KIDINS220 Gene
protein-coding GIFtS : 57
GCID: GC02 M008865
kinase D-interacting substrate, 220kDa
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Aliasesfor KIDINS220 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Kinase D-Interacting Substrate, 220kDa 1 2 ARMS1 2 3 Ankyrin Repeat-Rich Membrane-Spanning Protein2 3 Ankyrin Repeat-Rich Membrane Spanning2 Kinase D-Interacting Substrate Of 220 KDa2 KIAA12503
Export aliases for KIDINS220 gene to outside databases Previous GC identifers: GC02U990270 GC02M008920 GC02M008890 GC02M008819 GC02M008786 GC02M008715
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Summariesfor KIDINS220 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: KDIS_HUMAN, Q9ULH0 Function : Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism.Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway Gene Wiki entry for KIDINS220
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Genomic Viewsfor KIDINS220 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000002.11 NC_018913.1 NT_005334.16 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the KIDINS220 gene promoter: TBP LHX3b/Lhx3b AML1a GATA-3 TFIID LHX3a/Lhx3a GATA-1 GATA-2 Other transcription factors Search SABiosciences Chromatin IP Primers for KIDINS220 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIDINS220
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 2p24 Ensembl cytogenetic band: 2p25.1 HGNC cytogenetic band: 2p24 KIDINS220 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 2 GeneLoc Exon Structure
GeneLoc location for GC02M008865: view genomic region
(about GC identifiers )
Start:
8,865,408 bp from pter
End:
8,977,760 bp from pter
Size:
112,353 bases
Orientation:
minus strand
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Proteinsfor KIDINS220 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: KDIS_HUMAN, Q9ULH0 (See
protein sequence )Recommended Name: Kinase D-interacting substrate of 220 kDa Size : 1771 amino acids; 196542 Da
Subunit : Interacts with NTRK1, NTRK2, NTRK3, ERKL and NGFR. Can form a ternary complex with NGFR and NTRK1 and thiscomplex is affected by the expression levels of KIDINS220/ARMS. An increase in KIDINS220/ARMS expression leads to a decreased association of NGFR and NTRK1. Interacts with SNTA1 and SNTB2 and binds to their PDZ domains. Interacts with EPHA4 and PRKD1 (By similarity)
Subcellular location : Membrane; Multi-pass membrane protein (Potential)
Sequence caution : Sequence=BAA86564.2; Type=Erroneous initiation; Sequence=BAB14728.1; Type=Erroneous initiation;
Secondary accessions : A1L4N4 Q4VC08 Q6MZU2 Q9H889 Q9H9E4 Q9NT37 Q9UF42Alternative splicing : 5 isoforms : Q9ULH0-1 Q9ULH0-2 Q9ULH0-3 Q9ULH0-4 Q9ULH0-5 Explore the universe of human proteins at neXtProt for KIDINS220: NX_Q9ULH0 Post-translational modifications:
Tyrosine phosphorylated by NTRK1, NTRK2, EPHB2 and EPHA4. Phosphorylation at Ser-918 is induced by phorbol ester treatment. Phosphorylation by NTRK2 is induced by brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5. Phosphorylation by NTRK1 is induced by nerve growth factor (NGF) (By similarity)1
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9ULH0 KIDINS220 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_065789.1 ENSEMBL proteins: ENSP00000420364 ENSP00000256707 ENSP00000418974 ENSP00000417390 ENSP00000419964 ENSP00000419232 ENSP00000319947 ENSP00000411849 ENSP00000414923 Reactome Protein details: Q9ULH0 Human Recombinant Protein Products: Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view) : About this table
KIDINS220 for ontologies About GeneDecksing KIDINS220 Antibody Products: Assay Products for KIDINS220:
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Protein
Domains / Familiesfor KIDINS220 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
KIDINS220 for domains About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q9ULH0 ProtoNet protein and cluster: Q9ULH0
1 Blocks protein family : IPB002110 Ankyrin repeat signature UniProtKB/Swiss-Prot: KDIS_HUMAN, Q9ULH0 Domain : The transmembrane domain mediates interaction with NTRK1 (By similarity)Similarity : Contains 12 ANK repeatsSimilarity : Contains 1 KAP NTPase domain
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Functionfor KIDINS220 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: KDIS_HUMAN, Q9ULH0 Function : Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism.Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for KIDINS220 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for KIDINS220OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: KIDINS220 (NM_020738 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIDINS220 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat KIDINS220
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIDINS220
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0016301 kinase activity
-- --
KIDINS220 for ontologies About GeneDecksing 1 GenomeRNAi human phenotype for KIDINS220 :Animal Models: Mouse knock-out Kidins220 tm1.1Mvc for KIDINS220 2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Kidins220) :
KIDINS220 for phenotypes About GeneDecksing
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Pathways & Interactionsfor KIDINS220 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways   About this table See pathways by source Super-pathway contained gene-specific pathways 1 ARMS-mediated activation 2 Signaling by FGFR 3 Signalling to RAS 4 Signaling by GPCR 5 Development HGF signaling pathway
