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Aliases for KIAA2026 Gene

Aliases for KIAA2026 Gene

  • KIAA2026 2 3

External Ids for KIAA2026 Gene

Previous GeneCards Identifiers for KIAA2026 Gene

  • GC09M005900
  • GC09M005909
  • GC09M005874
  • GC09M005919

Summaries for KIAA2026 Gene

GeneCards Summary for KIAA2026 Gene

KIAA2026 (KIAA2026) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA2026 Gene

Genomics for KIAA2026 Gene

Regulatory Elements for KIAA2026 Gene

Enhancers for KIAA2026 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F006679 0.9 FANTOM5 Ensembl ENCODE 10.6 -673.9 -673918 5.2 HDGF PKNOX1 ARNT MLX CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 LOC105375968 AK4P4 KIAA2026 SNRPEP2 ENSG00000225489 GLDC KDM4C UHRF2 GC09P006678
GH09F006024 0.7 Ensembl ENCODE 5.2 -15.7 -15722 0.4 CTCF ZBTB11 DPF2 RAD21 ZNF644 CTBP1 GATA3 SCRT2 IKZF1 CUX1 KIAA2026 RANBP6 ENSG00000228739
GH09F005623 1.2 FANTOM5 ENCODE 2.3 +381.2 381240 7.1 HDGF PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 ZNF766 ZNF143 ZNF207 RIC1 PLGRKT KIAA2026 CD274 RANBP6 GC09P005625 LOC105375967
GH09F005556 1.1 FANTOM5 Ensembl ENCODE 1.5 +450.1 450079 4.4 MXI1 PKNOX1 MAX MAFG RELA ZNF316 MAFF POLR2A EED ZNF512 PDCD1LG2 CD274 PLGRKT RCL1 RIC1 KIAA2026 GC09M005559 GC09P005527
GH09F006006 1 ENCODE 0.8 +0.5 537 3.4 HDGF PKNOX1 ARID4B SIN3A YY1 ZNF207 DEK ZNF263 SP3 SP5 ERMP1 MIR4665 KIAA2026
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around KIAA2026 on UCSC Golden Path with GeneCards custom track

Promoters for KIAA2026 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001299654 879 3201 HDGF PKNOX1 ARID4B SIN3A YY1 ZNF207 DEK ZNF263 SP3 SP5

Genomic Location for KIAA2026 Gene

Chromosome:
9
Start:
5,859,595 bp from pter
End:
6,008,479 bp from pter
Size:
148,885 bases
Orientation:
Minus strand

Genomic View for KIAA2026 Gene

Genes around KIAA2026 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA2026 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA2026 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA2026 Gene

Proteins for KIAA2026 Gene

  • Protein details for KIAA2026 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5HYC2-K2026_HUMAN
    Recommended name:
    Uncharacterized protein KIAA2026
    Protein Accession:
    Q5HYC2
    Secondary Accessions:
    • A8MTP2
    • B9EGW7
    • Q4VXA2
    • Q8IVE5

    Protein attributes for KIAA2026 Gene

    Size:
    2103 amino acids
    Molecular mass:
    228087 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI36847.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAI45993.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAI95313.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA2026 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA2026 Gene

Post-translational modifications for KIAA2026 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for KIAA2026 Gene

Domains & Families for KIAA2026 Gene

Protein Domains for KIAA2026 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA2026: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for KIAA2026 Gene

Function for KIAA2026 Gene

genes like me logo Genes that share phenotypes with KIAA2026: view

Animal Model Products

miRNA for KIAA2026 Gene

miRTarBase miRNAs that target KIAA2026

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA2026 Gene

Localization for KIAA2026 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA2026 Gene COMPARTMENTS Subcellular localization image for KIAA2026 gene
Compartment Confidence
cytosol 3
nucleus 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA2026 Gene

Pathways & Interactions for KIAA2026 Gene

SuperPathways for KIAA2026 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KIAA2026 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA2026 Gene

