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KLHL23 Gene

protein-coding   GIFtS: 47
GCID: GC02P170551

Kelch-Like Family Member 23

(Previous name: kelch-like 23 (Drosophila))
  Search for KLHL23
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Kelch-Like Family Member 231 2
Kelch-Like 23 (Drosophila)1
DITHP2
Kelch-Like 232
Kelch-Like Protein 232

External Ids:    HGNC: 275061   Entrez Gene: 1512302   Ensembl: ENSG000002131607   UniProtKB: Q8NBE83   

Export aliases for KLHL23 gene to outside databases

Previous GC identifers: GC02P170417 GC02P170260 GC02P162442


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KLHL23 Gene:
KLHL23 (kelch-like family member 23) is a protein-coding gene. An important paralog of this gene is KLHL21.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the KLHL23 gene promoter:
         CREB   FOXF2   HSF2   FOXO1a   IRF-1   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   HNF-3beta   POU3F2   FOXL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKLHL23 promoter sequence
   Search Chromatin IP Primers for KLHL23

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KLHL23


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q31.1   Ensembl cytogenetic band:  2q31.1   HGNC cytogenetic band: 2q31.1

KLHL23 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLHL23 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P170551:  view genomic region     (about GC identifiers)

Start:
170,550,998 bp from pter      End:
170,633,499 bp from pter
Size:
82,502 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: KLH23_HUMAN, Q8NBE8 (See protein sequence)
Recommended Name: Kelch-like protein 23  
Size: 558 amino acids; 63923 Da
Sequence caution: Sequence=BAC04490.1; Type=Erroneous initiation;
Secondary accessions: Q8N9B9 Q96FT8

Explore the universe of human proteins at neXtProt for KLHL23: NX_Q8NBE8

Explore proteomics data for KLHL23 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys251, Lys265
  • Modification sites at PhosphoSitePlus

  • See KLHL23 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_653312.2  
    ENSEMBL proteins: 
     ENSP00000474581   ENSP00000272797   ENSP00000475081   ENSP00000376419   ENSP00000394732  
     ENSP00000400833  

    KLHL23 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for KLHL23
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    Novus Biologicals KLHL23 Protein
    Novus Biologicals KLHL23 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KLHL23

     
    Search eBioscience for Proteins for KLHL23 

    KLHL23 Antibody Products:

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    ThermoFisher Antibodies for KLHL23
    LSBio Antibodies in human, mouse, rat for KLHL23

    KLHL23 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for KLHL23
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for KLHL23
    Cloud-Clone Corp. CLIAs for KLHL23
    Search eBioscience for ELISAs for KLHL23 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    BTBD: BTB/POZ domain containing
    KLHL: Kelch-like

    Selected InterPro protein domains (see all 7):
     IPR006652 Kelch_1
     IPR011333 BTB/POZ_fold
     IPR017096 Kelch-like_gigaxonin-typ
     IPR015916 Gal_Oxidase_b-propeller
     IPR013069 BTB_POZ

    Graphical View of Domain Structure for InterPro Entry Q8NBE8

    ProtoNet protein and cluster: Q8NBE8

    2 Blocks protein domains:
    IPB000210 BTB/POZ domain
    IPB011705 BTB/Kelch-associated


    UniProtKB/Swiss-Prot: KLH23_HUMAN, Q8NBE8
    Similarity: Contains 1 BACK (BTB/Kelch associated) domain
    Similarity: Contains 1 BTB (POZ) domain
    Similarity: Contains 6 Kelch repeats


    Find genes that share domains with KLHL23           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with KLHL23           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KLHL23
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for KLHL23

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KLHL23
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KLHL23

    miRNA
    Products:
        
    miRTarBase miRNAs that target KLHL23:
    hsa-mir-10a-5p (MIRT047649), hsa-mir-128-3p (MIRT021998), hsa-mir-183-5p (MIRT047139), hsa-mir-24-3p (MIRT030436), hsa-mir-192-5p (MIRT026423), hsa-mir-215-5p (MIRT024447), hsa-mir-101-3p (MIRT027259)

    Block miRNA regulation of human, mouse, rat KLHL23 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KLHL23 (see all 29):
    hsa-miR-642a hsa-miR-520d-5p hsa-let-7d hsa-miR-3942-5p hsa-miR-624* hsa-miR-944 hsa-let-7c hsa-miR-3692
    SwitchGear 3'UTR luciferase reporter plasmidKLHL23 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for KLHL23
    Predesigned siRNA for gene silencing in human, mouse, rat KLHL23

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for KLHL23

    Clone
    Products:
         
    OriGene clones in human, mouse for KLHL23 (see all 8)
    OriGene ORF clones in mouse, rat for KLHL23
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KLHL23 (NM_144711)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KLHL23
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLHL23

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for KLHL23
    Browse ESI BIO Cell Lines and PureStem Progenitors for KLHL23 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHL23


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    cytoskeleton1
    peroxisome1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KLHL23
    Interactions:

        Search GeneGlobe Interaction Network for KLHL23

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    Selected Interacting proteins for KLHL23 (Q8NBE82, 3 ENSP000002727974) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ANXA1P040832, 3MINT-8247808 I2D: score=2 
    ANXA7P200732, 3MINT-8248483 I2D: score=2 
    CDKN1AP389362, 3MINT-8252024 I2D: score=2 
    TK1P041832, 3MINT-8273653 I2D: score=2 
    BNIP3LO602382, 3, ENSP000003700034MINT-8249630 I2D: score=2 STRING: ENSP00000370003
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KLHL23 (KLH23)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KLHL23 gene: 
    NM_144711.5  

    Unigene Cluster for KLHL23:

