Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KLF17 Gene

protein-coding   GIFtS: 47
GCID: GC01P044584

Kruppel-Like Factor 17

(Previous name: zinc finger protein 393)
(Previous symbol: ZNF393)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Kruppel-Like Factor 171 2
ZNF3931 2 3 5
Zinc Finger Protein 3931 2 3
Zfp3932
Krueppel-Like Factor 172
Novel Zinc-Finger Protein2

External Ids:    HGNC: 188301   Entrez Gene: 1282092   Ensembl: ENSG000001718727   OMIM: 6096025   UniProtKB: Q5JT823   

Export aliases for KLF17 gene to outside databases

Previous GC identifers: GC01P044357 GC01P042699


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for KLF17 Gene: 
KLF17 (Kruppel-like factor 17) is a protein-coding gene. Diseases associated with KLF17 include lung adenocarcinoma, and breast cancer. GO annotations related to this gene include transcription regulatory region DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is KLF1.

UniProtKB/Swiss-Prot: KLF17_HUMAN, Q5JT82
Function: Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts
as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds
the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its
expression. May be a germ cell-specific transcription factor that plays important roles in spermatid
differentiation and oocyte development (By similarity)

Gene Wiki entry for KLF17 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KLF17 gene promoter:
         Bach1   ISGF-3   FOXO3   FOXD3   FOXO3b   AREB6   FAC1   FOXO4   COMP1   FOXO3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): KLF17 promoter sequence
   Search SABiosciences Chromatin IP Primers for KLF17

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLF17


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.1   Ensembl cytogenetic band:  1p34.1   HGNC cytogenetic band: 1p34.1

KLF17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLF17 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P044584:  view genomic region     (about GC identifiers)

Start:
44,584,522 bp from pter      End:
44,600,812 bp from pter
Size:
16,291 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KLF17_HUMAN, Q5JT82 (See protein sequence)
Recommended Name: Krueppel-like factor 17  
Size: 389 amino acids; 42577 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: Q86VQ7 Q8N805

Explore the universe of human proteins at neXtProt for KLF17: NX_Q5JT82

Explore proteomics data for KLF17 at MOPED 

KLF17 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

KLF17 Protein Expression

REFSEQ proteins: NP_775755.3  
ENSEMBL proteins: 
 ENSP00000361373  

Human Recombinant Protein Products for KLF17: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate for KLF17
OriGene Custom MassSpec 
OriGene Custom Protein Services for KLF17
GenScript Custom Purified and Recombinant Proteins Services for KLF17
Novus Biologicals KLF17 Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for KLF17 

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

KLF17 for ontologies           About GeneDecksing



KLF17 Antibody Products: 
Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
R&D Systems Antibodies for KLF17
Browse OriGene Antibodies
OriGene Custom Antibody Services for KLF17
GenScript Custom Superior Antibodies Services for KLF17
Novus Biologicals KLF17 Antibodies
Abcam antibodies for KLF17
Cloud-Clone Corp. Antibodies for KLF17 
ThermoFisher Antibodies for KLF17
LSBio Antibodies in human, mouse, rat for KLF17 

Assay Products for KLF17: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for KLF17
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for KLF17
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for KLF17 
Cloud-Clone Corp. CLIAs for KLF17


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
ZNF: Zinc fingers, C2H2-type
KLF: Kruppel-like transcription factors

3 InterPro protein domains:
 IPR015880 Znf_C2H2-like
 IPR013087 Znf_C2H2/integrase_DNA-bd
 IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q5JT82

ProtoNet protein and cluster: Q5JT82

UniProtKB/Swiss-Prot: KLF17_HUMAN, Q5JT82
Similarity: Belongs to the Sp1 C2H2-type zinc-finger protein family
Similarity: Contains 3 C2H2-type zinc fingers


KLF17 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: KLF17_HUMAN, Q5JT82
Function: Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts
as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds
the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its
expression. May be a germ cell-specific transcription factor that plays important roles in spermatid
differentiation and oocyte development (By similarity)

     Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003700sequence-specific DNA binding transcription factor activity ISS--
GO:0008270zinc ion binding ----
GO:0044212transcription regulatory region DNA binding ISS--
GO:0046872metal ion binding IEA--
     
KLF17 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for KLF17 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KLF17

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KLF17 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KLF17 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KLF17
2 QIAGEN miScript miRNA Assays for microRNAs that regulate KLF17:
hsa-miR-2355-5p hsa-miR-1264
SwitchGear 3'UTR luciferase reporter plasmidKLF17 3' UTR sequence
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for KLF17
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KLF17

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for KLF17
Sirion Biotech Customized adenovirus for overexpression of KLF17

