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KIF21B Gene

protein-coding   GIFtS: 51
GCID: GC01M200938

Kinesin Family Member 21B

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Kinesin Family Member 21B1 2
KIAA04493 5
Kinesin-Like Protein KIF21B2

External Ids:    HGNC: 294421   Entrez Gene: 230462   Ensembl: ENSG000001168527   OMIM: 6083225   UniProtKB: O750373   

Export aliases for KIF21B gene to outside databases

Previous GC identifers: GC01M198226 GC01M198231 GC01M197674 GC01M199205 GC01M172186


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for KIF21B Gene:
This gene encodes a member of the kinesin superfamily. Kinesins are ATP-dependent microtubule-based motor proteins
that are involved in the intracellular transport of membranous organelles. Single nucleotide polymorphisms in
this gene are associated with inflammatory bowel disease and multiple sclerosis. Alternatively spliced transcript
variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Nov 2011)

GeneCards Summary for KIF21B Gene:
KIF21B (kinesin family member 21B) is a protein-coding gene. Diseases associated with KIF21B include inflammatory bowel disease, and multiple sclerosis. GO annotations related to this gene include microtubule binding and microtubule motor activity. An important paralog of this gene is KIF4A.

UniProtKB/Swiss-Prot: KI21B_HUMAN, O75037
Function: Microtubule-binding motor protein probably involved in neuronal dendritic transport. In vitro, has a
plus-end directed motor activity (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the KIF21B gene promoter:
         RFX1   NF-YA   NF-YC   CBF-C   NF-YB   CBF-B   CBF-A   CP1A   CP1C   NF-Y   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKIF21B promoter sequence
   Search Chromatin IP Primers for KIF21B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KIF21B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.1   Ensembl cytogenetic band:  1q32.1   HGNC cytogenetic band: 1q32.1

KIF21B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIF21B gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M200938:  view genomic region     (about GC identifiers)

Start:
200,938,520 bp from pter      End:
200,992,828 bp from pter
Size:
54,309 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: KI21B_HUMAN, O75037 (See protein sequence)
Recommended Name: Kinesin-like protein KIF21B  
Size: 1637 amino acids; 182662 Da
Sequence caution: Sequence=BAA32294.2; Type=Erroneous initiation;
Secondary accessions: B2RP62 B7ZMI0 Q5T4J3
Alternative splicing: 4 isoforms:  O75037-1   O75037-2   O75037-3   O75037-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KIF21B: NX_O75037

Explore proteomics data for KIF21B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KIF21B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001239029.1  NP_001239031.1  NP_001239032.1  NP_060066.2  

    ENSEMBL proteins: 
     ENSP00000328494   ENSP00000433808   ENSP00000353724   ENSP00000411831  

    KIF21B Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for KIF21B

    KIF21B Antibody Products:

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    Cloud-Clone Corp. ELISAs for KIF21B
    Cloud-Clone Corp. CLIAs for KIF21B


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    KIF: Kinesins
    WDR: WD repeat domain containing

    Selected InterPro protein domains (see all 9):
     IPR009053 Prefoldin
     IPR019775 WD40_repeat_CS
     IPR027417 P-loop_NTPase
     IPR001680 WD40_repeat
     IPR001752 Kinesin_motor_dom

    Graphical View of Domain Structure for InterPro Entry O75037

    ProtoNet protein and cluster: O75037

    UniProtKB/Swiss-Prot: KI21B_HUMAN, O75037
    Similarity: Belongs to the kinesin-like protein family
    Similarity: Contains 1 kinesin-motor domain
    Similarity: Contains 7 WD repeats


    KIF21B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KI21B_HUMAN, O75037
    Function: Microtubule-binding motor protein probably involved in neuronal dendritic transport. In vitro, has a
    plus-end directed motor activity (By similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003777microtubule motor activity IEA--
    GO:0005515protein binding ----
    GO:0005524ATP binding IEA--
    GO:0008017microtubule binding IEA--
         
    KIF21B for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for KIF21B:
     Cell division defect  Increased G2M DNA content  Upregulation of Wnt/beta-caten 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Kif21b):
     cellular 

    KIF21B for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KIF21B
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KIF21B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for KIF21B

    miRNA
    Products:
        
    miRTarBase miRNAs that target KIF21B:
    hsa-mir-26b-5p (MIRT029731)

    Block miRNA regulation of human, mouse, rat KIF21B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KIF21B (see all 75):
    hsa-miR-485-3p hsa-miR-938 hsa-miR-30d hsa-miR-3653 hsa-miR-30a hsa-miR-3613-3p hsa-miR-508-5p hsa-miR-2113
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for KIF21B
    Predesigned siRNA for gene silencing in human, mouse, rat KIF21B

