21778.1; Type=Erroneous initiation;
Secondary accessions : B2RTW2 Q9Y3J5Alternative splicing : 2 isoforms : Q9C0H6-1 Q9C0H6-2 Explore the universe of human proteins at neXtProt for KLHL4: NX_Q9C0H6 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9C0H6 KLHL4 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins (2 alternative transcripts):
NP_061990.2 NP_476503.1 ENSEMBL proteins: ENSP00000362211 ENSP00000362206 Human Recombinant Protein Products for KLHL4: Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view) : About this table
KLHL4 for ontologies About GeneDecksing KLHL4 Antibody Products: Assay Products for KLHL4:
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Protein
Domains / Familiesfor KLHL4 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
KLHL4 for domains About GeneDecksing 5/6 InterPro domains/families (see all 6 ):
Graphical View of Domain Structure for InterPro Entry Q9C0H6 ProtoNet protein and cluster: Q9C0H6
2 Blocks protein families : IPB000210 BTB/POZ domain IPB011705 BTB/Kelch-associated UniProtKB/Swiss-Prot: KLHL4_HUMAN, Q9C0H6 Similarity : Contains 1 BTB (POZ) domainSimilarity : Contains 6 Kelch repeats
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Functionfor KLHL4 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0003674 molecular_function
ND -- GO:0003779 actin binding
IEA --
KLHL4 for ontologies About GeneDecksing Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for KLHL4 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for KLHL4 (see all 2 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): KLHL4 (NM_019117 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KLHL4 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat KLHL4
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHL4
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Pathways & Interactionsfor KLHL4 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KLHL4 STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)2 Interacting proteins for KLHL4 (ENSP00000362206 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 1 biological process term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0008150 biological_process
ND --
KLHL4 for ontologies About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Drugs & Compoundsfor KLHL4 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for KLHL4 Search CenterWatch for drugs/clinical trials and news about KLHL4
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Transcriptsfor KLHL4 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for KLHL4 gene (2 alternative transcripts): NM_019117.4 NM_057162.2 Unigene Cluster for KLHL4:
Kelch-like 4 (Drosophila) Hs.49075 [show with all ESTs ] Unigene Representative Sequence: NM_019117 2 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000373119 (uc004efa.2 uc004efb.2 ) ENST00000373114 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for KLHL4 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for KLHL4 (see all 2 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): KLHL4 (NM_019117 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KLHL4 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat KLHL4
Additional cDNA sequence: AB051474.1 AF284765.1 AF284766.1 AK022715.1 AK023057.1 AK056457.1 AL831868.1 AL832514.1 BC140839.1 BC140840.1 BC142652.1 BC146677.1 BC161675.1
2 DOTS entries : DT.40113204 DT.95137528
24/36 AceView cDNA sequences (see all 36 ):
AI917374 BM718564 AU117238 AI679432 AU125721 NM_019117 AI675789 AI679942 AF284765 AL831868 AB051474 AA247484 AK023057 N64817 AK022715 AL832514 BX281120 AF284766 BU743007 AI743832 CB108922 AK056457 NM_057162 AU130089 GeneLoc Exon Structure
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Expression for KLHL4 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section KLHL4 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: CTTTTCTGTTAbout this image KLHL4 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
See KLHL4 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for KLHL4 SOURCE GeneReport for Unigene cluster: Hs.49075 UniProtKB/Swiss-Prot: KLHL4_HUMAN, Q9C0H6 Tissue specificity : Expressed in adult fibroblasts and in a range of fetal tissues including tongue, palate, andmandible SABiosciences Custom PCR Arrays for KLHL4 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for KLHL4Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat KLHL4 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat KLHL4 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat KLHL4 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHL4
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Orthologsfor KLHL4 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for KLHL4 gene from 5/21 species (see all 21 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
KLHL41
kelch-like 4 (Drosophila)
77.44(n) 83.29(a)
 
422265 XM_420250.3 XP_420250.2
lizard (Anolis carolinensis)
Reptilia
KLHL46
--
79(a)
1 ↔ 1
GL343409.1(146216-184977)
zebrafish (Danio rerio)
Actinopterygii
CABZ01080142.16 zgc:1622986 (see all 3 )
zgc:162298(see all 3 )
75(a) 74(a) (see all 3 )
1 ↔ many1 ↔ many(see all 3 )
Zv9_NA577(5907-10498) 14(27806002-27852531)
fruit fly (Drosophila melanogaster)
Insecta
CG177543
--
57(a) (best of 4)
 
