KLHL20 Gene
protein-coding GIFtS: 50
GCID: GC01P173684
|
|
kelch-like family member 20(Previous name: kelch-like 20 (Drosophila) )
| |
Aliases
for KLHL20 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Kelch-Like Family Member 201 2 | | KLHLX2 | | KLEIP1 2 3 | | RP3-383J4.32 | | KHLHX1 2 | | Kelch Motif Containing Protein2 | | Kelch-Like ECT2-Interacting Protein2 3 | | Kelch-Like 202 | | Kelch-Like Protein X2 3 | | Kelch-Like ECT2 Interacting Protein2 | | Kelch-Like 20 (Drosophila)1 | | Kelch-Like Protein 202 |
Export aliases for KLHL20 gene to outside databasesPrevious GC identifers: GC01P170416 GC01P171950 GC01P144908 |
Summaries
for KLHL20 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KLHL20:
The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 44-56 aminoacid repeat motif. The kelch motif appears in many different polypeptide contexts and contains multiple potentialprotein-protein contact sites. Members of this family are present both throughout the cell and extracellularly, withdiverse activities. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: KLH20_HUMAN, Q9Y2M5Function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved ininterferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to itsdegradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator ofendothelial migration during angiogenesis by controlling the activation of Rho GTPases
Gene Wiki entry for KLHL20
|
Genomic Views
for KLHL20 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KLHL20 gene promoter:
Elk-1 NF-1 FOXO3 CUTL1 c-Ets-1 GATA-1 AREB6 FOXO4 FOXO3a
Other transcription factors
Search SABiosciences Chromatin IP Primers for KLHL20
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLHL20 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q25.1 Ensembl cytogenetic band: 1q25.1 HGNC cytogenetic band: 1q25.1KLHL20 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P173684: view genomic region
(about GC identifiers)
Start:
|
173,684,080 bp from pter |
End:
|
173,755,840 bp from pter |
Size:
|
71,761 bases |
Orientation:
|
plus strand |
|
Proteins
for KLHL20 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KLH20_HUMAN, Q9Y2M5 (See
protein sequence)Recommended Name: Kelch-like protein 20 Size: 609 amino acids; 67955 Da
Subunit: Component of the BCR(KLHL20) E3 ubiquitin ligase complex, at least composed of CUL3, KLHL20 and RBX1.Interacts with DAPK1. Interacts with F-actin. Interacts with IFN-gamma (IFNG)
Subcellular location: Cytoplasm, perinuclear region. Nucleus. Note=Localizes in the perinuclear region in normalconditions. Following IFN-alpha or IFN-gamma treatment, it is relocalized and sequestrated to the PML nuclear bodies,preventing DAPK1 ubiquitination
Secondary accessions: B3KMA0 Q5TZF2 Q5ZF45 Q9H457Explore the universe of human proteins at neXtProt for KLHL20: NX_Q9Y2M5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y2M5
KLHL20 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055273.2
ENSEMBL proteins: ENSP00000209884 ENSP00000443121 Reactome Protein details: Q9Y2M5
Human Recombinant Protein Products:
Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10): About this table
KLHL20 for ontologies About GeneDecksing
KLHL20 Antibody Products:
Assay Products for KLHL20: |
Protein
Domains /
Families
for KLHL20 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KLHL20 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q9Y2M5ProtoNet protein and cluster: Q9Y2M5 3 Blocks protein families: IPB000210 BTB/POZ domain IPB011498 Kelch IPB011705 BTB/Kelch-associated
UniProtKB/Swiss-Prot: KLH20_HUMAN, Q9Y2M5Similarity: Contains 1 BACK (BTB/Kelch associated) domainSimilarity: Contains 1 BTB (POZ) domainSimilarity: Contains 6 Kelch repeats |
Function
for KLHL20 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KLH20_HUMAN, Q9Y2M5Function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved ininterferon response. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to itsdegradation by the proteasome, thereby acting as a negative regulator of apoptosis. Also acts as a regulator ofendothelial migration during angiogenesis by controlling the activation of Rho GTPases
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KLHL20 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KLHL20
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: KLHL20 (NM_014458) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KLHL20 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLHL20 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHL20 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
KLHL20 for ontologies About GeneDecksing
|
Pathways & Interactions
for KLHL20 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Antigen processing: Ubiquitination & Proteasome degradation | | | 2 | Immune System | | | 3 | E-cadherin signaling in the nascent adherens junction | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for KLHL20
5 
Reactome Pathways for KLHL20
UniProtKB/Swiss-Prot: KLH20_HUMAN, Q9Y2M5Pathway: Protein modification; protein ubiquitination
KLHL20 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KLHL20
STRING Interaction
Network Preview (showing 5 interactants - click image to see 20)
5/31 Interacting proteins for KLHL20 (Q9Y2M51, 3 ENSP000002098844) via UniProtKB, MINT, STRING, and/or I2D (see all 31)
About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007010 | cytoskeleton organization |
TAS | 10888605 | | GO:0016567 | protein ubiquitination |
IDA | -- | | GO:0035455 | response to interferon-alpha |
TAS | -- | | GO:0043066 | negative regulation of apoptotic process |
IMP | -- | | GO:0043161 | proteasomal ubiquitin-dependent protein catabolic process |
IDA | -- |
KLHL20 for ontologies About GeneDecksing
|
Drugs & Compounds
for KLHL20 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KLHL20
Search CenterWatch for drugs/clinical trials and news about KLHL20 / KLH20
|
Transcripts
for KLHL20 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KLHL20 gene: NM_014458.3 Unigene Cluster for KLHL20: Kelch-like 20 (Drosophila) Hs.495035 [show with all ESTs]Unigene Representative Sequence: NM_0144586 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000479505 ENST00000209884(uc001gjc.3 uc010pmr.2 uc009wwf.3)
ENST00000483154 ENST00000493170(uc001gjd.3) ENST00000488983 ENST00000546011
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KLHL20 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KLHL20
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KLHL20 (NM_014458) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KLHL20 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLHL20 |
Additional cDNA sequence: AB026190.1 AJ844466.1 AK001430.1 AK300755.1 AK303487.1 AK308048.1 BC005253.1 BC063418.1 9 DOTS entries: DT.95289366 DT.40131446 DT.100718206 DT.309511 DT.40121082 DT.75111600 DT.95157784 DT.95244329 DT.121408851 24/108 AceView cDNA sequences (see all 108): BP368847 BQ432642 AI453173 BE677177 CB130282 BU154732 BM916593 AL527651 BG034013 CD557577 BU178781 AL705347 BI520238 AI927627 BQ932424 AI125291 AI091087 BF058391 AA431612 BC063418 BU164406 AI523210 AA486649 BE973704
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for KLHL20 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 |
|---|
|
| SP1: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KLHL20
|
Expression
for KLHL20 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KLHL20 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TATAACTTTT
About this image
See KLHL20 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KLHL20
SOURCE GeneReport for Unigene cluster: Hs.495035
SABiosciences Expression via Pathway-Focused PCR Array including KLHL20:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KLHL20
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KLHL20 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KLHL20 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KLHL20 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHL20 |
Orthologs
for KLHL20 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for KLHL20 gene from 6/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
KLHL201 |
kelch-like 20 (Drosophila) |
82.65(n)
99.01(a) |
|
425091 NM_001031329.1 NP_001026500.1 |
lizard
(Anolis carolinensis) |
Reptilia |
KLHL206 |
-- |
99(a) |
1 ↔ 1 |
4(71316612-71337011) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.114272 |
Transcribed sequence with strong similarity to protein more |
83.83(n) |
|
137727720 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufc33f092 |
Danio rerio cDNA clone MGC66288 IMAGE5412607, complete more |
78.64(n) |
|
BC057505.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
dbo1 |
diablo |
66.78(n)
80.94(a) |
|
53556 NM_080250.2 NP_524989.2 |
worm
(Caenorhabditis elegans) |
Secernentea |
R12E2.11 |
Protein R12E2.1 |
58.47(n)
60.52(a) |
|
172012 NM_058921.3 NP_491322.1 |
ENSEMBL Gene Tree for KLHL20 (if available)
TreeFam Gene Tree for KLHL20 (if available) |
Paralogs
for KLHL20 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KLHL20 gene
- KLHL172 KLHL182 KLHL52 KLHL122 KEAP12 KLHL282 KLHL42 IPP2
- KLHL32 KLHL82 KLHL102 KLHL12 KLHL22
18/40 SIMAP similar genes for KLHL20 using alignment to 3 protein entries: KLH20_HUMAN (see all proteins)
(see all similar genes):KLHL17 KLHL5 KLHL1 KLHL3 KLHL30 KLHL4
KLHL8 KLHL12 KLHL2 DKFZp686H07112 DKFZp686P15123 KLHL18
KLHL28 DKFZp761P1717 DKFZp781C1855 KBTBD8 ENC1 KLHL24
KLHL20 for paralogs About GeneDecksing
|
Genomic Variants
for KLHL20 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KLHL20 (173684080 - 173755840 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KLHL20: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KLHL20 |
|
Disorders
/ Diseases
for KLHL20 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KLHL20 for disorders About GeneDecksing
6  diseases for KLHL20: About MalaCardsintrahepatic cholangiocarcinoma prostate cancer, progression of cholangiocarcinoma prostate cancer
prostatitis hypoxia
Export disorders for KLHL20 gene to outside databases
|
Publications
for KLHL20 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KLHL20 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with KLHL20) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Novel kelch-like protein, KLEIP, is involved in actin assembly at cell-cell contact sites of Madin-Darby canine kidney cells. (PubMed id 14668487)1, 2, 3, 9 Hara T.... Miki T. (2004)
- The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses. (PubMed id 20389280)1, 2, 3 Lee Y.R.... Chen R.H. (2010)
- The BTB-Kelch protein KLEIP controls endothelial migration and sprouting angiogenesis. (PubMed id 17395875)1, 2, 9 Nacak T.G....Kroll J. (2007)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- A Cullin3-KLHL20 Ubiquitin ligase-dependent pathway t argets PML to potentiate HIF-1 signaling and prostate cancer progression. (PubMed id 21840486)1 Yuan W.C....Chen R.H. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Kelch-like 20 up-regulates the expression of hypoxia- inducible factor-2I+ through hypoxia- and von Hippel-Lindau tumor suppressor pro tein-independent regulatory mechanisms. (PubMed id 21888897)1 Higashimura Y....Nakano Y. (2011)
|
External Searches for KLHL20 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KLHL20 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KLHL20 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KLHL20 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KLHL20 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KLHL20 gene:
Search GeneIP for patents involving KLHL20
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KLHL20 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KLHL20 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KLHL20 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KLHL20 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KLHL20 | | OriGene 3'-UTR Clone for KLHL20 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KLHL20 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KLHL20 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KLHL20 | | OriGene Custom Protein Services for KLHL20 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KLHL20 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KLHL20 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLHL20 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KLHL20 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KLHL20 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KLHL20 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for KLHL20 |
| |  |  |  |  | | | | |
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 | | | KLHL20 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHL20 |
|  |  |  | | | | ThermoFisher Antibodies for KLHL20 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLHL20 |
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