KLF9 Gene

Aliases
for KLF9 gene

Previous GC identifers: GC09M070230 GC09M072189 GC09M042839

Summaries
for KLF9 gene

Genomic Views
for KLF9 gene

RefSeq DNA sequence:

NC_000009.11  NC_018920.1  NT_008470.19  

SwitchGear Promoter luciferase reporter plasmids (see all 2): KLF9 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLF9

KLF9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M072999:  view genomic region     (about GC identifiers)

Proteins
for KLF9 gene

Explore the universe of human proteins at neXtProt for KLF9: NX_Q13886

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: KLF9 OriGene Custom Protein Services for KLF9
	GenScript Custom Purified and Recombinant Proteins Services for KLF9
	Novus Biologicals KLF9 Protein Novus Biologicals KLF9 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for KLF9

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

	EMD Millipore Mono- and Polyclonal Antibodies for the study of KLF9
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for KLF9
	GenScript Custom Superior Antibodies Services for KLF9
	Novus Biologicals KLF9 Antibodies
	Search for Antibodies for KLF9 at Abcam
	Uscn Antibodies for KLF9
	Search ThermoFisher Antibodies for KLF9

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for KLF9
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for KLF9

Protein Domains /
Families
for KLF9 gene

ProtoNet protein and cluster: Q13886

Function
for KLF9 gene

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KLF9
		8/60 QIAGEN miScript miRNA Assays for microRNAs that regulate KLF9 (see all 60):
		hsa-miR-124* hsa-miR-579 hsa-miR-549 hsa-miR-548j hsa-miR-140-5p hsa-miR-607 hsa-miR-429 hsa-let-7d
		SwitchGear 3'UTR luciferase reporter plasmid: KLF9 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KLF9 (see all 7) OriGene shRNA RFP: KLF9 OriGene siRNA: KLF9
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KLF9

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for KLF9

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KLF9 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KLF9 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: KLF9 (NM_001206)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for KLF9
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLF9

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for KLF9
		Search LifeMap BioReagents cell lines for KLF9

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLF9

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

(inferred from 1 allele) (MGI details for Klf9)

Pathways & Interactions
for KLF9 gene

	Super-pathway	contained gene-specific pathways
1	Diurnally regulated genes with circadian orthologs	Diurnally regulated genes with circadian orthologs 1.00

1 BioSystems Pathway for KLF9

Diurnally regulated genes with circadian orthologs

Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

Drugs & Compounds
for KLF9 gene

Transcripts
for KLF9 gene

Expression
for KLF9 gene

KLF9 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTCTCTTGA

Stem Cell Differentiation: 4 LifeMap Cells
	Name			Category
	PureStem™ progenitor EN27 (Embryonic Progenitor Cell)
	PureStem™ progenitor W10 (Embryonic Progenitor Cell)
	PureStem™ progenitor W8 (Embryonic Progenitor Cell)
	Secondary follicles (Primary Cell)			Ovary, Reproductive System
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KLF9 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KLF9
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KLF9
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KLF9

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLF9

Orthologs
for KLF9 gene

Paralogs
for KLF9 gene

Paralogs for KLF9 gene

KLF1²  KLF11²  KLF6²  KLF10²  KLF4²  KLF5²  KLF14²  KLF16²  

KLF2²  KLF15²  KLF12²  KLF3²  KLF7²  KLF13²  KLF8²  

18/33 SIMAP similar genes for KLF9 using alignment to 2 protein entries:     KLF9_HUMAN (see all proteins) (see all similar genes):

KLF13    SP5    DKFZp686O1631    SP3    DKFZp313F0536    KLF11

KLF7    TIEG2    KLF2    ZNF860    KLF1    SP4

KLF8    SP2    ZNF76    SP7    KLF17    SP1

KLF9 for paralogs           About GeneDecksing

Genomic Variants
for KLF9 gene

10/551 NCBI SNPs in KLF9 are shown (see all 551)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 9 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs1133829221,2		--	72999150(+)	ACTTGC/TGTGTT	1	--	ds5001		1		CSA	2
rs1815378681,2		--	72999418(+)	ATCTTC/TGCACT	1	--	ds5001		0	--	--	--	--
rs1870263051,2		--	72999647(+)	ACTAAC/TACTGT	1	--	ut31		0	--	--	--	--
rs794064461,2		--	72999779(+)	AACTGA/GCAAAC	1	--	ut31		0	--	--	--	--
rs1911142551,2		--	72999785(+)	CAAACG/TAATCA	1	--	ut31		0	--	--	--	--
rs1491332891,2		--	72999832(+)	GAGAAA/GCATGA	1	--	ut31		0	--	--	--	--
rs1833805101,2		--	73000027(+)	AAATTC/TAGTTT	1	--	ut31		0	--	--	--	--
rs559772691,2	C,F,	--	73000156(+)	AGTCCT/CATTTG	1	--	ut31		3		WA	122
rs120024741,2	C,H	--	73000781(+)	TTTTAT/GCCCAT	1	--	ut31		5		NS EA NA	426
rs736474981,2	C,	--	73000904(+)	TTGGAG/ATCAGC	1	--	ut31		2		WA	120

HapMap Linkage Disequilibrium report for KLF9 (72999503 - 73029573 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for KLF9: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KLF9

DNA2.0 Custom Variant and Variant Library Synthesis for KLF9

Disorders / Diseases
for KLF9 gene

14 diseases for KLF9

2 Novoseek disease relationships for KLF9 gene    About this table

Publications
for KLF9 gene

PubMed articles for KLF9 gene, integrated from 9 sources (see all 53): (articles sorted by number of sources associating them with KLF9)

Utopia: connect your pdf to the dynamic world of online information

1. Cell-specific translational control of transcription factor BTEB expression. The role of an upstream AUG in the 5'-untranslated region. (PubMed id 8051167)^{1, 2, 9} Imataka H....Hayami M. (1994)
2. Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene. (PubMed id 1356762)^{1, 3, 9} Imataka H....Fujii-Kuriyama Y. (1992)
3. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)^{1, 2} Humphray S.J.... Dunham I. (2004)
4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
5. Chromosomal localization and cDNA sequence of human BTEB, a GC box binding protein. (PubMed id 8291025)^{1, 2} Ohe N....Fujii-Kuriyama Y. (1993)
6. Kruppel-like factor 9 is a negative regulator of ligand-dependent estrogen receptor alpha signaling in Ishikawa endometrial adenocarcinoma cells. (PubMed id 17717078)^{1, 9} Velarde M.C....Simmen R.C. (2007)
7. Progesterone receptor transactivation of the secretory leukocyte protease inhibitor gene in Ishikawa endometrial epithelial cells involves recruitment of Kruppel-like factor 9/basic transcription element binding protein-1. (PubMed id 16384861)^{1, 9} Velarde M.C....Simmen R.C. (2006)
8. Activation of the human immunodeficiency virus type 1 long terminal repeat by BTEB, a GC box-binding transcription factor. (PubMed id 8257632)^{1, 9} Imataka H....Hayami M. (1993)
9. Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control. (PubMed id 8269949)^{1, 9} Hashimoto H....Kamataki T. (1993)
10. Kruppel-like factor 9 and progesterone receptor coregu lation of decidualizing endometrial stromal cells: implications for the pathogen esis of endometriosis. (PubMed id 22259059)¹ Pabona J.M....Simmen R.C. (2012)

External Searches for KLF9 gene

Genome Databases showing KLF9 gene

Other Databases showing KLF9 gene

Specialized Databases showing KLF9 gene

Products
for KLF9 gene