Transcripts for KIAA2026 Gene

Unigene Clusters for KIAA2026 Gene

KIAA2026:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA2026 Gene

No ASD Table

Relevant External Links for KIAA2026 Gene

GeneLoc Exon Structure for
KIAA2026
ECgene alternative splicing isoforms for
KIAA2026

Expression for KIAA2026 Gene

mRNA expression in normal human tissues for KIAA2026 Gene

Protein differential expression in normal tissues from HIPED for KIAA2026 Gene

This gene is overexpressed in Esophagus (27.1), Plasma (12.1), Kidney (6.7), and Placenta (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for KIAA2026 Gene



NURSA nuclear receptor signaling pathways regulating expression of KIAA2026 Gene:

KIAA2026

SOURCE GeneReport for Unigene cluster for KIAA2026 Gene:

Hs.535060
genes like me logo Genes that share expression patterns with KIAA2026: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for KIAA2026 Gene

Orthologs for KIAA2026 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA2026 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA2026 34 35
  • 99.27 (n)
dog
(Canis familiaris)
Mammalia KIAA2026 34 35
  • 90.81 (n)
cow
(Bos Taurus)
Mammalia KIAA2026 34 35
  • 90.55 (n)
mouse
(Mus musculus)
Mammalia 9930021J03Rik 34 16 35
  • 86.05 (n)
rat
(Rattus norvegicus)
Mammalia RGD1311595 34
  • 84.76 (n)
oppossum
(Monodelphis domestica)
Mammalia KIAA2026 35
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA2026 35
  • 53 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA2026 34 35
  • 69.7 (n)
lizard
(Anolis carolinensis)
Reptilia KIAA2026 35
  • 55 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa2026 34
  • 58.99 (n)
Str.20397 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.18719 34
zebrafish
(Danio rerio)
Actinopterygii KIAA2026 (2 of 2) 35
  • 42 (a)
OneToMany
CABZ01088061.1 35
  • 17 (a)
OneToMany
Species where no ortholog for KIAA2026 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA2026 Gene

ENSEMBL:
Gene Tree for KIAA2026 (if available)
TreeFam:
Gene Tree for KIAA2026 (if available)

Paralogs for KIAA2026 Gene

No data available for Paralogs for KIAA2026 Gene

Variants for KIAA2026 Gene

Sequence variations from dbSNP and Humsavar for KIAA2026 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs10115023 -- 5,872,531(+) TGTCT(A/G)CCTAG intron-variant
rs10115717 -- 5,872,704(+) CATTA(C/T)CAGGC intron-variant
rs10116214 -- 6,003,630(+) AAATA(C/T)GTTAC intron-variant
rs10117416 -- 5,999,953(+) GTATG(C/T)TGTCT intron-variant
rs10121480 -- 5,934,351(+) TATTA(C/T)GCTTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for KIAA2026 Gene

Variant ID Type Subtype PubMed ID
nsv1015450 CNV loss 25217958
nsv1029665 CNV gain 25217958
nsv613204 CNV loss 21841781

Variation tolerance for KIAA2026 Gene

Gene Damage Index Score: 4.83; 67.15% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KIAA2026 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA2026

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA2026 Gene

Disorders for KIAA2026 Gene

Relevant External Links for KIAA2026

Genetic Association Database (GAD)
KIAA2026
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA2026

No disorders were found for KIAA2026 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA2026 Gene

Publications for KIAA2026 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
  2. The UbL protein UBTD1 stably interacts with the UBE2D family of E2 ubiquitin conjugating enzymes. (PMID: 24211586) Uhler J.P. … Gustafsson C.M. (Biochem. Biophys. Res. Commun. 2014) 3 64
  3. A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. (PMID: 24104479) Vizeacoumar F.J. … Moffat J. (Mol. Syst. Biol. 2013) 3 64
  4. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S. … Ideker T. (Nat. Methods 2010) 3 64
  5. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64

Products for KIAA2026 Gene

Sources for KIAA2026 Gene

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