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KLHDC10 Gene

protein-coding   GIFtS: 50
GCID: GC07P129710

Kelch Domain Containing 10

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Kelch Domain Containing 101 2     Scruin Like At The Midline Homolog2
Scruin Like At The Midline Homolog (Drosophila)1     slim2
PNAS-1192     KIAA02653
Kelch Domain-Containing Protein 102     SLIM5

External Ids:    HGNC: 221941   Entrez Gene: 230082   Ensembl: ENSG000001286077   OMIM: 6151525   UniProtKB: Q6PID83   

Export aliases for KLHDC10 gene to outside databases

Previous GC identifers: GC07P129498 GC07P124072


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KLHDC10 Gene:
KLHDC10 (kelch domain containing 10) is a protein-coding gene. An important paralog of this gene is KLHDC2.

UniProtKB/Swiss-Prot: KLD10_HUMAN, Q6PID8
Function: Participates in the oxidative stress-induced cell death through MAP3K5 activation. Inhibits PPP5C
phosphatase activity on MAP3K5




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KLHDC10 gene promoter:
         Max1   GATA-1   AREB6   Max   CBF-A   CBF-B   STAT3   c-Myc   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): KLHDC10 promoter sequence
   Search Chromatin IP Primers for KLHDC10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KLHDC10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q32.2   Ensembl cytogenetic band:  7q32.2   HGNC cytogenetic band: 7q32.2

KLHDC10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLHDC10 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P129710:  view genomic region     (about GC identifiers)

Start:
129,710,349 bp from pter      End:
129,775,560 bp from pter
Size:
65,212 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 129,095,715-129,160,935     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: KLD10_HUMAN, Q6PID8 (See protein sequence)
Recommended Name: Kelch domain-containing protein 10  
Size: 442 amino acids; 49098 Da
Subunit: Interacts with CUL2, TCEB1 and TCEB2; may be the substrate recognition component of an E3 ubiquitin
ligase complex. Interacts (via the 6 Kelch repeats) with PPP5C
Developmental stage: Expressed in fetal brain, liver, lung, kidney and placenta
Sequence caution: Sequence=BAA13395.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q86Y99 Q92554
Alternative splicing: 2 isoforms:  Q6PID8-1   Q6PID8-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KLHDC10: NX_Q6PID8

Explore proteomics data for KLHDC10 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KLHDC10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055812.1  
    ENSEMBL proteins: 
     ENSP00000334140   ENSP00000420083   ENSP00000420034  

    KLHDC10 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for KLHDC10

     
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    ThermoFisher Antibody for KLHDC10
    LSBio Antibodies in human, mouse, rat for KLHDC10

    KLHDC10 Assay Products:

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    Search eBioscience for ELISAs for KLHDC10 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR006652 Kelch_1
     IPR015915 Kelch-typ_b-propeller

    Graphical View of Domain Structure for InterPro Entry Q6PID8

    ProtoNet protein and cluster: Q6PID8

    UniProtKB/Swiss-Prot: KLD10_HUMAN, Q6PID8
    Similarity: Contains 6 Kelch repeats


    Find genes that share domains with KLHDC10           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KLD10_HUMAN, Q6PID8
    Function: Participates in the oxidative stress-induced cell death through MAP3K5 activation. Inhibits PPP5C
    phosphatase activity on MAP3K5

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with KLHDC10           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KLHDC10
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for KLHDC10

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KLHDC10
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KLHDC10

    miRNA
    Products:
        
    miRTarBase miRNAs that target KLHDC10:
    hsa-mir-18a-3p (MIRT040901)

    Block miRNA regulation of human, mouse, rat KLHDC10 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KLHDC10 (see all 95):
    hsa-miR-548j hsa-miR-579 hsa-miR-26a-2* hsa-miR-200a hsa-miR-877* hsa-miR-3142 hsa-miR-4325 hsa-miR-383
    SwitchGear 3'UTR luciferase reporter plasmidKLHDC10 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for KLHDC10
    Search Predesigned siRNA for gene silencing in human, mouse, rat KLHDC10

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for KLHDC10 (see all 6)
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    GenScript: all cDNA clones in your preferred vector: KLHDC10 (NM_014997)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KLHDC10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLHDC10

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHDC10


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KLD10_HUMAN, Q6PID8: Nucleus. Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with KLHDC10           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KLHDC10
    Interactions:

        Search GeneGlobe Interaction Network for KLHDC10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for KLHDC10 (Q6PID83 ENSP000003341404) via UniProtKB, MINT, STRING, and/or I2D (see all 294)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KLHDC10 (KLD10)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KLHDC10 gene: 
    NM_014997.3  

    Unigene Cluster for KLHDC10:

    Kelch domain containing 10
    Hs.520710  [show with all ESTs]
    Unigene Representative Sequence: NM_014997
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000335420(uc003vpj.2 uc003vpk.2 uc010lmb.2) ENST00000463413
    ENST00000468226 ENST00000495724
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KLHDC10 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KLHDC10 (see all 95):
    hsa-miR-548j hsa-miR-579 hsa-miR-26a-2* hsa-miR-200a hsa-miR-877* hsa-miR-3142 hsa-miR-4325 hsa-miR-383
    SwitchGear 3'UTR luciferase reporter plasmidKLHDC10 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KLHDC10
    Search Predesigned siRNA for gene silencing in human, mouse, rat KLHDC10
    Clone
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    OriGene clones in human, mouse for KLHDC10 (see all 6)
    OriGene ORF clones in mouse, rat for KLHDC10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KLHDC10 (NM_014997)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KLHDC10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLHDC10
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for KLHDC10
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KLHDC10
      QuantiTect SYBR Green Assays in human, mouse, rat KLHDC10
      QuantiFast Probe-based Assays in human, mouse, rat KLHDC10

