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KLF8 Gene

protein-coding   GIFtS: 53
GCID: GC0XP056275

Kruppel-Like Factor 8

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Kruppel-Like Factor 81 2     Zinc Finger Protein 7412 3
BKLF32 3 5     Basic Kruppel-Like Factor 32
ZNF7412 3 5     Krueppel-Like Factor 82
Basic Krueppel-Like Factor 32 3     

External Ids:    HGNC: 63511   Entrez Gene: 112792   Ensembl: ENSG000001023497   OMIM: 3002865   UniProtKB: O956003   

Export aliases for KLF8 gene to outside databases

Previous GC identifers: GC0XP053239 GC0XP054197 GC0XP054864 GC0XP055226 GC0XP056141


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for KLF8 Gene:
This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this
family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is
thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which
occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16.
Alternative splicing results in multiple transcript variants. (provided by RefSeq, Apr 2009)

GeneCards Summary for KLF8 Gene:
KLF8 (Kruppel-like factor 8) is a protein-coding gene. An important paralog of this gene is KLF1.

UniProtKB/Swiss-Prot: KLF8_HUMAN, O95600
Function: Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box
of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion
kinase (FAK)

Gene Wiki entry for KLF8 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_011630.15  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KLF8 gene promoter:
         AML1a   Nkx2-5   MEF-2A   POU2F1   POU2F1a   c-Myb   aMEF-2   ZID   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKLF8 promoter sequence
   Search Chromatin IP Primers for KLF8

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KLF8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.21   Ensembl cytogenetic band:  Xp11.21   HGNC cytogenetic band: Xp11.21

KLF8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLF8 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP056275:  view genomic region     (about GC identifiers)

Start:
56,258,822 bp from pter      End:
56,314,322 bp from pter
Size:
55,501 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: KLF8_HUMAN, O95600 (See protein sequence)
Recommended Name: Krueppel-like factor 8  
Size: 359 amino acids; 39314 Da
Subunit: Interacts with corepressor CtBP2. Interacts with PIAS1, PIAS2, AND PIAS4; the interaction with each
ligase sumoylates KLF8
Secondary accessions: B4DJN3 E7EQQ8 L0R3U8 L0R4U2 Q2M246 Q59GV5 Q5HYQ5 Q5JXP7 Q6MZJ7 Q9UGC4
Alternative splicing: 4 isoforms:  O95600-1   O95600-3   O95600-4   O95600-5   

Explore the universe of human proteins at neXtProt for KLF8: NX_O95600

Explore proteomics data for KLF8 at MOPED

Post-translational modifications: 

  • Sumoylation at Lys-67 represses transcriptional activity and reduces cell cycle progression into the G(1) phase.
    Has no effect on subcellular location1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KLF8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001152768.1  NP_009181.2  

    ENSEMBL proteins: 
     ENSP00000417303   ENSP00000431911   ENSP00000364063  

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    Cloud-Clone Corp. Proteins for KLF8

     
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    antibodies-online proteins for KLF8 (5 products) 

     
    antibodies-online peptides for KLF8

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type
    KLF: Kruppel-like transcription factors

    3 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry O95600

    ProtoNet protein and cluster: O95600

    UniProtKB/Swiss-Prot: KLF8_HUMAN, O95600
    Similarity: Belongs to the Sp1 C2H2-type zinc-finger protein family
    Similarity: Contains 3 C2H2-type zinc fingers


    Find genes that share domains with KLF8           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KLF8_HUMAN, O95600
    Function: Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box
    of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion
    kinase (FAK)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with KLF8           About GenesLikeMe


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Klf8):
     embryogenesis  growth/size/body  hematopoietic system  mortality/aging 

    Find genes that share phenotypes with KLF8           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for KLF8

    miRNA
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    miRTarBase miRNAs that target KLF8:
    hsa-mir-335-5p (MIRT017467)

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    Selected qRT-PCR Assays for microRNAs that regulate KLF8 (see all 35):
    hsa-miR-3607-3p hsa-let-7d hsa-miR-4328 hsa-miR-1197 hsa-miR-513a-5p hsa-miR-4272 hsa-miR-218 hsa-miR-570
    SwitchGear 3'UTR luciferase reporter plasmidKLF8 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KLF8_HUMAN, O95600: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with KLF8           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for KLF8 About    
    See pathways by source

