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Aliases for KIF19 Gene

Aliases for KIF19 Gene

  • Kinesin Family Member 19 2 3
  • Kinesin-Like Protein KIF19 3
  • KIF19A 3

External Ids for KIF19 Gene

Previous GeneCards Identifiers for KIF19 Gene

  • GC17P069834
  • GC17P072321

Summaries for KIF19 Gene

GeneCards Summary for KIF19 Gene

KIF19 (Kinesin Family Member 19) is a Protein Coding gene. GO annotations related to this gene include microtubule binding and ATP-dependent microtubule motor activity, plus-end-directed. An important paralog of this gene is KIF14.

UniProtKB/Swiss-Prot for KIF19 Gene

  • Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIF19 Gene

Genomics for KIF19 Gene

Regulatory Elements for KIF19 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for KIF19 Gene

74,326,210 bp from pter
74,355,820 bp from pter
29,611 bases
Plus strand

Genomic View for KIF19 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KIF19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIF19 Gene

Proteins for KIF19 Gene

  • Protein details for KIF19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Kinesin-like protein KIF19
    Protein Accession:
    Secondary Accessions:
    • A6NLG2
    • B7ZKR1
    • Q52M87
    • Q8N1X8
    • Q8TAB6

    Protein attributes for KIF19 Gene

    998 amino acids
    Molecular mass:
    111332 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for KIF19 Gene


neXtProt entry for KIF19 Gene

Proteomics data for KIF19 Gene at MOPED

Post-translational modifications for KIF19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIF19 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for KIF19 Gene

Domains for KIF19 Gene

Gene Families for KIF19 Gene

  • KIF :Kinesins

Protein Domains for KIF19 Gene

Suggested Antigen Peptide Sequences for KIF19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q2TAC6
  • Contains 1 kinesin motor domain.
  • Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
genes like me logo Genes that share domains with KIF19: view

Function for KIF19 Gene

Molecular function for KIF19 Gene

UniProtKB/Swiss-Prot Function:
Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips.

Gene Ontology (GO) - Molecular Function for KIF19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003777 microtubule motor activity --
GO:0005524 ATP binding IEA --
GO:0008017 microtubule binding IEA --
GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed ISS --
GO:0016887 ATPase activity IBA --
genes like me logo Genes that share ontologies with KIF19: view
genes like me logo Genes that share phenotypes with KIF19: view

Animal Models for KIF19 Gene

MGI Knock Outs for KIF19:

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targeting and HOMER Transcription for KIF19 Gene

Localization for KIF19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KIF19 Gene

Cytoplasm, cytoskeleton. Cell projection, cilium. Note=Localizes to cilia tips. {ECO:0000250}.

Gene Ontology (GO) - Cellular Components for KIF19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005871 kinesin complex IBA --
GO:0005874 microtubule IEA --
GO:0005929 cilium ISS --
genes like me logo Genes that share ontologies with KIF19: view

No data available for Subcellular locations from COMPARTMENTS for KIF19 Gene

Pathways for KIF19 Gene

SuperPathways for KIF19 Gene

No Data Available

Interacting Proteins for KIF19 Gene

Gene Ontology (GO) - Biological Process for KIF19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006200 obsolete ATP catabolic process --
GO:0007018 microtubule-based movement IBA --
GO:0008152 metabolic process IEA --
GO:0060404 axonemal microtubule depolymerization ISS --
GO:0070462 plus-end specific microtubule depolymerization ISS --
genes like me logo Genes that share ontologies with KIF19: view

No data available for Pathways by source for KIF19 Gene

Transcripts for KIF19 Gene

Unigene Clusters for KIF19 Gene

Kinesin family member 19:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KIF19

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIF19 Gene

No ASD Table

Relevant External Links for KIF19 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for KIF19 Gene

mRNA expression in normal human tissues for KIF19 Gene

mRNA differential expression in normal tissues according to GTEx for KIF19 Gene

This gene is overexpressed in Nerve - Tibial (17.0) and Spleen (4.1).

Protein differential expression in normal tissues for KIF19 Gene

This gene is overexpressed in Cervix (57.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for KIF19 Gene

SOURCE GeneReport for Unigene cluster for KIF19 Gene Hs.372773

genes like me logo Genes that share expressions with KIF19: view

Expression partners for KIF19 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for KIF19 Gene

Orthologs for KIF19 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for KIF19 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia KIF19 35
  • 84.45 (n)
  • 79.64 (a)
KIF19 36
  • 79 (a)
(Canis familiaris)
Mammalia KIF19 35
  • 90.2 (n)
  • 90.57 (a)
KIF19 36
  • 90 (a)
(Mus musculus)
Mammalia Kif19a 35
  • 86.76 (n)
  • 89.77 (a)
Kif19a 16
Kif19a 36
  • 90 (a)
(Pan troglodytes)
Mammalia KIF19 35
  • 94.95 (n)
  • 93.64 (a)
-- 36
  • 21 (a)
(Rattus norvegicus)
Mammalia Kif19 35
  • 84.71 (n)
  • 87.22 (a)
(Monodelphis domestica)
Mammalia KIF19 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia KIF19 36
  • 62 (a)
(Gallus gallus)
Aves KIF19 36
  • 61 (a)
(Anolis carolinensis)
Reptilia KIF19 36
  • 65 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia kif19 35
  • 76.18 (n)
  • 86.6 (a)
(Danio rerio)
Actinopterygii kif19 35
  • 64.35 (n)
  • 63.87 (a)
kif19 36
  • 60 (a)
fruit fly
(Drosophila melanogaster)
Insecta Kif19A 35
  • 53.34 (n)
  • 45.82 (a)
Kif19A 36
  • 39 (a)
(Caenorhabditis elegans)
Secernentea klp-13 35
  • 48.03 (n)
  • 41.48 (a)
klp-13 36
  • 36 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes KIP3 36
  • 26 (a)
Species with no ortholog for KIF19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for KIF19 Gene

Gene Tree for KIF19 (if available)
Gene Tree for KIF19 (if available)

Paralogs for KIF19 Gene

Selected SIMAP similar genes for KIF19 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with KIF19: view

Variants for KIF19 Gene

Sequence variations from dbSNP and Humsavar for KIF19 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs747321 -- 74,343,918(+) GGGAA(C/T)GGGGA intron-variant
rs872507 -- 74,353,875(+) TAATC(A/T)CTGTA intron-variant
rs877791 -- 74,335,799(+) GGGGG(G/T)GCTGT intron-variant
rs1010161 -- 74,341,512(-) GAGCA(A/G)AGCAC intron-variant
rs1010773 -- 74,339,189(+) GCCCC(A/G)CCCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KIF19 Gene

Variant ID Type Subtype PubMed ID
dgv12e196 CNV Duplication 17116639
dgv372n27 CNV Gain 19166990
nsv517569 CNV Gain+Loss 19592680
esv2751770 CNV Gain 17911159
nsv509673 CNV Insertion 20534489
nsv833538 CNV Gain 17160897
nsv833539 CNV Loss 17160897
esv33995 CNV Loss 17666407
esv2657435 CNV Deletion 23128226
esv2716214 CNV Deletion 23290073
esv2716215 CNV Deletion 23290073
esv2716216 CNV Deletion 23290073
nsv908741 CNV Loss 21882294
esv2660286 CNV Deletion 23128226
esv29259 CNV Loss 19812545
esv2716217 CNV Deletion 23290073
nsv908742 CNV Loss 21882294

Relevant External Links for KIF19 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIF19 Gene

Disorders for KIF19 Gene

Relevant External Links for KIF19

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for KIF19 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for KIF19 Gene

Publications for KIF19 Gene

  1. All kinesin superfamily protein, KIF, genes in mouse and human. (PMID: 11416179) Miki H. … Hirokawa N. (Proc. Natl. Acad. Sci. U.S.A. 2001) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 3 4
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48

Products for KIF19 Gene

Sources for KIF19 Gene

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