KIF7 Gene
protein-coding GIFtS: 49
GCID: GC15M090171
|
|
kinesin family member 7
| |
Aliases
for KIF7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Kinesin Family Member 71 2 | | HLS22 | | JBTS121 2 | | UNQ3402 | | ACLS2 | | Kinesin-Like Protein KIF72 | | EQYK3402 | | |
Export aliases for KIF7 gene to outside databasesPrevious GC identifers: GC15M087973 GC15M066284 |
Summaries
for KIF7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KIF7:
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonichedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negativeregulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as apositive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have beenassociated with various ciliopathies. (provided by RefSeq, Oct 2011)
UniProtKB/Swiss-Prot: KIF7_HUMAN, Q2M1P5Function: Acts as both a negative and positive regulator of sonic hedgehog (Shh) pathway, acting downstream of SMO.Negatively regulates the pathway by preventing inappropriate activation of the transcriptional activator GLI2 in theabsence of ligand. Positively regulates the pathway by preventing the processing of the transcription factor GLI3 intoits repressor form. Required for efficient localization of GLI3 to cilia in response to Shh. Affects microtubulardynamics and acts as a ciliary motor
|
Genomic Views
for KIF7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010274.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIF7 gene promoter:
ER-alpha Pax-5 Lmo2 CUTL1 AP-4 LCR-F1 Nkx5-1 C/EBPalpha Ik-2 HOXA5
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIF7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIF7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q26.1 Ensembl cytogenetic band: 15q26.1 HGNC cytogenetic band: 15q26.1KIF7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M090171: view genomic region
(about GC identifiers)
Start:
|
90,152,020 bp from pter |
End:
|
90,198,682 bp from pter |
Size:
|
46,663 bases |
Orientation:
|
minus strand |
|
Proteins
for KIF7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KIF7_HUMAN, Q2M1P5 (See
protein sequence)Recommended Name: Kinesin-like protein KIF7 Size: 1343 amino acids; 150587 Da
Subunit: Interacts with GLI1, GLI2, GLI3, SMO and SUFU. Interacts with NPHP1
Subcellular location: Cell projection, cilium. Note=SMO is required for its accumulation within cilia. Moves from thecilia base to the cilia tip in response to activation of the Shh pathway
Sequence caution: Sequence=AAI04045.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAI12272.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAI12274.1;Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAQ88750.1; Type=Erroneous initiation;Note=Translation N-terminally extended;
2 PDB 3D structures from  and Proteopedia  for KIF7:2XT3 (3D)
4A14 (3D)
Secondary accessions: Q3SXY0 Q6UXE9 Q8IW72Explore the universe of human proteins at neXtProt for KIF7: NX_Q2M1P5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q2M1P5
KIF7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_940927.2
ENSEMBL proteins: ENSP00000377934 ENSP00000395906
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
KIF7 for ontologies About GeneDecksing
KIF7 Antibody Products:
Assay Products for KIF7: |
Protein
Domains /
Families
for KIF7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KIF7 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q2M1P5ProtoNet protein and cluster: Q2M1P5 UniProtKB/Swiss-Prot: KIF7_HUMAN, Q2M1P5Similarity: Belongs to the kinesin-like protein family. KIF27 subfamilySimilarity: Contains 1 kinesin-motor domain |
Function
for KIF7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KIF7_HUMAN, Q2M1P5Function: Acts as both a negative and positive regulator of sonic hedgehog (Shh) pathway, acting downstream of SMO.Negatively regulates the pathway by preventing inappropriate activation of the transcriptional activator GLI2 in theabsence of ligand. Positively regulates the pathway by preventing the processing of the transcription factor GLI3 intoits repressor form. Required for efficient localization of GLI3 to cilia in response to Shh. Affects microtubulardynamics and acts as a ciliary motor
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIF7 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF7 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
KIF7 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for KIF7:
Animal Models:
Mouse knock-out Kif7tm1.2Hui for KIF7
9 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Kif7):
KIF7 for phenotypes About GeneDecksing
|
Pathways & Interactions
for KIF7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIF7