    SuperPathContained pathways About
    1Signaling events mediated by focal adhesion kinase
    Signaling events mediated by focal adhesion kinase


    1 BioSystems Pathway for KLF8
        Signaling events mediated by focal adhesion kinase


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KLF8
    Interactions:

        GeneGlobe Interaction Network for KLF8

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for KLF8 (O956002, 3 ENSP000004173034) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CREBBPQ927933, ENSP000002623674I2D: score=1 STRING: ENSP00000262367
    CTBP2P565453, ENSP000003118254I2D: score=2 STRING: ENSP00000311825
    EP300Q094723, ENSP000002632534I2D: score=1 STRING: ENSP00000263253
    KAT2BQ928313, ENSP000002637544I2D: score=1 STRING: ENSP00000263754
    PARP1P098743, ENSP000003557594I2D: score=1 STRING: ENSP00000355759
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with KLF8           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KLF8

    1 Novoseek inferred chemical compound relationship for KLF8 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    zinc 30.6 4 10756197 (2), 15684403 (1)



    Find genes that share compounds with KLF8           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KLF8 gene (2 alternative transcripts): 
    NM_001159296.1  NM_007250.4  

    Unigene Cluster for KLF8:

    Kruppel-like factor 8
    Hs.646614  [show with all ESTs]
    Unigene Representative Sequence: AB209004
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000476898 ENST00000462627(uc010nkg.2 uc004dur.3 uc010nkh.3)
    ENST00000468660 ENST00000358094 ENST00000374928(uc011mop.2)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate KLF8 (see all 35):
    hsa-miR-3607-3p hsa-let-7d hsa-miR-4328 hsa-miR-1197 hsa-miR-513a-5p hsa-miR-4272 hsa-miR-218 hsa-miR-570
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    Additional mRNA sequence: 

    AB209004.1 AF069138.1 AK054627.1 AK296156.1 BC031355.1 BC063276.1 BC105130.1 BC112109.1 
    HF546207.1 HF546208.1 HF546209.1 

    7 DOTS entries:

    DT.70101224  DT.100737358  DT.40259325  DT.101980821  DT.95362839  DT.121291247  DT.95349421 

    Selected AceView cDNA sequences (see all 76):

    AI377675 CD369012 BG696055 BQ026856 T31937 T17330 BC031355 BX474198 
    CD368990 BF434892 AA906449 AI393750 T32014 AA400245 BX503897 H68129 
    T17331 BG986595 BQ948858 BF445320 AA419465 BX098438 AW013859 AA336659 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for KLF8    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8
    SP1:              -                                                                     
    SP2:                                                              -                     
    SP3:                                                                                    
    SP4:                                                                                    


    ECgene alternative splicing isoforms for KLF8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KLF8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    KLF8 Expression
    About this image


    KLF8 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     NULL (Uncategorized)
             Definitive endoderm-like cells
    KLF8 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KLF8 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.646614

    UniProtKB/Swiss-Prot: KLF8_HUMAN, O95600
    Tissue specificity: Ubiquitous

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for KLF8 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Klf81 , 5 Kruppel-like factor 81, 5 85.54(n)1
    82.82(a)1
      X (68.46 cM)5
    2456711  NM_173780.41  NP_776141.11 
     1532374665 
    lizard
    (Anolis carolinensis)
    Reptilia KLF86
    Kruppel-like factor 8
    58(a)
    1 ↔ 1
    GL343577.1(275613-301626)
    African clawed frog
    (Xenopus laevis)
    Amphibia ap-2rep2 AP-2 repressor 73.49(n)    AB106877.1 
    zebrafish
    (Danio rerio)
    Actinopterygii klf122 Kruppel-like factor 12 78.68(n)   117603  AF392993.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG120293   -- 75(a)
    (best of 2)
        --


