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KIF13B Gene

protein-coding   GIFtS: 55
GCID: GC08M028924

Kinesin Family Member 13B

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Kinesin Family Member 13B1 2     Guanylate Kinase Associated Kinesin2
GAKIN2 3 5     Kinesin 13B2
Kinesin-Like Protein GAKIN2 3     Kinesin-Like Protein KIF13B2
KIAA06393 5     

External Ids:    HGNC: 144051   Entrez Gene: 233032   Ensembl: ENSG000001978927   OMIM: 6073505   UniProtKB: Q9NQT83   

Export aliases for KIF13B gene to outside databases

Previous GC identifers: GC08M029510 GC08M028745 GC08M028946 GC08M028980 GC08M027469


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KIF13B Gene:
KIF13B (kinesin family member 13B) is a protein-coding gene. GO annotations related to this gene include microtubule motor activity and protein kinase binding. An important paralog of this gene is KIF18A.

UniProtKB/Swiss-Prot: KI13B_HUMAN, Q9NQT8
Function: Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the
formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and
associated protein complexes




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NT_167187.2  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KIF13B gene promoter:
         HSF1 (long)   CUTL1   AP-2gamma   Meis-1b   HSF1short   AP-2beta   Meis-1a   AP-2alpha   AP-2alphaA   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidKIF13B promoter sequence
   Search Chromatin IP Primers for KIF13B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KIF13B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p12   Ensembl cytogenetic band:  8p12   HGNC cytogenetic band: 8p21

KIF13B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIF13B gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M028924:  view genomic region     (about GC identifiers)

Start:
28,924,795 bp from pter      End:
29,120,641 bp from pter
Size:
195,847 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: KI13B_HUMAN, Q9NQT8 (See protein sequence)
Recommended Name: Kinesin-like protein KIF13B  
Size: 1826 amino acids; 202789 Da
Subunit: Binds to DLG1 and DLG4. Interacts (when phosphorylated at Ser-1381 and Ser-1410) with 14-3-3
Sequence caution: Sequence=BAA31614.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;
4 PDB 3D structures from and Proteopedia for KIF13B:
2COW (3D)        3FM8 (3D)        3GBJ (3D)        3MDB (3D)    
Secondary accessions: F8VPJ2 O75134 Q9BYJ6

Explore the universe of human proteins at neXtProt for KIF13B: NX_Q9NQT8

Explore proteomics data for KIF13B at MOPED

Post-translational modifications: 

  • Phosphorylated at Ser-1381 and Ser-1410 by MARK2, promoting interaction with 14-3-3 and inhibiting
    microtubule-dependent accumulation and formation of axons1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KIF13B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056069.2  
    ENSEMBL proteins: 
     ENSP00000427900   ENSP00000429106   ENSP00000429027   ENSP00000429201   ENSP00000431006  
     ENSP00000384054  

    KIF13B Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for KIF13B

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    KIF: Kinesins

    Selected InterPro protein domains (see all 9):
     IPR008984 SMAD_FHA_domain
     IPR022140 KIF1B
     IPR022164 Kinesin-like
     IPR027417 P-loop_NTPase
     IPR000938 CAP-Gly_domain

    Graphical View of Domain Structure for InterPro Entry Q9NQT8

    ProtoNet protein and cluster: Q9NQT8

    3 Blocks protein domains:
    IPB000253 Forkhead-associated (FHA)
    IPB000938 CAP-Gly domain
    IPB001752 Kinesin


    UniProtKB/Swiss-Prot: KI13B_HUMAN, Q9NQT8
    Similarity: Belongs to the kinesin-like protein family
    Similarity: Contains 1 CAP-Gly domain
    Similarity: Contains 1 FHA domain
    Similarity: Contains 1 kinesin-motor domain


    Find genes that share domains with KIF13B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KI13B_HUMAN, Q9NQT8
    Function: Involved in reorganization of the cortical cytoskeleton. Regulates axon formation by promoting the
    formation of extra axons. May be functionally important for the intracellular trafficking of MAGUKs and
    associated protein complexes

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003777microtubule motor activity NAS10859302
    GO:0005515protein binding IPI10859302
    GO:0005524ATP binding IEA--
    GO:0008017microtubule binding IEA--
    GO:0019901protein kinase binding IPI10859302
         
    Find genes that share ontologies with KIF13B           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for KIF13B:
     Decreased nuclei size in G2M 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KIF13B
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    miRNA
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    miRTarBase miRNAs that target KIF13B:
    hsa-mir-335-5p (MIRT018370)

    Block miRNA regulation of human, mouse, rat KIF13B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KIF13B (see all 17):
    hsa-miR-1226 hsa-miR-520a-5p hsa-miR-29b-1* hsa-miR-3167 hsa-miR-9 hsa-miR-124 hsa-miR-2115 hsa-miR-641
    SwitchGear 3'UTR luciferase reporter plasmidKIF13B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for KIF13B
    Predesigned siRNA for gene silencing in human, mouse, rat KIF13B

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: KIF13B (NM_015254)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KIF13B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIF13B
    Addgene plasmids for KIF13B 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF13B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    KI13B_HUMAN, Q9NQT8: Cytoplasm, cytoskeleton. Cell projection, axon. Note=accumulates at the distal part of the
    microtubules in the tips of axons, but not of dendrites
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol3
    nucleus3

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA10859302
    GO:0005871kinesin complex IEA--
    GO:0005874microtubule IEA--
    GO:0030424axon IDA--

    Find genes that share ontologies with KIF13B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for KIF13B About    
    See pathways by source

    SuperPathContained pathways About
    1Arf6 signaling events
    Arf6 signaling events


    1 BioSystems Pathway for KIF13B
        Arf6 signaling events


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KIF13B
    Interactions:

        GeneGlobe Interaction Network for KIF13B

    5 Interacting proteins for KIF13B (Q9NQT81, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DLG1Q12959-21EBI-766408,EBI-357500 I2D: score=3 
    BCL6P411823I2D: score=3 
    DLG4P783523I2D: score=2 
    MARK2Q7KZI73I2D: score=2 
    TERF2Q155543I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006605protein targeting TAS10859302
    GO:0007018microtubule-based movement TAS10859302
    GO:0007165signal transduction NAS10859302
    GO:0008152metabolic process NAS10859302
    GO:0042110T cell activation NAS12496241

    Find genes that share ontologies with KIF13B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KIF13B (KI13B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KIF13B gene: 
    NM_015254.3  

    Unigene Cluster for KIF13B:

    Kinesin family member 13B
    Hs.444767  [show with all ESTs]
    Unigene Representative Sequence: NM_015254
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000524189(uc011laz.2 uc003xhh.4) ENST00000523130 ENST00000522355(uc003xhj.2)
    ENST00000521515(uc010lvf.1) ENST00000523968 ENST00000522846(uc003xhk.2)
    ENST00000404075
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KIF13B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KIF13B (see all 17):
    hsa-miR-1226 hsa-miR-520a-5p hsa-miR-29b-1* hsa-miR-3167 hsa-miR-9 hsa-miR-124 hsa-miR-2115 hsa-miR-641
    SwitchGear 3'UTR luciferase reporter plasmidKIF13B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KIF13B
    Predesigned siRNA for gene silencing in human, mouse, rat KIF13B
    Clone
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    GenScript: all cDNA clones in your preferred vector: KIF13B (NM_015254)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KIF13B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIF13B
    Addgene plasmids for KIF13B 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for KIF13B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat KIF13B
      QuantiTect SYBR Green Assays in human, mouse, rat KIF13B
      QuantiFast Probe-based Assays in human, mouse, rat KIF13B

    Additional mRNA sequence: 

    AB014539.3 AF279865.1 AK000240.1 AK129580.1 AK294837.1 AK307848.1 AL583912.1 BC005977.1 
    BC014350.1 BC028056.1 BX537898.1 

    8 DOTS entries:

    DT.454091  DT.102829454  DT.92429492  DT.100730679  DT.121467291  DT.101976336  DT.95357358  DT.97842013 

    Selected AceView cDNA sequences (see all 159):

    CA424891 CB122646 BC005977 BM670166 BQ181806 AI469865 CA748955 AI336606 
    AU185749 AA256530 AL583912 AA630040 AI308764 AI751027 AA502298 NM_015254 
    D25705 BM712094 AI857401 BM987425 BM310678 CA313993 BI007011 W73267 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KIF13B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAATGAACTA
    KIF13B Expression
    About this image


    KIF13B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Brain (Nervous System)
             Myelinating Oligodendrocyte Cells Forebrain White Matter
    KIF13B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KIF13B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.444767

    UniProtKB/Swiss-Prot: KI13B_HUMAN, Q9NQT8
    Tissue specificity: Ubiquitous

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIF13B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for KIF13B gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Kif13b1 , 5 kinesin family member 13B1, 5 83.35(n)1
    89.54(a)1
      14 (33.77 cM)5
    165541  NM_001081177.11  NP_001074646.11 
     646525315 
    chicken
    (Gallus gallus)
    Aves KIF13B1 kinesin family member 13B 75.5(n)
    82.12(a)
      422026  XM_004935888.1  XP_004935945.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    91(a)
    79(a)
    many → 1
    many → 1
    4(40390661-40414732)
    4(40287054-40371607)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.245692 Xenopus laevis transcribed sequence with moderate similarity more 78.44(n)    48059171 
    zebrafish
    (Danio rerio)
    Actinopterygii kif13ba1 kinesin family member 13Ba 67.7(n)
    72.1(a)
      571520  XM_005169868.1  XP_005169925.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Khc-731 , 3 microtubule-based movement kinesin
    motor3
    Kinesin-731
    51(a)
    (best of 2)3
    56.21(n)1
    54.94(a)1
      367181  NM_001274071.11  NP_001261000.11 


