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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KLC3 Gene

protein-coding   GIFtS: 54
GCID: GC19P045851

kinesin light chain 3
 Explore 2 diseases affiliated with
KLC3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for KLC3    

Aliases
for KLC3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Kinesin Light Chain 31 2     KLC22 3
KLC2L1 2 3 5     Kinesin Light Chain 22 3
KLCt1 2     KLC2-Like1
KNS2B1 2     

External Ids:    HGNC: 207171   Entrez Gene: 1477002   Ensembl: ENSG000001048927   OMIM: 6013345   UniProtKB: Q6P5973   

Export aliases for KLC3 gene to outside databases

Previous GC identifers: GC19P050538 GC19P045847 GC19P042276


Summaries
for KLC3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for KLC3:
This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the
transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain
(KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the
rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with
structural components of sperm tails and mitochondria. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: KLC3_HUMAN, Q6P597
Function: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport

Gene Wiki entry for KLC3


Genomic Views
for KLC3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KLC3 gene promoter:
         FAC1   NRSF form 1   MyoD   NRSF form 2   Tal-1beta   ITF-2   Roaz   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: KLC3 promoter sequence
   Search SABiosciences Chromatin IP Primers for KLC3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KLC3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13   Ensembl cytogenetic band:  19q13.32   HGNC cytogenetic band: 19q13

KLC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLC3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P045851:  view genomic region     (about GC identifiers)

Start:
 45,836,692 bp from pter      End:
 45,854,778 bp from pter
Size:
 18,087 bases      Orientation:
 plus strand

Proteins
for KLC3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: KLC3_HUMAN, Q6P597 (See protein sequence)
Recommended Name: Kinesin light chain 3  
Size: 504 amino acids; 55364 Da
Subunit: Oligomer composed of two heavy chains and two light chains. Associates with microtubulin in an ATP-dependent
manner. Interacts with KIF5C and ODF1 (By similarity)
Subcellular location: Cytoplasm, cytoskeleton (Probable). Note=Elongating spermatid tail midpiece, localized in outer
dense fibers (ODFs) and associates with mitochondria (By similarity)
Secondary accessions: A0AVM3 A2RUT6 Q6GMU2 Q8NAL1 Q8WWJ9
Alternative splicing: 3 isoforms:  Q6P597-1   Q6P597-2   Q6P597-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KLC3: NX_Q6P597

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q6P597

    • KLC3 Protein expression data from MOPED and PaxDb:    About this image 
    KLC3 Protein Expression
    REFSEQ proteins: NP_803136.2  
    ENSEMBL proteins: 
     ENSP00000465950   ENSP00000375810   ENSP00000466067   ENSP00000466974   ENSP00000466168  
     ENSP00000436019  
    Reactome Protein details: Q6P597
    Human Recombinant Protein Products for KLC3: 
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    Novus Biologicals KLC3 Protein
    Novus Biologicals KLC3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for KLC3

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005871kinesin complex IEA--
    GO:0005874microtubule IEA--
    GO:0035253ciliary rootlet IEA--
    GO:0043005neuron projection IEA--

    KLC3 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for KLC3

    Protein Domains /
    Families
    for KLC3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    KLC3 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR011990 TPR-like_helical
     IPR002151 Kinesin_light
     IPR001440 TPR-1
     IPR015390 Rabaptin_Rab5-bd_dom
     IPR013026 TPR-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q6P597

    ProtoNet protein and cluster: Q6P597

    UniProtKB/Swiss-Prot: KLC3_HUMAN, Q6P597
    Domain: The heptad repeat (HR) motif is sufficient for interaction with kinesin heavy (KHL) chains and ODF1. The TPR
    region is involved in mitochondrial binding (By similarity)
    Similarity: Belongs to the kinesin light chain family
    Similarity: Contains 5 TPR repeats


    Function
    for KLC3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KLC3_HUMAN, Q6P597
    Function: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003777microtubule motor activity IEA--
    GO:0005515protein binding ----
    GO:0008017microtubule binding IEA--
    GO:0008808cardiolipin synthase activity IEA--
    GO:0019894kinesin binding IEA--
         
    KLC3 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for KLC3:
     Decreased POU5F1-GFP protein e  Increased cell number in G2M,  

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for KLC3 

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat KLC3
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    SwitchGear 3'UTR luciferase reporter plasmid: KLC3 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: KLC3
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    Gene Editing
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    In Situ Assay
    Products:       
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    Pathways & Interactions
    for KLC3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Immune System
    		Immune System1.00
    		Adaptive Immune System0.59
    2Kinesins
    		Kinesins1.00
    		Kinesins move along microtubules consuming ATP0.95
    3MHC class II antigen presentation
    		MHC class II antigen presentation1.00
    		Transport of antigen loaded MHC II molecules to surface0.59
    4Factors involved in megakaryocyte development and platelet production
    		Factors involved in megakaryocyte development and platelet production1.00
    5Platelet activation, signaling and aggregation
    		Hemostasis0.43

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/8        Reactome Pathways for KLC3 (see all 8)
        Hemostasis
    Adaptive Immune System
    Transport of antigen loaded MHC II molecules to surface
    Kinesins move along microtubules consuming ATP
    Factors involved in megakaryocyte development and platelet production



    KLC3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KLC3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/30 Interacting proteins for KLC3 (Q6P5972, 3 ENSP000003758104) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAZP631042, 3, ENSP000003095034MINT-3318724 I2D: score=1 STRING: ENSP00000309503
    KIF5CO602823, ENSP000003933794I2D: score=2 STRING: ENSP00000393379
    YWHAGP619813, ENSP000003063304I2D: score=2 STRING: ENSP00000306330
    YWHAHQ049173, ENSP000002489754I2D: score=3 STRING: ENSP00000248975
    CROCCQ5TZA23, ENSP000003646914I2D: score=1 STRING: ENSP00000364691
    About this table

    Drugs & Compounds
    for KLC3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    KLC3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KLC3
    4 PharmGKB related drug/compound annotations for KLC3 gene    About this table
    Drug/compound PharmGKB Annotation
    Platinum compoundsCA  
    cisplatinCA  
    oxaliplatinCA  
    platinumCA  
    Search CenterWatch for drugs/clinical trials and news about KLC3 

    Transcripts
    for KLC3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for KLC3 gene (2 alternative transcripts): 
    NM_177417.2  NM_145275.1  

    Unigene Cluster for KLC3:

    Kinesin light chain 3
    Hs.298079  [show with all ESTs]
    Unigene Representative Sequence: BC073841
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000589373 ENST00000494686(uc002pbe.3) ENST00000391946(uc002pbf.1 uc010ejy.1)
    ENST00000585434 ENST00000589837 ENST00000590063 ENST00000470402(uc002pbg.1)


    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: KLC3
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    Clone
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    Primer
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    Additional cDNA sequence: 

    BC062998.1 BC073841.1 BC126418.1 BC133037.1 

    4 DOTS entries:

    DT.100818859  DT.95105252  DT.409967  DT.91697570 

    24/25 AceView cDNA sequences (see all 25):

    AW196915 NM_145275 AX747564 BX100808 BC062998 NM_177417 BC073841 AK092481 
    AA926928 AI494116 BI829517 BC025318 BC020346 BI764568 BQ944927 AI279514 
    BF569806 BX361118 BQ310310 BF221863 AA932390 AI338897 BF946077 AA613202 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for KLC3    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
    SP1:                    -                       -                                                               
    SP2:                    -                       -                                                               
    SP3:                                            -                                                               
    SP4:                    -                                                                                       
    SP5:                                -                                                                           


    ECgene alternative splicing isoforms for KLC3

    Expression
    for KLC3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KLC3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCACTCAACA
    KLC3 Expression
    About this image

    KLC3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Definitive endoderm-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See KLC3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KLC3

