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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KIF14 Gene

protein-coding   GIFtS: 54
GCID: GC01M200521

kinesin family member 14
 Explore 9 diseases affiliated with
KIF14 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for KIF14    

Aliases
for KIF14 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Kinesin Family Member 141 2
KIAA00421 3 5
Kinesin-Like Protein KIF142

External Ids:    HGNC: 191811   Entrez Gene: 99282   Ensembl: ENSG000001181937   OMIM: 6112795   UniProtKB: Q150583   

Export aliases for KIF14 gene to outside databases

Previous GC identifers: GC01M198251 GC01M195979 GC01M196987 GC01M197809 GC01M197252 GC01M198787 GC01M171687


Summaries
for KIF14 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for KIF14:
KIF14 is a member of the kinesin superfamily of microtubule-associated motors (see MIM 148760) that play important
roles in intracellular transport and cell division (Nakagawa et al., 1997 (PubMed 9275178)).(supplied by OMIM, Mar
2008)

UniProtKB/Swiss-Prot: KIF14_HUMAN, Q15058
Function: Plays an essential role in cytokinesis

Gene Wiki entry for KIF14


Genomic Views
for KIF14 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KIF14 gene promoter:
         HOXA9   HOXA9B   TBP   AML1a   ATF-2   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: KIF14 promoter sequence
   Search SABiosciences Chromatin IP Primers for KIF14

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIF14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.1   Ensembl cytogenetic band:  1q32.1   HGNC cytogenetic band: 1q32.1

KIF14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIF14 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M200521:  view genomic region     (about GC identifiers)

Start:
 200,520,625 bp from pter      End:
 200,589,862 bp from pter
Size:
 69,238 bases      Orientation:
 minus strand

Proteins
for KIF14 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: KIF14_HUMAN, Q15058 (See protein sequence)
Recommended Name: Kinesin-like protein KIF14  
Size: 1648 amino acids; 186492 Da
Subunit: Directly interacts with PRC1 within a complex also containing KIF4A, KIF20A and KIF23. Directly interacts with
CIT depending on the activation state of the kinase (stronger interaction with the kinase-dead form). Interacts with
ARRB2; the interaction is detected in the nucleus upon OR1D2 stimulation
Subcellular location: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Nuclear localization observed during
interphase in PubMed:16431929 or triggered by entry into mitosis in PubMed:16648480. Cytoplasmic in interphase
(PubMed:16648480) and metaphase cells (PubMed:16431929). From prophase to metaphase, accumulates at the developing
spindle poles and their associated microtubules. During anaphase, accumulates at the spindle midzone. Localization to
the central spindle and midbody during anaphase is dependent upon PRC1 and CIT presence. In cells ready to undergo
abscission, concentrates at the contractile ring
Developmental stage: Up-regulated in cells progressing through G2/M phase
Sequence caution: Sequence=BAA05392.2; Type=Erroneous initiation;
Secondary accessions: Q14CI8 Q4G0A5 Q5T1W3

Explore the universe of human proteins at neXtProt for KIF14: NX_Q15058

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q15058

    • KIF14 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_055690.1  
    ENSEMBL proteins: 
     ENSP00000356319  

    Human Recombinant Protein Products: 
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    Uscn Proteins for KIF14

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0005819spindle IEA--
    GO:0005874microtubule IEA--
    GO:0005875microtubule associated complex IEA--


    KIF14 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for KIF14

    Protein Domains /
    Families
    for KIF14 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    KIF14 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR008984 SMAD_FHA_domain
     IPR001752 Kinesin_motor_dom
     IPR000253 FHA_dom
     IPR019821 Kinesin_motor_CS

    Graphical View of Domain Structure for InterPro Entry Q15058

    ProtoNet protein and cluster: Q15058

    2 Blocks protein families:
    IPB000253 Forkhead-associated (FHA)
    IPB001752 Kinesin


    UniProtKB/Swiss-Prot: KIF14_HUMAN, Q15058
    Similarity: Belongs to the kinesin-like protein family
    Similarity: Contains 1 FHA domain
    Similarity: Contains 1 kinesin-motor domain


    Function
    for KIF14 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: KIF14_HUMAN, Q15058
    Function: Plays an essential role in cytokinesis

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: KIF14 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003777microtubule motor activity IEA--
    GO:0005515protein binding IPI16820410
    GO:0005524ATP binding IEA--


    KIF14 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for KIF14:
     Increased 8N DNA content  Synthetic lethal with Ras 


    Pathways & Interactions
    for KIF14 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIF14

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/8 Interacting proteins for KIF14 (Q150582, 3 ENSP000003563194) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SVILO954253, ENSP000003481284I2D: score=1 STRING: ENSP00000348128
    SUMO1P631653, ENSP000003760764I2D: score=1 STRING: ENSP00000376076
    RIPK2O433533, ENSP000002207514I2D: score=1 STRING: ENSP00000220751
    PSTPIP1O435863, ENSP000003689144I2D: score=1 STRING: ENSP00000368914
    SEPT8Q925993I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007018microtubule-based movement IEA--


    KIF14 for ontologies           About GeneDecksing



    Drugs & Compounds
    for KIF14 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for KIF14
    Search CenterWatch for drugs/clinical trials and news about KIF14 

    Transcripts
    for KIF14 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for KIF14 gene: 
    NM_014875.2  

    Unigene Cluster for KIF14:

    Kinesin family member 14
    Hs.3104  [show with all ESTs]
    Unigene Representative Sequence: NM_014875
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000367350(uc010ppj.1 uc010ppk.1)

    miRNA
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    hsa-miR-3671 hsa-miR-767-3p hsa-miR-130b* hsa-miR-485-3p hsa-miR-1976 hsa-miR-664 hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmid: KIF14 3' UTR sequence
    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    BC098582.1 BC113742.1 BC144068.1 D26361.1 

    1 DOTS entry:

    DT.406343 

    24/31 AceView cDNA sequences (see all 31):

    BQ425495 CB409937 BM480026 AA668857 D26361 BE644769 BG615572 BE888525 
    AA668879 CD652057 AA477501 BX646345 BF435707 AA479873 AW075554 AW183154 
    CB136970 CD642678 BX099509 BP359286 BX426204 BX414768 BQ921291 BE874348 

    GeneLoc Exon Structure


    Expression
    for KIF14 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KIF14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AATAAATCTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    KIF14 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ progenitor E44 (Embryonic Progenitor Cell)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See KIF14 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KIF14

    SOURCE GeneReport for Unigene cluster: Hs.3104
        SABiosciences Custom PCR Arrays for KIF14
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    In Situ
    Assay Products:     
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    Orthologs
    for KIF14 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for KIF14 gene from 6/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves KIF141 kinesin family member 14 64.81(n)
    57.07(a)    		   424347  XM_422190.3  XP_422190.3 
    lizard
    (Anolis carolinensis)    		 Reptilia KIF146
    KIF13B6
    		 --
    		 66(a)
    10(a)
    		 1 ↔ 1
    possible ortholog
    		 GL343211.1(1829748-1857792)
    4(40287123-40371607)
    African clawed frog
    (Xenopus laevis)    		 Amphibia BJ063135.12   -- 75.54(n)    BJ063135.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii kif141 kinesin family member 14 59.58(n)
    57.73(a)    		   562052  NM_001044976.1  NP_001038441.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta neb1 nebbish 45.28(n)
    39.84(a)    		   35293  NM_057469.4  NP_476817.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea klp-196
    		 Kinesin-Like Protein family member (klp-19)
    		 16(a)
    		 possible ortholog
    		 III(13302642-13307158)


    ENSEMBL Gene Tree for KIF14 (if available)
    TreeFam Gene Tree for KIF14 (if available) 

    Paralogs
    for KIF14 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KIF14 gene
    KIF18A2  KIF1C2  KIF16B2  KIF1B2  KIF192  KIF222  KIF13B2  KIF1A2  
    KIF13A2  KIF122  KIF18B2  
    1 SIMAP similar gene for KIF14 using alignment to 1 protein entry:     KIF14_HUMAN:
    KIF1C

    KIF14 for paralogs           About GeneDecksing



    Genomic Variants
    for KIF14 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1346 NCBI SNPs in KIF14 are shown (see all 1346)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1429258921,2
    		--200520250(+) ATGAGA/GTGGGT 1 -- int10--------
    rs749771881,2
    		--200520256(+) TGGGTA/GTTACT 1 -- int13Minor allele frequency- G:0.23CSA WA NA 239
    rs1466062741,2
    		--200520300(+) ACAGTA/GACATG 1 -- int10--------
    rs784249001,2
    		F,--200520334(+) CAGTCC/TAGCTG 1 -- int11Minor allele frequency- T:0.04NA 120
    rs1840524171,2
    		--200520351(+) ACACTC/TCAAAC 1 -- int10--------
    rs109199731,2
    		C,F,A,H,--200520443(+) CTAAAC/GAGAGG 1 -- int117Minor allele frequency- G:0.41NA NS EA WA CSA 929
    rs1133872521,2
    		C,--200520460(+) ATGTTA/-AAAAA 1 -- int11Minor allele frequency- -:0.00CSA 2
    rs1414696961,2
    		--200520563(+) GCTATC/TCTGAA 1 -- int10--------
    rs1451547041,2
    		--200520621(+) ACCACA/GAAGCA 1 -- int10--------
    rs1143391131,2
    		F,--200520698(+) TCCAAT/CAGCAA 1 -- ut311Minor allele frequency- C:0.04NA 120

    HapMap Linkage Disequilibrium report for KIF14 (200520625 - 200589862 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for KIF14
         1 CNV: 2344

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    Disorders / Diseases
    for KIF14 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    KIF14 for disorders           About GeneDecksing

    OMIM gene information: 611279    OMIM disorders: --

    9 diseases for KIF14:    About MalaCards
    laryngitis    laryngeal carcinoma    retinoblastoma    breast cancer
    pancreatic carcinoma    lung cancer    pancreatitis    carcinoma
    malaria

    3 Novoseek disease relationships for KIF14 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoblastoma 34.7 10 17962437 (6)
    breast cancer 8.52 1 16570270 (1)
    tumors 0 10 17962437 (5), 17099872 (1)

    Human Genome Epidemiology (HuGE) Navigator: KIF14 (1 document)

    Export disorders for KIF14 gene to outside databases

    Publications
    for KIF14 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KIF14 gene, integrated from 9 sources (see all 45):
    (articles sorted by number of sources associating them with KIF14)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7584044)1, 2, 3 Nomura N....Tabata S. (1994)
    2. The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells. (PubMed id 17203973)1, 2 Vasilescu J.... Figeys D. (2007)
    3. Novel function of beta-arrestin2 in the nucleus of mature spermatozoa. (PubMed id 16820410)1, 2 Neuhaus E.M.... Hatt H. (2006)
    4. RNA interference-mediated silencing of mitotic kinesin KIF14 disrupts cell cycle progression and induces cytokinesis failure. (PubMed id 16648480)1, 2 Carleton M....Linsley P.S. (2006)
    5. KIF14 and citron kinase act together to promote efficient cytokinesis. (PubMed id 16431929)1, 2 Gruneberg U.... Barr F.A. (2006)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    7. High expression of KIF14 in retinoblastoma: association with older age at diagnosis. (PubMed id 17962437)1, 9 Madhavan J....Kumaramanickavel G. (2007)
    8. Profiling genomic copy number changes in retinoblastoma beyond loss of RB1. (PubMed id 17099872)1, 9 Bowles E....Gallie B.L. (2007)
    9. Metal-proteinase ADAM12, kinesin 14 and checkpoint su ppressor 1 as new molecular markers of laryngeal carcinoma. (PubMed id 19609547)1, 9 Markowski J....Jarzab B. (2009)
    10. Consensus transcriptome signature of perineural invas ion in pancreatic carcinoma. (PubMed id 19509238)1, 9 Abiatari I....Kleeff J. (2009)

    External Searches for KIF14 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing KIF14 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9928 HGNC: 19181 AceView: KIF14 Ensembl:ENSG00000118193 euGenes: HUgn9928
    ECgene: KIF14 H-InvDB: KIF14

    Other Databases showing KIF14 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA0042

    Specialized Databases showing KIF14 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KIF14 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for KIF14 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
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    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    		Patent Information for KIF14 gene:
    Search GeneIP for patents involving KIF14

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