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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

KIF13A Gene

protein-coding   GIFtS: 56
GCID: GC06M017759

kinesin family member 13A
 Explore 4 diseases affiliated with
KIF13A via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for KIF13A    

Aliases
for KIF13A gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Kinesin Family Member 13A1 2
BA500C11.21
Kinesin-Like Protein RBKIN2 3
RBKIN2 3
Homolog Of Mouse KIF13A Mannose-6-Phosphate Receptor Transporter2
Kinesin-Like Protein KIF13A2

External Ids:    HGNC: 145661   Entrez Gene: 639712   Ensembl: ENSG000001371777   OMIM: 6054335   UniProtKB: Q9H1H93   

Export aliases for KIF13A gene to outside databases

Previous GC identifers: GC06M017818 GC06M017868 GC06M017871 GC06M017705


Summaries
for KIF13A gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for KIF13A:
This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning
of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi
network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It
is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis,
and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript
variants. (provided by RefSeq, Aug 2011)

UniProtKB/Swiss-Prot: KI13A_HUMAN, Q9H1H9
Function: Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating
various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting
during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi
network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required
for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling
endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of
ZFYVE26, and possibly TTC19, to the midbody during cytokinesis

Gene Wiki entry for KIF13A


Genomic Views
for KIF13A gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the KIF13A gene promoter:
         Sox5   AP-2alpha isoform 3   AML1a   NRSF form 1   NRSF form 2   C/EBPalpha   Evi-1   IRF-7A   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: KIF13A promoter sequence
   Search SABiosciences Chromatin IP Primers for KIF13A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIF13A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p23   Ensembl cytogenetic band:  6p22.3   HGNC cytogenetic band: 6p23

KIF13A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIF13A gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M017759:  view genomic region     (about GC identifiers)

Start:
 17,759,414 bp from pter      End:
 17,987,854 bp from pter
Size:
 228,441 bases      Orientation:
 minus strand

Proteins
for KIF13A gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: KI13A_HUMAN, Q9H1H9 (See protein sequence)
Recommended Name: Kinesin-like protein KIF13A  
Size: 1805 amino acids; 202308 Da
Subunit: Interacts with AP2B1 (By similarity). Interacts with ZFYVE26. Interacts with AP1G1 and AP1G2
Subcellular location: Cytoplasm, cytoskeleton, centrosome. Midbody. Endosome membrane. Golgi apparatus membrane (By
similarity). Note=Recruited to the midbody during cytokinesis
Developmental stage: Expressed at very low level in most fetal tissues, but at higher levels in skeletal muscle and
lung
Sequence caution: Sequence=CAI21670.1; Type=Erroneous gene model prediction; Sequence=CAI21671.1; Type=Erroneous gene
model prediction; Sequence=CAI40947.1; Type=Erroneous gene model prediction; Sequence=CAI40948.1; Type=Erroneous gene
model prediction;
Secondary accessions: A0JP21 A0JP22 F2Z382 Q5THQ2 Q5THQ3 Q9H193 Q9H194 Q9H1H8
Alternative splicing: 5 isoforms:  Q9H1H9-1   Q9H1H9-2   Q9H1H9-3   Q9H1H9-4   Q9H1H9-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for KIF13A: NX_Q9H1H9

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H1H9

    • KIF13A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (5 alternative transcripts): 
    NP_001099036.1  NP_001099037.1  NP_001099038.1  NP_001230352.1  NP_071396.4  

    ENSEMBL proteins: 
     ENSP00000368091   ENSP00000425616   ENSP00000259711   ENSP00000368120   ENSP00000368103  
     ENSP00000454813   ENSP00000351150   ENSP00000422808   ENSP00000425453   ENSP00000368093  
    Reactome Protein details: Q9H1H9
    Human Recombinant Protein Products: 
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    Uscn Proteins for KIF13A

    Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005622intracellular ----
    GO:0005813centrosome IDA--
    GO:0005874microtubule IEA--
    GO:0005875microtubule associated complex IEA--


    KIF13A for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for KIF13A

    Protein Domains /
    Families
    for KIF13A gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    KIF13A for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR008984 SMAD_FHA_domain
     IPR022140 KIF1B
     IPR022164 Kinesin-like
     IPR001752 Kinesin_motor_dom
     IPR000253 FHA_dom

