Aliases for KLHDC3 Gene
External Ids for KLHDC3 Gene
Previous GeneCards Identifiers for KLHDC3 Gene
The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2, a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to be expressed specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasma and meiotic chromatin, suggesting that this gene may be involved in meiotic recombination. [provided by RefSeq, Jun 2012]
GeneCards Summary for KLHDC3 Gene
KLHDC3 (Kelch Domain Containing 3) is a Protein Coding gene. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Unfolded Protein Response. GO annotations related to this gene include chromatin binding. An important paralog of this gene is KLHDC1.
UniProtKB/Swiss-Prot for KLHDC3 Gene
May be involved in meiotic recombination process