External Ids for KLC2 Gene
Previous GeneCards Identifiers for KLC2 Gene
Kinesin is a molecular motor that generates ATP-dependent movement of vesicles and organelles along microtubules. Kinesin consists of 2 light chains, such as KLC2, and 2 heavy chains (see KIF5B; MIM 602809) in a 1:1 stoichiometric ratio (Rahman et al., 1998 [PubMed 9624122]).[supplied by OMIM, Mar 2008]
GeneCards Summary for KLC2 Gene
KLC2 (Kinesin Light Chain 2) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Hemostasis. GO annotations related to this gene include microtubule motor activity and kinesin binding. An important paralog of this gene is KLC4.
UniProtKB/Swiss-Prot for KLC2 Gene
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity).