External Ids for KLC2 Gene
Previous GeneCards Identifiers for KLC2 Gene
Kinesin is a molecular motor that generates ATP-dependent movement of vesicles and organelles along microtubules. Kinesin consists of 2 light chains, such as KLC2, and 2 heavy chains (see KIF5B; MIM 602809) in a 1:1 stoichiometric ratio (Rahman et al., 1998 [PubMed 9624122]).[supplied by OMIM, Mar 2008]
GeneCards Summary for KLC2 Gene
KLC2 (Kinesin Light Chain 2) is a Protein Coding gene. Among its related pathways are Immune System and Signaling by GPCR. GO annotations related to this gene include microtubule motor activity and kinesin binding. An important paralog of this gene is KLC4.
UniProtKB/Swiss-Prot for KLC2 Gene
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity).