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Aliases for KIAA1958 Gene

Aliases for KIAA1958 Gene

  • KIAA1958 2 3

External Ids for KIAA1958 Gene

Previous GeneCards Identifiers for KIAA1958 Gene

  • GC09P106134
  • GC09P106981
  • GC09P108706
  • GC09P110629
  • GC09P112328
  • GC09P114288
  • GC09P115249
  • GC09P084933

Summaries for KIAA1958 Gene

GeneCards Summary for KIAA1958 Gene

KIAA1958 (KIAA1958) is a Protein Coding gene.

Additional gene information for KIAA1958 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1958 Gene

Genomics for KIAA1958 Gene

Regulatory Elements for KIAA1958 Gene

Enhancers for KIAA1958 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09H112793 1 Ensembl ENCODE 11.2 +306.5 306499 0 CTCF SAP130 ARID4B MAX RAD21 GATA3 CTBP1 SMC3 ZNF143 PRDM10 ENSG00000226609 SNX30 INIP KIAA1958 C9orf147 PIR49803
GH09H112447 0.8 Ensembl ENCODE 12.1 -39.2 -39247 0 PKNOX1 ZNF316 FOXK2 NFE2 DPF2 ZEB2 EMSY KIAA1958 C9orf147 HSDL2 INIP PIR60820
GH09H111937 1.6 FANTOM5 Ensembl ENCODE dbSUPER 5.3 -548.6 -548557 2 HDGF PKNOX1 RB1 BMI1 BATF EGR1 ZNF143 ATF7 ETV6 RUNX3 RNU6-710P RNU6-1013P GNG10 KIAA1958 C9orf84 PTBP3 SUSD1 DNAJC25 HSDL2 MIR4668
GH09H112788 0.7 Ensembl ENCODE 11.2 +302.9 302855 1 IKZF1 USF2 ENSG00000226609 SNX30 INIP C9orf147 KIAA1958 SLC46A2 PIR49803
GH09H112747 1.2 FANTOM5 ENCODE dbSUPER 2 +260.4 260400 0 SOX5 SOX13 GATAD2A HMG20B SAP130 CEBPB CEBPG ZNF644 NFIL3 MIER3 INIP SNX30 KIAA1958 ZFP37 ZNF883
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around KIAA1958 on UCSC Golden Path with GeneCards custom track

Promoters for KIAA1958 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000239970 453 2201 HDGF ARID4B SIN3A DMAP1 ZNF2 SLC30A9 CBX5 ZNF143 ZNF207 SP3

Genomic Location for KIAA1958 Gene

Chromosome:
9
Start:
112,486,847 bp from pter
End:
112,669,397 bp from pter
Size:
182,551 bases
Orientation:
Plus strand

Genomic View for KIAA1958 Gene

Genes around KIAA1958 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA1958 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA1958 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1958 Gene

Proteins for KIAA1958 Gene

  • Protein details for KIAA1958 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8K9-K1958_HUMAN
    Recommended name:
    Uncharacterized protein KIAA1958
    Protein Accession:
    Q8N8K9
    Secondary Accessions:
    • B7ZKW6
    • Q2M336
    • Q5T252
    • Q8TF43
    • Q96N02

    Protein attributes for KIAA1958 Gene

    Size:
    716 amino acids
    Molecular mass:
    79212 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB71114.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA1958 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA1958 Gene

Post-translational modifications for KIAA1958 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA1958 Gene

No data available for DME Specific Peptides for KIAA1958 Gene

Domains & Families for KIAA1958 Gene

Gene Families for KIAA1958 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for KIAA1958 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA1958: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for KIAA1958 Gene

Function for KIAA1958 Gene

Phenotypes From GWAS Catalog for KIAA1958 Gene

Gene Ontology (GO) - Molecular Function for KIAA1958 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
GO:0003677 DNA binding IBA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with KIAA1958: view

Phenotypes for KIAA1958 Gene

GenomeRNAi human phenotypes for KIAA1958:
genes like me logo Genes that share phenotypes with KIAA1958: view

Animal Model Products

CRISPR Products

miRNA for KIAA1958 Gene

miRTarBase miRNAs that target KIAA1958

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for KIAA1958
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA1958 Gene

Localization for KIAA1958 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for KIAA1958 gene
Compartment Confidence
nucleus 4
plasma membrane 2
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for KIAA1958 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IBA --
GO:0005737 cytoplasm IBA --
genes like me logo Genes that share ontologies with KIAA1958: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for KIAA1958 Gene

Pathways & Interactions for KIAA1958 Gene

SuperPathways for KIAA1958 Gene

No Data Available

Gene Ontology (GO) - Biological Process for KIAA1958 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription from RNA polymerase II promoter IEA --
genes like me logo Genes that share ontologies with KIAA1958: view

No data available for Pathways by source and SIGNOR curated interactions for KIAA1958 Gene

