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Aliases for KIAA1875 Gene

Subcategory (RNA class) for KIAA1875 Gene


Quality Score for this RNA gene is


Aliases for KIAA1875 Gene

  • KIAA1875 2 3

External Ids for KIAA1875 Gene

Previous GeneCards Identifiers for KIAA1875 Gene

  • GC00U990996
  • GC08P144938
  • GC08P145268
  • GC08P145234
  • GC08P145162
  • GC08P140438

Summaries for KIAA1875 Gene

Entrez Gene Summary for KIAA1875 Gene

  • The function and protein-coding potential of this gene is unknown. The exon combination is based on AB058778.1 for which two possible open reading frames can be predicted (with start codons at nucleotide 26 or 2614). The position of the first ORF stop codon is consistent with a prediction of nonsense-mediated decay. Given the observation of the first ORF and its length, a predicted translation of the second ORF is inconsistent with the translation leaky scanning theory. Therefore, this gene is represented as a non-protein-coding transcript. [provided by RefSeq, Oct 2008]

GeneCards Summary for KIAA1875 Gene

KIAA1875 (KIAA1875) is an RNA Gene, and is affiliated with the ncRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1875 Gene

Genomics for KIAA1875 Gene

Regulatory Elements for KIAA1875 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for KIAA1875 Gene

144,107,726 bp from pter
144,118,315 bp from pter
10,590 bases
Plus strand

Genomic View for KIAA1875 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KIAA1875 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1875 Gene

Proteins for KIAA1875 Gene

  • Protein details for KIAA1875 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    WD repeat-containing protein KIAA1875
    Protein Accession:
    Secondary Accessions:
    • Q96JF2

    Protein attributes for KIAA1875 Gene

    1622 amino acids
    Molecular mass:
    180307 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB47504.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

    Alternative splice isoforms for KIAA1875 Gene


neXtProt entry for KIAA1875 Gene

Proteomics data for KIAA1875 Gene at MOPED

Post-translational modifications for KIAA1875 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for KIAA1875 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for KIAA1875 Gene

Domains for KIAA1875 Gene

Gene Families for KIAA1875 Gene

Protein Domains for KIAA1875 Gene

Suggested Antigen Peptide Sequences for KIAA1875 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



K1875_HUMAN :
  • Contains 6 WD repeats.
  • Contains 6 WD repeats.
genes like me logo Genes that share domains with KIAA1875: view

Function for KIAA1875 Gene

Gene Ontology (GO) - Molecular Function for KIAA1875 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with KIAA1875: view

Phenotypes for KIAA1875 Gene

GenomeRNAi human phenotypes for KIAA1875:
genes like me logo Genes that share phenotypes with KIAA1875: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for KIAA1875 Gene

Localization for KIAA1875 Gene

Subcellular locations from

Jensen Localization Image for KIAA1875 Gene COMPARTMENTS Subcellular localization image for KIAA1875 gene
Compartment Confidence
cytosol 3
nucleus 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA1875 Gene

Pathways for KIAA1875 Gene

SuperPathways for KIAA1875 Gene

No Data Available

Interacting Proteins for KIAA1875 Gene

Selected Interacting proteins: A6NE52-K1875_HUMAN for KIAA1875 Gene via I2D

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for KIAA1875 Gene


No data available for Pathways by source for KIAA1875 Gene

Transcripts for KIAA1875 Gene

mRNA/cDNA for KIAA1875 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(9) Selected AceView cDNA sequences:
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for KIAA1875 Gene

Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1875 Gene

No ASD Table

Relevant External Links for KIAA1875 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for KIAA1875 Gene

mRNA expression in normal human tissues for KIAA1875 Gene

mRNA differential expression in normal tissues according to GTEx for KIAA1875 Gene

This gene is overexpressed in Testis (10.0) and Brain - Cerebellum (5.1).

Protein differential expression in normal tissues for KIAA1875 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (60.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for KIAA1875 Gene

SOURCE GeneReport for Unigene cluster for KIAA1875 Gene Hs.98723

genes like me logo Genes that share expressions with KIAA1875: view

Expression partners for KIAA1875 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for KIAA1875 Gene

Orthologs for KIAA1875 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1875 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia 15 16
(Bos Taurus)
Mammalia KIAA1875 36
  • 65 (a)
(Canis familiaris)
Mammalia -- 36
  • 69 (a)
-- 36
  • 50 (a)
(Monodelphis domestica)
Mammalia KIAA1875 36
  • 35 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 58 (a)
-- 36
  • 45 (a)
-- 36
  • 32 (a)
(Pan troglodytes)
Mammalia KIAA1875 36
  • 98 (a)
(Anolis carolinensis)
Reptilia KIAA1875 36
  • 36 (a)
Species with no ortholog for KIAA1875:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for KIAA1875 Gene

Gene Tree for KIAA1875 (if available)
Gene Tree for KIAA1875 (if available)

Paralogs for KIAA1875 Gene

(2) SIMAP similar genes for KIAA1875 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with KIAA1875: view

No data available for Paralogs for KIAA1875 Gene

Variants for KIAA1875 Gene

Sequence variations from dbSNP and Humsavar for KIAA1875 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs1132230 -- 144,116,298(+) ACCGG(A/G)CTGGT nc-transcript-variant
rs4075064 -- 144,113,593(-) GCCGG(C/T)AAAAC intron-variant
rs4075389 -- 144,112,836(+) GGAGG(C/T)GCTGG intron-variant
rs4977193 -- 144,116,100(-) GGGAC(C/G)GCATG nc-transcript-variant
rs4977194 -- 144,113,019(-) CCCAC(C/G)TGGGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for KIAA1875 Gene

Variant ID Type Subtype PubMed ID
dgv7935n71 CNV Loss 21882294
dgv7940n71 CNV Loss 21882294
nsv891766 CNV Loss 21882294
dgv906n27 CNV Loss 19166990
nsv470249 CNV Loss 18288195
dgv7948n71 CNV Loss 21882294
dgv7949n71 CNV Loss 21882294
dgv7950n71 CNV Loss 21882294
nsv515809 CNV Gain+Loss 19592680
dgv7954n71 CNV Loss 21882294
nsv466014 CNV Loss 19166990
dgv7955n71 CNV Loss 21882294
nsv891807 CNV Loss 21882294
nsv428208 CNV Gain 18775914
nsv891809 CNV Loss 21882294
esv29971 CNV Loss 17803354
dgv2263e1 CNV Complex 17122850
dgv7956n71 CNV Loss 21882294
nsv891812 CNV Loss 21882294
nsv6448 CNV Insertion 18451855
nsv891814 CNV Loss 21882294
nsv824802 CNV Gain 20364138
nsv824803 CNV Gain 20364138

Relevant External Links for KIAA1875 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA1875 Gene

Disorders for KIAA1875 Gene

No disorders were found for KIAA1875 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for KIAA1875 Gene

Publications for KIAA1875 Gene

  1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  4. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 4

Products for KIAA1875 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate KIAA1875
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for KIAA1875
    • Block miRNA regulation of KIAA1875 using miScript Target Protectors

    Sources for KIAA1875 Gene

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