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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KIF26A Gene

protein-coding   GIFtS: 50
GCID: GC14P104605

kinesin family member 26A

 Explore 2 diseases affiliated with
KIF26A via our new
 Human Malady Compendium 
Biological research products
for KIF26A
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Kinesin Family Member 26A1 2
KIAA12361 3 5
DKFZP434N1781
KIF26A Variant Protein2
Kinesin-Like Protein KIF26A2

External Ids:    HGNC: 202261   Entrez Gene: 261532   Ensembl: ENSG000000667357   OMIM: 6132315   UniProtKB: Q9ULI43   

Export aliases for KIF26A gene to outside databases

Previous GC identifers: GC14P098420 GC14P102595 GC14P103674 GC14P084784


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: KI26A_HUMAN, Q9ULI4
Function: Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth
signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents
GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based
motility due to the absence of ATPase activity (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KIF26A gene promoter:
         USF1   Pbx1a   Lmo2   Arnt   Egr-4   Max   CP2   USF-1   Hand1   c-Myc   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for KIF26A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIF26A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.33   Ensembl cytogenetic band:  14q32.33   HGNC cytogenetic band: 14q32.33

KIF26A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIF26A gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P104605:  view genomic region     (about GC identifiers)

Start:
104,605,060 bp from pter      End:
104,647,235 bp from pter
Size:
42,176 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: KI26A_HUMAN, Q9ULI4 (See protein sequence)
Recommended Name: Kinesin-like protein KIF26A  
Size: 1882 amino acids; 194590 Da
Subunit: Interacts with GRB2 (via SH2 domain) (By similarity)
Subcellular location: Cytoplasm, cytoskeleton (Probable)
Caution: In contrast to other kinesin-like proteins, residues required for ATPase activity are missing
Sequence caution: Sequence=AAH09415.1; Type=Erroneous initiation;
Secondary accessions: Q8TAZ7 Q96GK3 Q9UFL3

Explore the universe of human proteins at neXtProt for KIF26A: NX_Q9ULI4

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9ULI4

  • KIF26A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_056471.1  
    ENSEMBL proteins: 
     ENSP00000388241   ENSP00000325452  
    Reactome Protein details: Q9ULI4
    Human Recombinant Protein Products: 
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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for KIF26A

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005874microtubule IEA--
    GO:0005875microtubule associated complex IEA--


    KIF26A for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    KIF26A for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001752 Kinesin_motor_dom

    Graphical View of Domain Structure for InterPro Entry Q9ULI4

    ProtoNet protein and cluster: Q9ULI4

    1 Blocks protein family: IPB001752 Kinesin

    UniProtKB/Swiss-Prot: KI26A_HUMAN, Q9ULI4
    Similarity: Belongs to the kinesin-like protein family. KIF26 subfamily
    Similarity: Contains 1 kinesin-motor domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: KI26A_HUMAN, Q9ULI4
    Function: Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth
    signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents
    GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based
    motility due to the absence of ATPase activity (By similarity)

    miRNA
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    hsa-miR-320a hsa-miR-520d-5p hsa-miR-1271 hsa-miR-29c hsa-miR-29a hsa-let-7a-2* hsa-miR-3921 hsa-miR-511
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    Inhib. RNA
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003777NOT microtubule motor activity ISS--
    GO:0005515protein binding ----
    GO:0005524ATP binding IEA--
    GO:0008017microtubule binding ISS--
    GO:0016887NOT ATPase activity ISS--


    KIF26A for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for KIF26A:
     Increased HPV18 LCR reporter a 

    Animal Models:
         Mouse knock-out Kif26atm1.1Noh for KIF26A
         7 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Kif26a):
     cellular  digestive/alimentary  growth/size  homeostasis/metabolism  mortality/aging 
     nervous system  no phenotypic analysis 

    KIF26A for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Immune System
    Immune System1.00
    Adaptive Immune System0.59
    2Kinesins
    Kinesins1.00
    Kinesins move along microtubules consuming ATP0.95
    3MHC class II antigen presentation
    MHC class II antigen presentation1.00
    Transport of antigen loaded MHC II molecules to surface0.59
    4Factors involved in megakaryocyte development and platelet production
    Factors involved in megakaryocyte development and platelet production1.00
    5Platelet activation, signaling and aggregation
    Hemostasis0.43

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/8        Reactome Pathways for KIF26A (see all 8)
        Hemostasis
    Adaptive Immune System
    Transport of antigen loaded MHC II molecules to surface
    Kinesins move along microtubules consuming ATP
    Factors involved in megakaryocyte development and platelet production



    KIF26A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIF26A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/44 Interacting proteins for KIF26A (Q9ULI43 ENSP000003882414) via UniProtKB, MINT, STRING, and/or I2D (see all 44)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK10P537793, ENSP000003521574I2D: score=3 STRING: ENSP00000352157
    GRB2P629933, ENSP000003390074I2D: score=2 STRING: ENSP00000339007
    MAP3K10Q027793I2D: score=2 
    MAP3K7O433183I2D: score=2 
    ARRB1P494073I2D: score=1 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001560regulation of cell growth by extracellular stimulus ISS--
    GO:0007018microtubule-based movement TAS--
    GO:0007596blood coagulation TAS--
    GO:0009968negative regulation of signal transduction ISS--
    GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II TAS--


    KIF26A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KIF26A
    Search CenterWatch for drugs/clinical trials and news about KIF26A / KI26A 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KIF26A gene: 
    NM_015656.1  

    Unigene Cluster for KIF26A:

    Kinesin family member 26A
    Hs.134970  [show with all ESTs]
    Unigene Representative Sequence: NM_015656
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000423312 ENST00000315264(uc001yos.4)

