External Ids for KIF21B Gene
Previous GeneCards Identifiers for KIF21B Gene
This gene encodes a member of the kinesin superfamily. Kinesins are ATP-dependent microtubule-based motor proteins that are involved in the intracellular transport of membranous organelles. Single nucleotide polymorphisms in this gene are associated with inflammatory bowel disease and multiple sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
GeneCards Summary for KIF21B Gene
KIF21B (Kinesin Family Member 21B) is a Protein Coding gene. Diseases associated with KIF21B include Orchitis and Congenital Fibrosis Of The Extraocular Muscles. Among its related pathways are Platelet activation, signaling and aggregation and Vesicle-mediated transport. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF21A.
UniProtKB/Swiss-Prot for KIF21B Gene
Microtubule-binding motor protein probably involved in neuronal dendritic transport. In vitro, has a plus-end directed motor activity (By similarity).