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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KIR3DL3 Gene

protein-coding   GIFtS: 51
GCID: GC19P055270

Killer Cell Immunoglobulin-Like Receptor, Three Domains,...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Killer Cell Immunoglobulin-Like Receptor, Three Domains, Long
Cytoplasmic Tail, 31 2
     CD158 Antigen-Like Family Member Z2 3
Killer Cell Inhibitory Receptor 12 3     KIR442
CD158Z2 3     Killer Cell Ig-Like Receptor KIR3DL72
KIR3DL72 3     Killer Cell Immunoglobulin-Like Receptor 3DL32
KIRC12 3     CD158z Antigen3

External Ids:    HGNC: 163121   Entrez Gene: 1156532   Ensembl: ENSG000002420197   OMIM: 6100955   UniProtKB: Q8N7433   

Export aliases for KIR3DL3 gene to outside databases

Previous GC identifers: GC19P059927 GC00P9Q0007 GC19P055238 GC19P055241 GC19P051558 GC19P055244 GC19P055249 GC19P055254 GC19P055259 GC19P055263


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KIR3DL3 Gene:
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells
and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on
chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster
varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1,
KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or
3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic
domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM),
while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO
protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are
subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the
immune response. This gene is one of the 'framework' loci that is present on all haplotypes. (provided by RefSeq,
Jul 2008)

GeneCards Summary for KIR3DL3 Gene: 
KIR3DL3 (killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3) is a protein-coding gene. Diseases associated with KIR3DL3 include leptospirosis, and vogt-koyanagi-harada disease, and among its related super-pathways are Graft-versus-host disease. An important paralog of this gene is LILRB4.

UniProtKB/Swiss-Prot: KI3L3_HUMAN, Q8N743
Function: Receptor on natural killer cells. May inhibit the activity of NK cells thus preventing cell lysis

Gene Wiki entry for KIR3DL3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KIR3DL3 gene promoter:
         RP58   AML1a   GCNF   Pax-2   Pax-2a   PPAR-gamma1   GCNF-1   PPAR-gamma2   GCNF-2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for KIR3DL3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIR3DL3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.42   Ensembl cytogenetic band:  19q13.42   HGNC cytogenetic band: 19q13.4

KIR3DL3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIR3DL3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P055270:  view genomic region     (about GC identifiers)

Start:
55,235,984 bp from pter      End:
55,248,003 bp from pter
Size:
12,020 bases      Orientation:
plus strand

6 alternative locations:
Chr19+,NW_003571061 450,544-462,562      Chr19+,NW_003571060 628,873-640,888      Chr19+,NW_003571059 707,356-719,373     
Chr19+,NW_003571054 630,167-642,181      Chr19+,NW_003571057 813,263-825,280      Chr19+,NW_003571056 721,241-735,440     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KI3L3_HUMAN, Q8N743 (See protein sequence)
Recommended Name: Killer cell immunoglobulin-like receptor 3DL3 precursor  
Size: 410 amino acids; 44928 Da
Subcellular location: Cell membrane; Single-pass type I membrane protein
Secondary accessions: A9PL62 A9PL64 A9PL65 A9PL66 A9PL67 A9PL68 A9PZV4 A9PZV7 A9PZV8 A9Q066
A9Q0R5 A9Q242 A9Q250 A9Q251 O95056 Q1X775 Q1X777 Q1X778 Q1X779 Q1X780 Q1X781 Q1X782 Q1X783
Q7Z7N4 Q8NHI2 Q8NHI3 Q9UEI4

Explore the universe of human proteins at neXtProt for KIR3DL3: NX_Q8N743

Explore proteomics data for KIR3DL3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N743

  • KIR3DL3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KIR3DL3 Protein Expression
    REFSEQ proteins: NP_703144.2  
    ENSEMBL proteins: 
     ENSP00000291860  

    Human Recombinant Protein Products for KIR3DL3: 
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    Cloud-Clone Corp. Proteins for KIR3DL3 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016021integral to membrane IEA--

    KIR3DL3 for ontologies           About GeneDecksing



    KIR3DL3 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CD: CD molecules
    KIR: Killer cell immunoglobulin-like receptors
    IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing

    3 InterPro protein domains:
     IPR003599 Ig_sub
     IPR013783 Ig-like_fold
     IPR013151 Immunoglobulin

    Graphical View of Domain Structure for InterPro Entry Q8N743

    ProtoNet protein and cluster: Q8N743

    UniProtKB/Swiss-Prot: KI3L3_HUMAN, Q8N743
    Similarity: Belongs to the immunoglobulin superfamily
    Similarity: Contains 3 Ig-like C2-type (immunoglobulin-like) domains


    KIR3DL3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KI3L3_HUMAN, Q8N743
    Function: Receptor on natural killer cells. May inhibit the activity of NK cells thus preventing cell lysis

    Animal Models:

       inGenious Targeting Laboratory - Custom generated mouse model solutions for KIR3DL3 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KIR3DL3 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for KIR3DL3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Allograft rejection
    Antigen processing and presentation0.37

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1         Kegg Pathway  (Kegg details for KIR3DL3):
        Antigen processing and presentation


    KIR3DL3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIR3DL3

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for KIR3DL3 (ENSP000002918604) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000223532ENSP000004008424STRING: ENSP00000400842
    ENSG00000229252ENSP000004099104STRING: ENSP00000409910
    ENSG00000237216ENSP000004091324STRING: ENSP00000409132
    HLA-AENSP000003660054STRING: ENSP00000366005
    HLA-CENSP000003654024STRING: ENSP00000365402
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KIR3DL3 (KI3L3)

    Search CenterWatch for drugs/clinical trials and news about KIR3DL3 / KI3L3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KIR3DL3 gene: 
    NM_153443.3  

    Unigene Cluster for KIR3DL3:

    Killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
    Hs.645224
    Unigene Representative Sequence: AF352324
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000291860(uc002qgu.1)
    miRNA
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    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIR3DL3
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    GenScript: all cDNA clones in your preferred vector: KIR3DL3 (NM_153443)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KIR3DL3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIR3DL3
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIR3DL3
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    Additional mRNA sequence: 

    AF352324.1 AJ938052.1 AJ938053.1 AJ938054.1 AJ938055.1 AJ938056.1 AJ938057.1 AJ938058.1 
    AJ938059.1 AJ938060.1 AJ938061.1 AJ938062.1 AJ938063.1 AJ938064.1 AJ938065.1 AJ938066.1 
    BC136283.1 BC143802.1 

    1 DOTS entry:

    DT.97817222 

    24/93 AceView cDNA sequences (see all 93):

    AF285434 AY366242 AY052498 AF034773 AY223515 AF208054 AY052497 U71199 
    AF002982 AF272389 BV180829 BV204361 BV180934 BV199186 U73394 BV204357 
    BV183858 BV206442 AY250088 X98858 AY366248 BV203729 AF135566 AY223512 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KIR3DL3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTCTCTCTT
    KIR3DL3 Expression
    About this image


    See KIR3DL3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KIR3DL3

    SOURCE GeneReport for Unigene cluster: Hs.645224
        SABiosciences Custom PCR Arrays for KIR3DL3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIR3DL3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for KIR3DL3 gene from 2/7 species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves --
    --
    (see all 62)
    --
    27(a)
    25(a)
    (see all 62)
    many ↔ many
    many ↔ many
    (see all 62)
    AADN03012120.1(25-1435)
    JH376121.1(3529-4219)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    Uncharacterized protein
    (see all 3)
    13(a)
    10(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    GL343329.1(1197670-1218701)
    GL343329.1(823590-844642)
            Species with no ortholog for KIR3DL3

    ENSEMBL Gene Tree for KIR3DL3 (if available)
    TreeFam Gene Tree for KIR3DL3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KIR3DL3 gene
    KIR3DL3  LILRB42  KIR2DL42  LILRB12  KIR2DS42  LILRA62  LILRA52  IGSF12  
    KIR3DL12  OSCAR2  NCR12  LILRA42  ENSG000002177922  TARM12  KIR3DX12  LILRA32  
    LILRB52  LILRA12  KIR3DS12  KIR2DL12  LILRB22  A1BG2  KIR3DL22  LILRA22  
    KIR2DL32  FCAR2  GP62  LILRB32  
    18/54 SIMAP similar genes for KIR3DL3 using alignment to 7 protein entries:     KI3L3_HUMAN (see all proteins) (see all similar genes):
    KIR411    KIR2DS    p58    KIR3DP1    KIR-K39    KIR-K15
    KIR412    KIR-K36    KIR221    KIR3DL2    KIR2DL3    KIR-K3
    KIR-K9    KIR-K65    KIR-K78    1060P11.3    KIR222    KIR-K64

    KIR3DL3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: KI3L3_HUMAN, Q8N743
    Polymorphism: Various different KIR3DL3 alleles are known: KIR3DL3*00101, KIR3DL3*00102, KIR3DL3*00103,
    KIR3DL3*00201, KIR3DL3*00202, KIR3DL3*00203, KIR3DL3*00204, KIR3DL3*00205, KIR3DL3*00206, KIR3DL3*00207,
    KIR3DL3*0030101 KIR3DL3*0030102, KIR3DL3*00401, KIR3DL3*00402, KIR3DL3*005, KIR3DL3*00601, KIR3DL3*00602,
    KIR3DL3*007, KIR3DL3*00801, KIR3DL3*00802, KIR3DL3*00901, KIR3DL3*00902, KIR3DL3*010, KIR3DL3*01101,
    KIR3DL3*01102, KIR3DL3*012, KIR3DL3*01301, KIR3DL3*01302, KIR3DL3*01303, KIR3DL3*01304, KIR3DL3*01305,
    KIR3DL3*01306, KIR3DL3*01307, KIR3DL3*01401, KIR3DL3*01402, KIR3DL3*01403, KIR3DL3*01404, KIR3DL3*01405,
    KIR3DL3*015 KIR3DL3*016, KIR3DL3*017, KIR3DL3*018, KIR3DL3*019, KIR3DL3*020, KIR3DL3*021, KIR3DL3*022,
    KIR3DL3*023, KIR3DL3*024, KIR3DL3*025, KIR3DL3*026, KIR3DL3*027, KIR3DL3*028, KIR3DL3*029, KIR3DL3*030 and
    KIR3DL3*031. The sequence shown corresponds to the alleles KIR3DL3*002


