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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KIF4A Gene

protein-coding   GIFtS: 57
GCID: GC0XP069509

kinesin family member 4A
 Explore 4 diseases affiliated with
KIF4A via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for KIF4A    

Aliases
for KIF4A gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Kinesin Family Member 4A1 2     HSA2717841
KIF41 2 3 5     KIF4-G11
FLJ125301     KIF4G12
FLJ126551     Chromokinesin-A3
FLJ142041     Chromosome-Associated Kinesin KIF4A2
FLJ206311     Chromokinesin-A3

External Ids:    HGNC: 133391   Entrez Gene: 241372   Ensembl: ENSG000000908897   OMIM: 3005215   UniProtKB: O952393   

Export aliases for KIF4A gene to outside databases

Previous GC identifers: GC0XP065687 GC0XP066987 GC0XP067743 GC0XP068376 GC0XP069292 GC0XP069427 GC0XP069428 GC0XP063330


Summaries
for KIF4A gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for KIF4A:
This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP
dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles.
This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity
during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A
pseudogene of this gene is found on chromosome X.(provided by RefSeq, Mar 2010)

UniProtKB/Swiss-Prot: KIF4A_HUMAN, O95239
Function: Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the
metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and
midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle
stabilization

Gene Wiki entry for KIF4A


Genomic Views
for KIF4A gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_011669.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KIF4A gene promoter:
         AP-2alpha isoform 3   AP-2alpha isoform 2   Tal-1beta   E47   Egr-2   Hand1   AP-2alpha isoform 4   AP-2alpha   ITF-2   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: KIF4A promoter sequence
   Search SABiosciences Chromatin IP Primers for KIF4A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIF4A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq13.1   Ensembl cytogenetic band:  Xq13.1   HGNC cytogenetic band: Xq13.1

KIF4A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIF4A gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP069509:  view genomic region     (about GC identifiers)

Start:
 69,509,879 bp from pter      End:
 69,640,774 bp from pter
Size:
 130,896 bases      Orientation:
 plus strand

Proteins
for KIF4A gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: KIF4A_HUMAN, O95239 (See protein sequence)
Recommended Name: Chromosome-associated kinesin KIF4A  
Size: 1232 amino acids; 139881 Da
Subunit: Interacts with unphosphorylated PRC1 during late mitosis
Subcellular location: Nucleus matrix. Cytoplasm, cytoskeleton, spindle. Midbody. Chromosome. Note=Not present in the
nucleolus. In early mitosis, associated with the mitotic spindle, in anaphase, localized to the spindle midzone and,
in telophase and cytokinesis, to the midbody. In late cytokinesis, found in the center of the midbody. Associated with
chromosomes at all stages of mitosis
Sequence caution: Sequence=AAH49218.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A
sequence;
Secondary accessions: B2R7V5 D3DVU4 Q86TN3 Q86XX7 Q9NNY6 Q9NY24 Q9UMW3
Alternative splicing: 2 isoforms:  O95239-1   O95239-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KIF4A: NX_O95239

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O95239

    • KIF4A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_036442.3  
    ENSEMBL proteins: 
     ENSP00000363524   ENSP00000363509  
    Reactome Protein details: O95239
    Human Recombinant Protein Products: 
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    Uscn Proteins for KIF4A

    Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005694chromosome IEA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm TAS7929562
    GO:0005829cytosol TAS--


    KIF4A for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for KIF4A

    Protein Domains /
    Families
    for KIF4A gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    KIF4A for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR001752 Kinesin_motor_dom
     IPR019821 Kinesin_motor_CS

    Graphical View of Domain Structure for InterPro Entry O95239

    ProtoNet protein and cluster: O95239

    1 Blocks protein family: IPB001752 Kinesin

    UniProtKB/Swiss-Prot: KIF4A_HUMAN, O95239
    Similarity: Belongs to the kinesin-like protein family. Chromokinesin subfamily
    Similarity: Contains 1 kinesin-motor domain


    Function
    for KIF4A gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: KIF4A_HUMAN, O95239
    Function: Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the
    metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and
    midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle
    stabilization

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: KIF4A 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003777microtubule motor activity IEA--
    GO:0005524ATP binding IEA--


    KIF4A for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for KIF4A:
     G2 arrest  Increased G2M DNA content 

    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Kif4):
     normal 

    KIF4A for phenotypes           About GeneDecksing


    Pathways & Interactions
    for KIF4A gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Axon guidance
    		Axon guidance1.00
    		L1CAM interactions0.39
    		Developmental Biology0.69
    		Recycling pathway of L10.15
    2Immune System
    		Immune System1.00
    		Adaptive Immune System0.59
    3Kinesins
    		Kinesins1.00
    		Kinesins move along microtubules consuming ATP0.95
    4MHC class II antigen presentation
    		MHC class II antigen presentation1.00
    		Transport of antigen loaded MHC II molecules to surface0.59
    5Factors involved in megakaryocyte development and platelet production
    		Factors involved in megakaryocyte development and platelet production1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/12        Reactome Pathways for KIF4A (see all 12)
        Hemostasis
    L1CAM interactions
    Developmental Biology
    Adaptive Immune System
    Transport of antigen loaded MHC II molecules to surface



    KIF4A for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KIF4A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/778 Interacting proteins for KIF4A (O952392, 3 ENSP000003635244) via UniProtKB, MINT, STRING, and/or I2D (see all 778)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TBL1XR1Q9BZK72, ENSP000004055744MINT-7945693 MINT-7947479 STRING: ENSP00000405574
    TUBG1P232582, ENSP000002514134MINT-7945693 MINT-7947479 STRING: ENSP00000251413
    TUBGCP3Q96CW52, ENSP000002619654MINT-7945693 MINT-7947479 STRING: ENSP00000261965
    SUMO1P631652, 3, ENSP000003760764MINT-7947479 I2D: score=1 STRING: ENSP00000376076
    CDC5LQ994592, ENSP000003605324MINT-7945693 MINT-7947479 STRING: ENSP00000360532
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006996organelle organization TAS7929562
    GO:0007018microtubule-based movement TAS--
    GO:0007411axon guidance TAS--
    GO:0007596blood coagulation TAS--
    GO:0008089anterograde axon cargo transport TAS7929562


    KIF4A for ontologies           About GeneDecksing



    Drugs & Compounds
    for KIF4A gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KIF4A
    Search CenterWatch for drugs/clinical trials and news about KIF4A 

    Transcripts
    for KIF4A gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for KIF4A gene: 
    NM_012310.4  

    Unigene Cluster for KIF4A:

    Kinesin family member 4A
    Hs.648326  [show with all ESTs]
    Unigene Representative Sequence: NM_012310
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374403(uc004dyg.3 uc010nkw.3) ENST00000485406 ENST00000374388(uc004dyf.2)


    miRNA
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    hsa-miR-767-3p hsa-miR-516b hsa-miR-3143 hsa-miR-543
    SwitchGear 3'UTR luciferase reporter plasmid: KIF4A 3' UTR sequence
    Inhib. RNA
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AB208797.1 AF071592.2 AF179308.1 AF277375.1 AJ271784.1 AK000638.1 AK022592.1 AK022717.1 
    AK024266.1 BC003664.2 BC011801.1 BC038459.1 BC049218.1 BC050548.1 

    14 DOTS entries:

    DT.452160  DT.100779925  DT.101983228  DT.100811858  DT.100811859  DT.101984511  DT.120852914  DT.121288381 
    DT.75158650  DT.95237489  DT.95302581  DT.95369020  DT.100779924  DT.99928543 

    24/181 AceView cDNA sequences (see all 181):

    BM462717 AL571779 BQ055969 Z39592 AI492247 BE207964 AI611057 AA603659 
    BQ055679 BF037022 CA415618 CK000149 BM464206 BQ232841 BM802668 BF969754 
    F02874 AA679595 AA001833 BC011801 AL135268 BC003664 BE501179 CB132117 

    GeneLoc Exon Structure


    Expression
    for KIF4A gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KIF4A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTGTTGAAGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    KIF4A expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    HeartMyocardiumCardiac FibroblastsEpicardium
    OvaryAntral FollicleSecondary OocyteFemale Gametocytes, Germ Cells
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Adult human kidney epithelial cells (Primary Cell)Kidney

    See KIF4A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KIF4A

    SOURCE GeneReport for Unigene cluster: Hs.648326

    UniProtKB/Swiss-Prot: KIF4A_HUMAN, O95239
    Tissue specificity: Highly expressed in hematopoietic tissues, fetal liver, spleen, thymus and adult thymus and bone
    marrow. Lower levels are found in heart, testis, kidney, colon and lung

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    In Situ
    Assay Products:     
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    Orthologs
    for KIF4A gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for KIF4A gene from 8/25 species (see all 25)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves KIF4A1 kinesin family member 4A 72.96(n)
    76.66(a)    		   395823  NM_204975.1  NP_990306.1 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    (see all 3)    		 --
    		 7(a)
    67(a)
    (see all 3)    		 possible ortholog
    many ↔ many
    (see all 3)    		 5(98775181-98827158)
    GL343400.1(368365-390625)
    African clawed frog
    (Xenopus laevis)    		 Amphibia kif4a-A-prov2 kinesin family member 4A 75.36(n)    X82012.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc661252 hypothetical protein MGC66125 74.19(n)   393796  BC060673.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Kif19A3
    Klp3A1    		 microtubule-based movement kinesin motor3
    Kinesin-like protein at 3A1    		 38(a)
    (best of 3)3
    46.8(n)1
    38.26(a)1    		   88A93
    312401  NM_080314.21  NP_525053.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea klp-191 , 3 Kinesin motor domain3
    Protein KLP-191    		 32(a)
    (best of 2)3
    45.63(n)1
    34.78(a)1    		   III(13374305-13378476)3
    1767501  NM_067341.21  NP_499742.11 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons FRA11 kinesin family member 4/7/21/27 47.95(n)
    41.71(a)    		   834833  NM_124156.4  NP_199593.2 
    rice
    (Oryza sativa)    		 Liliopsida Os09g01145001 hypothetical protein 50.66(n)
    44.18(a)    		   4346402  NM_001069115.1  NP_001062580.1 


    ENSEMBL Gene Tree for KIF4A (if available)
    TreeFam Gene Tree for KIF4A (if available) 

    Paralogs
    for KIF4A gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KIF4A gene
    KIF5C2  KIF21A2  KIF112  KIF3B2  KIF21B2  KIF92  KIF172  KIF4B2  
    KIF272  KIF3A2  KIF5B2  KIF62  KIF152  CENPE2  KIF5A2  KIF72  
    KIF3C2  
    8 SIMAP similar genes for KIF4A using alignment to 2 protein entries:     KIF4A_HUMAN (see all proteins):
    KIF4B    CENPE    KIF21A    KIF17    KIF3A    KIF21B
    KIF3B    KIF16B

    KIF4A for paralogs           About GeneDecksing



    Genomic Variants
    for KIF4A gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1394 NCBI SNPs in KIF4A are shown (see all 1394)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr X posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1504733011,2
    		C,--69507937(+) AGTAAC/TGATCC 2 -- us2k1 int10--------
    rs1454188171,2
    		C,--69508065(+) GACCAC/TAAACA 2 -- int1 us2k10--------
    rs1906135561,2
    		--69508103(+) AATAGC/TTCAGC 2 -- us2k1 int10--------
    rs1828578371,2
    		--69508220(+) CCCCCA/CAACAC 2 -- us2k1 int10--------
    rs348319141,2
    		C--69508373(+) AAGACA/CCAGCA 2 -- int1 us2k10--------
    rs1879567691,2
    		--69508498(+) ACACAA/GACTAA 2 -- us2k1 int10--------
    rs1491788701,2
    		C,--69508506(+) TAAATA/GAGTAG 2 -- us2k1 int10--------
    rs1919249361,2
    		--69508643(+) TCTGCC/TTCCCA 2 -- us2k1 int10--------
    rs12078601,2
    		C,--69508744(-) AAACCC/GCGTCT 2 -- us2k1 int18Minor allele frequency- G:0.00NA EA WA CSA 259
    rs1829896231,2
    		--69508877(+) GAAGGC/TTCCAA 2 -- int1 us2k10--------

    HapMap Linkage Disequilibrium report for KIF4A (69509879 - 69640774 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for KIF4A
         1 CNV: 7797
    Locus Specific Mutation Databases (LSDB): KIF4A

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for KIF4A gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    KIF4A for disorders           About GeneDecksing

    OMIM gene information: 300521    OMIM disorders: --

    4 diseases for KIF4A:    About MalaCards
    retinoblastoma    lung cancer    immunodeficiency    carcinoma

    2 Novoseek disease relationships for KIF4A gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoblastoma 29 3 9168136 (3)
    tumors 0 2 11745462 (1)


    Export disorders for KIF4A gene to outside databases

    Publications
    for KIF4A gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KIF4A gene, integrated from 9 sources (see all 67):
    (articles sorted by number of sources associating them with KIF4A)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesis. (PubMed id 15625105)1, 2, 9 Zhu C. and Jiang W. (2005)
    2. Human kinesin superfamily member 4 is dominantly localized in the nuclear matrix and is associated with chromosomes during mitosis. (PubMed id 11736643)1, 2, 9 Lee Y.M.... Kim W. (2001)
    3. Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation. (PubMed id 15297875)1, 2, 9 Kurasawa Y.... Todokoro K. (2004)
    4. Increased chromokinesin immunoreactivity in retinoblastoma cells. (PubMed id 9168136)1, 2, 9 Yan R.-T. and Wang S.-Z. (1997)
    5. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    7. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    10. Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization. (PubMed id 10773663)1, 3 Ha M.J....Kim W. (2000)

    External Searches for KIF4A gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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    Genome Databases showing KIF4A gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 24137 HGNC: 13339 AceView: KIF4A Ensembl:ENSG00000090889 euGenes: HUgn24137
    ECgene: KIF4A H-InvDB: KIF4A

    Other Databases showing KIF4A gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing KIF4A gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KIF4A Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for KIF4A gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for KIF4A gene:
    Search GeneIP for patents involving KIF4A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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