KIR2DL4 Gene
protein-coding GIFtS: 59
GCID: GC19P055265
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killer cell immunoglobulin-like receptor, two domains, long...
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Aliases
for KIR2DL4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long CytoplasmicTail, 41 2 | | 103AS1 | | CD158D1 2 3 | | 15.2121 | | KIR103AS2 3 5 | | KIR1032 | | Killer Cell Inhibitory Receptor 103AS2 3 | | Killer Cell Immunoglobulin-Like Receptor 2DL42 | | G9P2 3 | | Killer Ig Receptor2 | | KIR-103AS2 3 | | Natural Killer Cell Inhibitory Receptor2 | | CD158 Antigen-Like Family Member D2 3 | | NK Cell Receptor2 | | MHC Class I NK Cell Receptor KIR103AS2 3 | | CD158d Antigen3 |
Export aliases for KIR2DL4 gene to outside databasesPrevious GC identifers: GC19P055439 GC19P055661 GC19P059973 GC19P060007 GC00P9Q0057 GC19P9H0057 GC19P9I0057 GC19P060018 GC19P060022 GC19P060023 GC19P055239 GC19P055242 GC19P051637 GC19P055247 GC19P055250 GC19P055255 GC19P055260 |
Summaries
for KIR2DL4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KIR2DL4:
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells andsubsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies amonghaplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). TheKIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they havea long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signalsupon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the shortcytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein totransduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIRproteins are thought to play an important role in regulation of the immune response. This gene is one of the'framework' loci that is present on all haplotypes. Alternative splicing results in multiple transcript variants.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: KI2L4_HUMAN, Q99706Function: Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventingcell lysis
Gene Wiki entry for KIR2DL4
|
Genomic Views
for KIR2DL4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIR2DL4 gene promoter:
GCNF AREB6 CREB RORalpha1 PPAR-gamma1 deltaCREB GCNF-1 PPAR-gamma2 GCNF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIR2DL4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIR2DL4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.4 Ensembl cytogenetic band: 19q13.42 HGNC cytogenetic band: 19q13.4KIR2DL4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P055265: view genomic region
(about GC identifiers)
Start:
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55,236,002 bp from pter |
End:
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55,325,972 bp from pter |
Size:
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89,971 bases |
Orientation:
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plus strand |
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Proteins
for KIR2DL4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KI2L4_HUMAN, Q99706 (See
protein sequence)Recommended Name: Killer cell immunoglobulin-like receptor 2DL4 precursor Size: 377 amino acids; 41487 Da
Subunit: Interacts with ARRB2
Subcellular location: Cell membrane; Single-pass type I membrane protein
Secondary accessions: A8W795 O14621 O14622 O14623 O14624 O43534 P78400 P78401 Q8N738 Q99559 Q99560Q99561 Q99562 Q9UQJ7Alternative splicing: 6 isoforms: Q99706-1 Q99706-2 Q99706-3 Q99706-4 Q99706-5 Q99706-6 Explore the universe of human proteins at neXtProt for KIR2DL4: NX_Q99706
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q99706
KIR2DL4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001074239.1 NP_001074241.1 NP_002246.5
ENSEMBL proteins: ENSP00000351988 ENSP00000339634 ENSP00000350088 ENSP00000379588 ENSP00000345331 ENSP00000379584 ENSP00000379580 Reactome Protein details: Q99706
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
KIR2DL4 for ontologies About GeneDecksing
KIR2DL4 Antibody Products:
Assay Products for KIR2DL4: |
Protein
Domains /
Families
for KIR2DL4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KIR2DL4 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q99706ProtoNet protein and cluster: Q99706 UniProtKB/Swiss-Prot: KI2L4_HUMAN, Q99706Similarity: Belongs to the immunoglobulin superfamilySimilarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains |
Function
for KIR2DL4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KI2L4_HUMAN, Q99706Function: Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventingcell lysis Genatlas biochemistry entry for KIR2DL4:natural killer cell immunoglobulin-like inhibitory receptor for HLA-C antigens,2DL4,with several alternatively spliced(truncated) forms