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene clones in human, mouse for KLF17 (see all 6)
OriGene ORF clones in mouse, rat for KLF17
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: KLF17 (NM_173484)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for KLF17
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLF17
Sirion Biotech Customized lentivirus for stable overexpression of KLF17 
                     Customized lentivirus expression plasmids for stable overexpression of KLF17 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for KLF17
Search LifeMap BioReagents cell lines for KLF17
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLF17


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KLF17

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006351transcription, DNA-dependent IEA--
GO:0006357regulation of transcription from RNA polymerase II promoter ISS--
GO:0007276gamete generation IEA--

KLF17 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for KLF17

Search CenterWatch for drugs/clinical trials and news about KLF17

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for KLF17 gene: 
NM_173484.3  

Unigene Cluster for KLF17:

Kruppel-like factor 17
Hs.567674  [show with all ESTs]
Unigene Representative Sequence: BC049844
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000372299(uc009vxf.1 uc001clp.3) ENST00000476802
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KLF17
2 QIAGEN miScript miRNA Assays for microRNAs that regulate KLF17:
hsa-miR-2355-5p hsa-miR-1264
SwitchGear 3'UTR luciferase reporter plasmidKLF17 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for KLF17
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KLF17
Clone
Products:
     
OriGene clones in human, mouse for KLF17 (see all 6)
OriGene ORF clones in mouse, rat for KLF17
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: KLF17 (NM_173484)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for KLF17
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLF17
Sirion Biotech Customized lentivirus for stable overexpression of KLF17 
                     Customized lentivirus expression plasmids for stable overexpression of KLF17 
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for KLF17
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KLF17
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KLF17
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KLF17

Additional mRNA sequence: 

AK097479.1 AK308458.1 BC035408.1 BC049844.1 

1 DOTS entry:

DT.100014537 

9 AceView cDNA sequences:

NM_173484 BC049844 BI825370 BI825843 BI460100 CA310442 AK097479 BC035408 
BI827544 

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for KLF17    About this scheme

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6
SP1:              -                                       
SP2:              -           -                           
SP3:                                                      


ECgene alternative splicing isoforms for KLF17

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

KLF17 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TTAGGAAGGT
KLF17 Expression
About this image


See KLF17 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KLF17

SOURCE GeneReport for Unigene cluster: Hs.567674
    SABiosciences Custom PCR Arrays for KLF17
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for KLF17
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KLF17
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KLF17
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KLF17
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLF17

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for KLF17 gene from 2/8 species (see all 8)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Klf171 , 5 Kruppel-like factor 171, 5 65.97(n)1
50(a)1
  4 (53.46 cM)5
757531  NM_029416.21  NP_083692.21 
 1177578365 
fruit fly
(Drosophila melanogaster)
Insecta btd6
CG30656
--
9(a)
13(a)
1 ↔ many
1 ↔ many
X(9588221-9591606)
2R(19857830-19859756)


ENSEMBL Gene Tree for KLF17 (if available)
TreeFam Gene Tree for KLF17 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for KLF17 gene
KLF12  SP82  KLF52  KLF142  SP62  KLF152  KLF22  KLF72  
KLF82  KLF132  SP42  KLF112  SP32  SP52  KLF62  SP22  
KLF102  KLF42  SP12  KLF162  KLF122  KLF32  KLF92  SP92  
SP72  
18/29 SIMAP similar genes for KLF17 using alignment to 1 protein entry:     KLF17_HUMAN(see all similar genes):
DKFZp686N0199    ZNF78L1    kr-znf3    smap-7    zf30    DKFZp686M04222
DKFZp686O1631    ZNF702P    ZNF    ZFS-6    ZNF323    ZNF833P
KLF9    DKFZp434J0650    HZF40    ZFS-2    ZFS-5    ZNF72

KLF17 for paralogs           About GeneDecksing


2 Pseudogenes.org Pseudogenes for KLF17
PGOHUM00000239489 PGOHUM00000245855


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/519 SNPs in KLF17 are shown (see all 519)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1432241051,2
Cuntested144595487(+) CTGGCC/TTCTCG 2 L F mis11Minor allele frequency- T:0.00NA 4546
rs758999801,2
C--44582609(+) AGTTGC/ACTCCA 1 -- us2k12Minor allele frequency- A:0.04NA 122
rs1836271841,2
--44582617(+) CCAAAA/TCTGCT 1 -- us2k10--------
rs1399097081,2
C--44582641(+) TTCCAC/TATACC 1 -- us2k10--------
rs1881168511,2
--44582655(+) TGGCAC/TGATCA 1 -- us2k10--------
rs1928711431,2
--44582726(+) CTACCA/CCCTTC 1 -- us2k10--------
rs1828576241,2
--44582727(+) TACCCC/GCTTCT 1 -- us2k10--------
rs1868595501,2
--44582766(+) TTTTTC/TTTTAG 1 -- us2k10--------
rs1432972451,2
--44582827(+) GGTGTA/GGTAAT 1 -- us2k10--------
rs1912710071,2
--44582890(+) CAGTTC/TATCCC 1 -- us2k10--------

