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Aliases for KIAA1919 Gene

Aliases for KIAA1919 Gene

  • KIAA1919 2 3
  • NaGLT1 3 4
  • Sodium-Dependent Glucose Transporter 1 3
  • MFSD4B 3

External Ids for KIAA1919 Gene

Previous GeneCards Identifiers for KIAA1919 Gene

  • GC06U990288
  • GC06P111603
  • GC06P111626
  • GC06P111687
  • GC06P111581
  • GC06P109151

Summaries for KIAA1919 Gene

GeneCards Summary for KIAA1919 Gene

KIAA1919 (KIAA1919) is a Protein Coding gene. GO annotations related to this gene include symporter activity. An important paralog of this gene is MFSD4.

UniProtKB/Swiss-Prot for KIAA1919 Gene

  • May function as a sodium-dependent glucose transporter.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1919 Gene

Genomics for KIAA1919 Gene

Regulatory Elements for KIAA1919 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for KIAA1919 Gene

Start:
111,259,279 bp from pter
End:
111,271,167 bp from pter
Size:
11,889 bases
Orientation:
Plus strand

Genomic View for KIAA1919 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KIAA1919 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1919 Gene

Proteins for KIAA1919 Gene

  • Protein details for KIAA1919 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TF39-NAGT1_HUMAN
    Recommended name:
    Sodium-dependent glucose transporter 1
    Protein Accession:
    Q5TF39
    Secondary Accessions:
    • A8K9M0
    • Q8IYB6
    • Q96PW9
    • Q9P0D6

    Protein attributes for KIAA1919 Gene

    Size:
    518 amino acids
    Molecular mass:
    56218 Da
    Quaternary structure:
    No Data Available

neXtProt entry for KIAA1919 Gene

Proteomics data for KIAA1919 Gene at MOPED

Post-translational modifications for KIAA1919 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA1919 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KIAA1919 Gene

Domains for KIAA1919 Gene

Protein Domains for KIAA1919 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q5TF39

UniProtKB/Swiss-Prot:

NAGT1_HUMAN :
  • Q5TF39
Family:
  • Belongs to the major facilitator superfamily.
genes like me logo Genes that share domains with KIAA1919: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for KIAA1919 Gene

Function for KIAA1919 Gene

Molecular function for KIAA1919 Gene

UniProtKB/Swiss-Prot Function: May function as a sodium-dependent glucose transporter.

Gene Ontology (GO) - Molecular Function for KIAA1919 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015293 symporter activity IEA --
genes like me logo Genes that share ontologies with KIAA1919: view

Phenotypes for KIAA1919 Gene

GenomeRNAi human phenotypes for KIAA1919:
genes like me logo Genes that share phenotypes with KIAA1919: view

Animal Model Products

CRISPR Products

miRNA for KIAA1919 Gene

miRTarBase miRNAs that target KIAA1919

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for KIAA1919 Gene

Localization for KIAA1919 Gene

Subcellular locations from UniProtKB/Swiss-Prot for KIAA1919 Gene

Apical cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA1919 Gene COMPARTMENTS Subcellular localization image for KIAA1919 gene
Compartment Confidence
plasma membrane 5
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for KIAA1919 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane --
GO:0016021 integral component of membrane IEA --
GO:0016324 apical plasma membrane IEA --
genes like me logo Genes that share ontologies with KIAA1919: view

Pathways for KIAA1919 Gene

SuperPathways for KIAA1919 Gene

No Data Available

Interacting Proteins for KIAA1919 Gene

Gene Ontology (GO) - Biological Process for KIAA1919 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006814 sodium ion transport IEA --
GO:0008643 carbohydrate transport IEA --
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with KIAA1919: view

No data available for Pathways by source for KIAA1919 Gene

Transcripts for KIAA1919 Gene

mRNA/cDNA for KIAA1919 Gene

(76) Selected AceView cDNA sequences:
(6) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for KIAA1919 Gene

