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KIR3DL2 Gene

protein-coding   GIFtS: 57
GCID: GC19P055361

Killer Cell Immunoglobulin-Like Receptor, Three Domains,...

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Killer Cell Immunoglobulin-Like Receptor, Three Domains, Long
Cytoplasmic Tail, 21 2
     NKAT4B2
NKAT42 3 5     Killer Cell Immunoglobulin-Like Receptor 3DL22
Natural Killer-Associated Transcript 42 3     Killer Cell Immunoglobulin-Like Receptor KIR3DL22
CD158K2 3     Killer Ig Receptor2
NKAT-42 3     KIR Antigen 3DL22
CD158 Antigen-Like Family Member K2 3     Natural Killer Cell Inhibitory Receptor2
MHC Class I NK Cell Receptor2 3     p1402
P70 Natural Killer Cell Receptor Clone CL-52 3     P70 Killer Cell Inhibitory Receptor2
P70 NK Receptor CL-52 3     CD158k Antigen3

External Ids:    HGNC: 63391   Entrez Gene: 38122   Ensembl: ENSG000002404037   OMIM: 6049475   UniProtKB: P436303   

Export aliases for KIR3DL2 gene to outside databases

Previous GC identifers: GC19U990058 GC19P055664 GC19P060005 GC19P060010 GC19P060053 GC19P059939 GC19P051684


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for KIR3DL2 Gene:
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells
and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on
chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster
varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1,
KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or
3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic
domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM),
while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO
protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are
subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the
immune response. This gene is one of the 'framework' loci that is present on all haplotypes. Alternatively
spliced transcript variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Jun
2011)

GeneCards Summary for KIR3DL2 Gene:
KIR3DL2 (killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2) is a protein-coding gene. An important paralog of this gene is LILRB4.

UniProtKB/Swiss-Prot: KI3L2_HUMAN, P43630
Function: Receptor on natural killer (NK) cells for HLA-A alleles. Inhibits the activity of NK cells thus
preventing cell lysis

Gene Wiki entry for KIR3DL2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the KIR3DL2 gene promoter:
         CREB   GATA-3   p53   deltaCREB   CUTL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKIR3DL2 promoter sequence
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Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KIR3DL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.4   Ensembl cytogenetic band:  19q13.42   HGNC cytogenetic band: 19q13.4

KIR3DL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIR3DL2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P055361:  view genomic region     (about GC identifiers)

Start:
55,361,898 bp from pter      End:
55,378,662 bp from pter
Size:
16,765 bases      Orientation:
plus strand

5 alternative locations:
Chr19+,NW_003571055 495,694-512,488      Chr19+,NW_003571056 830,353-839,014      Chr19+,NW_003571058 832,360-849,154     
Chr19+,NW_003571060 754,833-771,582      Chr19+,NW_003571059 769,010-785,804     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: KI3L2_HUMAN, P43630 (See protein sequence)
Recommended Name: Killer cell immunoglobulin-like receptor 3DL2 precursor  
Size: 455 amino acids; 50230 Da
Secondary accessions: Q13238 Q14947 Q14948 Q92684 Q95366 Q95367 Q95368
Alternative splicing: 2 isoforms:  P43630-1   P43630-2   

Explore the universe of human proteins at neXtProt for KIR3DL2: NX_P43630

Explore proteomics data for KIR3DL2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn179, Asn239, Asn273, Asn306
  • Modification sites at PhosphoSitePlus

  • See KIR3DL2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001229796.1  NP_006728.2  

    ENSEMBL proteins: 
     ENSP00000325525   ENSP00000270442  
    Reactome Protein details: P43630

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CD: CD molecules
    KIR: Killer cell immunoglobulin-like receptors
    IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing

    2 InterPro protein domains:
     IPR003599 Ig_sub
     IPR013783 Ig-like_fold

    Graphical View of Domain Structure for InterPro Entry P43630

    ProtoNet protein and cluster: P43630

    1 Blocks protein domain: IPB003599 Immunoglobulin subtype

    UniProtKB/Swiss-Prot: KI3L2_HUMAN, P43630
    Similarity: Belongs to the immunoglobulin superfamily
    Similarity: Contains 3 Ig-like C2-type (immunoglobulin-like) domains


