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KLHL28 Gene

protein-coding   GIFtS: 44
GCID: GC14M045393

Kelch-Like Family Member 28

(Previous names: BTB (POZ) domain containing 5, kelch-like 28 (Drosophila))
(Previous symbol: BTBD5)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Kelch-Like Family Member 281 2     Kelch-Like 28 (Drosophila)1
BTBD51 2 3     Kelch-Like 282
BTB (POZ) Domain Containing 51 2     Kelch-Like Protein 282
BTB/POZ Domain-Containing Protein 52 3     

External Ids:    HGNC: 197411   Entrez Gene: 548132   Ensembl: ENSG000001794547   UniProtKB: Q9NXS33   
ORGUL members:         

Export aliases for KLHL28 gene to outside databases

Previous GC identifers: GC14M044468 GC14M025504


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KLHL28 Gene:
KLHL28 (kelch-like family member 28) is a protein-coding gene. An important paralog of this gene is KLHL17.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NT_026437.13  NC_018925.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KLHL28 gene promoter:
         Nkx3-1   E2F-3a   E2F-4   E2F-5   Nkx3-1 v4   Nkx3-1 v1   E2F-2   Nkx3-1 v2   E2F-1   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKLHL28 promoter sequence
   Search Chromatin IP Primers for KLHL28

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KLHL28


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q21.2   Ensembl cytogenetic band:  14q21.2   HGNC cytogenetic band: 14q21.1

KLHL28 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLHL28 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M045393:  view genomic region     (about GC identifiers)

Start:
45,393,522 bp from pter      End:
45,511,525 bp from pter
Size:
118,004 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: KLH28_HUMAN, Q9NXS3 (See protein sequence)
Recommended Name: Kelch-like protein 28  
Size: 571 amino acids; 64192 Da
Secondary accessions: Q0VAL5
Alternative splicing: 2 isoforms:  Q9NXS3-1   Q9NXS3-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KLHL28: NX_Q9NXS3

Explore proteomics data for KLHL28 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KLHL28 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060128.2  
    ENSEMBL proteins: 
     ENSP00000379434   ENSP00000347193   ENSP00000462025   ENSP00000452061   ENSP00000452591  
     ENSP00000450788  

    KLHL28 Human Recombinant Protein Products:

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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for KLHL28 

     
    antibodies-online proteins for KLHL28 (2 products) 

     
    antibodies-online peptides for KLHL28

    KLHL28 Antibody Products:

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    Search for Antibodies for KLHL28 at Abcam
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    antibodies-online antibodies for KLHL28 (13 products) 

    KLHL28 Assay Products:

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    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for KLHL28 
    antibodies-online kits for KLHL28 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    BTBD: BTB/POZ domain containing
    KLHL: Kelch-like

    Selected InterPro protein domains (see all 8):
     IPR011043 Gal_Oxase/kelch_b-propeller
     IPR006652 Kelch_1
     IPR011333 BTB/POZ_fold
     IPR017096 Kelch-like_gigaxonin-typ
     IPR015916 Gal_Oxidase_b-propeller

    Graphical View of Domain Structure for InterPro Entry Q9NXS3

    ProtoNet protein and cluster: Q9NXS3

    2 Blocks protein domains:
    IPB000210 BTB/POZ domain
    IPB011705 BTB/Kelch-associated


    UniProtKB/Swiss-Prot: KLH28_HUMAN, Q9NXS3
    Similarity: Contains 1 BTB (POZ) domain
    Similarity: Contains 6 Kelch repeats


    Find genes that share domains with KLHL28           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with KLHL28           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for KLHL28:
     Decreased cell number  Increased cell number in G1, a 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for KLHL28

    miRNA
    Products:
        
    miRTarBase miRNAs that target KLHL28:
    hsa-mir-335-5p (MIRT019169), hsa-mir-29c-3p (MIRT020377), hsa-mir-130b-3p (MIRT020268), hsa-mir-361-5p (MIRT020091), hsa-mir-30b-5p (MIRT023404), hsa-mir-93-5p (MIRT028090)

    Block miRNA regulation of human, mouse, rat KLHL28 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KLHL28 (see all 108):
    hsa-miR-3678-3p hsa-miR-520e hsa-miR-607 hsa-miR-106a hsa-miR-3653 hsa-miR-30d hsa-miR-519a hsa-miR-890
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Predesigned siRNA for gene silencing in human, mouse, rat KLHL28

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: KLHL28 (NM_017658)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KLHL28
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLHL28

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for KLHL28 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHL28


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    endoplasmic reticulum1
    mitochondrion1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KLHL28
    Interactions:

        Search GeneGlobe Interaction Network for KLHL28

    2 Interacting proteins for KLHL28 (Q9NXS33) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AXIN1O151693I2D: score=1 
    AXIN2Q9Y2T13I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KLHL28 (KLH28)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KLHL28 gene: 
    NM_017658.3  

    Unigene Cluster for KLHL28:

    Kelch-like family member 28
    Hs.550906  [show with all ESTs]
    Unigene Representative Sequence: NM_017658
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396128(uc001wvq.3 uc001wvr.3) ENST00000355081 ENST00000579157
    ENST00000556500 ENST00000556239 ENST00000557468 ENST00000553817
    miRNA
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    Block miRNA regulation of human, mouse, rat KLHL28 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KLHL28 (see all 108):
    hsa-miR-3678-3p hsa-miR-520e hsa-miR-607 hsa-miR-106a hsa-miR-3653 hsa-miR-30d hsa-miR-519a hsa-miR-890
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KLHL28
    Predesigned siRNA for gene silencing in human, mouse, rat KLHL28
    Clone
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    OriGene clones in human, mouse for KLHL28 (see all 7)
    OriGene ORF clones in mouse, rat for KLHL28
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KLHL28 (NM_017658)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KLHL28
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLHL28
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for KLHL28
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KLHL28
      QuantiTect SYBR Green Assays in human, mouse, rat KLHL28
      QuantiFast Probe-based Assays in human, mouse, rat KLHL28

    Additional mRNA sequence: 

    AK090972.1 AK289855.1 BC012473.2 BC057794.1 BC121009.1 BC121010.1 

    7 DOTS entries:

    DT.408682  DT.92418158  DT.97794569  DT.40131028  DT.40310257  DT.100690232  DT.40119719 

    Selected AceView cDNA sequences (see all 41):

    BP350853 AI277394 AI247249 CA433205 BC012473 AA459242 AI349316 NM_017658 
    BX118266 AW270960 AA705318 AA459463 AW294280 AW118922 BQ710953 AA455180 
    BI222474 BP359589 BU543670 AL713035 BC057794 BP351027 BX461237 AK000088 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for KLHL28 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8
    SP1:                    -                                                                           
    SP2:                                                                                                
    SP3:                                      -     -                                                   
    SP4:                                                                                                
    SP5:                    -     -                                                                     


    ECgene alternative splicing isoforms for KLHL28

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KLHL28 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACCTTTTTA
    KLHL28 Expression
    About this image

    KLHL28 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KLHL28 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.550906
        Custom PCR Arrays for KLHL28
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHL28

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for KLHL28 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Klhl281 , 5 kelch-like 28 (Drosophila)5
    kelch-like 281
    91.13(n)1
    97.02(a)1
      12 (27.21 cM)5
    666891  NM_025707.31  NP_079983.11 
     649424405 
    chicken
    (Gallus gallus)
    Aves KLHL281 kelch-like 28 (Drosophila) 80.27(n)
    92.64(a)
      423596  XM_421484.3  XP_421484.1 
    lizard
    (Anolis carolinensis)
    Reptilia KLHL286
    kelch-like family member 28
    82(a)
    1 ↔ 1
    GL343274.1(197147-202029)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia klhl281 kelch-like family member 28 79.16(n)
    87.39(a)
      100493680  XM_002940536.2  XP_002940582.1 
    zebrafish
    (Danio rerio)
    Actinopterygii klhl281 kelch-like 28 (Drosophila) 68.88(n)
    83.4(a)
      100333404  XM_002667673.3  XP_002667719.2 


    ENSEMBL Gene Tree for KLHL28 (if available)
    TreeFam Gene Tree for KLHL28 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KLHL28 gene
    KLHL172  KLHL182  KLHL202  KLHL52  KLHL122  KEAP12  KLHL42  KLHL32  
    KLHL82  KLHL102  KLHL12  KLHL22  
    Selected SIMAP similar genes for KLHL28 using alignment to 6 protein entries:     KLH28_HUMAN (see all proteins) (see all similar genes):
    KLHL14    ZBTB44    KBTBD8    ZBTB21    ZNF295    KLHL20
    KLHL17    KBTBD3    KLHL3    KLHL26    KLHL4    KLHL1
    KLHL12    KLHL2    KLHL5    HIC1    KLHL32    ZBTB3

    Find genes that share paralogs with KLHL28           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KLHL28 (see all 616)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1916089621,2
    --45393037(+) TAGTAA/CACGTC 1 -- int10--------
    rs1133022421,2
    C--45393080(+) TTTTC-/TTTTTT 1 -- int11Minor allele frequency- T:0.00CSA 2
    rs788995011,2
    C--45393122(+) GGCTGG/TAATGC 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs574899651,2
    C,F--45393343(+) GCTGGT/GGTTAC 1 -- int11Minor allele frequency- G:0.00WA 2
    rs589208611,2
    C,F--45393372(+) CAGGCC/TGGGCC 1 -- int16Minor allele frequency- T:0.11WA CSA NA EA 363
    rs1178748121,2
    C,F--45393443(+) TACTAC/GCTATC 1 -- int11Minor allele frequency- G:0.03EA 120
    rs1837460171,2
    --45393469(+) AAGAGC/GTGAGC 1 -- int10--------
    rs171156901,2
    C,F,H--45393495(+) TGGTTC/TAGTTC 1 -- int119Minor allele frequency- T:0.12NA NS EA WA 1888
    rs1484072951,2
    C--45393712(+) AAGGTA/GCATGT 1 -- ut310--------
    rs1894988541,2
    --45393715(+) GTACAC/TGTTCA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for KLHL28 (45393522 - 45511525 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for KLHL28:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1259CNV Loss18451855
    nsv901841CNV Loss21882294
    nsv901832CNV Loss21882294
    nsv819173CNV Loss19587683

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KLHL28
    DNA2.0 Custom Variant and Variant Library Synthesis for KLHL28

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KLHL28 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with KLHL28)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Update on the Kelch-like (KLHL) gene family. (PubMed id 23676014)1 Dhanoa B.S....Friedman J.S. (Hum. Genomics 2013)
    4. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (Nat. Methods 2013)
    5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    6. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (Gene 1994)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54813 HGNC: 19741 AceView: BTBD5 Ensembl:ENSG00000179454 euGenes: HUgn54813
    ECgene: KLHL28 H-InvDB: KLHL28

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KLHL28 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KLHL28 gene:
    Search GeneIP for patents involving KLHL28

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
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