    Graphical View of Domain Structure for InterPro Entry Q9H1H9

    ProtoNet protein and cluster: Q9H1H9

    2 Blocks protein families:
    IPB000253 Forkhead-associated (FHA)
    IPB001752 Kinesin


    UniProtKB/Swiss-Prot: KI13A_HUMAN, Q9H1H9
    Similarity: Belongs to the kinesin-like protein family
    Similarity: Contains 1 FHA domain
    Similarity: Contains 1 kinesin-motor domain


    Function
    for KIF13A gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: KI13A_HUMAN, Q9H1H9
    Function: Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating
    various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting
    during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi
    network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required
    for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling
    endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of
    ZFYVE26, and possibly TTC19, to the midbody during cytokinesis

    miRNA
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    hsa-miR-429 hsa-miR-301a hsa-miR-519a hsa-miR-200b hsa-miR-130b hsa-miR-301b hsa-miR-519c-3p hsa-miR-3666
    SwitchGear 3'UTR luciferase reporter plasmid: KIF13A 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Search LifeMap BioReagents cell lines for KIF13A

    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003777microtubule motor activity ISS--
    GO:0005515protein binding IPI--
    GO:0005524ATP binding IEA--


    KIF13A for ontologies           About GeneDecksing



    Pathways & Interactions
    for KIF13A gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Chaperonin-mediated protein folding
    		Chaperonin-mediated protein folding1.00
    		Association of TriC/CCT with target proteins during biosynthesis0.60
    		Protein folding0.91
    2Reelin Pathway (Cajal-Retzius cells)
    		Reelin Pathway (Cajal-Retzius cells)1.00
    3Asparagine N-linked glycosylation
    		Metabolism of proteins0.15

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for KIF13A
        Reelin Pathway (Cajal-Retzius cells)

    4        Reactome Pathways for KIF13A
        Association of TriC/CCT with target proteins during biosynthesis
    Chaperonin-mediated protein folding
    Metabolism of proteins
    Protein folding



    KIF13A for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KIF13A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/11 Interacting proteins for KIF13A (Q9H1H92, 3 ENSP000002597114) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATF7IPQ6VMQ62, 3MINT-61908 I2D: score=3 
    AP1B1Q105673, ENSP000003501994I2D: score=2 STRING: ENSP00000350199
    GTF2H1P327803, ENSP000002659634I2D: score=1 STRING: ENSP00000265963
    PIK3R1P279863, ENSP000002743354I2D: score=1 STRING: ENSP00000274335
    PPP1CAP621363, ENSP000003260314I2D: score=1 STRING: ENSP00000326031
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000910cytokinesis IMP--
    GO:0006886intracellular protein transport IMP--
    GO:0007018microtubule-based movement ----
    GO:0007049cell cycle IEA--
    GO:0008333endosome to lysosome transport IMP19841138


    KIF13A for ontologies           About GeneDecksing



    Drugs & Compounds
    for KIF13A gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for KIF13A

    1 HMDB Compound for KIF13A    About this table
    CompoundSynonyms CAS #PubMed Ids
    Mannose 6-phosphateD-Mannose 6-phosphate (see all 10)3672-15-9--
    Search CenterWatch for drugs/clinical trials and news about KIF13A / KI13A 

    Transcripts
    for KIF13A gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for KIF13A gene (5 alternative transcripts): 
    NM_001105566.2  NM_001105567.2  NM_001105568.2  NM_001243423.1  NM_022113.5  

    Unigene Cluster for KIF13A:

    Kinesin family member 13A
    Hs.94499  [show with all ESTs]
    Unigene Representative Sequence: NM_001105568
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000378814(uc003nce.2 uc003ncf.3) ENST00000502297 ENST00000259711(uc003ncg.4 uc003nch.4 uc003nci.4)
    ENST00000378843 ENST00000378826 ENST00000562486(uc003ncj.3) ENST00000358380
    ENST00000506044 ENST00000514714 ENST00000503342 ENST00000507576 ENST00000505588
    ENST00000502704(uc003nck.3) ENST00000378816

    miRNA
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    8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate KIF13A (see all 18):
    hsa-miR-429 hsa-miR-301a hsa-miR-519a hsa-miR-200b hsa-miR-130b hsa-miR-301b hsa-miR-519c-3p hsa-miR-3666
    SwitchGear 3'UTR luciferase reporter plasmid: KIF13A 3' UTR sequence
    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AJ291578.1 AJ291579.1 AK025303.1 AK225214.1 AY014403.1 AY014404.1 BC001730.1 BC023613.2 
    BC062673.1 BC127115.1 BC127116.1 

    14 DOTS entries:

    DT.111577  DT.95313882  DT.411892  DT.100754528  DT.91667004  DT.100754530  DT.101981997  DT.106057 
    DT.101969609  DT.203423  DT.97815550  DT.121333387  DT.100018241  DT.91660011 

    24/90 AceView cDNA sequences (see all 90):

    BE675263 AA633254 BU629053 AJ291578 AI524805 BU634123 F10583 AJ291579 
    F10582 BM808168 AA927630 BM807994 F12986 N32528 AI277715 BM559010 
    BM468655 CD721878 AI741491 BM911908 BQ708867 BC001730 AY014404 NM_022113 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for KIF13A (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^
    SP1:                    -                                                                                                                                       
    SP2:                    -                                                                                                                                       
    SP3:                    -                                                                                                                                       
    SP4:                    -                                                                                                                                       
    SP5:                                                                                                                                                            

    ExUns: 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33 ^ 34 ^ 35 ^ 36 ^ 37a · 37b ^ 38 ^ 39a · 39b ^ 40
    SP1:                                                                                -                           
    SP2:                                                                                -     -                     
    SP3:        -                                                                       -     -           -         
    SP4:        -                                                                       -     -                     
    SP5:                                                                                                            


    ECgene alternative splicing isoforms for KIF13A

    Expression
    for KIF13A gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    KIF13A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTGCCGCCTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    KIF13A expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Primitive StreakPrimitive NodePrimitive Node CellsEarly Embryo
    BrainMedulla OblongataBrain
    Neural TubeMetencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See KIF13A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for KIF13A

    SOURCE GeneReport for Unigene cluster: Hs.94499

    UniProtKB/Swiss-Prot: KI13A_HUMAN, Q9H1H9
    Tissue specificity: Widely expressed, with highest levels in heart, brain and skeletal muscle

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    Orthologs
    for KIF13A gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for KIF13A gene from 5/22 species (see all 22)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves KIF13A1 kinesin family member 13A 79.44(n)
    88.99(a)    		   420832  XM_418923.2  XP_418923.2 
    lizard
    (Anolis carolinensis)    		 Reptilia KIF13A6
    		 --
    		 86(a)
    		 1 ↔ 1
    		 4(56974447-57043208)
    zebrafish
    (Danio rerio)    		 Actinopterygii kif13a1 kinesin family member 13A 69.39(n)
    76.19(a)    		   100331282  XM_002665062.1  XP_002665108.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Khc-731 , 3 microtubule-based movement kinesin motor3
    Kinesin-731    		 57(a)
    (best of 3)3
    53.75(n)1
    53.18(a)1    		   367181  NM_135357.31  NP_609201.31 
    worm
    (Caenorhabditis elegans)    		 Secernentea klp-41 , 3 kinesin-related protein3
    Protein KLP-41    		 45(a)
    (best of 2)3
    54.44(n)1
    51.72(a)1    		   X(3207003-3213963)3
    1806081  NM_076145.21  NP_508546.21 


    ENSEMBL Gene Tree for KIF13A (if available)
    TreeFam Gene Tree for KIF13A (if available) 

    Paralogs
    for KIF13A gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for KIF13A gene
    KIF18A2  KIF1C2  KIF16B2  KIF1B2  KIF192  KIF222  KIF142  KIF13B2  
    KIF1A2  KIF122  KIF18B2  
    14 SIMAP similar genes for KIF13A using alignment to 6 protein entries:     KI13A_HUMAN (see all proteins):
    KIF13B    KIF1A    KIF6    KIF3A    KIF1C    KIF5C
    KIFC3    KIF23    KIF5B    KIF5A    KIF9    KIF21A
    KIF2C    KIF27