Pathway sources See GeneCards unified pathways Show all pathways 5/6
Reactome Pathways for KIDINS220 (see all 6 )1
Kegg Pathway (Kegg details for KIDINS220) :
KIDINS220 for pathways About GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for KIDINS220 STRING Interaction
Network Preview (showing 5 interactants - click image to see 12)5/16 Interacting proteins for KIDINS220 (Q9ULH0 2 , 3 ENSP00000256707 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 16 )About this table Gene Ontology (GO): 4 biological process terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0000186 activation of MAPKK activity
TAS -- GO:0001701 in utero embryonic development
IEA -- GO:0048011 nerve growth factor receptor signaling pathway
TAS -- GO:0048813 dendrite morphogenesis
IEA --
KIDINS220 for ontologies About GeneDecksing
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Drugs & Compoundsfor KIDINS220 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for KIDINS220 Search CenterWatch for drugs/clinical trials and news about KIDINS220 / KDIS
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Transcriptsfor KIDINS220 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for KIDINS220 gene: NM_020738.2 Unigene Cluster for KIDINS220:
Kinase D-interacting substrate, 220kDa Hs.9873 [show with all ESTs ] Unigene Representative Sequence: NM_020738 14 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000436566 ENST00000496383 ENST00000256707 (uc002qzc.2 ) ENST00000473731 ENST00000488729 ENST00000489024 ENST00000471685 ENST00000459813 (uc002qze.3 )ENST00000319688 ENST00000474782 ENST00000471275 ENST00000496725 ENST00000427284 (uc002qzb.2 )ENST00000418530 (uc010yiv.1 uc002qzd.2 uc010yiw.1 ) Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for KIDINS220 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for KIDINS220OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: KIDINS220 (NM_020738 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIDINS220 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat KIDINS220
Additional cDNA sequence: AB033076.2 AB621829.1 AK022873.1 AK023926.1 AK025528.1 AK057125.1 AK294464.1 AK294832.1 AK295358.1 AK296459.1 AL133620.1 AL137553.1 BC039409.1 BC094714.1 BC130610.1 BX538189.1 BX640878.1
17 DOTS entries : DT.318126 DT.40294526
DT.92036765 DT.100788484 DT.100788482 DT.120959596 DT.92431823 DT.101968211 DT.120758684 DT.120959630 DT.120959616 DT.120959628 DT.86838969 DT.91657622 DT.91741022 DT.95257091 DT.120959570 24/273 AceView cDNA sequences (see all 273 ):
BM713323 AW083704 AI421078 BX440076 BM665957 BU431395 BX538189 AB033076 BM985061 CA448925 AW139615 Z41158 AU127977 BF594244 CD678859 AA350027 BQ960614 AA081690 AI478209 AL712289 AA807130 BU734021 AA648418 AI335860 GeneLoc Exon Structure 5/15 Alternative Splicing Database (ASD) splice patterns (SP) for KIDINS220 (see all 15 ) About this scheme ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ SP1 :       -   -             -         -       -                   SP2 :       -   -             -         -       -                   SP3 :                                                     SP4 :                                                     SP5 :       -                                              
ExUns: 20a · 20b ^ 21a · 21b ^ 22 ^ 23a · 23b ^ 24 ^ 25a · 25b ^ 26 ^ 27a · 27b · 27c ^ 28 ^ 29a · 29b ^ 30a · 30b ^ 31a · 31b ^ 32a · 32b · 32c ^ 33a · 33b · SP1 :                                                     SP2 :                                                     SP3 :                             -   -   -   -   -   -               SP4 :                             -       -   -   -               SP5 :                                                    
ExUns: 33c ^ 34 SP1 :     SP2 :     SP3 :     SP4 :     SP5 :    
ECgene alternative splicing isoforms for KIDINS220
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Expression for KIDINS220 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section KIDINS220 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: --
About this image KIDINS220 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See KIDINS220 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for KIDINS220 SOURCE GeneReport for Unigene cluster: Hs.9873 UniProtKB/Swiss-Prot: KDIS_HUMAN, Q9ULH0 Tissue specificity : Abundant in developing and adult neural tissues as well as neuroendocrine cells and dendriticcells. Overexpressed in melanoma and melanoma cell lines SABiosciences Custom PCR Arrays for KIDINS220 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for KIDINS220Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat KIDINS220 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat KIDINS220 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat KIDINS220 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIDINS220
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Orthologsfor KIDINS220 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the last universal common ancestor (LUCA).
Orthologs for KIDINS220 gene from 8/23 species (see all 23 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
KIDINS2201
kinase D-interacting substrate, 220kDa
79.71(n) 87.22(a)
 