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIR2DL4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIR2DL4 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for KIR2DL4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIR2DL4 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
KIR2DL4 for ontologies About GeneDecksing
|
Pathways & Interactions
for KIR2DL4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Immune System | | | 2 | Immune response CD16 signaling in NK cells | | | 3 | Natural killer cell mediated cytotoxicity | | | 4 | Cleavage of Alpha-1-Microglobulin | | | 5 | Allograft rejection | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for KIR2DL4
1  GeneGo (Thomson Reuters) Pathway for KIR2DL4
3 
Reactome Pathways for KIR2DL4
2 
Kegg Pathways (Kegg details for KIR2DL4):
KIR2DL4 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KIR2DL4
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
5/16 Interacting proteins for KIR2DL4 (Q997063 ENSP000003396344) via UniProtKB, MINT, STRING, and/or I2D (see all 16)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
KIR2DL4 for ontologies About GeneDecksing
|
Drugs & Compounds
for KIR2DL4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
KIR2DL4 for compounds About GeneDecksing
 Browse Tocris compounds for KIR2DL4
1 Novoseek chemical compound relationship for KIR2DL4 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| arginine |
11.5 |
1 |
11254692 (1) |
Search CenterWatch for drugs/clinical trials and news about KIR2DL4 / KI2L4
|
Transcripts
for KIR2DL4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KIR2DL4 gene (3 alternative transcripts): NM_001080770.1 NM_001080772.1 NM_002255.5 Unigene Clusters for KIR2DL4: Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 Hs.661219 [show with all ESTs], Hs.743945 [show with all ESTs]Unigene Representative Sequences: NM_002255, NM_0012583839 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000359085(uc021vbn.1 uc002qhh.3 uc002qhj.3 uc010esd.3 uc002qhf.3 uc002qhg.3 uc002qhi.3)
ENST00000486965 ENST00000345540 ENST00000357494 ENST00000463062 ENST00000396293
ENST00000346587 ENST00000396289(uc010yfl.2 uc010ese.3) ENST00000396284
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIR2DL4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIR2DL4 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): KIR2DL4 (NM_001080770) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIR2DL4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIR2DL4 |
Additional cDNA sequence: AF002979.1 AF034771.1 AF034773.1 AF285436.1 AK309531.1 AK310066.1 AY052498.1 AY223515.1 AY250088.1 AY359817.1 AY789058.1 AY789059.1 AY789062.1 BC041611.1 DQ266438.1 DQ272466.1 EU194340.1 EU194342.1 U71199.1 U73394.1 X99479.1 Y13054.1 4 DOTS entries: DT.452498 DT.86845912 DT.86845913 DT.100777728 24/93 AceView cDNA sequences (see all 93): AY366242 AF034773 AF285434 AF208054 AY052498 AY052497 AY223515 X97232 BV206442 BV199144 AF285436 AF272389 AY223512 X99480 X97229 AF022044 BV206441 NM_002255 AY223513 AF276292 L41347 BV180934 BM917014 AY250088
GeneLoc Exon Structure
|
Expression
for KIR2DL4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KIR2DL4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See KIR2DL4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KIR2DL4
SOURCE GeneReport for Unigene clusters: Hs.661219 Hs.743945
SABiosciences Custom PCR Arrays for KIR2DL4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIR2DL4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat KIR2DL4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIR2DL4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIR2DL4 |
Orthologs
for KIR2DL4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for KIR2DL4 gene from 2/5 species (see all 5) About this table
ENSEMBL Gene Tree for KIR2DL4 (if available)
TreeFam Gene Tree for KIR2DL4 (if available) |
Paralogs
for KIR2DL4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KIR2DL4 gene
- LILRB42 LILRB12 LILRA62 IGSF12 LILRA52 KIR3DL12 OSCAR2 NCR12
- LILRA42 ENSG000002177922 TARM12 KIR3DX12 LILRA32 LILRB52 KIR3DL32 LILRA12
- KIR2DL12 LILRB22 A1BG2 KIR2DL22 LILRA22 KIR3DL22 KIR2DL32 FCAR2
- LILRB32 GP62
18/51 SIMAP similar genes for KIR2DL4 using alignment to 35 protein entries: KI2L4_HUMAN (see all proteins)
(see all similar genes):KIR-G2 KIR-G1 KIR2DL5A KIR2DLX KIR2DL5B KIR411
p140 KIR221 KIR-K15 KIR-K39 KIR-K36 KIR2DL3