    Find genes that share domains with KIR3DL2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KI3L2_HUMAN, P43630
    Function: Receptor on natural killer (NK) cells for HLA-A alleles. Inhibits the activity of NK cells thus
    preventing cell lysis

         Genatlas biochemistry entry for KIR3DL2:
    natural killer cell immunoglobulin-like inhibitory receptor for HLA-B antigens,3DL2,70kDa,with several
    alternatively spliced (truncated) forms

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for KIR3DL2

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    hsa-mir-132-3p (MIRT021805)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KI3L2_HUMAN, P43630: Cell membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular2
    endoplasmic reticulum1
    endosome1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral component of plasma membrane TAS7716543

    Find genes that share ontologies with KIR3DL2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for KIR3DL2 About    
    See pathways by source

    SuperPathContained pathways About
    1Allograft rejection
    Graft-versus-host disease0.65
    Antigen processing and presentation0.36
    2Class I MHC mediated antigen processing and presentation
    Adaptive Immune System0.41
    3Immune response Role of DAP12 receptors in NK cells
    Natural killer cell mediated cytotoxicity0.31
    4Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
    Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


    Find genes that share SuperPaths with KIR3DL2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for KIR3DL2
        Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell


    3 Kegg Pathways  (Kegg details for KIR3DL2):
        Antigen processing and presentation
    Natural killer cell mediated cytotoxicity
    Graft-versus-host disease

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KIR3DL2
    Interactions:

        GeneGlobe Interaction Network for KIR3DL2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for KIR3DL2 (P436303 ENSP000003255254) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HLA-AP304433, ENSP000003660054I2D: score=1 I2D: score=1 STRING: ENSP00000366005
    ENSG00000224320P304433I2D: score=1 
    ENSG00000229215P304433I2D: score=1 
    ENSG00000223532ENSP000004008424STRING: ENSP00000400842
    ENSG00000229252ENSP000004099104STRING: ENSP00000409910
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006968cellular defense response TAS7716543
    GO:0050776regulation of immune response TAS--

    Find genes that share ontologies with KIR3DL2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for KIR3DL2 (KI3L2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KIR3DL2 gene (2 alternative transcripts): 
    NM_001242867.1  NM_006737.3  

    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000326321(uc002qho.4 uc010esh.3) ENST00000270442
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      QuantiTect SYBR Green Assays in human, mouse, rat KIR3DL2
      QuantiFast Probe-based Assays in human, mouse, rat KIR3DL2

    5 AceView cDNA sequences:

    BI909683 NM_153443 L41268 NM_014511 NM_014218 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KIR3DL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    KIR3DL2 Expression
    About this image


    KIR3DL2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Natural Killer Cells Peripheral Blood
    KIR3DL2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KIR3DL2 Protein Expression
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for KIR3DL2 gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kir3dl25 killer cell immunoglobulin-like receptor, three domains, more   --   X (58.45 cM) 136448107 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    16(a)
    1 → many
    GL343329.1(1197670-1218701)


    ENSEMBL Gene Tree for KIR3DL2 (if available)
    TreeFam Gene Tree for KIR3DL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KIR3DL2 gene
    LILRB42  KIR2DL42  LILRB12  KIR2DS42  LILRA62  LILRA52  IGSF12  KIR3DL12  
    OSCAR2  NCR12  LILRA42  ENSG000002177922  TARM12  KIR3DX12  LILRA32  LILRB52  
    KIR3DL32  LILRA12  KIR3DS12  KIR2DL12  A1BG2  LILRB22  LILRA22  KIR2DL32  
    FCAR2  GP62  LILRB32  
    Selected SIMAP similar genes for KIR3DL2 using alignment to 45 protein entries:     KI3L2_HUMAN (see all proteins) (see all similar genes):
    p140    kir3d    KIR411    KIR-K39    KIR3DL1/2V    KIR3DL1
    KIR3DSL1    KIR-K15    KIR-123FM    KIR3DS1    KIR2DL3    KIR221
    KIR-K78    KIR-K36    KIR2DS2S3    KIR-K61    KIR-K65    KIR2DL2