421924 XM_419939.2 XP_419939.2
lizard (Anolis carolinensis)
Reptilia
KIDINS2206 --
--
85(a) 20(a)
1 ↔ 1possible ortholog
1(148899225-148951304) 4(101979115-101980806)
African clawed frog (Xenopus laevis)
Amphibia
Xl.140362
Xenopus laevis transcribed sequence with weak similarity more
76.84(n)
 
CA985593.1
zebrafish (Danio rerio)
Actinopterygii
wufj35h032
wufj35h03
74.57(n)
 
335881 BC061450.1
fruit fly (Drosophila melanogaster)
Insecta
CG426721
CG42672
49.14(n) 43.09(a)
 
37433 NM_166442.3 NP_726060.3
worm (Caenorhabditis elegans)
Secernentea
F36H1.23 tag-1441
ankyrin like3 Protein TAG-1441
35(a) 3 49.98(n) 1 40.1(a) 1
 
IV(11039059-11047194)3 178000 1 NM_001083218.3 1 NP_001076687.2 1
rice (Oryza sativa)
Liliopsida
--
ankyrin repeat domain-containing protein 50, putat...
16(a)
possible ortholog
3(25568429-25570099)
E. coli (Escherichia coli)
Gamma proteobacteria
yahD6
ankyrin repeat protein
19(a)
possible ortholog
Chromosome(334504-335109)
ENSEMBL Gene Tree for KIDINS220 (if available)TreeFam Gene Tree for KIDINS220 (if available)
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Paralogsfor KIDINS220 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for KIDINS220 gene ANKRD29 2 FEM1B 2 FEM1A 2 FEM1C 2 17 SIMAP similar genes for KIDINS220 using alignment to 6 protein entries: KDIS_HUMAN (see all proteins ):DKFZp686H14204 ANKRD12 ANKRD44 ANKRD29 ANK2 ANKDD1A FANK1 CDKN2C TANC2 TNKS ASB3 DKFZp761E1322 MTPN PSMD10 ANKRD10 CDKN2A INVS
KIDINS220 for paralogs About GeneDecksing
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Genomic Variantsfor KIDINS220 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 2 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for KIDINS220 (8865408 - 8977760 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for KIDINS220 1 CNV : 97761
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing KIDINS220
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Disorders
/ Diseasesfor KIDINS220 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
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KIDINS220 for disorders About GeneDecksing 3 diseases for KIDINS220 : About MalaCards substance abuse melanoma neuronitis Export disorders for KIDINS220 gene to outside databases
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Publicationsfor KIDINS220 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for KIDINS220 gene, integrated from 9 sources (see all 35 ): (articles sorted by number of sources associating them with KIDINS220) Utopia : connect your pdf to the dynamic world of online information
Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462) 1 , 2 , 3 Nagase T.... Ohara O. (1999) ARMS depletion facilitates UV irradiation induced apoptotic cell death in melanoma. (PubMed id 18089783) 1 , 2 Liao Y.-H.... Huang P.-H. (2007) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Identification and cloning of Kidins220, a novel neuronal substrate of protein kinase D. (PubMed id 10998417) 1 , 3 Iglesias T....Schiavo G. (2000) Kidins220/ARMS interacts with Pdzrn3, a protein contai ning multiple binding domains. (PubMed id 22609016) 1 Andreazzoli M....Dente L. (2012) Kidins220/ARMS as a functional mediator of multiple re ceptor signalling pathways. (PubMed id 22562556) 1 Neubrand V.E....Schiavo G. (2012) The neuronal protein Kidins220/ARMS associates with I CAM-3 and other uropod components and regulates T-cell motility. (PubMed id 21381019) 1 Jean-Mairet R.M....Iglesias T. (2011) Initial characterization of the human central proteome. (PubMed id 21269460) 2 Burkard T.R.... Colinge J. (2011) A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473) 1 Wagner S.A....Choudhary C. (2011) Upregulated ankyrin repeat-rich membrane spanning pro tein contributes to tumour progression in cutaneous melanoma. (PubMed id 21343931) 1 Liao Y.H....Huang P.H. (2011)
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External Searches for KIDINS220 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing KIDINS220 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
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Other Databases showing KIDINS220 gene
(According to HUGE )
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Specialized Databases showing KIDINS220 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for KIDINS220 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for KIDINS220 gene: Search GeneIP for patents involving KIDINS220 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor KIDINS220 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
OriGene Antibodies for KIDINS220 OriGene shRNA RFP for KIDINS220 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for KIDINS220 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for KIDINS220 Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for KIDINS220 OriGene 3'-UTR Clone for KIDINS220 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for KIDINS220 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for KIDINS220 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for KIDINS220 OriGene Custom Protein Services for KIDINS220 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIDINS220 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing KIDINS220 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIDINS220 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat KIDINS220 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat KIDINS220 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat KIDINS220
KIDINS220 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIDINS220
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat KIDINS220
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