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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

KLHDC4 Gene

protein-coding GIFtS: 45
GCID: GC16M087741

kelch domain containing 4

Explore 1 disease affiliated with
KLHDC4 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Kelch Domain Containing 4¹ ²
DKFZp434G0522¹
Kelch Domain-Containing Protein 4²

External Ids:	HGNC: 25272¹	Entrez Gene: 54758²	Ensembl: ENSG00000104731⁷	UniProtKB: Q8TBB5³

Export aliases for KLHDC4 gene to outside databases

Previous GC identifers: GC00U916984 GC16M086298 GC16M073482

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000016.9 NC_018927.1 NT_010498.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the KLHDC4 gene promoter:
SRF AML1a GCNF SRF (504 AA) FOXL1 POU2F1 POU2F1a GCNF-1 GCNF-2 Hlf
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: KLHDC4 promoter sequence

Search SABiosciences Chromatin IP Primers for KLHDC4

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLHDC4

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q24.3 Ensembl cytogenetic band: 16q24.2 HGNC cytogenetic band: 16q24

KLHDC4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLHDC4 gene location

GeneLoc information about chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16M087741: view genomic region (about GC identifiers)

Start:	87,730,091 bp from pter	End:	87,799,598 bp from pter
Size:	69,508 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: KLDC4_HUMAN, Q8TBB5 (See protein sequence)

Recommended Name: Kelch domain-containing protein 4

Size: 520 amino acids; 57892 Da

Secondary accessions: D3DUN3 D3DUN4 D3DUN5 Q96F29 Q9BVN3

Alternative splicing: 3 isoforms: Q8TBB5-1 Q8TBB5-2 Q8TBB5-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KLHDC4: NX_Q8TBB5

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8TBB5

KLHDC4 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001171783.1 NP_001171785.1 NP_060036.2

ENSEMBL proteins:

ENSP00000457570 ENSP00000262530 ENSP00000325717 ENSP00000270583 ENSP00000455824

ENSP00000455780 ENSP00000455666 ENSP00000455214 ENSP00000457990 ENSP00000457098

ENSP00000454681 ENSP00000457857

Human Recombinant Protein Products:

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	Uscn Proteins for KLHDC4

KLHDC4 Antibody Products:

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	Uscn Antibodies for KLHDC4
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Assay Products for KLHDC4:

	Browse Kits and Assays available from EMD Millipore
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	GenScript Custom Assay Services for KLHDC4
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for KLHDC4

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

KLHDC4 for domains About GeneDecksing

2 InterPro domains/families:

IPR011498 Kelch_2

IPR015915 Kelch-typ_b-propeller

Graphical View of Domain Structure for InterPro Entry Q8TBB5

ProtoNet protein and cluster: Q8TBB5

1 Blocks protein family: IPB011498 Kelch

UniProtKB/Swiss-Prot: KLDC4_HUMAN, Q8TBB5

Similarity: Contains 6 Kelch repeats

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone: KLHDC4 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KLHDC4
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate KLHDC4
		SwitchGear 3'UTR luciferase reporter plasmid: KLHDC4 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KLHDC4 (see all 4) OriGene shRNA RFP: KLHDC4 OriGene siRNA: KLHDC4
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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for KLHDC4

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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KLHDC4 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KLHDC4 (see all 4) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for KLHDC4
		Search LifeMap BioReagents cell lines for KLHDC4

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHDC4

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for KLHDC4

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

5/12 Interacting proteins for KLHDC4 (Q8TBB5³ ENSP00000270583⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 12)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PNO1	Q9NRX1³, ENSP00000263657⁴	I2D: score=4 STRING: ENSP00000263657
WDR1	O75083³	I2D: score=5
PHB	P35232³	I2D: score=4
DYNC1H1	Q14204³	I2D: score=3
HSPA8	P11142³	I2D: score=2

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for KLHDC4
Search CenterWatch for drugs/clinical trials and news about KLHDC4 / KLDC4

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for KLHDC4 gene (3 alternative transcripts):

NM_001184854.1 NM_001184856.1 NM_017566.3

Unigene Cluster for KLHDC4:

Kelch domain containing 4

Hs.123450 [show with all ESTs]

Unigene Representative Sequence: AY251274

18/25 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 25):

