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KLF13 Gene

protein-coding   GIFtS: 53
GCID: GC15P031619

Kruppel-Like Factor 13

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Kruppel-Like Factor 131 2     BTE-Binding Protein 32 3
Basic Transcription Element-Binding Protein 32 3     RANTES Factor Of Late Activated T-Lymphocytes 12 3
Novel Sp1-Like Zinc Finger Transcription Factor 12 3     FKLF22 5
Transcription Factor BTEB32 3     RFLAT12 5
Transcription Factor NSLP12 3     Basic Transcription Element Binding Protein 32
BTEB32 3     Krueppel-Like Factor 132
NSLP12 3     RANTES Factor Of Late Activated T Lymphocytes-12
RFLAT-12 3     Sp1 Like Zinc Finger Transcription Factor2

External Ids:    HGNC: 136721   Entrez Gene: 516212   Ensembl: ENSG000001699267   OMIM: 6053285   UniProtKB: Q9Y2Y93   
ORGUL members:         

Export aliases for KLF13 gene to outside databases

Previous GC identifers: GC15M027358 GC15P024375 GC15P029199 GC15P029335 GC15P028915 GC15P008795


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for KLF13 Gene:
KLF13 belongs to a family of transcription factors that contain 3 classical zinc finger DNA-binding domains
consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These
transcription factors bind to GC-rich sequences and related GT and CACCC boxes (Scohy et al., 2000 (PubMed
11087666)).(supplied by OMIM, Mar 2008)

GeneCards Summary for KLF13 Gene:
KLF13 (Kruppel-like factor 13) is a protein-coding gene. An important paralog of this gene is KLF1.

UniProtKB/Swiss-Prot: KLF13_HUMAN, Q9Y2Y9
Function: Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the
activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates
RANTES expression in T-cells

Gene Wiki entry for KLF13 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000015.9  NC_018926.2  NT_010194.18  NT_187660.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the KLF13 gene promoter:
         Sp1   p53   STAT3   Nkx2-5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKLF13 promoter sequence
   Search Chromatin IP Primers for KLF13

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KLF13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q12   Ensembl cytogenetic band:  15q13.3   HGNC cytogenetic band: 15q13.3

KLF13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLF13 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P031619:  view genomic region     (about GC identifiers)

Start:
31,619,058 bp from pter      End:
31,727,868 bp from pter
Size:
108,811 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: KLF13_HUMAN, Q9Y2Y9 (See protein sequence)
Recommended Name: Krueppel-like factor 13  
Size: 288 amino acids; 31180 Da
Secondary accessions: Q9Y356

Explore the universe of human proteins at neXtProt for KLF13: NX_Q9Y2Y9

Explore proteomics data for KLF13 at MOPED

Post-translational modifications: 

  • Phosphorylated1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KLF13 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057079.2  
    ENSEMBL proteins: 
     ENSP00000302456   ENSP00000452609   ENSP00000452867  

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    antibodies-online proteins for KLF13 (2 products) 

     
    antibodies-online peptides for KLF13

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type
    KLF: Kruppel-like transcription factors

    3 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q9Y2Y9

    ProtoNet protein and cluster: Q9Y2Y9

    UniProtKB/Swiss-Prot: KLF13_HUMAN, Q9Y2Y9
    Domain: The Ala/Pro-rich domain may contain discrete activation and repression subdomains and also can mediate
    protein-protein interactions
    Similarity: Belongs to the Sp1 C2H2-type zinc-finger protein family
    Similarity: Contains 3 C2H2-type zinc fingers


    Find genes that share domains with KLF13           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KLF13_HUMAN, Q9Y2Y9
    Function: Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the
    activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates
    RANTES expression in T-cells

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0005515protein binding IPI17053787
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with KLF13           About GenesLikeMe


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Klf13):
     cellular  hematopoietic system  immune system 

    Find genes that share phenotypes with KLF13           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for KLF13: Klf13tm1Kren Klf13tm1Coll

       genOway: Develop your customized and physiologically relevant rodent model for KLF13

    miRNA
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    miRTarBase miRNAs that target KLF13:
    hsa-mir-372-3p (MIRT000060), hsa-mir-302d-3p (MIRT000094), hsa-mir-335-5p (MIRT018161), hsa-mir-125a-5p (MIRT005339), hsa-mir-31-5p (MIRT004972), hsa-mir-125b-5p (MIRT003421), hsa-mir-98-5p (MIRT005676)

    Block miRNA regulation of human, mouse, rat KLF13 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KLF13 (see all 146):
    hsa-miR-640 hsa-miR-361-5p hsa-miR-199a-3p hsa-miR-1245 hsa-miR-519a hsa-miR-3921 hsa-miR-759 hsa-miR-3622b-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KLF13_HUMAN, Q9Y2Y9: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with KLF13           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KLF13
    Interactions:

        GeneGlobe Interaction Network for KLF13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for KLF13 (Q9Y2Y91, 2, 3 ENSP000003024564) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GATA4P436941, 2, 3, ENSP000003344584EBI-1255893,EBI-7049352 MINT-3379492 MINT-3379533 MINT-3379514 I2D: score=1 STRING: ENSP00000334458
    GATA6Q929082, 3, ENSP000002692164MINT-3379559 I2D: score=1 STRING: ENSP00000269216
    PRPF4BQ135231, 3, ENSP000003371944EBI-1255893,EBI-395940 I2D: score=2 STRING: ENSP00000337194
    KAT2BQ928313, ENSP000002637544I2D: score=2 STRING: ENSP00000263754
    CREBBPQ927933, ENSP000002623674I2D: score=2 STRING: ENSP00000262367
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006357regulation of transcription from RNA polymerase II promoter ----
    GO:0006366transcription from RNA polymerase II promoter TAS10023774
    GO:0008285negative regulation of cell proliferation IEA--
    GO:0045647negative regulation of erythrocyte differentiation IEA--
    GO:0045944positive regulation of transcription from RNA polymerase II promoter IEA--

    Find genes that share ontologies with KLF13           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KLF13

    4 Novoseek inferred chemical compound relationships for KLF13 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    rantes 60.9 5 12050170 (1), 17322928 (1), 17513757 (1)
    zinc 41.7 2 18056793 (1), 10828046 (1)
    proline 38.4 1 11087666 (1)
    alanine 23.3 1 11087666 (1)



    Find genes that share compounds with KLF13           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KLF13 gene: 
    NM_015995.2  

    Unigene Cluster for KLF13:

    Kruppel-like factor 13
    Hs.525752  [show with all ESTs]
    Unigene Representative Sequence: NM_015995
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000307145(uc001zfo.3) ENST00000558921 ENST00000560473 ENST00000558844
    ENST00000558673 ENST00000500533(uc001zfp.1) ENST00000558225
    miRNA
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    hsa-miR-640 hsa-miR-361-5p hsa-miR-199a-3p hsa-miR-1245 hsa-miR-519a hsa-miR-3921 hsa-miR-759 hsa-miR-3622b-3p
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      QuantiFast Probe-based Assays in human, mouse, rat KLF13

    Additional mRNA sequence: 

    AF132599.1 AF150628.1 AL390127.1 BC010438.1 BC012741.2 BC012782.2 BC013946.2 BC035503.2 
    BC064552.1 

    3 DOTS entries:

    DT.448648  DT.75180354  DT.92432531 

    Selected AceView cDNA sequences (see all 265):

    AI523638 AW192131 AI380493 AA788627 AW470389 BU186560 AI358221 BU429342 
    AW771538 CA435184 BM741233 BE219023 BM765501 BM772456 BQ001348 BM771648 
    BE466788 BX474032 AA614816 AI634552 AW590102 BM782070 BF739932 CA437442 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KLF13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTAGTGACG
    KLF13 Expression
    About this image


    KLF13 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Midbrain tegmentum
     
     Inner Cell Mass (Early Embryonic Tissues)
             hIPS1
     
     Thymus (Hematopoietic System)
    KLF13 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KLF13 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.525752

    UniProtKB/Swiss-Prot: KLF13_HUMAN, Q9Y2Y9
    Tissue specificity: Ubiquitous

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for KLF13 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Klf131 , 5 Kruppel-like factor 131, 5 91.52(n)1
    94.7(a)1
      7 (34.58 cM)5
    507941  NM_021366.31  NP_067341.21 
     638863505 
    chicken
    (Gallus gallus)
    Aves KLF131 Kruppel-like factor 13 60.36(n)
    63.27(a)
      427493  XM_425065.4  XP_425065.1 
    lizard
    (Anolis carolinensis)
    Reptilia KLF136
    Kruppel-like factor 13
    85(a)
    1 ↔ 1
    GL343428.1(156120-172896)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ033532.12   -- 73.82(n)    BJ033532.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi22b082 wufi22b08 77.72(n)   333937  57049513 


    ENSEMBL Gene Tree for KLF13 (if available)
    TreeFam Gene Tree for KLF13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KLF13 gene
    KLF12  SP82  KLF172  KLF52  KLF142  SP62  KLF152  KLF22  
    KLF72  KLF82  SP42  KLF112  SP32  SP52  KLF62  SP22  
    KLF102  KLF42  SP12  KLF162  KLF122  KLF32  KLF92  SP72  
    SP92  
    Selected SIMAP similar genes for KLF13 using alignment to 3 protein entries:     KLF13_HUMAN (see all proteins) (see all similar genes):
    DKFZp686O1631    KLF7    SP3    KLF9    KLF1    DKFZp686N0199
    ZNF500    WT1    ZNF18    HKR1    KLF8    ZNF19
    ZNF83    ZNF263    KLF4    KLF16    kr-znf3    A-328A3.4

