KIF21A Gene
protein-coding GIFtS: 57
GCID: GC12M039687
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kinesin family member 21A(Previous names: fibrosis of the extraocular muscles, congenital, 1 )
(Previous symbol: FEOM1)
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Aliases
for KIF21A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Kinesin Family Member 21A1 2 | | FLJ200521 | | FEOM11 2 5 | | Fibrosis Of The Extraocular Muscles, Congenital, 11 | | Kinesin-Like Protein KIF22 3 | | FEOM3A2 | | Renal Carcinoma Antigen NY-REN-622 3 | | Kinesin-Like Protein KIF21A2 | | CFEOM12 5 | | KIF23 | | KIAA17083 5 | | CFEOM3B5 |
Export aliases for KIF21A gene to outside databasesPrevious GC identifers: GC12U990160 GC12M039586 GC12M039404 GC12M037973 GC12M036712 |
Summaries
for KIF21A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for KIF21A:
This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterizedby an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may beinvolved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis ofextraocular muscles-1. Alternate splicing results in multiple transcript variants.(provided by RefSeq, Mar 2010)
UniProtKB/Swiss-Prot: KI21A_HUMAN, Q7Z4S6Function: Microtubule-binding motor protein probably involved in neuronal axonal transport. In vitro, has a plus-enddirected motor activity (By similarity)
Gene Wiki entry for KIF21A
|
Genomic Views
for KIF21A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIF21A gene promoter:
HFH-3 C/EBPalpha YY1 FOXI1 S8 POU2F1 HFH-1 POU2F1a TGIF
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIF21A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIF21A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q12 Ensembl cytogenetic band: 12q12 HGNC cytogenetic band: 12q12KIF21A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M039687: view genomic region
(about GC identifiers)
Start:
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39,687,030 bp from pter |
End:
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39,837,192 bp from pter |
Size:
|
150,163 bases |
Orientation:
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minus strand |
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Proteins
for KIF21A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: KI21A_HUMAN, Q7Z4S6 (See
protein sequence)Recommended Name: Kinesin-like protein KIF21A Size: 1674 amino acids; 187179 Da
Subcellular location: Cytoplasm, cytoskeleton (Probable)
Sequence caution: Sequence=AAD42883.1; Type=Frameshift; Positions=185, 191, 380, 405; Sequence=AAH41430.1;Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence; Sequence=AAP97680.1;Type=Frameshift; Positions=185, 191; Sequence=BAA90916.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence.Potential poly-A sequence;
Secondary accessions: A8MX28 B0I1R9 Q6UKL9 Q7Z668 Q86WZ5 Q8IVZ8 Q9C0F5 Q9NXU4 Q9Y590Alternative splicing: 4 isoforms: Q7Z4S6-1 Q7Z4S6-2 Q7Z4S6-3 Q7Z4S6-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for KIF21A: NX_Q7Z4S6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7Z4S6
KIF21A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001166934.1 NP_001166935.1 NP_001166936.1 NP_060111.2
ENSEMBL proteins: ENSP00000354851 ENSP00000448792 ENSP00000447765 ENSP00000445606 ENSP00000354878 ENSP00000438075 ENSP00000449698 ENSP00000447070 ENSP00000449700 ENSP00000379029
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
KIF21A for ontologies About GeneDecksing
KIF21A Antibody Products:
Assay Products for KIF21A: |
Protein
Domains /
Families
for KIF21A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
KIF21A for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q7Z4S6ProtoNet protein and cluster: Q7Z4S6 1 Blocks protein family: IPB001752 Kinesin
UniProtKB/Swiss-Prot: KI21A_HUMAN, Q7Z4S6Similarity: Belongs to the kinesin-like protein familySimilarity: Contains 1 kinesin-motor domainSimilarity: Contains 7 WD repeats |
Function
for KIF21A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: KI21A_HUMAN, Q7Z4S6Function: Microtubule-binding motor protein probably involved in neuronal axonal transport. In vitro, has a plus-enddirected motor activity (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIF21A (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIF21A (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): KIF21A (NM_017641) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIF21A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIF21A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF21A |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
KIF21A for ontologies About GeneDecksing
|
Pathways & Interactions
for KIF21A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Reelin Pathway (Cajal-Retzius cells) | |
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for KIF21A
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIF21A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/743 Interacting proteins for KIF21A (Q7Z4S61, 2, 3 ENSP000003548514) via UniProtKB, MINT, STRING, and/or I2D (see all 743)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007018 | microtubule-based movement |
IEA | -- |
KIF21A for ontologies About GeneDecksing
|
Drugs & Compounds
for KIF21A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KIF21A
Search CenterWatch for drugs/clinical trials and news about KIF21A / KI21A
|
Transcripts
for KIF21A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KIF21A gene (4 alternative transcripts): NM_001173463.1 NM_001173464.1 NM_001173465.1 NM_017641.3 Unigene Cluster for KIF21A: Kinesin family member 21A Hs.374201 [show with all ESTs]Unigene Representative Sequence: NM_00117346415 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000547733(uc001rlt.3) ENST00000361961(uc001rlu.3 uc001rlv.3 uc001rlw.3 uc001rlx.3 uc001rlz.3 uc010skl.2)
ENST00000551264 ENST00000552961 ENST00000544797 ENST00000361418 ENST00000541463
ENST00000547745 ENST00000547108 ENST00000552475 ENST00000551066 ENST00000546817
ENST00000550429 ENST00000552908 ENST00000395670(uc001rly.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIF21A (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIF21A (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): KIF21A (NM_017641) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIF21A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIF21A |
Additional cDNA sequence: AB051495.2 AB290166.1 AF155117.1 AF450487.1 AK000059.1 AM177179.1 AY368076.1 BC032344.1 BC041430.1 BC047572.1 BC136414.1 BX537855.1 8 DOTS entries: DT.313386 DT.100680848 DT.99956111 DT.100782971 DT.99978500 DT.95262865 DT.97838517 DT.304281 24/141 AceView cDNA sequences (see all 141): AI520660 BX106399 BQ717428 BM724689 BM312834 AI857856 AW129306 BU069138 BI916829 AA845381 AY368076 AA496082 BQ723198 AL526004 N39407 BU151008 BQ882439 BC041430 BQ889705 AI815500 AA573847 BM662588 BU785011 BQ423380
GeneLoc Exon Structure
5/16 Alternative Splicing Database (ASD) splice patterns (SP) for KIF21A (see all 16) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18 | ^ | 19a | · | 19b | ^ | 20 | ^ | 21a | · | 21b | ^ | 22a | · | 22b | ^ | 23a | · | 23b | ^ | 24 | ^ | 25 | ^ | 26a | · | 26b | ^ | 27 | ^ | 28 | ^ | 29a | · | 29b | ^ | 30a | · | 30b | ^ | 31 | ^ | 32a | · | 32b | ^ | 33 | ^ | 34a | · | 34b | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 34c | ^ | 35 | ^ | 36 | ^ | 37 | ^ | 38 |
|---|
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| SP1: | | | | | | | | | | | |
| SP2: | | | | | | | | | | | |
| SP3: | | | | | | | | | | | |
| SP4: | | | | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for KIF21A
|
Expression
for KIF21A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KIF21A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGCTATGAA
About this image
See KIF21A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KIF21A
SOURCE GeneReport for Unigene cluster: Hs.374201
SABiosciences Custom PCR Arrays for KIF21A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIF21A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KIF21A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIF21A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIF21A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF21A |
Orthologs
for KIF21A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for KIF21A gene from 6/25 species (see all 25) About this table
ENSEMBL Gene Tree for KIF21A (if available)
TreeFam Gene Tree for KIF21A (if available) |
Paralogs
for KIF21A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KIF21A gene
- KIF5C2 KIF112 KIF3B2 KIF21B2 KIF92 KIF172 KIF4B2 KIF272
- KIF3A2 KIF4A2 KIF5B2 KIF62 KIF152 CENPE2 KIF5A2 KIF72
- KIF3C2
18/31 SIMAP similar genes for KIF21A using alignment to 11 protein entries: KI21A_HUMAN (see all proteins)
(see all similar genes):DKFZp779C159 KIF21B KIF2C KIF7 KIF27 KIF17
KIF23 KLP6 KIF18A KIF1B KIF1Bbeta KIF13A
KIF5B CENPE KIF22 KIF3A KIF1A KIF5C
KIF21A for paralogs About GeneDecksing
|
Genomic Variants
for KIF21A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KIF21A (39687030 - 39837192 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for KIF21A
1 CNV: 101484
1 Indel: 60084
Human Gene Mutation Database (HGMD): KIF21A
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIF21A |
|
Disorders
/ Diseases
for KIF21A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
KIF21A for disorders About GeneDecksing
OMIM gene information: 608283
OMIM disorders: 135700
UniProtKB/Swiss-Prot: KI21A_HUMAN, Q7Z4S6
Defects in KIF21A are a cause of congenital fibrosis of extraocular muscles type 1 (CFEOM1) [MIM:135700].CFEOM encompasses several different inherited strabismus syndromes characterized by congenital restrictiveophthalmoplegia affecting extraocular muscles innervated by the oculomotor and/or trochlear nerves. CFEOM ischaracterized clinically by anchoring of the eyes in downward gaze, ptosis, and backward tilt of the head. CFEOM1individuals show an absence of the superior division of the oculomotor nerve (cranial nerve III) and correspondingoculomotor subnuclei
16  diseases for KIF21A: About MalaCardsfibrosis of extraocular muscles fibrosis of extraocular muscles, congenital, 1 congenital fibrosis of the extraocular muscles fibrosis
fibrosis of extraocular muscles, congenital, 3 renal carcinoma carcinoma enophthalmos
amblyopia hyperopia astigmatism strabismus
renal cell carcinoma ptosis schizophrenia neuronitis
5 diseases from the University of Copenhagen DISEASES database for KIF21A:Ophthalmoplegia Hyperopia Enophthalmos Amblyopia
Histidinemia 2 Novoseek disease relationships for KIF21A gene About this table
GeneTests: KIF21A
Congenital Fibrosis of the Extraocular Muscles
Genetic Association Database (GAD): KIF21A
Human Genome Epidemiology (HuGE) Navigator: KIF21A (1 document)
Export disorders for KIF21A gene to outside databases
|
Publications
for KIF21A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KIF21A gene, integrated from 9 sources (see all 53):
(articles sorted by number of sources associating them with KIF21A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel KIF21A mutation in a patient with congenital fibrosis of the extraocular muscles and Marcus Gunn jaw-winking phenomenon. (PubMed id 16157808)1, 2, 9 Yamada K.... Engle E.C. (2005)
- Mutation analysis of KIF21A in congenital fibrosis of the extraocular muscles (CFEOM) patients. (PubMed id 15621876)1, 4, 9 Tiab L....Schorderet D. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Heterozygous mutations of the kinesin KIF21A in congenital fibrosis of the extraocular muscles type 1 (CFEOM1). (PubMed id 14595441)1, 2 Yamada K.... Engle E.C. (2003)
- Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2 Nagase T.... Ohara O. (2000)
- Antigens recognized by autologous antibody in patients with renal- cell carcinoma. (PubMed id 10508479)1, 2 Scanlan M.J....Old L.J. (1999)
- Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B. (PubMed id 10225949)1, 3 Marszalek J.R....Goldstein L.S. (1999)
- Recurrent mutation of the KIF21A gene in Japanese patients with congenital fibrosis of the extraocular muscles. (PubMed id 16365788)1, 9 Shimizu S....Maruo T. (2005)
- A major mutation of KIF21A associated with congenital fibrosis of the extraocular muscles type 1 (CFEOM1) enhances translocation of Kank1 to the membrane. (PubMed id 19559006)1, 9 Kakinuma N. and Kiyama R. (2009)
|
External Searches for KIF21A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing KIF21A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KIF21A gene
(According to HUGE)
About This Section
| |
Specialized Databases showing KIF21A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for KIF21A | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/KIF21A |
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About This Section
| Patent Information for KIF21A gene:
Search GeneIP for patents involving KIF21A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for KIF21A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KIF21A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KIF21A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIF21A | | | OriGene Protein Over-expression Lysate for KIF21A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KIF21A | | OriGene 3'-UTR Clone for KIF21A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIF21A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIF21A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for KIF21A | | OriGene Custom Protein Services for KIF21A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIF21A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIF21A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIF21A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIF21A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIF21A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIF21A |
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| | | | Search Tocris compounds for KIF21A |
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 | | | KIF21A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF21A |
|  |  |  | | | | Search ThermoFisher Antibodies for KIF21A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIF21A |
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