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Aliases for KLHL32 Gene

Aliases for KLHL32 Gene

  • Kelch-Like Family Member 32 2 3
  • KIAA1900 2 3 4
  • BTB And Kelch Domain Containing 5 2 3
  • BKLHD5 3 4
  • BTB And Kelch Domain-Containing Protein 5 4
  • Kelch-Like 32 (Drosophila) 2
  • Kelch-Like Protein 32 3
  • UG0030H05 3
  • DJ21F7.1 3

External Ids for KLHL32 Gene

Previous HGNC Symbols for KLHL32 Gene

  • BKLHD5
  • KIAA1900

Previous GeneCards Identifiers for KLHL32 Gene

  • GC06P097480
  • GC06P097372
  • GC06P094806

Summaries for KLHL32 Gene

GeneCards Summary for KLHL32 Gene

KLHL32 (Kelch-Like Family Member 32) is a Protein Coding gene. An important paralog of this gene is KLHL36.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KLHL32 Gene

Genomics for KLHL32 Gene

Regulatory Elements for KLHL32 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for KLHL32 Gene

96,924,620 bp from pter
97,140,754 bp from pter
216,135 bases
Plus strand

Genomic View for KLHL32 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KLHL32 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KLHL32 Gene

Proteins for KLHL32 Gene

  • Protein details for KLHL32 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Kelch-like protein 32
    Protein Accession:
    Secondary Accessions:
    • B7Z346
    • B7Z4E2
    • E1P528
    • Q5THT0
    • Q96PY7

    Protein attributes for KLHL32 Gene

    620 amino acids
    Molecular mass:
    70362 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for KLHL32 Gene


neXtProt entry for KLHL32 Gene

Proteomics data for KLHL32 Gene at MOPED

Post-translational modifications for KLHL32 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for KLHL32 Gene

Domains for KLHL32 Gene

Gene Families for KLHL32 Gene

  • BTBD :BTB/POZ domain containing
  • KLHL :Kelch-like

Graphical View of Domain Structure for InterPro Entry



  • Q96NJ5
  • Contains 1 BTB (POZ) domain.
  • Contains 6 Kelch repeats.
genes like me logo Genes that share domains with KLHL32: view

Function for KLHL32 Gene

Gene Ontology (GO) - Molecular Function for KLHL32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with KLHL32: view

Phenotypes for KLHL32 Gene

genes like me logo Genes that share phenotypes with KLHL32: view

Animal Model Products

miRNA for KLHL32 Gene

miRTarBase miRNAs that target KLHL32

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for KLHL32 Gene

Localization for KLHL32 Gene

Subcellular locations from

Jensen Localization Image for KLHL32 Gene COMPARTMENTS Subcellular localization image for KLHL32 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KLHL32 Gene

Pathways for KLHL32 Gene

SuperPathways for KLHL32 Gene

No Data Available

Interacting Proteins for KLHL32 Gene

Gene Ontology (GO) - Biological Process for KLHL32 Gene


No data available for Pathways by source for KLHL32 Gene

Transcripts for KLHL32 Gene

Unigene Clusters for KLHL32 Gene

Kelch-like family member 32:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KLHL32

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KLHL32 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d ^ 10 ^ 11 ^ 12 ^ 13a · 13b
SP1: - - -
SP2: - - - - -
SP3: - - - - - - -
SP4: - -
SP6: -

Relevant External Links for KLHL32 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for KLHL32 Gene

mRNA expression in normal human tissues for KLHL32 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for KLHL32 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (6.5), Brain - Hippocampus (5.3), Brain - Substantia nigra (5.1), Brain - Hypothalamus (4.2), and Brain - Amygdala (4.1).

SOURCE GeneReport for Unigene cluster for KLHL32 Gene Hs.45056

genes like me logo Genes that share expressions with KLHL32: view

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for KLHL32 Gene

Orthologs for KLHL32 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KLHL32 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia KLHL32 35
  • 92.8 (n)
  • 98.23 (a)
KLHL32 36
  • 96 (a)
(Canis familiaris)
Mammalia KLHL32 35
  • 93.49 (n)
  • 99.03 (a)
KLHL32 36
  • 99 (a)
(Mus musculus)
Mammalia Klhl32 35
  • 91.34 (n)
  • 98.06 (a)
Klhl32 16
Klhl32 36
  • 98 (a)
(Pan troglodytes)
Mammalia KLHL32 35
  • 99.52 (n)
  • 99.68 (a)
KLHL32 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Klhl32 35
  • 91.61 (n)
  • 98.23 (a)
(Monodelphis domestica)
Mammalia KLHL32 36
  • 97 (a)
(Gallus gallus)
Aves KLHL32 35
  • 82.9 (n)
  • 94.19 (a)
KLHL32 36
  • 94 (a)
(Anolis carolinensis)
Reptilia KLHL32 36
  • 91 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.14602 35
(Danio rerio)
Actinopterygii klhl32 35
  • 72.31 (n)
  • 80 (a)
klhl32 36
  • 80 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 28 (a)
-- 36
  • 28 (a)
CSA.449 36
  • 29 (a)
Species with no ortholog for KLHL32:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KLHL32 Gene

Gene Tree for KLHL32 (if available)
Gene Tree for KLHL32 (if available)

Paralogs for KLHL32 Gene

genes like me logo Genes that share paralogs with KLHL32: view

Variants for KLHL32 Gene

Sequence variations from dbSNP and Humsavar for KLHL32 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs16719 -- 97,140,233(-) CTGAG(-/AG)TTACT utr-variant-3-prime, nc-transcript-variant
rs25637 -- 97,115,992(-) AGAAG(-/AACA)AACAG intron-variant
rs734667 -- 96,961,625(+) TACCT(C/G)TCTGA intron-variant
rs734836 -- 97,103,277(+) GGTGC(A/G/T)ATCTC intron-variant
rs736450 -- 97,027,878(+) GACTC(A/T)AGAGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KLHL32 Gene

Variant ID Type Subtype PubMed ID
nsv5402 CNV Insertion 18451855
esv1215963 CNV Insertion 17803354
nsv436524 CNV Deletion 17901297
esv2656950 CNV Deletion 23128226
esv27575 CNV Loss 19812545
nsv524695 CNV Loss 19592680
esv2370829 CNV Deletion 18987734
esv2732463 CNV Deletion 23290073
esv2661411 CNV Deletion 23128226
esv2604268 CNV Deletion 19546169
esv2396648 CNV Deletion 18987734
esv8405 CNV Loss 19470904
esv2732464 CNV Deletion 23290073
esv2676410 CNV Deletion 23128226
nsv886426 CNV Gain 21882294

Relevant External Links for KLHL32 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KLHL32 Gene

Disorders for KLHL32 Gene

(1) University of Copenhagen DISEASES for KLHL32 Gene

genes like me logo Genes that share disorders with KLHL32: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships , Genatlas and External Links for KLHL32 Gene

Publications for KLHL32 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PMID: 11572484) Nagase T. … Ohara O. (DNA Res. 2001) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for KLHL32 Gene

Sources for KLHL32 Gene

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