    KIF13A for paralogs           About GeneDecksing



    Genomic Variants
    for KIF13A gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3959 NCBI SNPs in KIF13A are shown (see all 3959)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs795238851,2
    		F,--17704185(+) CCCCCC/TTCCAC 1 -- ds50011Minor allele frequency- T:0.05NA 120
    rs764932671,2
    		F,--17705095(+) CTTCAT/CAGCTC 1 -- ut311Minor allele frequency- C:0.03WA 118
    rs122125011,2
    		C,F,H,--17705494(+) AGGGAA/GTTATG 1 -- ut318Minor allele frequency- G:0.15EA NS WA NA 634
    rs783075681,2
    		F,--17705669(+) CATGTA/GTAAGA 1 -- ut311Minor allele frequency- G:0.05NA 120
    rs69065161,2
    		H--17705679(+) AGATCG/CCCCAA 1 -- ut314Minor allele frequency- C:0.00NS EA 412
    rs1117962481,2
    		C,F,--17706927(+) CAGTAG/AAGACA 1 -- int12Minor allele frequency- A:0.50WA CSA 4
    rs94650701,2
    		--17706954(+) gtcagC/Gctggt 1 -- int10--------
    rs121989741,2
    		--17706985(+) tgatcC/Tgcccg 1 -- int10--------
    rs1135469651,2
    		C,--17707408(+) GAATTC/TGAATT 1 -- int11Minor allele frequency- T:0.50NA 2
    rs764553581,2
    		C,--17707475(+) GTCCAG/TACTGG 1 -- int11Minor allele frequency- T:0.50WA 2

    HapMap Linkage Disequilibrium report for KIF13A (17759414 - 17987854 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for KIF13A
         1 CNV: 4486
         1 Indel: 69341

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    Disorders / Diseases
    for KIF13A gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    KIF13A for disorders           About GeneDecksing

    OMIM gene information: 605433    OMIM disorders: --

    4 diseases for KIF13A:    About MalaCards
    retinoblastoma    schizophrenia    malaria    neuronitis

    Human Genome Epidemiology (HuGE) Navigator: KIF13A (3 documents)

    Export disorders for KIF13A gene to outside databases

    Publications
    for KIF13A gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for KIF13A gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with KIF13A)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex. (PubMed id 11106728)1, 3, 9 Nakagawa T....Hirokawa N. (2000)
    2. Genomic amplification in retinoblastoma narrowed to 0.6 megabase on chromosome 6p containing a kinesin-like gene, RBKIN. (PubMed id 11861365)1, 2, 9 Chen D.... Gallie B.L. (2002)
    3. PtdIns(3)P controls cytokinesis through KIF13A-mediat ed recruitment of FYVE-CENT to the midbody. (PubMed id 20208530)1, 2 Sagona A.P....Stenmark H. (2010)
    4. AP-1 and KIF13A coordinate endosomal sorting and posi tioning during melanosome biogenesis. (PubMed id 19841138)1, 2 Delevoye C....Raposo G. (2009)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    6. Identification of the human KIF13A gene homologous to Drosophila kinesin-73 and candidate for schizophrenia. (PubMed id 11374900)1, 2 Jamain S.... Bourgeron T. (2001)
    7. A genome-wide search for loci interacting with known p rostate cancer risk-associated genetic variants. (PubMed id 22219177)1 Tao S....Sun J. (2012)
    8. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    9. The kinesin-13 MCAK has an unconventional ATPase cycl e adapted for microtubule depolymerization. (PubMed id 21873978)1 Friel C.T. and Howard J. (2011)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    External Searches for KIF13A gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing KIF13A gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 63971 HGNC: 14566 AceView: KIF13A Ensembl:ENSG00000137177 euGenes: HUgn63971
    ECgene: KIF13A H-InvDB: KIF13A

    Other Databases showing KIF13A gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing KIF13A gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for KIF13A Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for KIF13A gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for KIF13A gene:
    Search GeneIP for patents involving KIF13A

    GeneCards and IP:
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