8D10 --
worm (Caenorhabditis elegans)
Secernentea
T27E9.4b3
ring canal protein like
32(a) (best of 3)
 
III(13537863-13542591) --
ENSEMBL Gene Tree for KLHL4 (if available)TreeFam Gene Tree for KLHL4 (if available)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Paralogsfor KLHL4 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for KLHL4 gene KLHL17 2 KLHL18 2 KLHL20 2 KLHL5 2 KLHL12 2 KEAP1 2 KLHL28 2 IPP 2 KLHL3 2 KLHL8 2 KLHL10 2 KLHL1 2 KLHL2 2 18/21 SIMAP similar genes for KLHL4 using alignment to 2 protein entries: KLHL4_HUMAN (see all proteins )
(see all similar genes ):DKFZp761P1717 KLHL5 KLHL1 KLHL20 KLHL17 KLHL12 KLHL3 KLHL28 DKFZp686H07112 KLHL18 DKFZp686P15123 KLHL8 KLHL2 KBTBD3 KLHL10 IPP KEAP1 KLHL9
KLHL4 for paralogs About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Variantsfor KLHL4 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr X pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for KLHL4 (86772715 - 86925050 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for KLHL4: -- Locus Specific Mutation Databases (LSDB): KLHL4
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing KLHL4
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Disorders
/ Diseasesfor KLHL4 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
KLHL4 for disorders About GeneDecksing
OMIM gene information: 300348
OMIM disorders : --3 diseases for KLHL4 : About MalaCards mullerian aplasia cleft palate with ankyloglossia cleft palate 1 disease from the University of Copenhagen DISEASES database for KLHL4 :Cleft palate Export disorders for KLHL4 gene to outside databases
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Publicationsfor KLHL4 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for KLHL4 gene, integrated from 9 sources (see all 14 ): (articles sorted by number of sources associating them with KLHL4) Utopia : connect your pdf to the dynamic world of online information
Identification and characterization of KLHL4, a novel human homologue of the Drosophila Kelch gene that maps within the X-linked cleft palate and ankyloglossia (CPX) critical region. (PubMed id 11401425) 1 , 2 , 3 Braybrook C.... Stanier P. (2001) The DNA sequence of the human X chromosome. (PubMed id 15772651) 1 , 2 Ross M.T.... Bentley D.R. (2005) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970) 1 , 2 Nagase T.... Ohara O. (2000) Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461) 1 Bennett E.J....Harper J.W. (2010) Genomic imbalances associated with mullerian aplasia. (PubMed id 18039948) 1 Cheroki C....Rosenberg C. (2008) A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648) 2 Dephoure N.... Gygi S.P. (2008) Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348) 1 Barbe L....Andersson-Svahn H. (2008) The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005) 2 Bechtel S.... Schupp I. (2007) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 Kimura K.... Sugano S. (2006)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
External Searches for KLHL4 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genome Databases showing KLHL4 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Other Databases showing KLHL4 gene
(According to HUGE )
About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Specialized Databases showing KLHL4 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for KLHL4 Pharmacogenomics, SNPs, Pathways
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
About This Section Patent Information for KLHL4 gene: Search GeneIP for patents involving KLHL4 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Productsfor KLHL4 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for KLHL4 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for KLHL4 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for KLHL4 OriGene Protein Over-expression Lysate for KLHL4 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for KLHL4 OriGene 3'-UTR Clone for KLHL4 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for KLHL4 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for KLHL4 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for KLHL4 OriGene Custom Protein Services for KLHL4 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KLHL4 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing KLHL4 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLHL4 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat KLHL4 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat KLHL4 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat KLHL4
Search Tocris compounds for KLHL4
KLHL4 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHL4
Search ThermoFisher Antibodies for KLHL4
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat KLHL4
Jump to Section...
Aliases for KLHL4
Databases for KLHL4
Disorders / Diseases for KLHL4
Domains / Families for KLHL4
Drugs / Compounds for KLHL4
Expression for KLHL4
Function for KLHL4
Genomic Views for KLHL4
Intellectual Property for KLHL4
Orthologs for KLHL4
Paralogs for KLHL4
Pathways / Interactions for KLHL4
Products for KLHL4
Proteins for KLHL4
Publications for KLHL4
Search Box for KLHL4
Summaries for KLHL4
Transcripts for KLHL4
Variants for KLHL4
TOP
BOTTOM