    ENSEMBL Gene Tree for KLF8 (if available)
    TreeFam Gene Tree for KLF8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KLF8 gene
    KLF12  SP82  KLF172  KLF52  KLF142  SP62  KLF152  KLF22  
    KLF72  KLF132  SP42  KLF112  SP32  SP52  KLF62  SP22  
    KLF102  KLF42  SP12  KLF162  KLF122  KLF32  KLF92  SP72  
    SP92  
    18 SIMAP similar genes for KLF8 using alignment to 2 protein entries:     KLF8_HUMAN (see all proteins):
    KLF6    ZNF78L1    ZNF    KLF13    DKFZp434J0650    ZNF702P
    KLF12    KLF4    KLF9    ZNF697    KLF7    ZFS-2
    ZNF808    ZNF72    KLF16    ZNF600    KLF3    ZNF844

    Find genes that share paralogs with KLF8           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for KLF8
    PGOHUM00000249125 PGOHUM00000249476


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KLF8 (see all 647)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs589596951,2
    C--56261866(+) TTTTT-/T/TT  
            
    GACAC
    2 -- int10--------
    rs107071121,2
    C--56267430(+) aaatt-/Aaaaaa 2 -- int1 trp31Minor allele frequency- A:0.00CSA 2
    rs1838075821,2
    --56274486(+) ACAAAC/TACATA 2 -- us2k10--------
    rs1886301311,2
    --56274598(+) ATACAC/TAAGAG 2 -- us2k10--------
    rs128594301,2
    C,H--56274621(+) gtttaG/Ctacat 2 -- us2k14Minor allele frequency- C:0.00NS EA 418
    rs732065791,2
    C--56274669(+) ATATAA/GCTTGG 2 -- us2k10--------
    rs607136421,2
    C--56274680(+) CATCCC/AAGTTA 2 -- us2k11Minor allele frequency- A:0.50WA 2
    rs1495786011,2
    C--56274815(+) CCTGAA/GGAAAT 2 -- us2k10--------
    rs1807189901,2
    --56274885(+) GGAAGA/GACATG 2 -- us2k10--------
    rs1442892951,2
    C--56274903(+) AAAAAA/TGGTGG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for KLF8 (56258822 - 56314322 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for KLF8: --
    Human Gene Mutation Database (HGMD): KLF8
    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300286    OMIM disorders: --


    Find genes that share disorders with KLF8           About GenesLikeMe

    Genetic Association Database (GAD): KLF8
    Human Genome Epidemiology (HuGE) Navigator: KLF8 (1 document)

    Export disorders for KLF8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KLF8 gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with KLF8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human Kruppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription. (PubMed id 10756197)1, 2, 9 van Vliet J.... Crossley M. (Nucleic Acids Res. 2000)
    2. Shaking the family tree: Identification of novel and biologically active alternatively spliced isoforms across the KLF family of transcription factors. (PubMed id 23134681)1, 2 Camacho-Vanegas O.... Martignetti J.A. (FASEB J. 2013)
    3. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    4. Single nucleotide polymorphisms in the gene encoding KrA1ppel-like factor 7 are associated with type 2 diabetes. (PubMed id 15937668)1, 4 Kanazawa A....Maeda S. (Diabetologia 2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progression. (PubMed id 12820964)1, 2 Zhao J.... Guan J.L. (Mol. Cell 2003)
    7. Abnormal expression of the KLF8 (ZNF741) gene in a female patient with an X;autosome translocation t(X;21)(p11.2;q22.3) and non-syndromic mental retardation. (PubMed id 11836360)1, 9 Lossi A.M....Villard L. (J. Med. Genet. 2002)
    8. KLF8 transcription factor participates in oncogenic transformation. (PubMed id 16832343)1, 9 Wang X. and Zhao J. (Oncogene 2007)
    9. Transformation of human ovarian surface epithelial cells by KrA1ppel-like factor 8. (PubMed id 23222713)1 Lu H....Zhao J. (Oncogene 2014)
    10. KrA1ppel-like factor 8 is a novel androgen receptor co-activator in human prostate cancer. (PubMed id 23023312)1 He H.J....Su Y. (Acta Pharmacol. Sin. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 11279 HGNC: 6351 AceView: KLF8 Ensembl:ENSG00000102349 euGenes: HUgn11279
    ECgene: KLF8 H-InvDB: KLF8

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KLF8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KLF8 gene:
    Search GeneIP for patents involving KLF8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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