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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KIF6 Gene

protein-coding   GIFtS: 55
GCID: GC06M039297

Kinesin Family Member 6

(Previous name: chromosome 6 open reading frame 102)
(Previous symbol: C6orf102)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Kinesin Family Member 61 2     dJ137F1.42
C6orf1021 2 3     dJ188D3.12
Chromosome 6 Open Reading Frame 1021     Kinesin-Like Protein KIF62
dJ1043E3.12     

External Ids:    HGNC: 212021   Entrez Gene: 2214582   Ensembl: ENSG000001646277   OMIM: 6139195   UniProtKB: Q6ZMV93   

Export aliases for KIF6 gene to outside databases

Previous GC identifers: GC00U914198 GC06U900645 GC06M039412 GC06M039021


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for KIF6 Gene: 
KIF6 (kinesin family member 6) is a protein-coding gene. Diseases associated with KIF6 include coronary heart disease, and ischemic heart disease. GO annotations related to this gene include microtubule motor activity and ATP binding. An important paralog of this gene is KIF9.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007592.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KIF6 gene promoter:
         RP58   AML1a   ATF-2   Pax-2   Pax-2a   HNF-1A   S8   Pax-2b   HNF-1   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKIF6 promoter sequence
   Search SABiosciences Chromatin IP Primers for KIF6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIF6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.2   Ensembl cytogenetic band:  6p21.2   HGNC cytogenetic band: 6p21.2

KIF6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIF6 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M039297:  view genomic region     (about GC identifiers)

Start:
39,297,766 bp from pter      End:
39,693,181 bp from pter
Size:
395,416 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KIF6_HUMAN, Q6ZMV9 (See protein sequence)
Recommended Name: Kinesin-like protein KIF6  
Size: 814 amino acids; 92569 Da
Subcellular location: Cytoplasm, cytoskeleton (Probable)
Secondary accessions: Q2MDE3 Q2MDE4 Q5T8J6 Q6ZWE3 Q86T87 Q8WTV4
Alternative splicing: 4 isoforms:  Q6ZMV9-1   Q6ZMV9-2   Q6ZMV9-3   Q6ZMV9-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KIF6: NX_Q6ZMV9

Explore proteomics data for KIF6 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6ZMV9

  • KIF6 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KIF6 Protein Expression
    REFSEQ proteins: NP_659464.3  
    ENSEMBL proteins: 
     ENSP00000409417   ENSP00000287152   ENSP00000377889   ENSP00000229913   ENSP00000404856  
     ENSP00000362312   ENSP00000362311   ENSP00000441435   ENSP00000362309   ENSP00000439064  

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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for KIF6 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005871kinesin complex IEA--
    GO:0005874microtubule IEA--
    GO:0005875microtubule associated complex ----

    KIF6 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    KIF: Kinesins

    3 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR001752 Kinesin_motor_dom
     IPR019821 Kinesin_motor_CS

    Graphical View of Domain Structure for InterPro Entry Q6ZMV9

    ProtoNet protein and cluster: Q6ZMV9

    1 Blocks protein domain: IPB001752 Kinesin

    UniProtKB/Swiss-Prot: KIF6_HUMAN, Q6ZMV9
    Similarity: Belongs to the kinesin-like protein family
    Similarity: Contains 1 kinesin-motor domain


    KIF6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003777microtubule motor activity IEA--
    GO:0005515protein binding IPI16189514
    GO:0005524ATP binding IEA--
    GO:0008017microtubule binding IEA--
         
    KIF6 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for KIF6:
     Increased cell number in G2M,   Metaphase cells 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for KIF6 
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate KIF6:
    hsa-miR-708 hsa-miR-3130-5p hsa-miR-28-5p hsa-miR-452* hsa-miR-3139 hsa-miR-3160-3p
    SwitchGear 3'UTR luciferase reporter plasmidKIF6 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF6


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIF6

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for KIF6 (Q6ZMV91, 2, 3 ENSP000002871524) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APPBP2Q926241, 2, 3, ENSP000000831824EBI-751100,EBI-743771 MINT-68019 I2D: score=4 STRING: ENSP00000083182
    SIRT5ENSP000003685524STRING: ENSP00000368552
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007018microtubule-based movement IEA--

    KIF6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    KIF6 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KIF6

    2 PharmGKB related drug/compound annotations for KIF6 gene    About this table
    Drug/compound PharmGKB Annotation
    atorvastatinCA  
    pravastatinCA  

    Search CenterWatch for drugs/clinical trials and news about KIF6

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KIF6 gene: 
    NM_145027.4  

    Unigene Cluster for KIF6:

    Kinesin family member 6
    Hs.588202  [show with all ESTs]
    Unigene Representative Sequence: NM_145027
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000458470 ENST00000287152(uc003oot.2 uc011dua.1 uc010jxb.1)
    ENST00000394362(uc003oos.2) ENST00000229913 ENST00000441975 ENST00000482238
    ENST00000465719(uc003oou.3) ENST00000373216(uc010jxa.1) ENST00000373215
    ENST00000538893 ENST00000373213(uc010jwz.1) ENST00000541946
    miRNA
    Products:
         
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate KIF6:
    hsa-miR-708 hsa-miR-3130-5p hsa-miR-28-5p hsa-miR-452* hsa-miR-3139 hsa-miR-3160-3p
    SwitchGear 3'UTR luciferase reporter plasmidKIF6 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIF6
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIF6

    Additional mRNA sequence: 

    AK131471.1 BC022074.2 BC043552.1 BC098418.1 BC117307.1 BC143444.1 BC143445.1 BX649045.1 

    11 DOTS entries:

    DT.99930082  DT.97822241  DT.91679693  DT.101960199  DT.40244026  DT.40287381  DT.95187832  DT.429768 
    DT.100666855  DT.40307652  DT.75191915 

    39 AceView cDNA sequences (see top 24):

    AL041547 BC022074 AI352520 BX111141 BC043552 BF057276 BX106415 BX649045 
    AI168595 BX114379 BE223014 BE858267 AL832634 AI026880 CA314029 BI118088 
    BG189781 AA705330 BM667910 NM_145027 BX499296 AI222076 AK131471 BM696570 
    AK097521 BG199894 AK123217 AI693047 BE044185 BG715118 AA002212 BI818442 
    BM696555 CD684245 T19133 BM042034 AI807106 AA002057 BE044222 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for KIF6 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b · 16c · 16d ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a ·
    SP1:              -           -                                                                             -     -     -                                       
    SP2:                                                                                                        -     -     -                                       
    SP3:                                                                                                        -     -     -     -                                 
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 21b ^ 22a · 22b ^ 23 ^ 24 ^ 25 ^ 26a · 26b
    SP1:                                -               
    SP2:        -     -                 -               
    SP3:                                -               
    SP4:                                                
    SP5:                                -               


    ECgene alternative splicing isoforms for KIF6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KIF6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACGGTCCCA
    KIF6 Expression
    About this image


    See KIF6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KIF6

    SOURCE GeneReport for Unigene cluster: Hs.588202
        SABiosciences Custom PCR Arrays for KIF6
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for KIF6 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kif61 , 5 kinesin family member 61, 5 81.59(n)1
    83.42(a)1
      17 (25.78 cM)5
    3199911  NM_177052.31  NP_796026.21 
     496151365 
    chicken
    (Gallus gallus)
    Aves KIF61 kinesin family member 6 74.15(n)
    76.94(a)
      428572  XM_003640945.1  XP_003640993.1 
    lizard
    (Anolis carolinensis)
    Reptilia KIF66
    kinesin family member 6
    66(a)
    1 ↔ 1
    1(246699317-246901752)
    zebrafish
    (Danio rerio)
    Actinopterygii kif61 kinesin family member 6 59.92(n)
    58.33(a)
      553436  NM_001077431.1  NP_001070899.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SMY16
    Protein that interacts with Myo2p, proposed to be ...
    14(a)
    1 → many
    XI(286603-288573)


    ENSEMBL Gene Tree for KIF6 (if available)
    TreeFam Gene Tree for KIF6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KIF6 gene
    KIF92  
    18/44 SIMAP similar genes for KIF6 using alignment to 11 protein entries:     KIF6_HUMAN (see all proteins) (see all similar genes):
    KIFC3    KIF13A    KIF18A    KIF18B    A20    KIF17
    KIF5B-ALK    KLP6    R11    R12    KIF9    KIF15
    KIF5C    KIF12    KIF1A    KIF1Bbeta    KIF5B    KIF13B