ENST00000568444 ENST00000567298(uc002fkh.1) ENST00000568346 ENST00000568499

ENST00000316853(uc010cht.2) ENST00000353170 ENST00000347925(uc002fkj.3)

ENST00000566349 ENST00000270583(uc002fki.3 uc002fkl.3) ENST00000569487

ENST00000562155 ENST00000562261 ENST00000566661(uc010chu.1) ENST00000562913

ENST00000567513 ENST00000562872 ENST00000564484 ENST00000565328

miRNA Products:		OriGene 3'-UTR Clone: KLHDC4 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KLHDC4
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate KLHDC4
		SwitchGear 3'UTR luciferase reporter plasmid: KLHDC4 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KLHDC4 (see all 4) OriGene shRNA RFP: KLHDC4 OriGene siRNA: KLHDC4
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KLHDC4

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KLHDC4 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KLHDC4 (see all 4) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 3): KLHDC4 (NM_017566)
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLHDC4

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KLHDC4 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KLHDC4

Additional cDNA sequence:

AK001742.1 AK023986.1 AK024496.1 AK057211.1 AK092895.1 AK097097.1 AK098630.1 AL133107.1

AY251274.1 BC001044.2 BC011680.2 BC022969.1

21 DOTS entries:

DT.91741629 DT.309421 DT.100036618 DT.91741634 DT.100036617 DT.95151206 DT.75148878 DT.100787895

DT.91675958 DT.120710349 DT.120710391 DT.92053471 DT.100787896 DT.101978603 DT.120710322 DT.120710347

DT.120710380 DT.120710382 DT.120710384 DT.91658278 DT.120710400

24/190 AceView cDNA sequences (see all 190):

AW137862 AI276461 BM715028 BQ013761 AK098630 CR600527 BC001044 BG574152

BX096670 BE280463 AI652077 AI160590 BE407092 NM_017566 CA455055 AK127434

BF001898 BM760792 AL133107 AK092895 BQ017135 CB529461 BM556502 AI934942

GeneLoc Exon Structure

5/24 Alternative Splicing Database (ASD) splice patterns (SP) for KLHDC4 (see all 24) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	·	1f	^	2	^	3	^	4a	·	4b	^	5	^	6a	·	6b	·	6c	^	7a	·	7b	·	7c	·	7d	^	8a	·	8b	·	8c	·	8d	^	9	^	10	^	11a	·	11b	·
SP1:													-		-		-				-						-		-																-		-		-
SP2:													-		-		-				-						-		-																-		-		-		-
SP3:													-		-		-		-		-		-		-		-		-																-		-		-
SP4:																																															-		-
SP5:																																													-		-		-

ExUns:	11c	·	11d	·	11e	^	12	^	13a	·	13b	·	13c	·	13d	^	14	^	15	^	16a	·	16b	·	16c	^	17a	·	17b	^	18
SP1:					-		-														-						-
SP2:	-		-		-		-														-						-
SP3:					-		-														-						-
SP4:					-		-														-						-
SP5:					-		-														-

ECgene alternative splicing isoforms for KLHDC4

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

KLHDC4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

KLHDC4 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Intermediate Mesoderm

Intermediate Mesoderm

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See KLHDC4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KLHDC4

SOURCE GeneReport for Unigene cluster: Hs.123450

SABiosciences Custom PCR Arrays for KLHDC4

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KLHDC4 Browse OriGene validated miRNA SYBR primer pairs
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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHDC4

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for KLHDC4 gene from 9/25 species (see all 25) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Klhdc4^{1 , 5}	kelch domain containing 4^{1, 5}	80.6(n)¹ 79.96(a)¹		8 (70.76 cM)⁵ 234825¹ NM_145605.2¹ NP_663580.2¹ 121796313⁵
chicken (Gallus gallus)	Aves	KLHDC4¹	kelch domain containing 4	73.62(n) 75.48(a)		415831 NM_001030578.1 NP_001025749.1
lizard (Anolis carolinensis)	Reptilia	KLHDC4⁶	--	52(a)	1 ↔ 1	GL344378.1(1448-11439)
African clawed frog (Xenopus laevis)	Amphibia	MGC53395²	hypothetical protein MGC53395	72.86(n)		BC043978.1
zebrafish (Danio rerio)	Actinopterygii	wufb95f04²	Transcribed sequence with weak similarity to protein more	77.64(n)		BQ617456.1
fruit fly (Drosophila melanogaster)	Insecta	CG4069¹	CG4069	52.85(n) 43.5(a)		39437 NM_140333.2 NP_648590.1
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	KEL3(YPL263C)⁴ KEL3¹	Cytoplasmic protein of unknown function⁴ Kel3p¹	45.55(n)¹ 33.4(a)¹		16(46506-44551)⁴ 855865^{1, 4} NP_015060.1^{1, 4}
thale cress (Arabidopsis thaliana)	eudicotyledons	AT5G50310¹	kelch repeat-containing protein	50.5(n) 42.12(a)		835096 NM_124410.3 NP_568723.1
rice (Oryza sativa)	Liliopsida	Os04g0483600¹	hypothetical protein	48.75(n) 41.41(a)		4336203 NM_001059661.1 NP_001053126.1

ENSEMBL Gene Tree for KLHDC4 (if available)
TreeFam Gene Tree for KLHDC4 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for KLHDC4 gene

1 SIMAP similar gene for KLHDC4 using alignment to 8 protein entries: KLDC4_HUMAN (see all proteins):

DKFZp434G0522

KLHDC4 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for KLHDC4
PGOHUM00000246106

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 16 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs188957596^1,2		--	87740919(+)	`AGCCTC/GCCTTC`	3	--	int¹		0	--	--	--	--
rs56168079^1,2	C,	--	87740930(+)	`CTGTCG/ACTTTG`	3	--	int¹		2		WA	120
rs150224460^1,2		--	87740946(+)	`GCTAAA/TCCTAA`	3	--	int¹		0	--	--	--	--
rs192940241^1,2		--	87740996(+)	`CCACAG/TCCTCC`	3	--	int¹		0	--	--	--	--
rs139168324^1,2		--	87741012(+)	`ACCACA/GCGGCG`	3	--	int¹		0	--	--	--	--
rs142980549^1,2		--	87741077(+)	`CCCCCA/GTGTGC`	3	--	int¹		0	--	--	--	--
rs147467698^1,2		--	87741116(+)	`AGAACC/TGGGAA`	3	--	int¹		0	--	--	--	--
rs77016861^1,2	C,	--	87741168(+)	`AGAGGC/TTGATC`	3	--	int¹		4		CSA WA NA EA	359
rs140187640^1,2		--	87741178(+)	`CCCAAC/GTGTGA`	3	--	int¹		0	--	--	--	--
rs11859521^1,2	C,F,H,	--	87741225(+)	`CAGAAG/AGAAAG`	3	--	int¹		3		NA WA	244

HapMap Linkage Disequilibrium report for KLHDC4 (87730091 - 87799598 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for KLHDC4
2 CNVs: 67077 77453
4 Indels: 25714 25715 41809 34403

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KLHDC4

DNA2.0 Custom Variant and Variant Library Synthesis for KLHDC4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

KLHDC4 for disorders About GeneDecksing

1 disease for KLHDC4: About MalaCards

malaria

Export disorders for KLHDC4 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for KLHDC4 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with KLHDC4)

Utopia: connect your pdf to the dynamic
world of online information

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)¹ Lee O.H....Songyang Z. (2011)
Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)² Cantin G.T....Yates J.R. III (2008)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)¹ Suzuki Y.... Sugano S. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)¹ Beausoleil S.A....Gygi S.P. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 54758	HGNC: 25272	AceView: KLHDC4	Ensembl:ENSG00000104731	euGenes: HUgn54758
ECgene: KLHDC4	H-InvDB: KLHDC4

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for KLHDC4	Pharmacogenomics, SNPs, Pathways

Intellectual Property for KLHDC4 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for KLHDC4 gene:
Search GeneIP for patents involving KLHDC4

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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KLHDC4 Gene

kelch domain containing 4

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KLHDC4 Gene

kelch domain containing 4

Aliasesfor KLHDC4 gene

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for KLHDC4 gene

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for KLHDC4 gene

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for KLHDC4 gene

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for KLHDC4 gene

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for KLHDC4 gene

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for KLHDC4 gene

Disorders / Diseases
for KLHDC4 gene

Publications
for KLHDC4 gene

Intellectual Property
for KLHDC4 gene

Products
for KLHDC4 gene