Drugs & Compounds for KIAA1958 Gene

No Compound Related Data Available

Transcripts for KIAA1958 Gene

Unigene Clusters for KIAA1958 Gene

KIAA1958:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for KIAA1958
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1958 Gene

No ASD Table

Relevant External Links for KIAA1958 Gene

GeneLoc Exon Structure for
KIAA1958
ECgene alternative splicing isoforms for
KIAA1958

Expression for KIAA1958 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for KIAA1958 Gene

Protein differential expression in normal tissues from HIPED for KIAA1958 Gene

This gene is overexpressed in Plasma (52.7), Lymph node (9.5), and Testis (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for KIAA1958 Gene



Protein tissue co-expression partners for KIAA1958 Gene

NURSA nuclear receptor signaling pathways regulating expression of KIAA1958 Gene:

KIAA1958

SOURCE GeneReport for Unigene cluster for KIAA1958 Gene:

Hs.656619

Evidence on tissue expression from TISSUES for KIAA1958 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with KIAA1958: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA1958 Gene

Orthologs for KIAA1958 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1958 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA1958 33 34
  • 99.82 (n)
cow
(Bos Taurus)
Mammalia KIAA1958 34
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA1958 34
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA1958 34
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA1958 34
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia E130308A19Rik 34
  • 61 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA1958 34
  • 47 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA1958 34
  • 49 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii si:ch211-126i22.5 34
  • 24 (a)
OneToOne
Species where no ortholog for KIAA1958 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1958 Gene

ENSEMBL:
Gene Tree for KIAA1958 (if available)
TreeFam:
Gene Tree for KIAA1958 (if available)

Paralogs for KIAA1958 Gene

No data available for Paralogs for KIAA1958 Gene

Variants for KIAA1958 Gene

Sequence variations from dbSNP and Humsavar for KIAA1958 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000012735 -- 112,522,986(+) AACAG(A/G)TGTAG intron-variant
rs1000040225 -- 112,556,695(+) TTTGA(C/T)TGCAA intron-variant
rs1000044836 -- 112,637,713(+) TATAA(A/G)TTTTA intron-variant
rs1000092182 -- 112,556,468(+) TATAG(C/T)ACAGC intron-variant
rs1000114037 -- 112,653,673(+) AGGCG(A/G)GCGGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA1958 Gene

Variant ID Type Subtype PubMed ID
dgv1231n67 CNV gain 20364138
dgv262e55 CNV gain 17911159
dgv4127n106 CNV deletion 24896259
dgv7701n100 CNV gain 25217958
esv1050816 CNV deletion 17803354
esv1174496 CNV insertion 17803354
esv1674209 CNV insertion 17803354
esv1981326 CNV deletion 18987734
esv2333544 CNV deletion 18987734
esv2500783 CNV deletion 19546169
esv2559748 CNV insertion 19546169
esv2663019 CNV deletion 23128226
esv2667240 CNV deletion 23128226
esv2738947 CNV deletion 23290073
esv2738948 CNV deletion 23290073
esv2738949 CNV deletion 23290073
esv2741005 CNV deletion 23290073
esv2759710 CNV gain 17122850
esv2761275 CNV gain 21179565
esv3305 CNV loss 18987735
esv3339732 CNV insertion 20981092
esv3621516 CNV loss 21293372
esv3621517 CNV gain 21293372
esv3621518 CNV gain 21293372
nsv1051625 CNV loss 25217958
nsv1110053 CNV deletion 24896259
nsv1135296 CNV deletion 24896259
nsv1147695 CNV deletion 26484159
nsv416371 CNV deletion 16902084
nsv442163 CNV gain 18776908
nsv466488 CNV loss 19166990
nsv471317 CNV gain 18288195
nsv510204 OTHER sequence alteration 20534489
nsv511430 CNV loss 21212237
nsv515121 CNV gain 21397061
nsv515899 CNV gain+loss 19592680
nsv615197 CNV loss 21841781
nsv615198 CNV gain 21841781
nsv6670 CNV insertion 18451855
nsv6671 CNV deletion 18451855
nsv956109 CNV deletion 24416366
nsv972801 CNV duplication 23825009

Variation tolerance for KIAA1958 Gene

Residual Variation Intolerance Score: 10.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.78; 33.57% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KIAA1958 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
KIAA1958

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA1958 Gene

Disorders for KIAA1958 Gene

Relevant External Links for KIAA1958

Genetic Association Database (GAD)
KIAA1958
Human Genome Epidemiology (HuGE) Navigator
KIAA1958
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA1958

No disorders were found for KIAA1958 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA1958 Gene

Publications for KIAA1958 Gene

  1. Crypton transposons: identification of new diverse families and ancient domestication events. (PMID: 22011512) Kojima KK … Jurka J (Mobile DNA 2011) 2 3 60
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 45 60
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  4. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 60
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60

Products for KIAA1958 Gene

Sources for KIAA1958 Gene

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