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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KIRREL3-AS3 Gene

RNA gene   GIFtS: 29
GCID: GC11P126876

KIRREL3 antisense RNA 3

(Previous names: proline rich 10, non-protein coding RNA 288, KIRREL3 antisense...)
(Previous symbols: PRR10, NCRNA00288)
 Explore 2 diseases affiliated with
KIRREL3-AS3 via our new
 Human Malady Compendium 
Biological research products
for KIRREL3-AS3
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Subcategory (RNA class): lncRNA

Quality score for this RNA gene is 3

Aliases
KIRREL3 Antisense RNA 31 2     Non-Protein Coding RNA 2881
NCRNA002881 2 3     Proline Rich 101
PRR101 2 3     KIRREL3 Antisense Gene Protein 13
FLJ402241     KIRREL3 Antisense RNA 13
KIRREL3 Antisense RNA 3 (Non-Protein Coding)1     Proline-Rich Protein 103

External Ids:    HGNC: 268551   Entrez Gene: 2831652   Ensembl: ENSG000002181097   UniProtKB: Q8N7Y13   
ORGUL members:         
NONCODE:n381798    

Export aliases for KIRREL3-AS3 gene to outside databases

Previous GC identifer: GC11U901880


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_033899.8  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for KIRREL3-AS3
         Other transcription factors

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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIRREL3-AS3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q24.2   Ensembl cytogenetic band:  11q24.2   HGNC cytogenetic band: 11q24.2

KIRREL3-AS3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIRREL3-AS3 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P126876:  view genomic region     (about GC identifiers)

Start:
126,872,805 bp from pter      End:
126,875,953 bp from pter
Size:
3,149 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: KIAS3_HUMAN, Q8N7Y1 (See protein sequence)
Recommended Name: Putative uncharacterized protein KIRREL3-AS3  
Size: 241 amino acids; 25772 Da
Caution: Product of a dubious CDS prediction. May be a non-coding RNA
Secondary accessions: Q14CX1

Explore the universe of human proteins at neXtProt for KIRREL3-AS3: NX_Q8N7Y1

KIRREL3-AS3 Protein expression data from MOPED and PaxDb: --

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q8N7Y1


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
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Animal Models:
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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIRREL3-AS3

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
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Browse Tocris compounds for KIRREL3-AS3
Search CenterWatch for drugs/clinical trials and news about KIRREL3-AS3 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
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About This Section

REFSEQ mRNAs for KIRREL3-AS3 gene: 
NM_173579.1  

Unigene Cluster for KIRREL3-AS3:

KIRREL3 antisense RNA 3
Hs.730461  [show with all ESTs]
Unigene Representative Sequence: NR_040078
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000525678(uc001qef.1)

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Additional cDNA sequence: 

BC113593.1 BC113597.1 NR_040078.1 

2 DOTS entries:

DT.100008414  DT.100019245 

2 AceView cDNA sequences:

NM_173579 AK097543 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

Expression evidence for KIRREL3-AS3:none

KIRREL3-AS3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
KIRREL3-AS3 Expression
About this image
Genevestigator expression for KIRREL3-AS3

SOURCE GeneReport for Unigene cluster: Hs.730461
    SABiosciences Custom PCR Arrays for KIRREL3-AS3

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In Situ
Assay Products:
 

 
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
  --

ENSEMBL Gene Tree for KIRREL3-AS3 (if available)
TreeFam Gene Tree for KIRREL3-AS3 (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/58 NCBI SNPs in KIRREL3-AS3 are shown (see all 58    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs25085571,2
C,F,A,H--126872785(-) CAGACG/ACCTGT 1 -- us2k122Minor allele frequency- A:0.41NS EA NA WA CSA 2340
rs1909750091,2
--126872787(+) AGGTGC/TCTGCA 1 -- us2k10--------
rs1482639181,2
--126872841(+) GAGATC/GCAGGT 1 -- nc-transcript-variant0--------
rs1490063311,2
C--126872872(+) TCCCA-/TTTGGC 1 -- nc-transcript-variant0--------
rs71154731,2
C,F,A,H--126873226(+) CCCGCG/TGCCTC 1 -- nc-transcript-variant12Minor allele frequency- T:0.15NS NA WA 1570
rs1137693221,2
C--126873442(+) GGGCG-/GCGCGCG 1 -- nc-transcript-variant1Minor allele frequency- GC:0.00CSA 2
rs798441521,2
F--126873516(+) CAACTT/AGGAAA 1 -- nc-transcript-variant1Minor allele frequency- A:0.02NA 120
rs1835541281,2
--126873522(+) GGAAAA/TCCGCC 1 -- nc-transcript-variant0--------
rs4944421,2
C,F,A,H--126873592(+) GCCGGT/CGGGAT 1 -- nc-transcript-variant21Minor allele frequency- C:0.41NS EA NA WA CSA 2327
rs1879045361,2
--126873686(+) CAAGCC/TTCCGG 1 -- nc-transcript-variant0--------

HapMap Linkage Disequilibrium report for KIRREL3-AS3 (126872805 - 126875953 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for KIRREL3-AS3: --

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

KIRREL3-AS3 for disorders           About GeneDecksing

2 diseases for KIRREL3-AS3:    About MalaCards
hepatitis b    hepatitis


Export disorders for KIRREL3-AS3 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for KIRREL3-AS3 gene integrated from 9 sources:
(articles sorted by number of sources associating them with KIRREL3-AS3)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  3. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 283165 HGNC: 26855 AceView: FLJ40224 Ensembl:ENSG00000218109 euGenes: HUgn283165
ECgene: KIRREL3-AS3 H-InvDB: KIRREL3-AS3

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for KIRREL3-AS3 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for KIRREL3-AS3 gene:
Search GeneIP for patents involving KIRREL3-AS3

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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