KIAA1919:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for KIAA1919

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for KIAA1919

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1919 Gene

No ASD Table

Relevant External Links for KIAA1919 Gene

GeneLoc Exon Structure for
KIAA1919
ECgene alternative splicing isoforms for
KIAA1919

Expression for KIAA1919 Gene

mRNA expression in normal human tissues for KIAA1919 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for KIAA1919 Gene

SOURCE GeneReport for Unigene cluster for KIAA1919 Gene Hs.400572

genes like me logo Genes that share expressions with KIAA1919: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for KIAA1919 Gene

Orthologs for KIAA1919 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1919 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA1919 35
  • 99.42 (n)
  • 99.23 (a)
KIAA1919 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia KIAA1919 35
  • 87.49 (n)
  • 85.69 (a)
KIAA1919 36
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA1919 35
  • 85.69 (n)
  • 83.37 (a)
KIAA1919 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 2010001E11Rik 36
  • 78 (a)
OneToMany
AA474331 36
  • 72 (a)
OneToMany
AI317395 35
  • 77.65 (n)
  • 77.25 (a)
AI317395 16
AI317395 36
  • 77 (a)
OneToMany
BC021785 36
  • 66 (a)
OneToMany
G630090E17Rik 36
  • 78 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 64 (a)
OneToMany
-- 36
  • 65 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA1919 36
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1559971 35
  • 77.69 (n)
  • 76.47 (a)
chicken
(Gallus gallus)
Aves KIAA1919 35
  • 62.59 (n)
  • 57.88 (a)
KIAA1919 36
  • 48 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA1919 36
  • 57 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.10832 35
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa1919 35
  • 62.86 (n)
  • 57.54 (a)
zebrafish
(Danio rerio)
Actinopterygii zgc:162161 35
  • 56.32 (n)
  • 51.99 (a)
zgc:162161 36
  • 39 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 28 (a)
OneToMany
-- 36
  • 34 (a)
OneToMany
Species with no ortholog for KIAA1919:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1919 Gene

ENSEMBL:
Gene Tree for KIAA1919 (if available)
TreeFam:
Gene Tree for KIAA1919 (if available)

Paralogs for KIAA1919 Gene

Paralogs for KIAA1919 Gene

Pseudogenes.org Pseudogenes for KIAA1919 Gene

genes like me logo Genes that share paralogs with KIAA1919: view

Variants for KIAA1919 Gene

Sequence variations from dbSNP and Humsavar for KIAA1919 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs240985 -- 111,263,428(+) TTATT(C/T)AGTAA intron-variant
rs240986 -- 111,265,852(-) AAAAA(A/T)TATTT intron-variant
rs240987 -- 111,268,552(-) GAACA(C/T)AGTGT utr-variant-3-prime
rs240988 -- 111,268,891(+) TATAT(A/G)TGGCA utr-variant-3-prime
rs240999 -- 111,257,287(-) acaaa(A/C)aaaAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for KIAA1919 Gene

Variant ID Type Subtype PubMed ID
nsv886539 CNV Gain 21882294
nsv886540 CNV Loss 21882294
nsv886541 CNV Loss 21882294

Relevant External Links for KIAA1919 Gene

HapMap Linkage Disequilibrium report
KIAA1919
Human Gene Mutation Database (HGMD)
KIAA1919

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA1919 Gene

Disorders for KIAA1919 Gene

No disorders were found for KIAA1919 Gene.

No data available for UniProtKB/Swiss-Prot for KIAA1919 Gene

Publications for KIAA1919 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PMID: 11572484) Nagase T. … Ohara O. (DNA Res. 2001) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Cloning and characterization of a novel Na+-dependent glucose transporter (NaGLT1) in rat kidney. (PMID: 12590146) Horiba N. … Inui K. (J. Biol. Chem. 2003) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for KIAA1919 Gene

Sources for KIAA1919 Gene

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