    SOURCE GeneReport for Unigene cluster: Hs.298079
        SABiosciences Custom PCR Arrays for KLC3
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    In Situ
    Assay Products:     
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    Orthologs
    for KLC3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for KLC3 gene from 7/21 species (see all 21)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Klc31 , 5 kinesin light chain 31, 5 85.69(n)1
    91.05(a)1    		   7 (9.62 cM)5
    2329431  NM_146182.31  NP_666294.11 
     193944375 
    lizard
    (Anolis carolinensis)    		 Reptilia KLC36
    		 --
    		 73(a)
    		 possible ortholog
    		 AAWZ02038453(1352-6180)
    zebrafish
    (Danio rerio)    		 Actinopterygii klc36
    		 kinesin light chain 3
    		 59(a)
    		 1 ↔ 1
    		 15(23010599-23030994)
    fruit fly
    (Drosophila melanogaster)    		 Insecta Klc6
    		 Kinesin light chain
    		 48(a)
    		 1 → many
    		 3L(12739716-12743156)
    worm
    (Caenorhabditis elegans)    		 Secernentea klc-26
    klc-16
    		 Kinesin Light Chain family member (klc-1)
    		 44(a)
    34(a)
    		 many → 1
    possible ortholog
    		 V(5575394-5581697)
    IV(11084084-11086032)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT5G375906
    AT5G530806
    (see all 6)    		 kinesin light chain-related protein
    (see all 6)    		 9(a)
    9(a)
    (see all 6)    		 possible ortholog
    possible ortholog
    (see all 6)    		 5(14927313-14932787)
    5(21520513-21523266)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 4)    		 tetratricopeptide repeat domain containing protein...
    tetratricopeptide repeat containing protein, putat...
    (see all 4)    		 9(a)
    7(a)
    (see all 4)    		 possible ortholog
    possible ortholog
    (see all 4)    		 2(534930-538203)
    2(35212441-35215229)


    ENSEMBL Gene Tree for KLC3 (if available)
    TreeFam Gene Tree for KLC3 (if available) 

    Paralogs
    for KLC3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KLC3 gene
    KLC22  KLC42  ENSG000002565002  KLC12  NPHP32  
    6 SIMAP similar genes for KLC3 using alignment to 4 protein entries:     KLC3_HUMAN (see all proteins):
    KNS2    KLC1    KLC2    KLC4    NPHP3    TTC19

    KLC3 for paralogs           About GeneDecksing



    Genomic Variants
    for KLC3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/296 NCBI SNPs in KLC3 are shown (see all 296)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1867074831,2
    		--45842197(+) CTCTTC/GTTGCC 1 -- us2k10--------
    rs1477446231,2
    		C--45842796(+) AGTTCA/GAGATC 1 -- us2k10--------
    rs1920687891,2
    		--45842803(+) GATCAG/TCCTGG 1 -- us2k10--------
    rs1817294421,2
    		--45842835(+) TCTACG/TAAAAA 1 -- us2k10--------
    rs1872184721,2
    		--45842912(+) AGAATC/GACTTG 1 -- us2k10--------
    rs1451417301,2
    		C--45843066(+) TAGAC-/TATT  
                TATAT     		1 -- us2k10--------
    rs129729851,2
    		C--45843315(+) AGGCGT/GGAGGA 1 -- us2k13Minor allele frequency- G:0.17NA 6
    rs104040251,2
    		C,F--45843405(+) GGGCGC/TGGTGG 1 -- us2k110Minor allele frequency- T:0.50NA WA CSA EA 372
    rs1910943571,2
    		--45843410(+) TGGTGG/TCAGAC 1 -- us2k10--------
    rs1469084631,2
    		--45843484(+) GTTGCA/GGTGAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for KLC3 (45836692 - 45854778 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for KLC3
         2 CNVs: 9802 37708

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for KLC3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    KLC3 for disorders           About GeneDecksing

    OMIM gene information: 601334    OMIM disorders: --

    2 diseases for KLC3:    About MalaCards
    vaccinia    neuronitis

    Human Genome Epidemiology (HuGE) Navigator: KLC3 (3 documents)

    Export disorders for KLC3 gene to outside databases

    Publications
    for KLC3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KLC3 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with KLC3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Sequence analysis of the ERCC2 gene regions in human, mouse, and hamster reveals three linked genes. (PubMed id 8786141)1, 2 Lamerdin J.E.... Carrano A.V. (1996)
    4. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    5. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    6. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
    7. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    8. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    9. LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein. (PubMed id 18784752)1 Yamada M....Hirotsune S. (2008)
    10. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)

    External Searches for KLC3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
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    Genome Databases showing KLC3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 147700 HGNC: 20717 AceView: KLC2L Ensembl:ENSG00000104892 euGenes: HUgn147700
    ECgene: KLC3 H-InvDB: KLC3

    Other Databases showing KLC3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing KLC3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KLC3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for KLC3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for KLC3 gene:
    Search GeneIP for patents involving KLC3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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