Aliases for KIF23 Gene
External Ids for KIF23 Gene
Previous HGNC Symbols for KIF23 Gene
Previous GeneCards Identifiers for KIF23 Gene
The protein encoded by this gene is a member of kinesin-like protein family. This family includes microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein has been shown to cross-bridge antiparallel microtubules and drive microtubule movement in vitro. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for KIF23 Gene
KIF23 (Kinesin Family Member 23) is a Protein Coding gene. Diseases associated with KIF23 include Dyserythropoietic Anemia, Congenital, Type Iii and Congenital Dyserythropoietic Anemia. Among its related pathways are Cell Cycle, Mitotic and Response to elevated platelet cytosolic Ca2+. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF20B.
UniProtKB/Swiss-Prot for KIF23 Gene
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro.