Aliases for KIF22 Gene
External Ids for KIF22 Gene
Previous Symbols for KIF22 Gene
The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
GeneCards Summary for KIF22 Gene
KIF22 (Kinesin Family Member 22) is a Protein Coding gene. Diseases associated with KIF22 include spondyloepimetaphyseal dysplasia with joint laxity, type 2 and spondyloepimetaphyseal dysplasia with multiple dislocations. Among its related pathways are Class I MHC mediated antigen processing and presentation and Hemostasis. GO annotations related to this gene include microtubule binding and microtubule motor activity. An important paralog of this gene is KIF14.
UniProtKB/Swiss-Prot for KIF22 Gene
Kinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA