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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KLF9 Gene

protein-coding   GIFtS: 53
GCID: GC09M072999

Kruppel-Like Factor 9

(Previous name: basic transcription element binding protein 1)
(Previous symbol: BTEB1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Kruppel-Like Factor 91 2     Transcription Factor BTEB12 3
BTEB11 2 3 5     BTE-Binding Protein 12 3
BTEB2 3 5     GC-Box-Binding Protein 12 3
Basic Transcription Element Binding Protein 11 2     Krueppel-Like Factor 92
Basic Transcription Element-Binding Protein 12 3     

External Ids:    HGNC: 11231   Entrez Gene: 6872   Ensembl: ENSG000001191387   OMIM: 6029025   UniProtKB: Q138863   

Export aliases for KLF9 gene to outside databases

Previous GC identifers: GC09M070230 GC09M072189 GC09M042839


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KLF9 Gene:
The protein encoded by this gene is a transcription factor that binds to GC box elements located in the promoter.
Binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC
box elements activates transcription. (provided by RefSeq, Jul 2008)

GeneCards Summary for KLF9 Gene: 
KLF9 (Kruppel-like factor 9) is a protein-coding gene. Diseases associated with KLF9 include otosclerosis, and endometrial carcinoma. GO annotations related to this gene include DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is KLF1.

UniProtKB/Swiss-Prot: KLF9_HUMAN, Q13886
Function: Transcription factor that binds to GC box promoter elements. Selectively activates mRNA synthesis from
genes containing tandem repeats of GC boxes but represses genes with a single GC box

Gene Wiki entry for KLF9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.2  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KLF9 gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-1   E2F   Sp1   ARP-1   E2F-2   LCR-F1   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): KLF9 promoter sequence
   Search SABiosciences Chromatin IP Primers for KLF9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLF9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q13   Ensembl cytogenetic band:  9q21.12   HGNC cytogenetic band: 9q21.11

KLF9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLF9 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M072999:  view genomic region     (about GC identifiers)

Start:
72,999,503 bp from pter      End:
73,029,573 bp from pter
Size:
30,071 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KLF9_HUMAN, Q13886 (See protein sequence)
Recommended Name: Krueppel-like factor 9  
Size: 244 amino acids; 27235 Da
Subcellular location: Nucleus
Secondary accessions: B2R943 Q16196

Explore the universe of human proteins at neXtProt for KLF9: NX_Q13886

Explore proteomics data for KLF9 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q13886

  • KLF9 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KLF9 Protein Expression
    REFSEQ proteins: NP_001197.1  
    ENSEMBL proteins: 
     ENSP00000366330  

    Human Recombinant Protein Products for KLF9: 
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    Novus Biologicals KLF9 Protein
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KLF9 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    KLF9 for ontologies           About GeneDecksing



    KLF9 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for KLF9


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZNF: Zinc fingers, C2H2-type
    KLF: Kruppel-like transcription factors

    3 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q13886

    ProtoNet protein and cluster: Q13886

    1 Blocks protein domain: IPB007086 C2H2-type zinc finger signature

    UniProtKB/Swiss-Prot: KLF9_HUMAN, Q13886
    Similarity: Belongs to the Sp1 C2H2-type zinc-finger protein family
    Similarity: Contains 3 C2H2-type zinc fingers


    KLF9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KLF9_HUMAN, Q13886
    Function: Transcription factor that binds to GC box promoter elements. Selectively activates mRNA synthesis from
    genes containing tandem repeats of GC boxes but represses genes with a single GC box

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity TAS1356762
    GO:0008270zinc ion binding ----
    GO:0046872metal ion binding IEA--
         
    KLF9 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Klf9):
     behavior/neurological 

    KLF9 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for KLF9 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KLF9

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KLF9 
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    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidKLF9 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLF9


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for KLF9 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Diurnally regulated genes with circadian orthologs
    Diurnally regulated genes with circadian orthologs


    1 BioSystems Pathway for KLF9
        Diurnally regulated genes with circadian orthologs



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KLF9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/6 Interacting proteins for KLF9 (Q138863 ENSP000003663304) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PGRP064013, ENSP000003251204I2D: score=2 STRING: ENSP00000325120
    SP1P080473, ENSP000003293574I2D: score=1 STRING: ENSP00000329357
    SIN3AQ96ST33, ENSP000003536224I2D: score=1 STRING: ENSP00000353622
    HDAC7ENSP000000800594STRING: ENSP00000080059
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0006357regulation of transcription from RNA polymerase II promoter TAS1356762
    GO:0007566embryo implantation IEA--
    GO:0050847progesterone receptor signaling pathway IEA--

    KLF9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    KLF9 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KLF9

    3 Novoseek inferred chemical compound relationships for KLF9 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    progesterone 45.3 27 16384861 (6), 11751593 (6), 10342837 (5), 17717078 (1)
    chloramphenicol 39.4 1 8257632 (1)
    zinc 28.6 3 8479902 (1), 17548317 (1), 9721211 (1)

    Search CenterWatch for drugs/clinical trials and news about KLF9

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KLF9 gene: 
    NM_001206.2  

    Unigene Cluster for KLF9:

    Kruppel-like factor 9
    Hs.150557  [show with all ESTs]
    Unigene Representative Sequence: NM_001206
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000377126(uc004aht.3)
    miRNA
    Products:
         
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    8/60 QIAGEN miScript miRNA Assays for microRNAs that regulate KLF9 (see all 60):
    hsa-miR-124* hsa-miR-579 hsa-miR-549 hsa-miR-548j hsa-miR-140-5p hsa-miR-607 hsa-miR-429 hsa-let-7d
    SwitchGear 3'UTR luciferase reporter plasmidKLF9 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KLF9
    Clone
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    OriGene ORF clones in mouse, rat for KLF9
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KLF9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLF9
    Sirion Biotech Customized lentivirus for stable overexpression of KLF9 
                         Customized lentivirus expression plasmids for stable overexpression of KLF9 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for KLF9
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KLF9
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KLF9
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KLF9

    Additional mRNA sequence: 

    AB451404.1 AK313631.1 BC069431.1 BC074879.2 BC074880.2 D31716.1 S72504.1 

    6 DOTS entries:

    DT.418246  DT.92434819  DT.92434820  DT.100792014  DT.95165364  DT.97812180 

    24/312 AceView cDNA sequences (see all 312):

    BU077421 AI091332 BU069440 AA180136 CD677401 BX480333 BX951455 AA910521 
    BE222308 AI416998 AI522233 AI308806 BM705037 AA988001 BQ771906 AA424380 
    AA977206 AW340262 CK825403 AW235052 N66436 CB143737 BM856189 BE222329 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KLF9 expression in normal human tissues (normalized intensities)      KLF9 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTCTCTTGA
    KLF9 Expression
    About this image


    KLF9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 4 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Uncategorized (Uncategorized)    fully expand to see all 3 entries
             PureStem Progenitor W10
     
     Ovary (Reproductive System)
             Secondary follicles
     
     Inner Cell Mass (Early Embryonic Tissues)
             Blimp1- mVenus and stella-ECFP genetically modified stem cells
     
     Epiblast (Early Embryonic Tissues)
             Epiblast Cells Epiblast

    See KLF9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KLF9

    SOURCE GeneReport for Unigene cluster: Hs.150557
        SABiosciences Custom PCR Arrays for KLF9
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLF9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for KLF9 gene from 5/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Klf91 , 5 Kruppel-like factor 91, 5 94.13(n)1
    96.72(a)1
      19 (17.90 cM)5
    166011  NM_010638.41  NP_034768.21 
     231412265 
    chicken
    (Gallus gallus)
    Aves KLF91 Kruppel-like factor 9 74.17(n)
    78.79(a)
      770238  XM_003643019.1  XP_003643067.1 
    lizard
    (Anolis carolinensis)
    Reptilia KLF96
    Uncharacterized protein
    53(a)
    1 ↔ 1
    2(49095337-49123764)
    African clawed frog
    (Xenopus laevis)
    Amphibia bteb1-A2 basic transcription element binding protein 1 77.8(n)    U35408.1 
    zebrafish
    (Danio rerio)
    Actinopterygii klf96
    Kruppel-like factor 9
    42(a)
    1 ↔ 1
    5(27719779-27722714)


    ENSEMBL Gene Tree for KLF9 (if available)
    TreeFam Gene Tree for KLF9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KLF9 gene
    KLF12  SP82  KLF172  KLF52  KLF142  SP62  KLF152  KLF22  
    KLF72  KLF82  KLF132  SP42  KLF112  SP32  SP52  KLF62  
    SP22  KLF102  KLF42  SP12  KLF162  KLF122  KLF32  SP72  
    SP92  
    18/32 SIMAP similar genes for KLF9 using alignment to 2 protein entries:     KLF9_HUMAN (see all proteins) (see all similar genes):
    KLF13    SP5    DKFZp686O1631    SP3    KLF11    KLF7
    TIEG2    KLF2    ZNF860    KLF1    KLF4    SP4
    KLF8    SP2    ZNF76    SP7    KLF17    SP1