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    hsa-miR-320a hsa-miR-520d-5p hsa-miR-1271 hsa-miR-29c hsa-miR-29a hsa-let-7a-2* hsa-miR-3921 hsa-miR-511
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    Additional cDNA sequence: 

    AB033062.2 AB290161.1 AK026406.1 AL117589.1 BC009415.1 BC025353.1 

    2 DOTS entries:

    DT.40310256  DT.97839528 

    24/46 AceView cDNA sequences (see all 46):

    AI094289 AB033062 BX280272 CA397394 BM821339 AI866870 BC025353 AK026406 
    BM559278 BE545089 BQ942959 BM826443 BV168643 AW674509 BG473075 BI770102 
    BM850896 BG912662 BU538460 BM789579 BC009415 BV168640 AW675120 BV168641 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KIF26A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATGGTCACCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    KIF26A expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeInner Nuclear LayernGnG Amacrine CellsAmacrine, Retina
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    PureStem™ progenitor EN7 (Embryonic Progenitor Cell)
    Definitive endoderm-like cells (A scalable, suspensi...)

    See KIF26A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KIF26A

    SOURCE GeneReport for Unigene cluster: Hs.134970
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF26A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for KIF26A gene from 7/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kif26a1 , 5 kinesin family member 26A1, 5 79.02(n)1
    78.95(a)1
      12 (61.14 cM)5
    6683031  NM_001097621.11  NP_001091090.11 
     1121462355 
    chicken
    (Gallus gallus)
    Aves KIF26A1 kinesin family member 26A 59.94(n)
    61.15(a)
      423489  XM_421394.3  XP_421394.3 
    lizard
    (Anolis carolinensis)
    Reptilia KIF26A6
    --
    53(a)
    1 ↔ 1
    1(5372804-5418497)
    African clawed frog
    (Xenopus laevis)
    Amphibia CF547636.12   -- 77.33(n)    CF547636.1 
    zebrafish
    (Danio rerio)
    Actinopterygii kif26a1 kinesin family member 26A 57.22(n)
    55.45(a)
      561709  XM_685123.5  XP_690215.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG145356
    --
    23(a)
    possible ortholog
    2L(7844905-7855255)
    worm
    (Caenorhabditis elegans)
    Secernentea vab-86
    Kinesin-like protein vab-8
    20(a)
    possible ortholog
    V(12213308-12225901)


    ENSEMBL Gene Tree for KIF26A (if available)
    TreeFam Gene Tree for KIF26A (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KIF26A gene
    KIF26B2  
    1 SIMAP similar gene for KIF26A using alignment to 2 protein entries:     KI26A_HUMAN (see all proteins):
    KIF26B

    KIF26A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/955 NCBI SNPs in KIF26A are shown (see all 955    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1147101311,2
    F,--104603191(+) AGGGAT/CTCTCG 1 -- us2k11Minor allele frequency- C:0.15WA 118
    rs348390451,2
    C,F,--104603271(+) GAGGTA/GACTCC 1 -- us2k15Minor allele frequency- G:0.47NA EA 246
    rs740871491,2
    C,--104603532(+) GTCCTC/GAGTAC 1 -- us2k12Minor allele frequency- G:0.16WA 120
    rs1911573021,2
    --104603556(+) TGGGCA/TGACGC 1 -- us2k10--------
    rs740871511,2
    C,--104603586(+) TGCGAA/TGAGAC 1 -- us2k12Minor allele frequency- T:0.16WA 120
    rs71563951,2
    C,F,H,--104603873(+) GTATGC/TGCCGG 1 -- us2k124Minor allele frequency- T:0.19NS EA NA WA CSA 2352
    rs1840323111,2
    --104603886(+) GCCGCG/TTGTCC 1 -- us2k10--------
    rs1406094281,2
    --104604098(+) GCCGCC/GGATGC 1 -- us2k10--------
    rs125883931,2
    C,H,--104604135(+) ACAGAA/GCAACT 1 -- us2k14Minor allele frequency- G:0.44NA EA 244
    rs1439470361,2
    C,--104604154(+) AGGGC-/GCGGGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for KIF26A (104605060 - 104647235 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for KIF26A
         2 CNVs: 49289 29960
         2 Indels: 102029 61416

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIF26A
    DNA2.0 Custom Variant and Variant Library Synthesis for KIF26A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    KIF26A for disorders           About GeneDecksing

    OMIM gene information: 613231    OMIM disorders: --

    2 diseases for KIF26A:    About MalaCards
    megacolon    neuronitis

    1 disease from the University of Copenhagen DISEASES database for KIF26A:
    Megacolon

    Export disorders for KIF26A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KIF26A gene integrated from 9 sources:
    (articles sorted by number of sources associating them with KIF26A)
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    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2, 3 Nagase T.... Ohara O. (1999)
    2. All kinesin superfamily protein, KIF, genes in mouse and human. (PubMed id 11416179)1, 3 Miki H....Hirokawa N. (2001)
    3. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
    4. KIF26A is an unconventional kinesin and regulates GDNF-Ret signaling in enteric neuronal development. (PubMed id 19914172)1 Zhou R.... Hirokawa N. (2009)
    5. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. (PubMed id 17620599)1 Xiao K....Lefkowitz R.J. (2007)
    6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)2 Heilig R.... Weissenbach J. (2003)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)2 Nakajima D.... Nagase T. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26153 HGNC: 20226 AceView: KIF26A Ensembl:ENSG00000066735 euGenes: HUgn26153
    ECgene: KIF26A H-InvDB: KIF26A

    (According to HUGE)
    About This Section
    HUGE: KIAA1236

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KIF26A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KIF26A gene:
    Search GeneIP for patents involving KIF26A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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