HapMap Linkage Disequilibrium report for KLF17 (44584522 - 44600812 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for KLF17:    About this table     
Variant IDTypeSubtypePubMed ID
nsv829704CNV Loss17160897

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing KLF17
DNA2.0 Custom Variant and Variant Library Synthesis for KLF17

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 609602    OMIM disorders: --

3 diseases for KLF17:    About MalaCards
lung adenocarcinoma    breast cancer    adenocarcinoma


KLF17 for disorders           About GeneDecksing


Export disorders for KLF17 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for KLF17 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with KLF17)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Human KLF17 is a new member of the Sp/KLF family of transcription factors. (PubMed id 16460907)1, 2, 3, 9 van Vliet J....Crossley M. (2006)
  2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  5. Down-regulated KLF17 expression is associated with tum or invasion and poor prognosis in hepatocellular carcinoma. (PubMed id 23325444)1 Liu F.Y....Liu M. (2013)
  6. Reduced expression of Kruppel-like factor 17 is relate d to tumor growth and poor prognosis in lung adenocarcinoma. (PubMed id 22240024)1 Cai X.D....Han A.J. (2012)
  7. KLF17 is a negative regulator of epithelial-mesenchym al transition and metastasis in breast cancer. (PubMed id 19801974)1 Gumireddy K....Huang Q. (2009)
  8. Transcriptional regulation of metastatic [Id]entity b y KLF17. (PubMed id 19951400)1 Iwanicki M.P. and Brugge J.S. (2009)
  9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
  10. Identification of Zfp393, a germ cell-specific gene encoding a novel zinc finger protein. (PubMed id 12351194)1 Yan W....Matzuk M.M. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 128209 HGNC: 18830 AceView: FLJ40160 Ensembl:ENSG00000171872 euGenes: HUgn128209
ECgene: KLF17 H-InvDB: KLF17

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for KLF17 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for KLF17 gene:
Search GeneIP for patents involving KLF17

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

 
 EMD Millipore Custom Antibody & Bulk Services
 EMD Millipore Preclinical / Clinical Development Services
 EMD Millipore Immunoassay Services
 EMD Millipore Target Screening & Profiling Services

  
 Antibodies for KLF17 (KLF17)   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
 Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
 Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for KLF17  
 Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for KLF17  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for KLF17  
 OriGene qSTAR qPCR primer pairs in human, mouse for KLF17   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for KLF17   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for KLF17   OriGene Custom Protein Services for KLF17  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KLF17
 QIAGEN SeqTarget long-range PCR primers for resequencing KLF17
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLF17
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KLF17
 QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KLF17
 QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KLF17
 GenScript Custom Purified and Recombinant Proteins Services for KLF17 GenScript cDNA clones with any tag delivered in your preferred vector for KLF17
 GenScript Custom Assay Services for KLF17 GenScript Custom Superior Antibodies Services for KLF17
 GenScript Custom overexpressing Cell Line Services for KLF17 CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Regulatory tfbs in KLF17 promoter
 Search Chromatin IP Primers for KLF17
 RT2 qPCR Primer Assay in human, mouse, rat KLF17
 Search GNC Networks for KLF17
 SABiosciences Custom PCR Arrays for KLF17
 Search Tocris compounds for KLF17
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 KLF17 antibodies
 KLF17 lysates
 Antibodies for KLF17
 See all of Abcam's Antibodies, Kits and Proteins for KLF17
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins




 Proteins for KLF17
 Antibodies for KLF17
 ELISAs for KLF17
 CLIAs for KLF17
 Search LifeMap BioReagents cell lines for KLF17
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLF17
 SwitchGear 3'UTR luciferase reporter plasmids for KLF17
 SwitchGear Promoter luciferase reporter plasmids for KLF17
 ThermoFisher Antibodies for KLF17
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KLF17
 inGenious Targeting Laboratory - Custom generated mouse model solutions for KLF17
 inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for KLF17
Customized:
 lentivirus for stable overexpression of KLF17
 lentivirus expression plasmids for stable overexpression of KLF17
 adenovirus for overexpression of KLF17
 LSBio Antibodies in human, mouse, rat for KLF17
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
       
GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

View Random Gene

Category
(GIFtS: 73)
transforming growth factor, beta 1
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      KLF17 gene at Home site.
hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4