    ENSEMBL Gene Tree for KIF13B (if available)
    TreeFam Gene Tree for KIF13B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for KIF13B gene
    KIF18A2  KIF16B2  KIF1C2  STARD92  KIF1B2  KIF192  KIF142  KIF222  
    KIF1A2  KIF13A2  KIF18B2  
    Selected SIMAP similar genes for KIF13B using alignment to 8 protein entries:     KI13B_HUMAN (see all proteins) (see all similar genes):
    KIF13A    KIF1A    KIF1C    KIF3B    KIF3A    KIF28P
    KIF5C    KIF5B    KIF23    KIF5A    A20    KIF18B
    KIF3C    KIF5B-ALK    KIFC3    R11    R12    STARD9

    Find genes that share paralogs with KIF13B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KIF13B (see all 4259)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs114187451,2
    C--27532017(+) AAAAA-/A/AA  
            
    TTCCA
    1 -- int1 trp30--------
    rs1881119251,2
    --27667392(+) CACCAC/TGACAC 1 -- us2k10--------
    rs1471524531,2
    C--28924417(+) CCAAGA/GAGAGT 1 -- int10--------
    rs1386345571,2
    --28924613(+) GCTGGA/GGAGGC 1 -- int10--------
    rs285225061,2
    C,F--28924642(+) TTCCCT/CGATCC 1 -- int16Minor allele frequency- C:0.15WA CSA NA 246
    rs1892698351,2
    --28924712(+) CACCAC/TGACAG 1 -- int10--------
    rs1473823491,2
    --28924750(+) TATGTC/TGGGGT 1 -- int10--------
    rs1811634591,2
    --28924779(+) CAAGAC/TTGGCC 1 -- int10--------
    rs38168271,2
    C,F,H--28924810(-) CCAGAC/TCATTT 1 -- ut31 ese38Minor allele frequency- T:0.01EA NA NS 2060
    rs26931,2
    C,F,O,A,H--28924858(-) GTACCG/ATATGT 1 -- ut31 ese334Minor allele frequency- A:0.36MN EA NA NS WA CSA 4794

    HapMap Linkage Disequilibrium report for KIF13B (28924795 - 29120641 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for KIF13B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2501473CNV Deletion19546169
    esv2736816CNV Deletion23290073
    nsv528871CNV Loss19592680
    esv5693CNV Gain19470904
    nsv831276CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607350    OMIM disorders: --


    Find genes that share disorders with KIF13B           About GenesLikeMe

    Genetic Association Database (GAD): KIF13B
    Human Genome Epidemiology (HuGE) Navigator: KIF13B (2 documents)

    Export disorders for KIF13B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KIF13B gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with KIF13B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytes. (PubMed id 10859302)1, 2, 3, 9 Hanada T.... Chishti A.H. (J. Biol. Chem. 2000)
    2. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (DNA Res. 1998)
    3. Transport of PIP3 by GAKIN, a kinesin-3 family protein, regulates neuronal cell polarity. (PubMed id 16864656)1, 3, 9 Horiguchi K....Chishti A.H. (J. Cell Biol. 2006)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. Par1b/MARK2 phosphorylates kinesin-like motor protein GAKIN/KIF13B to regulate axon formation. (PubMed id 20194617)1, 2 Yoshimura Y.... Miki H. (Mol. Cell. Biol. 2010)
    6. Human variation in alcohol response is influenced by variation in neuronal signaling genes. (PubMed id 20201926)1, 4 Joslyn G....White R.L. (Alcohol. Clin. Exp. Res. 2010)
    7. Direct interaction with a kinesin-related motor mediates transport of mammalian discs large tumor suppressor homologue in epithelial cells. (PubMed id 12496241)1, 9 Asaba N....Chishti A.H. (J. Biol. Chem. 2003)
    8. The effector domain of human Dlg tumor suppressor acts as a switch that relieves autoinhibition of kinesin-3 motor GAKIN/KIF13B. (PubMed id 17696365)1, 9 Yamada K.H....Chishti A.H. (Biochemistry 2007)
    9. Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. (PubMed id 23934736)1 Yu B....Boerwinkle E. (Genet. Epidemiol. 2013)
    10. Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid. (PubMed id 23319000)1 Luykx J.J....Ophoff R.A. (Mol. Psychiatry 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23303 HGNC: 14405 AceView: KIF13B Ensembl:ENSG00000197892 euGenes: HUgn23303
    ECgene: KIF13B H-InvDB: KIF13B

    (According to HUGE)
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    HUGE: KIAA0639

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KIF13B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KIF13B gene:
    Search GeneIP for patents involving KIF13B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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