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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KIR2DL1 Gene

protein-coding   GIFtS: 62
GCID: GC19P055283

killer cell immunoglobulin-like receptor, two domains, long...
 Explore 54 diseases affiliated with
KIR2DL1 via
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Biological research products
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Aliases
for KIR2DL1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic
Tail, 11 2
     Cl-421
CD158A1 2 3     Nkat11
NKAT12 3 5     KIR-K642
P58.11     KIR2212
Natural Killer-Associated Transcript 12 3     NKAT2
NKAT-12 3     Killer Cell Immunoglobulin-Like Receptor 2DL12
CD158 Antigen-Like Family Member A2 3     Killer Ig Receptor2
MHC Class I NK Cell Receptor2 3     Killer Inhibitory Receptor 2-2-12
P58 Natural Killer Cell Receptor Clones CL-42/47.112 3     P58 Killer Cell Inhibitory Receptor KIR-K642
P58 NK Receptor CL-42/47.112 3     P58 NK Cell Inhibitory Receptor NKR-K62
P58.1 MHC Class-I-Specific NK Receptor2 3     CD158a Antigen3
47.111     

External Ids:    HGNC: 63291   Entrez Gene: 38022   Ensembl: ENSG000001254987   OMIM: 6049365   UniProtKB: P436263   

Export aliases for KIR2DL1 gene to outside databases

Previous GC identifers: GC19P056112 GC19P055660 GC19P059720 GC19P059736 GC19P059974 GC19P059975 GC19P059938 GC19P059980 GC19P059983 GC19P055282


Summaries
for KIR2DL1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for KIR2DL1:
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and
subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome
19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among
haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The
KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have
a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals
upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short
cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to
transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR
proteins are thought to play an important role in regulation of the immune response. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: KI2L1_HUMAN, P43626
Function: Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing
cell lysis

Gene Wiki entry for KIR2DL1


Genomic Views
for KIR2DL1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KIR2DL1 gene promoter:
         RORalpha1   GATA-3   Pax-2   Pax-2a   GATA-1   GATA-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: KIR2DL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for KIR2DL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIR2DL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.4   Ensembl cytogenetic band:  19q13.42   HGNC cytogenetic band: 19q13.4

KIR2DL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIR2DL1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P055283:  view genomic region     (about GC identifiers)

Start:
 55,281,263 bp from pter      End:
 55,295,778 bp from pter
Size:
 14,516 bases      Orientation:
 plus strand

Proteins
for KIR2DL1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: KI2L1_HUMAN, P43626 (See protein sequence)
Recommended Name: Killer cell immunoglobulin-like receptor 2DL1 precursor  
Size: 348 amino acids; 38505 Da
Subunit: Interacts with ARRB2. Interacts with PTPN6; the interaction is enhanced by ARRB2. Interacts with PTPN11; the
interaction is enhanced by ARRB2
Subcellular location: Cell membrane; Single-pass type I membrane protein
2 PDB 3D structures from and Proteopedia for KIR2DL1:
1IM9 (3D)        1NKR (3D)    
Secondary accessions: O43470 Q32WE6

Explore the universe of human proteins at neXtProt for KIR2DL1: NX_P43626

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P43626

    • KIR2DL1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_055033.2  
    ENSEMBL proteins: 
     ENSP00000336769   ENSP00000291633  
    Reactome Protein details: P43626
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    ProSpec Recombinant Protein for KIR2DL1
    Uscn Proteins for KIR2DL1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane TAS7749980


    KIR2DL1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for KIR2DL1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    KIR2DL1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR013783 Ig-like_fold
     IPR003599 Ig_sub
     IPR013151 Immunoglobulin

    Graphical View of Domain Structure for InterPro Entry P43626

    ProtoNet protein and cluster: P43626

    1 Blocks protein family: IPB003599 Immunoglobulin subtype

    UniProtKB/Swiss-Prot: KI2L1_HUMAN, P43626
    Similarity: Belongs to the immunoglobulin superfamily
    Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains


    Function
    for KIR2DL1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: KI2L1_HUMAN, P43626
    Function: Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing
    cell lysis

         Genatlas biochemistry entry for KIR2DL1:
    natural killer cell immunoglobulin-like inhibitory receptor for HLA-C antigen,2DL1,58kDa

    miRNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872receptor activity TAS7749980
    GO:0005515protein binding IPI18604210


    KIR2DL1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for KIR2DL1:
     Increased G1 DNA content 


    Pathways & Interactions
    for KIR2DL1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Immune System
    		Immune System1.00
    		Adaptive Immune System0.59
    2Allograft rejection
    		Graft-versus-host disease0.63
    		Antigen processing and presentation0.25
    3Immune response CD16 signaling in NK cells
    		Immune response Role of DAP12 receptors in NK cells0.32
    		Immune response_Role of DAP12 receptors in NK cells0.32
    4Natural killer cell mediated cytotoxicity
    		Natural killer cell mediated cytotoxicity1.00
    5Cleavage of Alpha-1-Microglobulin
    		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell0.30

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for KIR2DL1
        Immune response Role of DAP12 receptors in NK cells


    1 GeneGo (Thomson Reuters) Pathway for KIR2DL1
        Immune response Role of DAP12 receptors in NK cells

    3        Reactome Pathways for KIR2DL1
        Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
    Adaptive Immune System
    Immune System


    3         Kegg Pathways  (Kegg details for KIR2DL1):
        Antigen processing and presentation
    Natural killer cell mediated cytotoxicity
    Graft-versus-host disease


    KIR2DL1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KIR2DL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/12 Interacting proteins for KIR2DL1 (P436262, 3 ENSP000003367694) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PTPN6P293502, 3, ENSP000003915924MINT-8035707 MINT-8035722 MINT-8027477 MINT-8027492 I2D: score=2 STRING: ENSP00000391592
    PTPN11Q061242, 3, ENSP000003409444MINT-8027537 MINT-8027552 I2D: score=2 STRING: ENSP00000340944
    PIK3R1P279862, 3, ENSP000002743354MINT-8027522 MINT-8027507 I2D: score=1 STRING: ENSP00000274335
    HLA-CP103213, ENSP000003654024I2D: score=3 STRING: ENSP00000365402
    ARRB2P321213I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002769natural killer cell inhibitory signaling pathway IDA18604210
    GO:0006955immune response TAS7749980
    GO:0050776regulation of immune response TAS--


    KIR2DL1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for KIR2DL1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    KIR2DL1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for KIR2DL1
    2 Novoseek chemical compound relationships for KIR2DL1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lipid 0 3 11724921 (1), 12351398 (1)
    tyrosine 0 2 11034353 (1), 12351398 (1)

    Search CenterWatch for drugs/clinical trials and news about KIR2DL1 / KI2L1 

    Transcripts
    for KIR2DL1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for KIR2DL1 gene: 
    NM_014218.2  

    Unigene Clusters for KIR2DL1:

    Killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
    Hs.654605  [show with all ESTs], Hs.690615
    Unigene Representative Sequences: X93595, AJ630586
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000336077(uc010erz.1 uc002qhb.1) ENST00000291633

    miRNA
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AJ630586.1 U96189.1 XR_159106.1 

    4 DOTS entries:

    DT.92058638  DT.86840863  DT.121450410  DT.95344548 

    5 AceView cDNA sequences:

    NM_153443 L41268 BI909683 NM_014511 NM_014218 

    GeneLoc Exon Structure


    Expression
    for KIR2DL1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KIR2DL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    KIR2DL1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Natural killer-like cells (Derivation of hemato...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See KIR2DL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KIR2DL1

    SOURCE GeneReport for Unigene clusters: Hs.654605 Hs.690615
        SABiosciences Custom PCR Arrays for KIR2DL1
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    In Situ
    Assay Products:     
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    Orthologs
    for KIR2DL1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for KIR2DL1 gene from 2/5 species (see all 5)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves --
    GGA.298836
    (see all 59)    		 --
    		 23(a)
    21(a)
    (see all 59)    		 many ↔ many
    many ↔ many
    (see all 59)    		 Un(51843257-51844123)
    Un(8554156-8556166)
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    (see all 3)    		 --
    		 9(a)
    17(a)
    (see all 3)    		 many ↔ many
    many ↔ many
    (see all 3)    		 GL343329.1(1200149-1218701)
    GL343329.1(1231914-1234163)


    ENSEMBL Gene Tree for KIR2DL1 (if available)
    TreeFam Gene Tree for KIR2DL1 (if available) 

    Paralogs
    for KIR2DL1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KIR2DL1 gene
    KIR2DL31 2  KIR2DL42  LILRB42  LILRB12  LILRA62  IGSF12  LILRA52  KIR3DL12  
    OSCAR2  NCR12  LILRA42  ENSG000002177922  TARM12  KIR3DX12  LILRA32  LILRB52  
    LILRA12  KIR3DL32  LILRB22  A1BG2  KIR2DL22  LILRA22  KIR3DL22  FCAR2  
    LILRB32  GP62  
    18/53 SIMAP similar genes for KIR2DL1 using alignment to 20 protein entries:     KI2L1_HUMAN (see all proteins) (see all similar genes):
    KIR-K3    KIR-K64    KIR-G2    KIR-K9    KIR2DL2    KIR2DS1
    KIR-K61    KIR-K65    KIR412    KIR2DL3    KIR-K78    KIR-K15
    KIR221    KIR-K36    p58    KIR2DS    KIR2DS2    KIR2DS4

    KIR2DL1 for paralogs           About GeneDecksing



    Genomic Variants
    for KIR2DL1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/417 NCBI SNPs in KIR2DL1 are shown (see all 417)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1867516351,2
    		--55279335(+) TCATGG/TTTTCG 1 -- us2k10--------
    rs106705091,2
    		C,--55279373(+) TTCCA-/GTGTTATC 5 -- us2k1 ds50010--------
    rs1905933971,2
    		--55279373(+) CTTCCA/GTTATC 1 -- us2k10--------
    rs1831512061,2
    		--55279399(+) TAACCA/CCATCT 1 -- us2k10--------
    rs28863211,2
    		C,--55279428(+) ACCCCC/TGGACT 4 -- us2k11Minor allele frequency- T:0.00NA 2
    rs1445817991,2
    		--55279442(+) AGTTTC/GTGGAA 1 -- us2k10--------
    rs1863612891,2
    		--55279510(+) ATAGGA/CGGTTC 1 -- us2k10--------
    rs1484081081,2
    		--55279525(+) GATCGG/TGAATC 1 -- us2k10--------
    rs1425247971,2
    		--55279601(+) AACATC/TTGTAG 1 -- us2k10--------
    rs81039881,2
    		C,F,A,--55279608(+) GTAGAG/ATCATA 4 -- us2k13Minor allele frequency- A:0.40NA CSA 5

    HapMap Linkage Disequilibrium report for KIR2DL1 (55281263 - 55295778 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 19 variations for KIR2DL1
         15/19 CNVs (see all 19): 30924 50215 89325 73427 22912 8876 73425 0809 73431 2248 4088 5117 32271 3200 61721
    Human Gene Mutation Database (HGMD): KIR2DL1

    Locus Specific Mutation Databases (LSDB): KIR2DL1

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    Disorders / Diseases
    for KIR2DL1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    KIR2DL1 for disorders           About GeneDecksing

    OMIM gene information: 604936    OMIM disorders: --

    20/54 diseases for KIR2DL1 (see all 54):    About MalaCards
    vogt-koyanagi-harada disease    large granular lymphocyte leukemia    birdshot chorioretinopathy    t-cell large granular lymphocyte leukemia
    tropical spastic paraparesis    microscopic polyangiitis    graft versus host disease    spastic paraparesis
    familial mediterranean fever    non-hodgkin lymphoma    cervical intraepithelial neoplasia    anterior uveitis
    spontaneous abortion    ankylosing spondylitis    systemic lupus erythematosus    lymphocytic leukemia
    behcet's disease    lupus erythematosus    hodgkin's lymphoma    inflammatory bowel disease

    6 Novoseek disease relationships for KIR2DL1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lymphoma t-cell 40.6 3 11253136 (2)
    behcet disease 27.6 1 11229470 (1)
    autoimmune diseases 0 3 11229470 (2)
    rheumatoid arthritis 0 1 11229470 (1)
    tumors 0 4 11724921 (1), 15312339 (1), 12351398 (1)
    melanoma 0 1 16914567 (1)

    Genetic Association Database (GAD): KIR2DL1
    Human Genome Epidemiology (HuGE) Navigator: KIR2DL1 (103 documents)

    Export disorders for KIR2DL1 gene to outside databases

    Publications
    for KIR2DL1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KIR2DL1 gene, integrated from 9 sources (see all 193):
    (articles sorted by number of sources associating them with KIR2DL1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. (PubMed id 7749980)1, 2, 3 Wagtmann N....Long E.O. (1995)
    2. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. (PubMed id 7716543)1, 2, 3 Colonna M. and Samaridis J. (1995)
    3. Comparison of killer Ig-like receptor genotyping and phenotyping for selection of allogeneic blood stem cell donors. (PubMed id 15879158)1, 4, 9 Leung W....Handgretinger R. (2005)
    4. An essential function for beta-arrestin 2 in the inhibitory signaling of natural killer cells. (PubMed id 18604210)1, 2 Yu M.-C.... Ge B.-X. (2008)
    5. Activating killer cell immunoglobulin-like receptor gene KIR2DS1 is associated with psoriatic arthritis. (PubMed id 16112031)1, 4 Williams F....Middleton D. (2005)
    6. A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia. (PubMed id 15730517)1, 4 Arnheim L....Sanjeevi C.B. (2005)
    7. Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population. (PubMed id 15896204)1, 4 Jiang K....Yan L.X. (2005)
    8. Gene for the activating natural killer cell receptor, KIR2DS1, is associated with susceptibility to psoriasis vulgaris. (PubMed id 15310528)1, 4 L/uszczek W....Kusnierczyk P. (2004)
    9. Distinctive KIR and HLA diversity in a panel of north Indian Hindus. (PubMed id 11904677)1, 4 Rajalingam R....Parham P. (2002)
    10. Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters. (PubMed id 12121272)1, 4 Moodie S.J....Ciclitira P.J. (2002)

    External Searches for KIR2DL1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing KIR2DL1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3802 HGNC: 6329 AceView: KIR2DL1 Ensembl:ENSG00000125498 euGenes: HUgn3802
    ECgene: KIR2DL1 Kegg: 3802 H-InvDB: KIR2DL1

    Other Databases showing KIR2DL1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing KIR2DL1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KIR2DL1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for KIR2DL1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for KIR2DL1 gene:
    Search GeneIP for patents involving KIR2DL1

    GeneCards and IP:
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