    10/355 SNPs in KIR3DL3 are shown (see all 355)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0606134
    ----see VAR_0606132 R S mis40--------
    VAR_0606124
    ----see VAR_0606122 R W mis40--------
    VAR_0606184
    ----see VAR_0606182 H Y mis40--------
    VAR_0606114
    ----see VAR_0606112 N K mis40--------
    VAR_0606204
    ----see VAR_0606202 E D mis40--------
    VAR_0194264
    ----see VAR_0194262 V I mis40--------
    VAR_0560924
    ----see VAR_0560922 A P mis40--------
    VAR_0606144
    ----see VAR_0606142 R H mis40--------
    VAR_0606164
    ----see VAR_0606162 N T mis40--------
    VAR_0606194
    ----see VAR_0606192 V D mis40--------

    HapMap Linkage Disequilibrium report for KIR3DL3 (55235984 - 55248003 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/25 variations for KIR3DL3 (see all 25):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2667609CNV Deletion23128226
    dgv575e201CNV Deletion23290073
    dgv577e201CNV Deletion23290073
    esv2668465CNV Deletion23128226
    esv2718910CNV Deletion23290073
    dgv667e199CNV Deletion23128226
    dgv17e196CNV Deletion17116639
    dgv576e201CNV Deletion23290073
    esv2718872CNV Deletion23290073
    dgv16e196CNV Duplication17116639


    Locus Specific Mutation Databases (LSDB): KIR3DL3
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610095    OMIM disorders: --

    20/23 diseases for KIR3DL3 (see all 23):    About MalaCards
    leptospirosis    vogt-koyanagi-harada disease    hematopoietic stem cell transplantation    hepatitis b virus infection
    tropical spastic paraparesis    spastic paraparesis    familial mediterranean fever    ankylosing spondylitis
    cervical intraepithelial neoplasia    leprosy    spondylitis    behcet's disease
    hepatitis b    spasticity    gastritis    hepatitis c
    type 1 diabetes    psoriasis    hepatitis    multiple sclerosis


    KIR3DL3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): KIR3DL3
    Human Genome Epidemiology (HuGE) Navigator: KIR3DL3 (65 documents)

    Export disorders for KIR3DL3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KIR3DL3 gene, integrated from 9 sources (see all 73):
    (articles sorted by number of sources associating them with KIR3DL3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Inhibition of natural killer cell activation signals by killer cell immunoglobulin-like receptors (CD158). (PubMed id 11513144)1, 2, 3 Long E.O....Watzl C. (2001)
    2. Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya. (PubMed id 19000141)1, 4, 9 Velickovic M....Dunckley H. (2009)
    3. Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore. (PubMed id 18668235)1, 4, 9 Lee Y.C....Ren E.C. (2008)
    4. Polymorphisms of killer cell immunoglobulin-like receptor gene: possible association with susceptibility to or clearance of hepatitis B virus infection in Chinese Han population. (PubMed id 18074414)1, 4, 9 Zhi-ming L....Yue-ran Z. (2007)
    5. The beneficial impact of missing KIR ligands and abse nce of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population. (PubMed id 20173784)1, 4 Wu G.Q....Huang H. (2010)
    6. HLA-DQA1*0505 sharing and Killer Immunoglobulin-like receptors in sub fertile couples: report of the 15th International Histocompati bility Workshop. (PubMed id 20210919)1, 4 Varla-Leftherioti M....Spyropoulou-Vlachou M. (2010)
    7. Immunogenetic characteristics of patients with autoim mune gastritis. (PubMed id 20082482)1, 4 Oksanen A.M....Partanen J.A. (2010)
    8. Inhibitory KIR and specific HLA-C gene combinations c onfer susceptibility to or protection against chronic hepatitis B. (PubMed id 20643584)1, 4 Gao X....Zhao Y. (2010)
    9. Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection. (PubMed id 20878400)1, 4 Wauquier N....Vieillard V. (2010)
    10. Influence of HLA class I and HLA-KIR compound genotyp es on HIV-2 infection and markers of disease progression in a Manjako community in West Africa. (PubMed id 20519398)1, 4 Yindom L.M....Carrington M. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 115653 HGNC: 16312 AceView: KIR2DL4 Ensembl:ENSG00000242019 euGenes: HUgn115653
    ECgene: KIR3DL3 Kegg: 115653 H-InvDB: KIR3DL3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KIR3DL3 Pharmacogenomics, SNPs, Pathways
    IPD-KIR Databasehttp://www.ebi.ac.uk/cgi-bin/ipd/kir/view_nomenclature.cgi?kir.3dl3

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KIR3DL3 gene:
    Search GeneIP for patents involving KIR3DL3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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