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
5/8 Interacting proteins for KIF7 (Q2M1P52, 3 ENSP000003779344) via UniProtKB, MINT, STRING, and/or I2D (see all 8)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007018 | microtubule-based movement |
IEA | -- | | GO:0045879 | negative regulation of smoothened signaling pathway |
ISS | -- | | GO:0045880 | positive regulation of smoothened signaling pathway |
ISS | -- |
KIF7 for ontologies About GeneDecksing
|
Drugs & Compounds
for KIF7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KIF7
Search CenterWatch for drugs/clinical trials and news about KIF7
|
Transcripts
for KIF7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KIF7 gene: NM_198525.2 Unigene Cluster for KIF7: Kinesin family member 7 Hs.513134 [show with all ESTs]Unigene Representative Sequence: NM_1985253 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000558928 ENST00000394412(uc010upw.1 uc002bof.2 uc002bog.2)
ENST00000445906
Clone
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OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KIF7 (NM_198525) | | | DNA2.0 Custom Codon Optimized Gene
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Additional cDNA sequence: AY358384.1 BC040878.1 BC042063.1 BC104044.1 BC112271.1 BC112273.1 BC143461.1 3 DOTS entries: DT.105136 DT.97814905 DT.100742327 24/53 AceView cDNA sequences (see all 53): AI366107 AW451733 BM664985 NM_198525 BM853717 BQ683811 AY358384 CB265347 AI469074 BQ896998 BF515033 AI460357 BU157851 BM740890 AI493415 BG986359 AI884651 BX330907 BM744569 BC040878 BM743264 BF979906 BU194402 BM547456
GeneLoc Exon Structure
|
Expression
for KIF7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KIF7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGCTGTGGT
About this image
See KIF7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KIF7
SOURCE GeneReport for Unigene cluster: Hs.513134
UniProtKB/Swiss-Prot: KIF7_HUMAN, Q2M1P5Tissue specificity: Embryonic stem cells, melanotic melanoma and Jurkat T-cells. Expressed in heart, lung, liver,kidney, testis, retina, placenta, pancreas, colon, small intestin, prostate and thymus
SABiosciences Custom PCR Arrays for KIF7
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIF7
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF7 |
Orthologs
for KIF7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for KIF7 gene from 4/19 species (see all 19) About this table
ENSEMBL Gene Tree for KIF7 (if available)
TreeFam Gene Tree for KIF7 (if available) |
Paralogs
for KIF7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KIF7 gene
- KIF5C2 KIF21A2 KIF112 KIF3B2 KIF21B2 KIF92 KIF172 KIF4B2
- KIF272 KIF3A2 KIF4A2 KIF5B2 KIF62 KIF152 CENPE2 KIF5A2
- KIF3C2
6 SIMAP similar genes for KIF7 using alignment to 3 protein entries: KIF7_HUMAN (see all proteins):KIF27 KIF21A KIF3A KIF5C KIF3C KIF25
KIF7 for paralogs About GeneDecksing
|
Genomic Variants
for KIF7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KIF7 (90152020 - 90198682 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for KIF7
5 CNVs: 47910 87837 87836 77065 49618
Human Gene Mutation Database (HGMD): KIF7
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIF7 |
|
Disorders
/ Diseases
for KIF7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KIF7 for disorders About GeneDecksing
OMIM gene information: 611254
OMIM disorders: --
UniProtKB/Swiss-Prot: KIF7_HUMAN, Q2M1P5
Note=Ciliary dysfunction leads to a broad spectrum of disorders, collectively termed ciliopathies. Theciliopathy range of diseases includes Meckel-Gruber syndrome, Bardet-Biedl syndrome, Joubert syndrome, andhydrolethalus syndrome among others. Single-locus allelism is insufficient to explain the variable penetrance andexpressivity of such disorders, leading to the suggestion that variations across multiple sites of the ciliaryproteome influence the clinical outcome. Primary ciliopathy loci can be modulated by pathogenic lesions in otherciliary genes to either exacerbate overall severity or induce specific endophenotypes. KIF7 may be causally associatedwith diverse ciliopathies, and also acts as a modifier gene across the ciliopathy spectrum Defects in KIF7 may be a cause of Bardet-Biedl syndrome (BBS) [MIM:209900]. A syndrome characterized byusually severe pigmentary retinopathy, early-onset obesity, polydactyly, hypogenitalism, renal malformation and mentalretardation. Secondary features include diabetes mellitus, hypertension and congenital heart disease. Bardet-Biedlsyndrome inheritance is autosomal recessive, but three mutated alleles (two at one locus, and a third at a