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KIAA2026 Gene

protein-coding   GIFtS: 43
GCID: GC09M005882          (predicted)

KIAA2026

  Search for KIAA2026
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
KIAA20261 2
Putative Uncharacterized Protein ENSP000003828132
Uncharacterized Protein KIAA20262

External Ids:    HGNC: 233781   Entrez Gene: 1583582   Ensembl: ENSG000001833547   UniProtKB: Q5HYC23   

Export aliases for KIAA2026 gene to outside databases

Previous GC identifers: GC09M005900 GC09M005909 GC09M005874 GC09M005919


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for KIAA2026 Gene:
KIAA2026 (KIAA2026) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NT_008413.19  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the KIAA2026 gene promoter:
         AhR   Pax-5   p300   FOXL1   Arnt   C/EBPalpha   CHOP-10   MZF-1   TFIID   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for KIAA2026

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat KIAA2026


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p24.1   Ensembl cytogenetic band:  9p24.1   HGNC cytogenetic band: 9p24.1

KIAA2026 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
KIAA2026 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M005882:  view genomic region     (about GC identifiers)

Start:
5,881,596 bp from pter      End:
6,008,003 bp from pter
Size:
126,408 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: K2026_HUMAN, Q5HYC2 (See protein sequence)
Recommended Name: Uncharacterized protein KIAA2026  
Size: 2103 amino acids; 228087 Da
Sequence caution: Sequence=AAI36847.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAI45993.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAI95313.1;
Type=Erroneous gene model prediction;
Secondary accessions: A8MTP2 B9EGW7 Q4VXA2 Q8IVE5
Alternative splicing: 2 isoforms:  Q5HYC2-1   Q5HYC2-2   

Explore the universe of human proteins at neXtProt for KIAA2026: NX_Q5HYC2

Explore proteomics data for KIAA2026 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See KIAA2026 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001017969.2  
    ENSEMBL proteins: 
     ENSP00000438370   ENSP00000382815   ENSP00000370870   ENSP00000444949   ENSP00000444993  

    KIAA2026 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for KIAA2026 

    KIAA2026 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Abcam antibodies for KIAA2026
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    Search LSBio for Antibodies for KIAA2026

    KIAA2026 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for KIAA2026 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR001487 Bromodomain

    Graphical View of Domain Structure for InterPro Entry Q5HYC2

    ProtoNet protein and cluster: Q5HYC2


    Find genes that share domains with KIAA2026           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with KIAA2026           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for KIAA2026
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for KIAA2026
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    miRNA
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    miRTarBase miRNAs that target KIAA2026:
    hsa-let-7a-5p (MIRT052428)

    Block miRNA regulation of human, mouse, rat KIAA2026 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KIAA2026 (see all 24):
    hsa-miR-411* hsa-miR-323-3p hsa-miR-30c hsa-miR-217 hsa-miR-379* hsa-miR-1288 hsa-miR-30d hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidKIAA2026 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for KIAA2026
    Predesigned siRNA for gene silencing in human, mouse, rat KIAA2026

    Gene Editing
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    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KIAA2026 (NM_001017969)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KIAA2026
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA2026

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA2026


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for KIAA2026
    Interactions:

        Search GeneGlobe Interaction Network for KIAA2026

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for KIAA2026 (Q5HYC22, 3 ENSP000003828154) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN1P542532, 3, ENSP000002447694MINT-2878930 I2D: score=3 STRING: ENSP00000244769
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    CREB1P162203, ENSP000003876994I2D: score=2 STRING: ENSP00000387699
    CDC42P609533, ENSP000003144584I2D: score=2 STRING: ENSP00000314458
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for KIAA2026 (K2026)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for KIAA2026 gene: 
    NM_001017969.2  

    Unigene Cluster for KIAA2026:

    KIAA2026
    Hs.535060  [show with all ESTs]
    Unigene Representative Sequence: NM_001017969
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000436015 ENST00000443149 ENST00000399933(uc010mht.3 uc003zjq.4)
    ENST00000381461 ENST00000540714 ENST00000513355
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat KIAA2026 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate KIAA2026 (see all 24):
    hsa-miR-411* hsa-miR-323-3p hsa-miR-30c hsa-miR-217 hsa-miR-379* hsa-miR-1288 hsa-miR-30d hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidKIAA2026 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for KIAA2026
    Predesigned siRNA for gene silencing in human, mouse, rat KIAA2026
    Clone
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    OriGene clones in human, mouse for KIAA2026 (see all 5)
    OriGene ORF clones in mouse, rat for KIAA2026
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: KIAA2026 (NM_001017969)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for KIAA2026
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA2026
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for KIAA2026
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat KIAA2026
      QuantiTect SYBR Green Assays in human, mouse, rat KIAA2026
      QuantiFast Probe-based Assays in human, mouse, rat KIAA2026