KIR2DL2 KIR-K65 KIR412 KIR2DS2 KIR2DL1 KIR-K61
KIR2DL4 for paralogs About GeneDecksing
|
Genomic Variants
for KIR2DL4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KIR2DL4 (55236002 - 55325972 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 38 variations for KIR2DL4
15/38 CNVs (see all 38): 50215 89325 9816 50217 50223 50222 73425 78276 53768 50218 38822 50220 50219 53576 30084
Human Gene Mutation Database (HGMD): KIR2DL4
Locus Specific Mutation Databases (LSDB): KIR2DL4
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIR2DL4 |
|
Disorders
/ Diseases
for KIR2DL4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KIR2DL4 for disorders About GeneDecksing
OMIM gene information: 604945
OMIM disorders: --
20/29  diseases for KIR2DL4 (see all 29): About MalaCardsvogt-koyanagi-harada disease tropical spastic paraparesis spastic paraparesis pre-eclampsia
familial mediterranean fever cervical intraepithelial neoplasia spontaneous abortion xerophthalmia
ankylosing spondylitis systemic lupus erythematosus lupus erythematosus gastroenteritis
spasticity spondylitis leptospirosis behcet's disease
eclampsia multiple sclerosis hepatitis c leprosy
1 Novoseek disease relationship for KIR2DL4 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
1 |
12616484 (1) |
Genetic Association Database (GAD): KIR2DL4
Human Genome Epidemiology (HuGE) Navigator: KIR2DL4 (76 documents)
Export disorders for KIR2DL4 gene to outside databases
|
Publications
for KIR2DL4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KIR2DL4 gene, integrated from 9 sources (see all 138):
(articles sorted by number of sources associating them with KIR2DL4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- NK cell receptor gene of the KIR family with two IG domains but highest homology to KIR receptors with three IG domains. (PubMed id 8946682)1, 2, 3, 9 Selvakumar A.... Dupont B. (1996)
- The elucidation of KIR2DL4 gene polymorphism. (PubMed id 18082267)1, 2, 9 Schellekens J.... Rozemuller E.H. (2008)
- Genomic organization and allelic polymorphism of the human killer cell inhibitory receptor gene KIR103. (PubMed id 9234477)1, 2, 9 Selvakumar A.... Dupont B. (1997)
- An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cells. (PubMed id 18604210)1, 2 Yu M.-C.... Ge B.-X. (2008)
- A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia. (PubMed id 15730517)1, 4 Arnheim L....Sanjeevi C.B. (2005)
- Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population. (PubMed id 15896204)1, 4 Jiang K....Yan L.X. (2005)
- Maternal KIR repertoire is not associated with recurrent spontaneous abortion. (PubMed id 15333596)1, 4 Witt C.S....Christiansen F.T. (2004)
- Alleles of the KIR2DL4 receptor and their lack of association with pre-eclampsia. (PubMed id 11754000)1, 4 Witt C.S.... Christiansen F.T. (2002)
- Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. (PubMed id 9430220)1, 2 Valiante N.M.... Parham P. (1997)
- Polymorphism and domain variability of human killer cell inhibitory receptors. (PubMed id 9059894)1, 2 Selvakumar A.... Dupont B. (1997)
|
External Searches for KIR2DL4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KIR2DL4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KIR2DL4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KIR2DL4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KIR2DL4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KIR2DL4 gene:
Search GeneIP for patents involving KIR2DL4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIR2DL4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KIR2DL4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KIR2DL4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIR2DL4 | | | OriGene Protein Over-expression Lysate for KIR2DL4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KIR2DL4 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIR2DL4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIR2DL4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KIR2DL4 | | OriGene Custom Protein Services for KIR2DL4 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIR2DL4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIR2DL4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIR2DL4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIR2DL4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIR2DL4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIR2DL4 |
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 | | | KIR2DL4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIR2DL4 |
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