KIAA1755 Gene
protein-coding GIFtS: 39
GCID: GC20M036838 (predicted)
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KIAA1755
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Aliases
for KIAA1755 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| KIAA17551 2 | | RP5-1054A22.31 | | Uncharacterized Protein KIAA17552 |
Export aliases for KIAA1755 gene to outside databasesPrevious GC identifers: GC20M036567 GC20M037479 GC20M037524 GC20M036272 GC20M033575 |
Summaries
for KIAA1755 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for KIAA1755 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIAA1755 gene promoter:
TBP p53 Olf-1 FOXD3 STAT5A HNF-3beta IRF-2 TFIID Zic1 ZIC2/Zic2
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIAA1755
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA1755 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q11.23 Ensembl cytogenetic band: 20q11.23 HGNC cytogenetic band: 20q11.23KIAA1755 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M036838: view genomic region
(about GC identifiers)
Start:
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36,838,890 bp from pter |
End:
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36,889,174 bp from pter |
Size:
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50,285 bases |
Orientation:
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minus strand |
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Proteins
for KIAA1755 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: K1755_HUMAN, Q5JYT7 (See
protein sequence)Recommended Name: Uncharacterized protein KIAA1755 Size: 1200 amino acids; 130846 Da
Secondary accessions: Q9C0A8Explore the universe of human proteins at neXtProt for KIAA1755: NX_Q5JYT7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5JYT7
KIAA1755 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001025035.1
ENSEMBL proteins: ENSP00000279024 ENSP00000393503
Human Recombinant Protein Products:
KIAA1755 Antibody Products:
Assay Products for KIAA1755: |
Protein
Domains /
Families
for KIAA1755 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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KIAA1755 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q5JYT7ProtoNet protein and cluster: Q5JYT7 |
Function
for KIAA1755 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1755 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1755
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: KIAA1755 (NM_001029864) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1755 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KIAA1755 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1755 |
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Pathways & Interactions
for KIAA1755 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA1755
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Drugs & Compounds
for KIAA1755 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KIAA1755
Search CenterWatch for drugs/clinical trials and news about KIAA1755 / K1755
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Transcripts
for KIAA1755 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for KIAA1755 gene: NM_001029864.1 Unigene Cluster for KIAA1755: KIAA1755 Hs.472690 [show with all ESTs]Unigene Representative Sequence: NM_0010298646 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000279024(uc002xhv.1 uc002xhw.1 uc002xhx.1 uc002xhy.1)
ENST00000460881 ENST00000484362 ENST00000487506 ENST00000435901 ENST00000496900(uc002xhz.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1755 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1755
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KIAA1755 (NM_001029864) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1755 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KIAA1755 |
Additional cDNA sequence: AB051542.1 AK096202.1 BC011516.1 BC029137.1 BC033704.1 BC047031.1 8 DOTS entries: DT.40122191 DT.95206966 DT.100018960 DT.101959247 DT.101977401 DT.86846471 DT.99940323 DT.95238816 24/46 AceView cDNA sequences (see all 46): BC047031 AI569989 AK096202 BG057037 BC011516 BQ671533 AI623212 AI365680 AW296491 BF347247 BG818144 BC033704 BM671316 BC029137 AI421251 BF347625 AB051542 AI682445 BE858236 CB154749 BE222799 BE896669 BI756492 BG820568
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1755 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 |
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| SP1: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KIAA1755
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Expression
for KIAA1755 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KIAA1755 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGAATAGCA
About this image
See KIAA1755 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KIAA1755
SOURCE GeneReport for Unigene cluster: Hs.472690
SABiosciences Custom PCR Arrays for KIAA1755
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA1755
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KIAA1755 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA1755 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA1755 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1755 |
Orthologs
for KIAA1755 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of animals.
Orthologs for KIAA1755 gene from 4/15 species (see all 15) About this table
ENSEMBL Gene Tree for KIAA1755 (if available)
TreeFam Gene Tree for KIAA1755 (if available) |
Paralogs
for KIAA1755 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KIAA1755 gene
- KALRN2 ARHGEF252 PLEKHG4B2 MCF2L22 TRIO2 MCF2L2 PLEKHG42 ARHGEF402
- MCF22
1 SIMAP similar gene for KIAA1755 using alignment to 2 protein entries: K1755_HUMAN (see all proteins):PLEKHG4B
KIAA1755 for paralogs About GeneDecksing
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Genomic Variants
for KIAA1755 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for KIAA1755 (36838890 - 36889174 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for KIAA1755: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA1755 |
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Disorders
/ Diseases
for KIAA1755 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 KIAA1755 for disorders About MalaCards
KIAA1755 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: KIAA1755 (1 document)
Export disorders for KIAA1755 gene to outside databases
|
Publications
for KIAA1755 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for KIAA1755 gene integrated from 9 sources:
(articles sorted by number of sources associating them with KIAA1755) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (2000)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)2 Deloukas P....Rogers J. (2001)
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External Searches for KIAA1755 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing KIAA1755 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing KIAA1755 gene
(According to HUGE)
About This Section
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Specialized Databases showing KIAA1755 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for KIAA1755 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for KIAA1755 gene:
Search GeneIP for patents involving KIAA1755
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIAA1755 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KIAA1755 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KIAA1755 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA1755 | | | OriGene Protein Over-expression Lysate for KIAA1755 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KIAA1755 | | OriGene 3'-UTR Clone for KIAA1755 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1755 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1755 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIAA1755 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA1755 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA1755 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIAA1755 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA1755 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA1755 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1755 |
|  |  |  | | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KIAA1755 |
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