    Find genes that share paralogs with KIR3DL2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KIR3DL2 (see all 621)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1405839281,2
    C,Funtested155365482(+) GACCCC/TCTGGA 16 P syn11Minor allele frequency- T:0.02EU 923
    rs1835378121,2
    C--55360416(+) TGAACA/CAACAA 2 -- us2k10--------
    rs1861698291,2
    --55360453(+) ATCCCC/TGAAGT 2 -- us2k10--------
    rs20047171,2
    C,F,A,H--55360538(-) TCATCT/CCTTGA 6 -- us2k110Minor allele frequency- C:0.19NS EA NA CSA 586
    rs1481726571,2
    C--55360585(+) CAATTA/GCTATG 6 -- us2k10--------
    rs1452566871,2
    C--55360594(+) TGCTA-/TTTT  
            
    TTTTT
    2 -- us2k10--------
    rs3715457671,2
    C--55360651(+) GTGGCA/GGATCT 8 -- us2k10--------
    rs3732755951,2
    C--55360652(+) TGGCAG/TATCTC 8 -- us2k10--------
    rs3760543411,2
    C--55360660(+) TCTCAA/GTCACT 8 -- us2k10--------
    rs351893011,2
    C,F--55360675(+) ACCTCT/CGCCTC 8 -- us2k13Minor allele frequency- C:0.40NA CSA 5

    HapMap Linkage Disequilibrium report for KIR3DL2 (55361898 - 55378662 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for KIR3DL2 (see all 27):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2667609CNV Deletion23128226
    dgv577e201CNV Deletion23290073
    esv2718932CNV Deletion23290073
    esv2661467CNV Deletion23128226
    dgv667e199CNV Deletion23128226
    esv2718931CNV Deletion23290073
    esv2718872CNV Deletion23290073
    nsv458810CNV Loss19166990
    nsv471706CNV Loss15918152
    esv32688CNV Loss17666407

    Human Gene Mutation Database (HGMD): KIR3DL2
    Locus Specific Mutation Databases (LSDB): KIR3DL2

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604947    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for KIR3DL2:
    Cutaneous T cell lymphoma

    Find genes that share disorders with KIR3DL2           About GenesLikeMe

    1 Novoseek inferred disease relationship for KIR3DL2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lymphoma 10.6 2 11337356 (2)

    Genetic Association Database (GAD): KIR3DL2
    Human Genome Epidemiology (HuGE) Navigator: KIR3DL2 (75 documents)

    Export disorders for KIR3DL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KIR3DL2 gene, integrated from 10 sources (see all 111):
    (articles sorted by number of sources associating them with KIR3DL2)
        Utopia: connect your pdf to the dynamic
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    1. Alternatively spliced forms of human killer inhibitory receptors. (PubMed id 8662091)1, 2, 3 Doehring C.... Colonna M. (Immunogenetics 1996)
    2. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. (PubMed id 7716543)1, 2, 3 Colonna M. and Samaridis J. (Science 1995)
    3. [The study of killer cell immunoglobulin-like receptor 3DL2 gene polymorphisms and pre-eclampsia]. (PubMed id 19953898)1, 4, 9 Wang X.L....Sun C.J. (Zhonghua Yi Xue Za Zhi 2009)
    4. [Allelic polymorphism analysis of killer cell immunoglobulin-like receptor gene 3DL2 in Zhejiang Han population]. (PubMed id 16767680)1, 4, 9 Jiang K....Yan L.X. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2006)
    5. The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population. (PubMed id 20173784)1, 4 Wu G.Q....Huang H. (Bone Marrow Transplant. 2010)
    6. HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop. (PubMed id 20210919)1, 4 Varla-Leftherioti M....Spyropoulou-Vlachou M. (Tissue Antigens 2010)
    7. Immunogenetic characteristics of patients with autoimmune gastritis. (PubMed id 20082482)1, 4 Oksanen A.M....Partanen J.A. (World J. Gastroenterol. 2010)
    8. Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B. (PubMed id 20643584)1, 4 Gao X....Zhao Y. (Clin. Immunol. 2010)
    9. Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection. (PubMed id 20878400)1, 4 Wauquier N....Vieillard V. (Immunogenetics 2010)
    10. Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa. (PubMed id 20519398)1, 4 Yindom L.M....Carrington M. (J. Virol. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3812 HGNC: 6339 AceView: KIR2DL1 Ensembl:ENSG00000240403 euGenes: HUgn3812
    ECgene: KIR3DL2 Kegg: 3812 H-InvDB: KIR3DL2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KIR3DL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KIR3DL2 gene:
    Search GeneIP for patents involving KIR3DL2

    GeneCards and IP:
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