    KLF9 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/640 SNPs in KLF9 are shown (see all 640)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs343771211,2
    C--72999061(+) AATCT-/CA    
       
    /CACA
    CACAC
    1 -- ds50010--------
    rs590864511,2
    C--72999087(+) CACAC-/AC    
       
    /ACAC
    TTTGA
    1 -- ds50011NA 2
    rs1133829221,2
    F--72999150(+) ACTTGC/TGTGTT 1 -- ds50011Minor allele frequency- T:0.50CSA 2
    rs1815378681,2
    --72999418(+) ATCTTC/TGCACT 1 -- ds50010--------
    rs1870263051,2
    --72999647(+) ACTAAC/TACTGT 1 -- ut310--------
    rs794064461,2
    F--72999779(+) AACTGA/GCAAAC 1 -- ut310--------
    rs1911142551,2
    --72999785(+) CAAACG/TAATCA 1 -- ut310--------
    rs1491332891,2
    C--72999832(+) GAGAAA/GCATGA 1 -- ut310--------
    rs1833805101,2
    --73000027(+) AAATTC/TAGTTT 1 -- ut310--------
    rs559772691,2
    C,F--73000156(+) AGTCCT/CATTTG 1 -- ut313Minor allele frequency- C:0.09WA 122

    HapMap Linkage Disequilibrium report for KLF9 (72999503 - 73029573 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for KLF9:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1491500CNV Insertion17803354
    nsv428219CNV Loss18775914
    nsv831615CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for KLF9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602902    OMIM disorders: --

    13 diseases for KLF9:    About MalaCards
    otosclerosis    endometrial carcinoma    endometrial adenocarcinoma    leiomyoma
    endometriosis    cytochrome p450    glioblastoma    multiple myeloma
    myeloma    adenocarcinoma    colorectal cancer    thyroiditis
    leukemia


    KLF9 for disorders           About GeneDecksing

    2 Novoseek inferred disease relationships for KLF9 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    endometrial carcinoma 54.6 9 16384861 (2), 17717078 (1), 11476943 (1), 11751593 (1)
    immunodeficiency 10.4 4 8257632 (2), 1356762 (1), 8051167 (1)


    Export disorders for KLF9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KLF9 gene, integrated from 9 sources (see all 54):
    (articles sorted by number of sources associating them with KLF9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cell-specific translational control of transcription factor BTEB expression. The role of an upstream AUG in the 5'-untranslated region. (PubMed id 8051167)1, 2, 9 Imataka H....Hayami M. (1994)
    2. Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene. (PubMed id 1356762)1, 3, 9 Imataka H....Fujii-Kuriyama Y. (1992)
    3. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Chromosomal localization and cDNA sequence of human BTEB, a GC box binding protein. (PubMed id 8291025)1, 2 Ohe N....Fujii-Kuriyama Y. (1993)
    6. Kruppel-like factor 9 is a negative regulator of ligand-dependent estrogen receptor alpha signaling in Ishikawa endometrial adenocarcinoma cells. (PubMed id 17717078)1, 9 Velarde M.C....Simmen R.C. (2007)
    7. Progesterone receptor transactivation of the secretory leukocyte protease inhibitor gene in Ishikawa endometrial epithelial cells involves recruitment of Kruppel-like factor 9/basic transcription element binding protein-1. (PubMed id 16384861)1, 9 Velarde M.C....Simmen R.C. (2006)
    8. Activation of the human immunodeficiency virus type 1 long terminal repeat by BTEB, a GC box-binding transcription factor. (PubMed id 8257632)1, 9 Imataka H....Hayami M. (1993)
    9. Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control. (PubMed id 8269949)1, 9 Hashimoto H....Kamataki T. (1993)
    10. The evaluation of the FOXO1, KLF9 and YT521 genes expr ession in human endometrial cancer. (PubMed id 23865345)1 Korani M....Maleki J. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 687 HGNC: 1123 AceView: BTEB1 Ensembl:ENSG00000119138 euGenes: HUgn687
    ECgene: KLF9 H-InvDB: KLF9

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KLF9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KLF9 gene:
    Search GeneIP for patents involving KLF9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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