Aliases for KIF1B Gene
External Ids for KIF1B Gene
Previous HGNC Symbols for KIF1B Gene
Previous GeneCards Identifiers for KIF1B Gene
This gene encodes a motor protein that transports mitochondria and synaptic vesicle precursors. Mutations in this gene cause Charcot-Marie-Tooth disease, type 2A1. [provided by RefSeq, Jul 2008]
GeneCards Summary for KIF1B Gene
KIF1B (Kinesin Family Member 1B) is a Protein Coding gene. Diseases associated with KIF1B include Charcot-Marie-Tooth Disease, Type 2A1 and Pheochromocytoma. Among its related pathways are Vesicle-mediated transport and Factors involved in megakaryocyte development and platelet production. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF1A.
UniProtKB/Swiss-Prot for KIF1B Gene
Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility. Isoform 2 is required for induction of neuronal apoptosis.