secondlocus) may be required for clinical manifestation of some forms of the disease. Note=Heterozygous missense mutationsin KIF7 may genetically interact with other BBS genes and contribute to disease manifestation and severity Defects in KIF7 are the cause of hydrolethalus syndrome type 2 (HLS2) [MIM:614120]. HLS2 is an embryoniclethal disorder characterized by hydrocephaly or anencephaly, postaxial polydactyly of the upper limbs, and pre- orpostaxial polydactyly of the lower limbs. Duplication of the hallux is a common finding Defects in KIF7 are the cause of acrocallosal syndrome (ACLS) [MIM:200990]. ACLS is a syndrome that ischaracterized by postaxial polydactyly, hallux duplication, macrocephaly and absence of the corpus callosum, usuallywith severe developmental delay Defects in KIF7 are the cause of Joubert syndrome type 12 (JBTS12) [MIM:200990]. JBTS12 is a disorderpresenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotordelay. Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reorientedsuperior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar toothon transaxial slices (molar tooth sign). Additional variable features include retinal dystrophy and renal disease Defects in KIF7 may be a cause of Pallister-Hall syndrome (PHS) [MIM:146510]. An autosomal dominant disordercharacterized by a wide range of clinical manifestations. Clinical features include hypothalamic hamartoma, pituitarydysfunction, central or postaxial polydactyly, and syndactyly. Malformations are frequent in the viscera, e.g. analatresia, bifid uvula, congenital heart malformations, pulmonary or renal dysplasia
20/23  diseases for KIF7 (see all 23): About MalaCardssmith-lemli-opitz syndrome rubinstein-taybi syndrome pallister-hall syndrome oculomotor apraxia
bardet-biedl syndrome nevoid basal cell carcinoma syndrome hypothalamic hamartomas apraxia
hydrolethalus syndrome corpus callosum pigmentary retinopathy acrocallosal syndrome
anencephaly joubert syndrome cerebellar ataxia basal cell carcinoma
syndactyly polydactyly ataxia hypotonia
1 disease from the University of Copenhagen DISEASES database for KIF7:Acrocallosal syndrome Export disorders for KIF7 gene to outside databases
|
Publications
for KIF7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KIF7 gene, integrated from 9 sources (see all 24):
(articles sorted by number of sources associating them with KIF7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of KIF7 gene in silico. (PubMed id 15547730)1, 2, 3 Katoh Y. and Katoh M. (2004)
- Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics. (PubMed id 21633164)1, 2 Dafinger C.... Bolz H.J. (2011)
- KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes. (PubMed id 21552264)1, 2 Putoux A.... Attie-Bitach T. (2011)
- The mammalian Cos2 homolog Kif7 plays an essential ro le in modulating Hh signal transduction during development. (PubMed id 19592253)1, 2 Endoh-Yamagami S....Peterson A.S. (2009)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- All kinesin superfamily protein, KIF, genes in mouse and human. (PubMed id 11416179)1, 3 Miki H....Hirokawa N. (2001)
- Structural insights into human Kif7, a kinesin involve d in Hedgehog signalling. (PubMed id 22281744)1 Klejnot M. and Kozielski F. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for KIF7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KIF7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KIF7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing KIF7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KIF7 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for KIF7 gene:
Search GeneIP for patents involving KIF7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIF7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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variant library, vector shuttling | | | OriGene Custom Antibody Services for KIF7 | | OriGene Custom Protein Services for KIF7 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIF7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIF7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIF7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIF7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIF7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIF7 |
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| |  |  |  |  | | | | |
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 | | | KIF7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF7 |
|  |  |  | | | | Search ThermoFisher Antibodies for KIF7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIF7 |
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