    Additional mRNA sequence: 

    AB095946.1 AL833370.1 BC128087.1 BC136846.1 BX648372.1 

    6 DOTS entries:

    DT.40125629  DT.112137  DT.40280944  DT.121145302  DT.75145857  DT.91801743 

    Selected AceView cDNA sequences (see all 81):

    BX648372 AA731176 AW959408 BG028655 AB095946 AA428531 AW450313 AL833370 
    AW467489 AI290134 BM661626 BG109896 AI659345 BM992657 BX417704 BU627587 
    AA779658 AA830050 BF034160 AA098864 BQ438107 AI887465 AI802474 R02828 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    KIAA2026 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAATAAACTG
    KIAA2026 Expression
    About this image

    KIAA2026 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    KIAA2026 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.535060
        Custom PCR Arrays for KIAA2026
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for KIAA2026
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat KIAA2026
    QuantiTect SYBR Green Assays in human, mouse, rat KIAA2026
    QuantiFast Probe-based Assays in human, mouse, rat KIAA2026
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA2026

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for KIAA2026 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia 9930021J03Rik1 , 5 RIKEN cDNA 9930021J03 gene1, 5 86.05(n)1
    80.27(a)1
      19 (24.30 cM)5
    2406131  NM_172836.31  NP_766424.21 
     297144025 
    chicken
    (Gallus gallus)
    Aves KIAA20261 KIAA2026 69.7(n)
    61.7(a)
      427227  XM_424814.4  XP_424814.4 
    lizard
    (Anolis carolinensis)
    Reptilia KIAA20266
    KIAA2026
    55(a)
    1 ↔ 1
    2(52523327-52573937)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.187192 Xenopus laevis transcribed sequences 74.28(n)    CA985257.1 
    zebrafish
    (Danio rerio)
    Actinopterygii KIAA2026 (2 of 2)6
    CABZ01088061.16
    Uncharacterized protein
    42(a)
    17(a)
    many → 1
    many → 1
    21(784812-796376) ENSDARG00000090250
    21(1293235-1298442) ENSDARG00000086023


    ENSEMBL Gene Tree for KIAA2026 (if available)
    TreeFam Gene Tree for KIAA2026 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for KIAA2026 (see all 2076)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs78740321,2
    C,F,A--5918513(+) GAGTTC/GAAGAC 1 -- ds50014Minor allele frequency- G:0.10WA NA 242
    rs1172197231,2
    F--5918585(+) ATGCCC/TGTAGT 1 -- ds50011Minor allele frequency- T:0.01EA 120
    rs713261971,2
    C--5918816(-) TTTTT-/TGACTC 1 -- ds50011Minor allele frequency- T:0.00NA 2
    rs764215321,2
    F--5918853(+) CACAAG/AATTTA 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1450808031,2
    --5918873(+) AGTATC/TTGTAA 1 -- ds50010--------
    rs1509630961,2
    C--5918925(+) CCCACA/CCTTAA 1 -- ds50010--------
    rs1822651301,2
    --5918945(+) GTAAAA/GGACTG 1 -- ds50010--------
    rs1854963701,2
    C--5919250(+) ATGTAG/TTTTTT 1 -- ut310--------
    rs1408111811,2
    C--5919308(+) TATCAC/TAGATA 1 -- ut310--------
    rs726973951,2
    --5919350(+) TGTCAA/GTGTAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for KIAA2026 (5881596 - 6008003 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for KIAA2026:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv892156CNV Gain21882294
    nsv892155CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing KIAA2026
    DNA2.0 Custom Variant and Variant Library Synthesis for KIAA2026

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with KIAA2026           About GenesLikeMe

    Genetic Association Database (GAD): KIAA2026

    Export disorders for KIAA2026 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for KIAA2026 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with KIAA2026)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    2. The UbL protein UBTD1 stably interacts with the UBE2D family of E2 ubiquitin conjugating enzymes. (PubMed id 24211586)1 Uhler J.P....Gustafsson C.M. (Biochem. Biophys. Res. Commun. 2014)
    3. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    4. Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (amp 2011)
    5. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (Nat. Methods 2010)
    6. Framingham Heart Study genome-wide association: results for pulmonary function measures. (PubMed id 17903307)4 Wilk J.B....O'Connor G.T. (BMC Med. Genet. 2007)
    7. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    8. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (Cell 2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 158358 HGNC: 23378 AceView: KIAA2026 Ensembl:ENSG00000183354 euGenes: HUgn158358
    ECgene: KIAA2026 H-InvDB: KIAA2026

    (According to HUGE)
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    HUGE: KIAA2026

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for KIAA2026 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for KIAA2026 gene:
    Search GeneIP for patents involving KIAA2026

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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