Aliases for KLF17 Gene
External Ids for KLF17 Gene
Previous HGNC Symbols for KLF17 Gene
Previous GeneCards Identifiers for KLF17 Gene
GeneCards Summary for KLF17 Gene
KLF17 (Kruppel-Like Factor 17) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription regulatory region DNA binding. An important paralog of this gene is KLF2.
UniProtKB/Swiss-Prot for KLF17 Gene
Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5-CACCC-3 sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity).