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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KIF18A Gene

protein-coding   GIFtS: 58
GCID: GC11M028042

Kinesin Family Member 18A

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Kinesin Family Member 18A1 2
MS-KIF18A2 3
Kinesin-Like Protein KIF18A2
Marrow Stromal KIF18A3

External Ids:    HGNC: 294411   Entrez Gene: 819302   Ensembl: ENSG000001216217   OMIM: 6112715   UniProtKB: Q8NI773   

Export aliases for KIF18A gene to outside databases

Previous GC identifers: GC11M027998 GC11M027740


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for KIF18A Gene:
KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use
hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 (PubMed
15878648)).(supplied by OMIM, Aug 2008)

GeneCards Summary for KIF18A Gene: 
KIF18A (kinesin family member 18A) is a protein-coding gene. Diseases associated with KIF18A include asbestosis, and sertoli cell-only syndrome, and among its related super-pathways are Mitotic Anaphase and Mitotic Prometaphase. GO annotations related to this gene include ubiquitin binding and actin binding. An important paralog of this gene is KIF22.

UniProtKB/Swiss-Prot: KI18A_HUMAN, Q8NI77
Function: Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the
amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome
movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE
levels at kinetochores during chromosome congression

Gene Wiki entry for KIF18A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_009237.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KIF18A gene promoter:
         LHX3b/Lhx3b   AML1a   p53   SREBP-1c   POU6F1 (c2)   Nkx2-5   SREBP-1b   SREBP-1a   Chx10   LHX3a/Lhx3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKIF18A promoter sequence
   Search SABiosciences Chromatin IP Primers for KIF18A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIF18A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p14.1   Ensembl cytogenetic band:  11p14.1   HGNC cytogenetic band: 11p14.1

KIF18A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIF18A gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M028042:  view genomic region     (about GC identifiers)

Start:
28,042,163 bp from pter      End:
28,129,855 bp from pter
Size:
87,693 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KI18A_HUMAN, Q8NI77 (See protein sequence)
Recommended Name: Kinesin-like protein KIF18A  
Size: 898 amino acids; 102281 Da
Subunit: Interacts with CENPE and ESR1
Subcellular location: Cell projection, ruffle. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing
center, centrosome
1 PDB 3D structure from and Proteopedia for KIF18A:
3LRE (3D)    
Secondary accessions: Q4VPE3 Q86VS5 Q9H0F3

Explore the universe of human proteins at neXtProt for KIF18A: NX_Q8NI77

Explore proteomics data for KIF18A at MOPED 

Post-translational modifications:

  • UniProtKB: Glycosylated
  • UniProtKB: Ubiquitinated
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NI77

  • KIF18A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    KIF18A Protein Expression
    REFSEQ proteins: NP_112494.3  
    ENSEMBL proteins: 
     ENSP00000263181  
    Reactome Protein details: Q8NI77
    Human Recombinant Protein Products for KIF18A: 
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    Cloud-Clone Corp. Proteins for KIF18A 

    Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001726ruffle IDA17006958
    GO:0005634nucleus IDA17006958
    GO:0005737cytoplasm IDA--
    GO:0005815microtubule organizing center IEA--
    GO:0005828kinetochore microtubule IDA17346968

    KIF18A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    KIF: Kinesins

    3 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR001752 Kinesin_motor_dom
     IPR019821 Kinesin_motor_CS

    Graphical View of Domain Structure for InterPro Entry Q8NI77

    ProtoNet protein and cluster: Q8NI77

    1 Blocks protein domain: IPB001752 Kinesin

    UniProtKB/Swiss-Prot: KI18A_HUMAN, Q8NI77
    Similarity: Belongs to the kinesin-like protein family
    Similarity: Contains 1 kinesin-motor domain


    KIF18A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KI18A_HUMAN, Q8NI77
    Function: Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the
    amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome
    movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE
    levels at kinetochores during chromosome congression
    Induction: By estrogen

         Gene Ontology (GO): 5/9 molecular function terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003777microtubule motor activity ----
    GO:0003779actin binding IPI18680169
    GO:0005515protein binding IPI17006958
    GO:0005524ATP binding IEA--
    GO:0008017microtubule binding IDA18680169
         
    KIF18A for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for KIF18A:
     Cell cycle / mitosis defect  Decreased G3BP1 protein expres 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for KIF18A About   (see all 7)                                                                                              See pathways by source

    SuperPathContained pathways About
    1M Phase
    Mitotic Anaphase0.94
    M Phase0.88
    Separation of Sister Chromatids0.94
    Mitotic M-M/G1 phases0.88
    Mitotic Metaphase and Anaphase0.94
    2Resolution of Sister Chromatid Cohesion
    Resolution of Sister Chromatid Cohesion0.93
    Mitotic Prometaphase0.93
    3Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84
    4Immune System
    Immune System0.56
    Adaptive Immune System0.56
    5MHC class II antigen presentation
    MHC class II antigen presentation0.32
    Kinesins0.32

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/15        Reactome Pathways for KIF18A (see all 15)
        Hemostasis
    Mitotic Metaphase and Anaphase
    Mitotic Prometaphase
    Resolution of Sister Chromatid Cohesion
    Mitotic Anaphase



    KIF18A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIF18A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/105 Interacting proteins for KIF18A (Q8NI772, 3 ENSP000002631814) via UniProtKB, MINT, STRING, and/or I2D (see all 105)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPP1CAP621362, 3MINT-62197 I2D: score=3 
    ANAPC4Q9UJX52MINT-8412937 MINT-8412957
    NFKBIBQ156533I2D: score=1 
    NEK2P519552MINT-8412937
    AURKBENSP000003139504STRING: ENSP00000313950
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0007018microtubule-based movement TAS--
    GO:0007019microtubule depolymerization IDA17346968
    GO:0007080mitotic metaphase plate congression IDA17346968
    GO:0007596blood coagulation TAS--

    KIF18A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KIF18A (KI18A)

    Search CenterWatch for drugs/clinical trials and news about KIF18A / KI18A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for KIF18A gene: 
    NM_031217.3  

    Unigene Cluster for KIF18A:

    Kinesin family member 18A
    Hs.301052  [show with all ESTs]
    Unigene Representative Sequence: NM_031217
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263181(uc001msc.2) ENST00000533466 ENST00000531047 ENST00000526288(uc001msd.3)

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    Inhib. RNA
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    Additional mRNA sequence: 

    AB062483.1 AK093850.1 AK312576.1 AL136819.1 AY791349.1 BC026090.1 BC035917.1 BC048347.2 

    6 DOTS entries:

    DT.402985  DT.97813038  DT.100749771  DT.95172254  DT.91761488  DT.95172252 

    24/96 AceView cDNA sequences (see all 96):

    AL136819 BM468071 BM466083 AA765523 AI741379 BM972993 AA252411 AI185060 
    AW770226 AK093850 AI953706 AA355936 BM971094 AX748337 BC048347 BP355503 
    AI056037 AI933806 AL523812 AI027214 BP355504 AA252366 CR610087 BU161346 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for KIF18A (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^
    SP1:                          -                 -     -                                               -                                                         
    SP2:                                            -     -                                                                                                         
    SP3:                                                                                                                                                            
    SP4:                    -     -                                                                                                                                 
    SP5:                    -     -                                                                                                                                 

    ExUns: 18
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for KIF18A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KIF18A expression in normal human tissues (normalized intensities)      KIF18A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGGCAGCTT
    KIF18A Expression
    About this image


    KIF18A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Ovary (Reproductive System)
             XX Germ Cells Ovigerous Cord
     
     Gonad
             XX Germ Cells Ovigerous Cord
     
     Brain (Nervous System)
             brain/midbrain   
     
     Testis (Reproductive System)

    See KIF18A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KIF18A

    SOURCE GeneReport for Unigene cluster: Hs.301052
        SABiosciences Custom PCR Arrays for KIF18A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF18A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for KIF18A gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kif18a1 , 5 kinesin family member 18A1, 5 81.57(n)1
    76.86(a)1
      2 (56.55 cM)5
    2284211  NM_139303.11  NP_647464.11 
     1092807385 
    chicken
    (Gallus gallus)
    Aves KIF18A1 kinesin family member 18A 67.57(n)
    63.04(a)
      421607  NM_001199426.1  NP_001186355.1 
    lizard
    (Anolis carolinensis)
    Reptilia KIF18A6
    kinesin family member 18A
    56(a)
    1 ↔ 1
    GL343314.1(667873-723706)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3986502 hypothetical protein LOC398650 76.03(n)    BC054210.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc559952 hypothetical protein MGC55995 75(n)   393209  BC047799.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Klp67A6
    Kinesin-like protein at 67A
    31(a)
    1 → many
    3L(9355736-9360051)