    Find genes that share paralogs with KLF13           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KLF13 (see all 1027)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1462546021,2
    --31617259(+) AAGAAA/GTGACT 1 -- us2k10--------
    rs1391532591,2
    --31617288(+) GAATAA/GAGGAA 1 -- us2k10--------
    rs1897758651,2
    --31617333(+) TCTTAC/TTAAAT 1 -- us2k10--------
    rs1817549591,2
    --31617370(+) AACACC/GATTAC 1 -- us2k10--------
    rs760209961,2
    C,F--31617405(+) AAAGGG/AACCAG 1 -- us2k11Minor allele frequency- A:0.05WA 118
    rs1874101651,2
    --31617465(+) GAGACA/CGCATT 1 -- us2k10--------
    rs38035531,2
    C,F,H--31617476(+) TCAGGG/ATTTTA 1 -- us2k15Minor allele frequency- A:0.01NS EA NA 418
    rs1921281471,2
    --31617786(+) CAATGC/TAACGG 1 -- us2k10--------
    rs64936041,2
    C,F,H--31617788(+) ATGCAC/ACGGGG 1 -- us2k120Minor allele frequency- A:0.36NS EA WA NA 2344
    rs80412031,2
    C--31617877(+) GCCTGG/CAGAAT 1 -- us2k11Minor allele frequency- C:0.00NA 2

    HapMap Linkage Disequilibrium report for KLF13 (31619058 - 31727868 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for KLF13 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv516681CNV Loss19592680
    nsv456747CNV Loss19166990
    nsv903840CNV Loss21882294
    nsv456748CNV Loss19166990
    esv29856CNV Loss19812545
    nsv903838CNV Loss21882294
    esv34100CNV Loss18971310
    dgv2308n71CNV Loss21882294
    nsv827280CNV Gain20364138
    nsv903831CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605328    OMIM disorders: --


    Find genes that share disorders with KLF13           About GenesLikeMe

    Genetic Association Database (GAD): KLF13
    Human Genome Epidemiology (HuGE) Navigator: KLF13 (1 document)

    Export disorders for KLF13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KLF13 gene, integrated from 10 sources (see all 35):
    (articles sorted by number of sources associating them with KLF13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Sp1 and its likes: biochemical and functional predictions for a growing family of zinc finger transcription factors. (PubMed id 10415854)1, 2, 3 Cook T.... Urrutia R. (Ann. N. Y. Acad. Sci. 1999)
    2. RFLAT-1: a new zinc finger transcription factor that activates RANTES gene expression in T lymphocytes. (PubMed id 10023774)1, 2, 3 Song A.... Krensky A.M. (Immunity 1999)
    3. Single nucleotide polymorphisms in the gene encoding KrA1ppel-like factor 7 are associated with type 2 diabetes. (PubMed id 15937668)1, 4 Kanazawa A....Maeda S. (Diabetologia 2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The Sp1-like protein BTEB3 inhibits transcription via the basic transcription element box by interacting with mSin3A and HDAC-1 co- repressors and competing with Sp1. (PubMed id 11477107)1, 2 Kaczynski J.... Urrutia R. (J. Biol. Chem. 2001)
    6. FKLF-2: a novel KrA1ppel-like transcriptional factor that activates globin and other erythroid lineage genes. (PubMed id 10828046)1, 9 Asano H....Stamatoyannopoulos G. (Blood 2000)
    7. Interaction of PRP4 with Kruppel-like factor 13 regulates CCL5 transcription. (PubMed id 17513757)1, 9 Huang B....Krensky A.M. (J. Immunol. 2007)
    8. A novel functional interaction between the Sp1-like protein KLF13 and SREBP-Sp1 activation complex underlies regulation of low density lipoprotein receptor promoter function. (PubMed id 16303770)1, 9 Natesampillai S....Veldhuis J.D. (J. Biol. Chem. 2006)
    9. Identification of KLF13 and KLF14 (SP6), novel members of the SP/XKLF transcription factor family. (PubMed id 11087666)1, 9 Scohy S.... Szpirer C. (Genomics 2000)
    10. Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells. (PubMed id 18056793)1, 9 Natesampillai S....Veldhuis J.D. (Am. J. Physiol. Endocrinol. Metab. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51621 HGNC: 13672 AceView: KLF13 Ensembl:ENSG00000169926 euGenes: HUgn51621
    ECgene: KLF13 H-InvDB: KLF13

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KLF13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KLF13 gene:
    Search GeneIP for patents involving KLF13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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