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KLC3 Gene

protein-coding   GIFtS: 57
GCID: GC19P045851

Kinesin Light Chain 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Kinesin Light Chain 31 2     KLCt2
KLC2L2 3 5     KNS2B2
KLC22 3     KLC2-like3
Kinesin Light Chain 22 3     

External Ids:    HGNC: 207171   Entrez Gene: 1477002   Ensembl: ENSG000001048927   OMIM: 6013345   UniProtKB: Q6P5973   

Export aliases for KLC3 gene to outside databases

Previous GC identifers: GC19P050538 GC19P045847 GC19P042276


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for KLC3 Gene:
This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the
transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light
chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin
activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it
associates with structural components of sperm tails and mitochondria. (provided by RefSeq, Jul 2008)

GeneCards Summary for KLC3 Gene:
KLC3 (kinesin light chain 3) is a protein-coding gene. Diseases associated with KLC3 include vaccinia, and neuronitis. GO annotations related to this gene include microtubule binding and kinesin binding. An important paralog of this gene is KLC2.

UniProtKB/Swiss-Prot: KLC3_HUMAN, Q6P597
Function: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport

Gene Wiki entry for KLC3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KLC3 gene promoter:
         FAC1   NRSF form 1   MyoD   NRSF form 2   Tal-1beta   ITF-2   Roaz   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKLC3 promoter sequence
   Search Chromatin IP Primers for KLC3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KLC3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13   Ensembl cytogenetic band:  19q13.32   HGNC cytogenetic band: 19q13

KLC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KLC3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P045851:  view genomic region     (about GC identifiers)

Start:
45,836,692 bp from pter      End:
45,854,778 bp from pter
Size:
18,087 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: KLC3_HUMAN, Q6P597 (See protein sequence)
Recommended Name: Kinesin light chain 3  
Size: 504 amino acids; 55364 Da
Subunit: Oligomer composed of two heavy chains and two light chains. Associates with microtubulin in an
ATP-dependent manner. Interacts with KIF5C and ODF1 (By similarity)
Secondary accessions: A0AVM3 A2RUT6 Q6GMU2 Q8NAL1 Q8WWJ9
Alternative splicing: 3 isoforms:  Q6P597-1   Q6P597-2   Q6P597-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KLC3: NX_Q6P597

Explore proteomics data for KLC3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KLC3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_803136.2  
    ENSEMBL proteins: 
     ENSP00000465950   ENSP00000375810   ENSP00000466067   ENSP00000466974   ENSP00000466168  
     ENSP00000436019  
    Reactome Protein details: Q6P597

    KLC3 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for KLC3

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TTC: Tetratricopeptide (TTC) repeat domain containing

    Selected InterPro protein domains (see all 6):
     IPR001440 TPR_1
     IPR011990 TPR-like_helical
     IPR002151 Kinesin_light
     IPR015390 Rabaptin_Rab5-bd_dom
     IPR013026 TPR-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q6P597

    ProtoNet protein and cluster: Q6P597

    UniProtKB/Swiss-Prot: KLC3_HUMAN, Q6P597
    Domain: The heptad repeat (HR) motif is sufficient for interaction with kinesin heavy (KHL) chains and ODF1. The
    TPR region is involved in mitochondrial binding (By similarity)
    Similarity: Belongs to the kinesin light chain family
    Similarity: Contains 5 TPR repeats


    KLC3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KLC3_HUMAN, Q6P597
    Function: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003777microtubule motor activity IEA--
    GO:0005515protein binding ----
    GO:0008017microtubule binding IEA--
    GO:0019894kinesin binding IEA--
         
    KLC3 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for KLC3:
     Decreased POU5F1-GFP protein e  Increased cell number in G2M,  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KLC3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KLC3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KLC3

    miRNA
    Products:
        
    miRTarBase miRNAs that target KLC3:
    hsa-mir-92a-3p (MIRT049334), hsa-mir-30c-5p (MIRT047944), hsa-mir-331-3p (MIRT043375), hsa-mir-484 (MIRT042175)

