KIR2DL3 Gene
protein-coding GIFtS: 60
GCID: GC19P055267
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killer cell immunoglobulin-like receptor, two domains, long...
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Aliases
for KIR2DL3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long CytoplasmicTail, 31 2 | | Nkat2b1 | | CD158B21 2 3 | | CD158b2 | | NKAT22 3 5 | | GL1832 | | P581 | | KIR-K7b2 | | Killer Inhibitory Receptor Cl 2-32 3 | | KIR-K7c2 | | Natural Killer-Associated Transcript 22 3 | | NK-Receptor1 | | KIR-023GB2 3 | | NKAT2 | | KIRCL232 3 | | NKAT2A2 | | NKAT-22 3 | | NKAT2B2 | | CD158 Antigen-Like Family Member B22 3 | | Killer Cell Immunoglobulin-Like Receptor 2DL32 | | MHC Class I NK Cell Receptor2 3 | | Natural Killer Associated Transcript 22 | | P58 Natural Killer Cell Receptor Clone CL-62 3 | | Natural Killer Cell Inhibitory Receptor KIR2DL32 | | P58 NK Receptor CL-62 3 | | P58.2 MHC Class-I Specific NK Receptor2 | | P58.2 MHC Class-I-Specific NK Receptor2 3 | | NKAT2a3 | | Cl-61 | | NKAT2b3 | | Nkat21 | | CD158b2 Antigen3 | | Nkat2a1 | | |
Export aliases for KIR2DL3 gene to outside databasesPrevious GC identifers: GC19U990051 GC19P059737 GC19P059928 GC19P059930 GC19P059941 GC19P059940 GC19P059942 GC19P059943 GC19P059944 GC19P055240 GC19P055243 GC19P055248 GC19P055252 GC19P055256 GC19P055261 |
Summaries
for KIR2DL3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KIR2DL3:
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells andsubsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies amonghaplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). TheKIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they havea long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signalsupon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the shortcytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein totransduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIRproteins are thought to play an important role in regulation of the immune response. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: KI2L3_HUMAN, P43628Function: Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activityof NK cells thus preventing cell lysis
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Genomic Views
for KIR2DL3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIR2DL3 gene promoter:
PPAR-gamma1 GATA-3 Pax-2 Pax-2a PPAR-gamma2 GATA-1 GATA-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIR2DL3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIR2DL3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.4 Ensembl cytogenetic band: 19q13.42 HGNC cytogenetic band: 19q13.4KIR2DL3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P055267: view genomic region
(about GC identifiers)
Start:
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55,249,974 bp from pter |
End:
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55,295,776 bp from pter |
Size:
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45,803 bases |
Orientation:
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plus strand |
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Proteins
for KIR2DL3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KI2L3_HUMAN, P43628 (See
protein sequence)Recommended Name: Killer cell immunoglobulin-like receptor 2DL3 precursor Size: 341 amino acids; 37886 Da
Subunit: Interacts with ARRB2
Subcellular location: Cell membrane; Single-pass type I membrane protein
1 PDB 3D structure from  and Proteopedia  for KIR2DL3:1B6U (3D)
Secondary accessions: O43472 P78402 Q14944 Q14945 Q9UM51 Q9UQ70Alternative splicing: 2 isoforms: P43628-1 P43628-2 Explore the universe of human proteins at neXtProt for KIR2DL3: NX_P43628
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P43628
KIR2DL3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_056952.2
ENSEMBL proteins: ENSP00000342215 ENSP00000415758 Reactome Protein details: P43628
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
KIR2DL3 for ontologies About GeneDecksing
KIR2DL3 Antibody Products:
Assay Products for KIR2DL3: |
Protein
Domains /
Families
for KIR2DL3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KIR2DL3 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P43628ProtoNet protein and cluster: P43628 1 Blocks protein family: IPB003599 Immunoglobulin subtype
UniProtKB/Swiss-Prot: KI2L3_HUMAN, P43628Similarity: Belongs to the immunoglobulin superfamilySimilarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains |
Function