    Additional mRNA sequence: 

    AF268385.1 AF277175.1 AF277177.1 BC009977.2 BC036464.2 BC044884.1 D87454.1 

    7 DOTS entries:

    DT.316710  DT.97806266  DT.92432685  DT.95079754  DT.40253332  DT.95079753  DT.95218936 

    Selected AceView cDNA sequences (see all 270):

    BU146480 N74019 AI742761 AA426514 W60558 CD370736 AA418990 BM129311 
    AI969301 BU162365 W77803 BQ787670 AI056315 BM674591 BM090987 AW044132 
    AA364983 AI832221 BM701592 CF529023 BM129515 AA831130 AA330937 BC009977 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for KLHDC10    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:              -                                                         
    SP2:                                                                        
    SP3:              -     -                                                   


    ECgene alternative splicing isoforms for KLHDC10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KLHDC10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCATATGATC
    KLHDC10 Expression
    About this image


    KLHDC10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Trophoblast (Extraembryonic Tissues)
             Mural Trophectoderm Cells Mural Trophectoderm
     
     Testis (Reproductive System)
    KLHDC10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KLHDC10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.520710
        Custom PCR Arrays for KLHDC10
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLHDC10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for KLHDC10 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Klhdc101 , 5 kelch domain containing 101, 5 90.81(n)1
    97.04(a)1
      6 (12.52 cM)5
    767881  NM_029742.21  NP_084018.11 
     304018685 
    chicken
    (Gallus gallus)
    Aves KLHDC101 kelch domain containing 10 80.46(n)
    89.2(a)
      427683  XM_004937414.1  XP_004937471.1 
    lizard
    (Anolis carolinensis)
    Reptilia KLHDC106
    kelch domain containing 10
    84(a)
    1 ↔ 1
    GL343708.1(195433-221102)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.213262 Xenopus laevis transcribed sequence with weak similarity more 78.81(n)    BX843490.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc556632 hypothetical protein MGC55663 77.77(n)   393231  BC048880.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta slim1 scruin like at the midline 48.59(n)
    42.78(a)
      37121  NM_166289.2  NP_725794.2 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y67H2A.21 CELE_Y67H2A.2 45.3(n)
    34.67(a)
      178286  NM_001047591.3  NP_001041056.1 


    ENSEMBL Gene Tree for KLHDC10 (if available)
    TreeFam Gene Tree for KLHDC10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KLHDC10 gene
    KLHDC22  KLHDC32  HCFC12  KLHDC12  LZTR12  RABEPK2  HCFC22  

    Find genes that share paralogs with KLHDC10           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KLHDC10 (see all 1223)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1441359501,2
    --129708361(+) GATTAC/TAGACA 1 -- us2k10--------
    rs127069151,2
    C,F--129708425(+) CCCAGT/CTGATT 1 -- us2k1 tfbs39Minor allele frequency- C:0.21NA CSA WA EA 370
    rs1883252091,2
    --129708432(+) GATTAA/CTTAAA 1 -- us2k10--------
    rs1914198311,2
    --129708449(+) TACTTA/GAGAAT 1 -- us2k10--------
    rs1836902451,2
    --129708550(+) TAGCCA/GGAGCA 1 -- us2k10--------
    rs102701181,2
    C,F--129708671(+) AAACAT/AGTAAA 1 -- us2k12Minor allele frequency- A:0.25NA WA 4
    rs1887610851,2
    --129708740(+) CACCTA/GTAATC 1 -- us2k10--------
    rs1123038321,2
    C,F--129708886(+) GCTACC/TTGGGA 1 -- us2k11Minor allele frequency- T:0.00WA 2
    rs102578921,2
    C,F--129708971(+) gtctcG/Agcgac 1 -- us2k14Minor allele frequency- A:0.16NA WA 124
    rs3683282561,2
    C--129708994(+) CGTCTA/CAAAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for KLHDC10 (129710349 - 129775560 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for KLHDC10:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv366394CNV Loss16902084
    nsv510968CNV Complex20534489

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KLHDC10
    DNA2.0 Custom Variant and Variant Library Synthesis for KLHDC10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615152    OMIM disorders: --


    Find genes that share disorders with KLHDC10           About GenesLikeMe

    Genetic Association Database (GAD): KLHDC10

    Export disorders for KLHDC10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KLHDC10 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with KLHDC10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The Kelch repeat protein KLHDC10 regulates oxidative stress-induced ASK1 activation by suppressing PP5. (PubMed id 23102700)1, 2 Sekine Y....Ichijo H. (Mol. Cell 2012)
    2. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    3. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)1, 2 Nagase T.... Nomura N. (DNA Res. 1996)
    4. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    5. Network organization of the human autophagy system. (PubMed id 20562859)1 Behrends C....Harper J.W. (Nature 2010)
    6. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Imprinting analysis of 10 genes and/or transcripts in a 1.5-Mb MEST- flanking region at human chromosome 7q32. (PubMed id 14962666)2 Yamada T.... Kishino T. (Genomics 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23008 HGNC: 22194 AceView: KIAA0265 Ensembl:ENSG00000128607 euGenes: HUgn23008
    ECgene: KLHDC10 H-InvDB: KLHDC10

    (According to HUGE)
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    HUGE: KIAA0265

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for KLHDC10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for KLHDC10 gene:
    Search GeneIP for patents involving KLHDC10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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