    Block miRNA regulation of human, mouse, rat KLC3 using miScript Target Protectors
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    SwitchGear 3'UTR luciferase reporter plasmidKLC3 3' UTR sequence
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    GenScript: all cDNA clones in your preferred vector: KLC3 (NM_177417)
    Sino Biological Human cDNA Clone for KLC3
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLC3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KLC3_HUMAN, Q6P597: Cytoplasm, cytoskeleton (Probable). Note=Elongating spermatid tail midpiece, localized in
    outer dense fibers (ODFs) and associates with mitochondria (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton4
    cytosol3
    nucleus2

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005871kinesin complex IEA--
    GO:0005874microtubule IEA--
    GO:0031514motile cilium IEA--
    GO:0035253ciliary rootlet IEA--

    KLC3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for KLC3 About   (see all 6)  
    See pathways by source

    SuperPathContained pathways About
    1Hemostasis
    Hemostasis0.43
    2Class I MHC mediated antigen processing and presentation
    Adaptive Immune System0.41
    3Salmonella infection (KEGG)
    Salmonella infection0.30
    4MHC class II antigen presentation
    MHC class II antigen presentation
    5Kinesins
    Kinesins

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2 Reactome Pathways for KLC3
        MHC class II antigen presentation
    Kinesins


    1 Kegg Pathway  (Kegg details for KLC3):
        Salmonella infection


    KLC3 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KLC3
    Interactions:

        Search GeneGlobe Interaction Network for KLC3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for KLC3 (Q6P5972, 3 ENSP000003758104) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAZP631042, 3, ENSP000003095034MINT-3318724 I2D: score=1 STRING: ENSP00000309503
    KIF5CO602823, ENSP000003933794I2D: score=2 STRING: ENSP00000393379
    YWHAGP619813, ENSP000003063304I2D: score=2 STRING: ENSP00000306330
    YWHAHQ049173, ENSP000002489754I2D: score=3 STRING: ENSP00000248975
    CROCCQ5TZA23, ENSP000003646914I2D: score=1 STRING: ENSP00000364691
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008088axon cargo transport IEA--

    KLC3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KLC3

    4 PharmGKB related drug/compound annotations for KLC3 gene    About this table
    Drug/compound PharmGKB Annotation
    Platinum compoundsCA  
    cisplatinCA  
    oxaliplatinCA  
    platinumCA  



    KLC3 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for KLC3 gene (2 alternative transcripts): 
    NM_177417.2  NM_145275.1  

    Unigene Cluster for KLC3:

    Kinesin light chain 3
    Hs.298079  [show with all ESTs]
    Unigene Representative Sequence: BC073841
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000589373 ENST00000494686(uc002pbe.3) ENST00000391946(uc002pbf.1 uc010ejy.1)
    ENST00000585434 ENST00000589837 ENST00000590063 ENST00000470402(uc002pbg.1)

    miRNA
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      QuantiFast Probe-based Assays in human, mouse, rat KLC3

    Additional mRNA sequence: 

    BC062998.1 BC073841.1 BC126418.1 BC133037.1 

    4 DOTS entries:

    DT.100818859  DT.95105252  DT.409967  DT.91697570 

    Selected AceView cDNA sequences (see all 25):

    AA926928 BX100808 AX747564 AW196915 AK092481 NM_177417 BC073841 NM_145275 
    BI829517 BC062998 BC025318 AI494116 BF569806 BC020346 BX361118 BQ944927 
    BI764568 AI279514 BQ310310 BF221863 AA932390 AI338897 BF946077 BX392380 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for KLC3    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
    SP1:                    -                       -                                                               
    SP2:                    -                       -                                                               
    SP3:                                            -                                                               
    SP4:                    -                                                                                       
    SP5:                                -                                                                           


    ECgene alternative splicing isoforms for KLC3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KLC3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCACTCAACA
    KLC3 Expression
    About this image


    KLC3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Hair (Integumentary System)
             Bulge Stem Cells Bulge
     
     Brain (Nervous System)
             Adult Oligodendrocyte Precursor Cells Lateral Ventricle
    KLC3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KLC3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.298079
        Custom PCR Arrays for KLC3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KLC3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for KLC3 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Klc31 , 5 kinesin light chain 31, 5 85.69(n)1
    91.05(a)1
      7 (9.62 cM)5
    2329431  NM_001286038.11  NP_001272967.11 
     193944375 
    lizard
    (Anolis carolinensis)
    Reptilia KLC36
    kinesin light chain 3
    65(a)
    1 ↔ 1
    AAWZ02038453(1299-10769)
    zebrafish
    (Danio rerio)
    Actinopterygii klc36
    kinesin light chain 3
    59(a)
    1 ↔ 1
    15(23010599-23030994) ENSDARG00000055965
    fruit fly
    (Drosophila melanogaster)
    Insecta Klc6
    Kinesin light chain
    50(a)
    1 → many
    3L(12739716-12743156)
    worm
    (Caenorhabditis elegans)
    Secernentea klc-26
    klc-16
    Protein KLC-1, isoform b
    43(a)
    34(a)
    many ↔ many
    many ↔ many
    V(5575410-5581713) WBGene00002215
    IV(11083735-11086053) WBGene00002214


    ENSEMBL Gene Tree for KLC3 (if available)
    TreeFam Gene Tree for KLC3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KLC3 gene
    KLC22  ENSG000002565002  KLC42  NPHP3-ACAD112  KLC12  
    6 SIMAP similar genes for KLC3 using alignment to 4 protein entries:     KLC3_HUMAN (see all proteins):
    KNS2    KLC1    KLC2    KLC4    NPHP3    TTC19

    KLC3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KLC3 (see all 444)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1867074831,2
    C--45842197(+) CTCTTC/GTTGCC 1 -- us2k10--------
    rs1477446231,2
    C--45842796(+) AGTTCA/GAGATC 1 -- us2k10--------
    rs1920687891,2
    --45842803(+) GATCAG/TCCTGG 1 -- us2k10--------
    rs1817294421,2
    --45842835(+) TCTACG/TAAAAA 1 -- us2k10--------
    rs1872184721,2
    --45842912(+) AGAATC/GACTTG 1 -- us2k10--------
    rs1451417301,2
    C--45843066(+) TAGAC-/TATT  
            
    TATAT
    1 -- us2k10--------
    rs129729851,2
    C--45843315(+) aggcgT/Ggagga 1 -- us2k13Minor allele frequency- G:0.17NA 6
    rs104040251,2
    C,F--45843405(+) gggcgC/Tggtgg 1 -- us2k110Minor allele frequency- T:0.50NA WA CSA EA 372
    rs1910943571,2
    --45843410(+) TGGTGG/TCAGAC 1 -- us2k10--------
    rs1469084631,2
    --45843484(+) GTTGCA/GGTGAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for KLC3 (45836692 - 45854778 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for KLC3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv470146CNV Loss18288195
    nsv833844CNV Loss17160897
    nsv833845CNV Loss17160897
    nsv912146CNV Loss21882294
    nsv458711CNV Gain19166990
    dgv29n64CNV Gain17921354
    nsv442466CNV CNV18776908

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 601334    OMIM disorders: --

    3 diseases for KLC3:    
    About MalaCards
    vaccinia    neuronitis    lung cancer


    KLC3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): KLC3
    Human Genome Epidemiology (HuGE) Navigator: KLC3 (3 documents)

    Export disorders for KLC3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KLC3 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with KLC3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Sequence analysis of the ERCC2 gene regions in human, mouse, and hamster reveals three linked genes. (PubMed id 8786141)1, 2 Lamerdin J.E.... Carrano A.V. (Genomics 1996)
    5. Genome-wide association study reveals novel genetic determinants of DNA repair capacity in lung cancer. (PubMed id 23108145)1 Wang L.E....Wei Q. (Cancer Res. 2013)
    6. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    7. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    8. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    10. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 147700 HGNC: 20717 AceView: KLC2L Ensembl:ENSG00000104892 euGenes: HUgn147700
    ECgene: KLC3 Kegg: 147700 H-InvDB: KLC3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KLC3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for KLC3 gene:
    Search GeneIP for patents involving KLC3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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