for KIR2DL3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KI2L3_HUMAN, P43628Function: Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activityof NK cells thus preventing cell lysis Genatlas biochemistry entry for KIR2DL3:natural killer cell immunoglobulin-like inhibitory receptor for HLA-C antigens,2DL3,58kDa
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIR2DL3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for KIR2DL3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIR2DL3 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
KIR2DL3 for ontologies About GeneDecksing
|
Pathways & Interactions
for KIR2DL3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Immune System | | | 2 | Allograft rejection | | | 3 | Immune response CD16 signaling in NK cells | | | 4 | Natural killer cell mediated cytotoxicity | | | 5 | Cleavage of Alpha-1-Microglobulin | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for KIR2DL3
1  GeneGo (Thomson Reuters) Pathway for KIR2DL3
3 
Reactome Pathways for KIR2DL3
3 
Kegg Pathways (Kegg details for KIR2DL3):
KIR2DL3 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KIR2DL3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/31 Interacting proteins for KIR2DL3 (P436282, 3 ENSP000003422154) via UniProtKB, MINT, STRING, and/or I2D (see all 31)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
KIR2DL3 for ontologies About GeneDecksing
|
Drugs & Compounds
for KIR2DL3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
KIR2DL3 for compounds About GeneDecksing
 Browse Tocris compounds for KIR2DL3
1 Novoseek chemical compound relationship for KIR2DL3 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tyrosine |
0 |
2 |
8574854 (2) |
Search CenterWatch for drugs/clinical trials and news about KIR2DL3 / KI2L3
|
Transcripts
for KIR2DL3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KIR2DL3 gene (2 alternative transcripts): NM_015868.2 NM_014511.3 Unigene Cluster for KIR2DL3: Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 Hs.731378 [show with all ESTs]Unigene Representative Sequence: BC0507302 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000342376(uc002qgx.3) ENST00000434419(uc010erw.1 uc002qgz.1 uc002qha.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIR2DL3
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIR2DL3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KIR2DL3 (NM_015868) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIR2DL3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIR2DL3 |
Additional cDNA sequence: AF022048.1 AF135565.1 AF135566.1 AF135567.1 AF285433.1 AF285435.1 AY789057.1 BC032422.1 BC050730.1 BC110613.1 FN395076.1 FN552550.1 L41268.1 L76662.1 L76663.1 U24074.1 U50546.1 U73395.1 U96190.1 4 DOTS entries: DT.95344548 DT.86840863 DT.100785352 DT.40115449 5 AceView cDNA sequences: BI909683 L41268 NM_153443 NM_014511 NM_014218
GeneLoc Exon Structure
|
Expression
for KIR2DL3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KIR2DL3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See KIR2DL3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KIR2DL3
SOURCE GeneReport for Unigene cluster: Hs.731378
SABiosciences Custom PCR Arrays for KIR2DL3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIR2DL3
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat KIR2DL3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIR2DL3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIR2DL3 |
Orthologs
for KIR2DL3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for KIR2DL3 gene from 2/5 species (see all 5) About this table
ENSEMBL Gene Tree for KIR2DL3 (if available)
TreeFam Gene Tree for KIR2DL3 (if available) |
Paralogs
for KIR2DL3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KIR2DL3 gene
- KIR2DL11 2 KIR2DL42 LILRB42 LILRB12 LILRA62 IGSF12 LILRA52 KIR3DL12
- OSCAR2 NCR12 LILRA42 ENSG000002177922 TARM12 KIR3DX12 LILRA32 LILRB52
- LILRA12 KIR3DL32 LILRB22 A1BG2 KIR2DL22 LILRA22 KIR3DL22 FCAR2
- LILRB32 GP62
18/54 SIMAP similar genes for KIR2DL3 using alignment to 12 protein entries: KI2L3_HUMAN (see all proteins)
(see all similar genes):KIR412 KIR2DL2 KIR-K36 KIR-G2 KIR-K9 KIR-K3
KIR-K65 KIR-K78 p58 KIR2DS2 KIR2DL1 KIR-K61
KIR2DS1 KIR221 KIR-K64 KIR2DS KIR-K15 KIR411
KIR2DL3 for paralogs About GeneDecksing
|
Genomic Variants
for KIR2DL3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KIR2DL3 (55249974 - 55295776 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 19 variations for KIR2DL3
15/19 CNVs (see all 19): 30924 50215 89325 73427 22912 8876 73425 0809 2248 4088 5117 73428 32271 3200 5345
Human Gene Mutation Database (HGMD): KIR2DL3
Locus Specific Mutation Databases (LSDB): KIR2DL3
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIR2DL3 |
|
Disorders
/ Diseases
for KIR2DL3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KIR2DL3 for disorders About GeneDecksing
OMIM gene information: 604938
OMIM disorders: --
20/59  diseases for KIR2DL3 (see all 59): About MalaCardsvogt-koyanagi-harada disease large granular lymphocyte leukemia t-cell large granular lymphocyte leukemia tropical spastic paraparesis
graft versus host disease spastic paraparesis familial mediterranean fever non-hodgkin lymphoma
cervical intraepithelial neoplasia anterior uveitis spontaneous abortion ankylosing spondylitis
systemic lupus erythematosus lymphocytic leukemia t-lymphocytopenia lupus erythematosus
hodgkin's lymphoma inflammatory bowel disease psoriatic arthritis spasticity
4 Novoseek disease relationships for KIR2DL3 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| lymphoma t-cell |
39.4 |
2 |
11253136 (1) |
| psoriasis |
27.2 |
1 |
16882169 (1) |
| hepatitis c |
10.7 |
1 |
20077564 (1) |
| hiv infections |
0 |
1 |
10229073 (1) |
Genetic Association Database (GAD): KIR2DL3
Human Genome Epidemiology (HuGE) Navigator: KIR2DL3 (108 documents)
Export disorders for KIR2DL3 gene to outside databases
|
Publications
for KIR2DL3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KIR2DL3 gene, integrated from 9 sources (see all 209):
(articles sorted by number of sources associating them with KIR2DL3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Alternatively spliced forms of human killer inhibitory receptors. (PubMed id 8662091)1, 2, 3 Dohring C....Colonna M. (1996)
- Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. (PubMed id 7749980)1, 2, 3 Wagtmann N....Long E.O. (1995)
- Crystal structure of the human p58 killer cell inhibitory receptor (KIR2DL3) specific for HLA-Cw3-related MHC class I. (PubMed id 10196125)1, 2, 9 Maenaka K.... Jones E.Y. (1999)
- Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. (PubMed id 7716543)1, 2, 9 Colonna M. and Samaridis J. (1995)
- An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cells. (PubMed id 18604210)1, 2 Yu M.-C.... Ge B.-X. (2008)
- Comparison of killer Ig-like receptor genotyping and phenotyping for selection of allogeneic blood stem cell donors. (PubMed id 15879158)1, 4 Leung W....Handgretinger R. (2005)
- Activating killer cell immunoglobulin-like receptor gene KIR2DS1 is associated with psoriatic arthritis. (PubMed id 16112031)1, 4 Williams F....Middleton D. (2005)
- A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia. (PubMed id 15730517)1, 4 Arnheim L....Sanjeevi C.B. (2005)
- Genetic polymorphism of NK receptors and their ligands in melanoma patients: prevalence of inhibitory over activating signals. (PubMed id 15248031)1, 4 Naumova E....Toneva M. (2005)
- Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population. (PubMed id 15896204)1, 4 Jiang K....Yan L.X. (2005)
|
External Searches for KIR2DL3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KIR2DL3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KIR2DL3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KIR2DL3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KIR2DL3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KIR2DL3 gene:
Search GeneIP for patents involving KIR2DL3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIR2DL3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KIR2DL3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KIR2DL3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIR2DL3 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KIR2DL3 | | OriGene 3'-UTR Clone for KIR2DL3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIR2DL3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIR2DL3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIR2DL3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIR2DL3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIR2DL3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIR2DL3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIR2DL3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIR2DL3 |
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| | | | Search Tocris compounds for KIR2DL3 |
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 | | | KIR2DL3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | ThermoFisher Antibodies for KIR2DL3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIR2DL3 |
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