    Kelch-like family member 23
    Hs.655150  [show with all ESTs]
    Unigene Representative Sequence: NM_001199290
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000498202 ENST00000272797 ENST00000602521 ENST00000392647(uc002ufh.2 uc002ufi.2)
    ENST00000437875 ENST00000494387 ENST00000448589
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KLHL23 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KLHL23 (see all 29):
    hsa-miR-642a hsa-miR-520d-5p hsa-let-7d hsa-miR-3942-5p hsa-miR-624* hsa-miR-944 hsa-let-7c hsa-miR-3692
    SwitchGear 3'UTR luciferase reporter plasmidKLHL23 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KLHL23
    Predesigned siRNA for gene silencing in human, mouse, rat KLHL23
    Clone
    Products:
         
    OriGene clones in human, mouse for KLHL23 (see all 8)
    OriGene ORF clones in mouse, rat for KLHL23
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KLHL23 (NM_144711)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KLHL23
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLHL23
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for KLHL23
    OriGene qSTAR qPCR primer pairs in human, mouse for KLHL23
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KLHL23
      QuantiTect SYBR Green Assays in human, mouse, rat KLHL23
      QuantiFast Probe-based Assays in human, mouse, rat KLHL23

    Additional mRNA sequence: 

    AK095131.1 AK123454.1 BC010437.1 BC012382.1 BC016950.1 

    5 DOTS entries:

    DT.75139201  DT.422027  DT.95253930  DT.65288454  DT.97822293 

    Selected AceView cDNA sequences (see all 82):

    BQ879272 AA774547 AI139809 AI424984 BG106656 AI286028 BG029072 AA918024 
    AW592552 AI691127 AI304487 BX500650 CR602210 AA883515 AA348620 BM762290 
    AX746559 AI018553 AK090653 BM763772 BM820383 AW117330 BQ229603 AA348884 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KLHL23 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGAAGGTAA
    KLHL23 Expression
    About this image


    KLHL23 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Brain (Nervous System)    fully expand to see all 11 entries
             Thalamus
             Olfactory Bulb   
     
     Ovary (Reproductive System)
             Pre-Granulosa Cells Primordial Follicle
    KLHL23 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KLHL23 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655150
        Custom PCR Arrays for KLHL23
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for KLHL23
    OriGene qSTAR qPCR primer pairs in human, mouse for KLHL23
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KLHL23
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    QuantiFast Probe-based Assays in human, mouse, rat KLHL23
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHL23

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for KLHL23 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Klhl231 , 5 kelch-like 23 (Drosophila)5
    kelch-like 231
    90.2(n)1
    97.13(a)1
      2 (40.95 cM)5
    2773961  NM_177784.41  NP_808452.21 
     698219445 
    chicken
    (Gallus gallus)
    Aves KLHL231 kelch-like 23 (Drosophila) 71.48(n)
    73.3(a)
      429025  XM_426582.3  XP_426582.3 
    lizard
    (Anolis carolinensis)
    Reptilia KLHL236
    kelch-like family member 23
    77(a)
    1 ↔ 1
    GL343362.1(544684-549131)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia klhl231 kelch-like family member 23 68.94(n)
    71.15(a)
      100496894  XM_002934612.2  XP_002934658.1 
    zebrafish
    (Danio rerio)
    Actinopterygii klhl231 kelch-like 23 (Drosophila) 64.09(n)
    60.61(a)
      559613  XM_005169133.1  XP_005169190.1 


    ENSEMBL Gene Tree for KLHL23 (if available)
    TreeFam Gene Tree for KLHL23 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KLHL23 gene
    PHOSPHO2-KLHL23  KLHL212  KLHL62  KBTBD82  KLHL412  KBTBD122  KBTBD22  KLHL242  
    ENC12  KLHL382  KLHL292  KBTBD32  KLHL402  KBTBD72  KLHL302  KBTBD62  
    KLHL252  KLHL352  
    17 SIMAP similar genes for KLHL23 using alignment to 6 protein entries:     KLH23_HUMAN (see all proteins):
    KBTBD3    KLHL20    IVNS1ABP    KLHL17    KLHL18    KLHL13
    ENC1    KLHL25    KLHL5    KLHL1    KLHL10    KLHL2
    KLHL24    KLHL6    KLHL21    KLHL3    KLHL38

    Find genes that share paralogs with KLHL23           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for KLHL23:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2721119CNV Deletion23290073
    esv1784706CNV Insertion17803354
    esv1586748CNV Insertion17803354
    nsv834454CNV Loss17160897
    nsv10201CNV Loss18304495

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KLHL23
    DNA2.0 Custom Variant and Variant Library Synthesis for KLHL23

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease from the University of Copenhagen DISEASES database for KLHL23:
    cone-rod dystrophy

    Find genes that share disorders with KLHL23           About GenesLikeMe


    Export disorders for KLHL23 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KLHL23 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with KLHL23)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Update on the Kelch-like (KLHL) gene family. (PubMed id 23676014)1 Dhanoa B.S....Friedman J.S. (Hum. Genomics 2013)
    4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    6. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (Cell 2012)
    7. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    10. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 151230 HGNC: 27506 AceView: MGC22679 Ensembl:ENSG00000213160 euGenes: HUgn151230
    ECgene: KLHL23 H-InvDB: KLHL23

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KLHL23 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KLHL23 gene:
    Search GeneIP for patents involving KLHL23

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for KLHL23  
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     Block miRNA regulation of human, mouse, rat KLHL23 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing KLHL23
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KLHL23 Predesigned siRNA for gene silencing in human, mouse, rat KLHL23
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     Novus Tissue Slides
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     Browse ESI BIO Cell Lines and PureStem Progenitors for KLHL23
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     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KLHL23
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     Search Addgene for plasmids for KLHL23
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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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