    ENSEMBL Gene Tree for KIF18A (if available)
    TreeFam Gene Tree for KIF18A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KIF18A gene
    KIF222  KIF2A2  KIF242  KIF2B2  KIF18B2  KIF2C2  KIF192  
    8 SIMAP similar genes for KIF18A using alignment to 2 protein entries:     KI18A_HUMAN (see all proteins):
    KIF18B    KIF6    KIF19    KIF5C    KIF21A    KIF5B
    KIF3A    KIF5A

    KIF18A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1305 SNPs in KIF18A are shown (see all 1305)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs344095391,2
    C--27763785(+) AAAAC-/AAAAAC
            
    CAAAT
    1 -- int11Minor allele frequency- AAAAAC:0.00NA 2
    rs57906811,2
    C--27804918(+) ATATA-/TAATCAA 1 -- int11Minor allele frequency- TA:0.00NA 2
    rs1892912591,2
    --28041752(+) CCACGC/TATCAG 1 -- ds50010--------
    rs110301851,2
    C,F,A--28041904(+) TCTAGC/TTGCAA 1 -- ds50017Minor allele frequency- T:0.32NA WA CSA EA 250
    rs122736311,2
    C,F,A--28042135(+) GTATGA/TAAGGG 1 -- ds500113Minor allele frequency- T:0.43NA WA CSA EA 504
    rs1819933461,2
    --28042370(+) TAATTC/TTACCA 1 -- ut310--------
    rs1399723261,2
    C,F--28042799(+) TGCTTG/AGATTT 2 /P /L mis11Minor allele frequency- A:0.01NA 2924
    rs1432583121,2
    C--28042804(+) GGATTG/TATTTT 2 I syn10--------
    rs1998515541,2
    C--28042852(+) AGATGC/TATAAA 1 -- int10--------
    rs79396301,2
    C,F--28042916(+) GACCAT/CAGAAA 1 -- int13Minor allele frequency- C:0.16WA CSA 122

    HapMap Linkage Disequilibrium report for KIF18A (28042163 - 28129855 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for KIF18A:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2744299CNV Deletion23290073
    nsv897150CNV Loss21882294
    nsv832096CNV Loss17160897
    esv9041CNV Gain19470904
    nsv897149CNV Gain21882294


    Human Gene Mutation Database (HGMD): KIF18A
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611271    OMIM disorders: --

    3 diseases for KIF18A:    About MalaCards
    asbestosis    sertoli cell-only syndrome    colon cancer


    KIF18A for disorders           About GeneDecksing

    Genetic Association Database (GAD): KIF18A

    Export disorders for KIF18A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KIF18A gene, integrated from 9 sources (see all 35):
    (articles sorted by number of sources associating them with KIF18A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
    2. Defects in chromosome congression and mitotic progression in KIF18A- deficient cells are partly mediated through impaired functions of CENP-E. (PubMed id 19625775)1, 2 Huang Y.... Dai W. (2009)
    3. The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment. (PubMed id 18267093)1, 2 Stumpff J.... Wordeman L. (2008)
    4. New insights on cellular distribution, microtubule interactions and post-translational modifications of MS-KIF18A. (PubMed id 18680169)1, 2 Zusev M. and Benayahu D. (2008)
    5. The human kinesin Kif18A is a motile microtubule depolymerase essential for chromosome congression. (PubMed id 17346968)1, 2 Mayr M.I....Mayer T.U. (2007)
    6. MS-KIF18A, a kinesin, is associated with estrogen receptor. (PubMed id 17006958)1, 2 Luboshits G. and Benayahu D. (2007)
    7. MS-KIF18A, new kinesin; structure and cellular expression. (PubMed id 15878648)1, 2 Luboshits G. and Benayahu D. (2005)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Mechanisms controlling the temporal degradation of Nek 2A and Kif18A by the APC/C-Cdc20 complex. (PubMed id 23288039)1 Sedgwick G.G....Nilsson J. (2013)
    10. Kif18A and chromokinesins confine centromere movements via microtubule growth suppression and spatial control of kinetochore tension. (PubMed id 22595673)1 Stumpff J....Wordeman L. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 81930 HGNC: 29441 AceView: KIF18A Ensembl:ENSG00000121621 euGenes: HUgn81930
    ECgene: KIF18A H-InvDB: KIF18A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KIF18A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for KIF18A gene:
    Search GeneIP for patents involving KIF18A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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