    KIF6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/7519 SNPs in KIF6 are shown (see all 7519)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0362174
    A breast cancer sample4--see VAR_0362172 A E mis40--------
    rs1889877201,2
    C--39302425(+) GAAAAG/TAAAAG 1 -- ds50010--------
    rs77740461,2
    C,F,A,H--39302432(+) AAAGTC/TAGTAG 1 -- ds500128Minor allele frequency- T:0.31NS EA NA WA CSA 2790
    rs77742041,2
    C,F,A,H--39302501(+) CTACAC/TAGGGG 1 -- ds500116Minor allele frequency- T:0.32NS EA NA WA CSA 930
    rs1446846701,2
    C--39302559(+) GTGTA-/TGTGTGT 1 -- ds50010--------
    rs93808481,2
    C,F,A,H--39302614(+) GCTTCT/CAGAAT 1 -- ds500121Minor allele frequency- C:0.27NA NS EA WA CSA 2482
    rs77542251,2
    C,F,A,H--39302723(+) TGTCCT/CGATGG 1 -- ds500125Minor allele frequency- C:0.36NS EA NA WA CSA 2477
    rs1931256551,2
    --39302725(+) TCCCGA/GTGGGA 1 -- ds50010--------
    rs1852646961,2
    --39302795(+) TGGCTC/TGTCTA 1 -- ds50010--------
    rs18877161,2
    C,F,O,A,H--39302832(-) GAGTCG/ACTGTT 1 -- ds500126Minor allele frequency- A:0.47NA EA MN NS WA CSA 2970

    HapMap Linkage Disequilibrium report for KIF6 (39297766 - 39547766 bp, first 250kb of KIF6)

    Structural Variations
         Database of Genomic Variants (DGV) 10/11 variations for KIF6 (see all 11):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2731955CNV Deletion23290073
    esv2521582CNV Insertion19546169
    esv271295CNV Insertion20981092
    nsv5271CNV Insertion18451855
    nsv885822CNV Loss21882294
    nsv830644CNV Loss17160897
    nsv885823CNV Loss21882294
    nsv508405CNV Loss20534489
    nsv830645CNV Loss17160897
    nsv462920CNV Loss19166990


    Human Gene Mutation Database (HGMD): KIF6
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613919    OMIM disorders: --

    7 diseases for KIF6:    About MalaCards
    coronary heart disease    ischemic heart disease    acute myocardial infarction    myocardial infarction
    prostate cancer    endotheliitis    prostatitis

    1 disease from the University of Copenhagen DISEASES database for KIF6:
    Myocardial infarction

    KIF6 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for KIF6 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    coronary heart disease 23.4 2 18222354 (2)

    Genetic Association Database (GAD): KIF6
    Human Genome Epidemiology (HuGE) Navigator: KIF6 (16 documents)

    Export disorders for KIF6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KIF6 gene, integrated from 9 sources (see all 48):
    (articles sorted by number of sources associating them with KIF6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A kinesin family member 6 variant is associated with coronary heart disease in the Women's Health Study. (PubMed id 18222354)1, 4, 9 Shiffman D....Ridker P.M. (2008)
    2. Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials. (PubMed id 18222353)1, 4, 9 Iakoubova O.A....Sacks F.M. (2008)
    3. Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: results from the PROVE IT-TIMI 22 study. (PubMed id 18222355)1, 4, 9 Iakoubova O.A....Braunwald E. (2008)
    4. Genetic variants in the KIF6 region and coronary even t reduction from statin therapy. (PubMed id 20886236)1, 4 Li Y....Iakoubova O.A. (2010)
    5. Investigation of KIF6 Trp719Arg in a case-control stu dy of myocardial infarction: a Costa Rican population. (PubMed id 20927332)1, 4 Bare L.A....Campos H. (2010)
    6. Lack of association between the Trp719Arg polymorphis m in kinesin-like protein-6 and coronary artery disease in 19 case-control stud ies. (PubMed id 20933357)1, 4 Assimes T.L....Quertermous T. (2010)
    7. Effect of pravastatin therapy on coronary events in c arriers of the KIF6 719Arg allele from the cholesterol and recurrent events tri al. (PubMed id 20403483)1, 4 Shiffman D....Sacks F.M. (2010)
    8. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    9. KIF6 Trp719Arg polymorphism and the effect of statin therapy in elderly patients: results from the PROSPER study. (PubMed id 20215968)1, 4 Iakoubova O.A....Shepherd J. (2010)
    10. Gene variants associated with ischemic stroke: the cardiovascular health study. (PubMed id 19023099)1, 4 Luke M.M....Psaty B.M. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 221458 HGNC: 21202 AceView: C6orf102 Ensembl:ENSG00000164627 euGenes: HUgn221458
    ECgene: KIF6 H-InvDB: KIF6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KIF6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KIF6 gene:
    Search GeneIP for patents involving KIF6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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