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for KIF21B (see all 7)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KIF21B (NM_017596)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KIF21B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIF21B

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF21B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KI21B_HUMAN, O75037: Cytoplasm, cytoskeleton (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton3
    cytosol3

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005871kinesin complex IEA--
    GO:0005874microtubule IEA--

    KIF21B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KIF21B
    Interactions:

        Search GeneGlobe Interaction Network for KIF21B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    Selected Interacting proteins for KIF21B (O750372, 3 ENSP000003284944) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TK1P041832, 3MINT-8273631 I2D: score=2 
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    YWHAEP622583I2D: score=1 
    GCSAMENSP000003094874STRING: ENSP00000309487
    ENSG00000225553ENSP000003919014STRING: ENSP00000391901
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007018microtubule-based movement IEA--

    KIF21B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KIF21B (KI21B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for KIF21B gene (4 alternative transcripts): 
    NM_001252100.1  NM_001252102.1  NM_001252103.1  NM_017596.3  

    Unigene Cluster for KIF21B:

    Kinesin family member 21B
    Hs.169182  [show with all ESTs]
    Unigene Representative Sequence: NM_001252100
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000332129(uc001gvs.2 uc009wzl.2 uc001gvr.2 uc010ppn.2)
    ENST00000461742 ENST00000360529 ENST00000422435 ENST00000534043(uc001gvt.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KIF21B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KIF21B (see all 75):
    hsa-miR-485-3p hsa-miR-938 hsa-miR-30d hsa-miR-3653 hsa-miR-30a hsa-miR-3613-3p hsa-miR-508-5p hsa-miR-2113
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KIF21B
    Predesigned siRNA for gene silencing in human, mouse, rat KIF21B
    Clone
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    OriGene clones in human, mouse for KIF21B (see all 7)
    OriGene ORF clones in mouse, rat for KIF21B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KIF21B (NM_017596)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KIF21B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIF21B
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for KIF21B
    OriGene qSTAR qPCR primer pairs in human, mouse for KIF21B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KIF21B
      QuantiTect SYBR Green Assays in human, mouse, rat KIF21B
      QuantiFast Probe-based Assays in human, mouse, rat KIF21B

    Additional mRNA sequence: 

    AB007918.2 AL137395.1 AM177180.1 BC031927.1 BC052964.1 BC078676.1 BC137281.1 BC144557.1 

    6 DOTS entries:

    DT.85105249  DT.95129471  DT.40115568  DT.100822040  DT.95167364  DT.102828181 

    Selected AceView cDNA sequences (see all 121):

    BF934208 BC052964 BC078676 AJ705143 BU735773 BX645784 BM703057 AW468259 
    BM850865 BC031927 CK299723 BM697589 T33465 CR596112 AI832692 BU169353 
    CR608417 T33421 BM825198 AA911750 BM728300 BX418067 BG820466 BM929801 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KIF21B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGTACATTT
    KIF21B Expression
    About this image


    KIF21B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    KIF21B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KIF21B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.169182
        Custom PCR Arrays for KIF21B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF21B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for KIF21B gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kif21b1 , 5 kinesin family member 21B1, 5 88.58(n)1
    95.86(a)1
      1 (59.61 cM)5
    165651  NM_001039472.11  NP_001034561.11 
     1361313895 
    chicken
    (Gallus gallus)
    Aves KIF21B1 kinesin family member 21B 83(n)
    89.86(a)
      421178  XM_004934815.1  XP_004934872.1 
    lizard
    (Anolis carolinensis)
    Reptilia KIF21B6
    kinesin family member 21B
    82(a)
    1 ↔ 1
    4(124567118-124643524)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia kif21b1 kinesin family member 21B 64.81(n)
    70.91(a)
      779607  XM_004910720.1  XP_004910777.1 
    zebrafish
    (Danio rerio)
    Actinopterygii kif21b1 kinesin family member 21B 73.69(n)
    77.69(a)
      570502  XM_693989.6  XP_699081.6 
    fruit fly
    (Drosophila melanogaster)
    Insecta Klp31E6
    Klp31E
    44(a)
    1 → many
    2L(10414017-10418991)
    worm
    (Caenorhabditis elegans)
    Secernentea klp-126
    Protein KLP-12, isoform a (klp-12) mRNA, complete ...
    36(a)
    1 → many
    IV(11341325-11359863) WBGene00002223
    rice
    (Oryza sativa)
    Liliopsida Os.226302 Oryza sativa (japonica cultivar-group) isolate 29946 more 77.38(n)    AK100974.1 


    ENSEMBL Gene Tree for KIF21B (if available)
    TreeFam Gene Tree for KIF21B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KIF21B gene
    KIF4A2  KIF3A2  KIF5B2  KIF5C2  KIF21A2  KIF112  KIF3B2  KIF172  
    CENPE2  KIF152  KIF5A2  KIF72  KIF4B2  KIF272  KIF3C2  
    8 SIMAP similar genes for KIF21B using alignment to 2 protein entries:     KI21B_HUMAN (see all proteins):
    KIF21A    DKFZp779C159    KIF5B    KIF3A    KIF5C    KIF6
    KIF5A    KIF4A

    KIF21B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KIF21B (see all 1239)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs104948291,2
    C,F,A,H--200938029(-) TAACAC/TGTACC 4 -- ds5001107Minor allele frequency- T:0.28NS NA EA PA EU CA WA CSA 6853
    rs1147291121,2
    C,F--200938134(+) CATCCC/TGAGAC 4 -- ds50011Minor allele frequency- T:0.06WA 118
    rs1485594651,2
    --200938294(+) AACATA/GTGGAG 4 -- ds50010--------
    rs1857594801,2
    --200938312(+) GAGAAC/TGTGAC 4 -- ds50010--------
    rs49152101,2
    C--200938474(+) CAAAAG/TTCAGC 4 -- ds50015Minor allele frequency- T:0.21NA WA EA 362
    rs1909582031,2
    C--200938790(+) TCCTCA/C/GGCTCT 8 -- ut310--------
    rs1429907381,2
    --200939131(+) CGGGAA/CACACA 4 -- ut310--------
    rs1834052451,2
    --200939312(+) CTAACA/GTCACT 4 -- ut310--------
    rs1426043711,2
    --200939337(+) GTGTCA/TCCCTC 4 -- ut310--------
    rs1142070361,2
    C,F--200939371(+) GTCCCC/TGCAAC 4 -- ut311Minor allele frequency- T:0.03WA 118

    HapMap Linkage Disequilibrium report for KIF21B (200938520 - 200992828 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for KIF21B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv989611CNV Deletion20482838
    esv2678555CNV Deletion23128226
    esv2721395CNV Deletion23290073
    esv33174CNV Loss17666407

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KIF21B
    DNA2.0 Custom Variant and Variant Library Synthesis for KIF21B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608322    OMIM disorders: --

    12 diseases for KIF21B:    
    About MalaCards
    inflammatory bowel disease    multiple sclerosis    ankylosing spondylitis    spondylitis
    ulcerative colitis    crohn's disease    tonsillitis    thyroiditis
    cerebritis    malaria    neuronitis    prostatitis


    KIF21B for disorders           About GeneDecksing

    Genetic Association Database (GAD): KIF21B
    Human Genome Epidemiology (HuGE) Navigator: KIF21B (5 documents)

    Export disorders for KIF21B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KIF21B gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with KIF21B)
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    1. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. (PubMed id 9455484)1, 2, 3 Seki N.... Ohara O. (DNA Res. 1997)
    2. Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. (PubMed id 21743469)1, 4 Evans D.M.... . (Nat. Genet. 2011)
    3. Replication of KIF21B as a susceptibility locus for multiple sclerosis. (PubMed id 20587413)1, 4 Goris A....Dubois B. (J. Med. Genet. 2010)
    4. Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. (PubMed id 19915572)1, 4  ....Strachan D.P. (Nat. Genet. 2009)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    6. Association of common variants in KIF21B and ankylosing spondylitis in a Chinese Han population: a replication study. (PubMed id 24065353)1 Liu Y....Liu Q. (Immunogenetics 2013)
    7. TRIM3 regulates the motility of the kinesin motor protein KIF21B. (PubMed id 24086586)1 LabontAc D....Kneussel M. (PLoS ONE 2013)
    8. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. (PubMed id 23453885)1 (Lancet 2013)
    9. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. (PubMed id 23128233)1 Jostins L....Cho J.H. (Nature 2012)
    10. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 JAoger S....Krogan N.J. (Nature 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23046 HGNC: 29442 AceView: KIF21B Ensembl:ENSG00000116852 euGenes: HUgn23046
    ECgene: KIF21B H-InvDB: KIF21B

    (According to HUGE)
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    HUGE: KIAA0449

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KIF21B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KIF21B gene:
    Search GeneIP for patents involving KIF21B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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