KIAA1751 Gene
protein-coding GIFtS: 33
GCID: GC01M001853 (predicted)
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KIAA1751
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Aliases
for KIAA1751 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
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| KIAA17511 2 | | FLJ454761 | | Uncharacterized Protein KIAA17512 |
Export aliases for KIAA1751 gene to outside databasesPrevious GC identifers: GC01M001442 GC01U900052 GC01M9L0050 GC00P9Y0072 GC01M001916 |
Summaries
for KIAA1751 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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-- |
Genomic Views
for KIAA1751 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004350.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIAA1751 gene promoter:
Egr-3 AREB6 NF-1/L NF-AT2 NRSF form 1 NRSF form 2 NF-AT1 NF-AT
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIAA1751
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA1751 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.33 Ensembl cytogenetic band: 1p36.33 HGNC cytogenetic band: 1p36.33KIAA1751 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M001853: view genomic region
(about GC identifiers)
Start:
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1,853,396 bp from pter |
End:
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1,935,276 bp from pter |
Size:
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81,881 bases |
Orientation:
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minus strand |
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Proteins
for KIAA1751 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: K1751_HUMAN, Q9C0B2 (See
protein sequence)Recommended Name: Uncharacterized protein KIAA1751 Size: 762 amino acids; 86956 Da
Secondary accessions: A4VCI2 Q5T2D9 Q5T2E0 Q6ZSJ4Alternative splicing: 3 isoforms: Q9C0B2-1 Q9C0B2-2 Q9C0B2-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for KIAA1751: NX_Q9C0B2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9C0B2
KIAA1751 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001073953.1
ENSEMBL proteins: ENSP00000417061 ENSP00000420396 ENSP00000417421 ENSP00000367853 ENSP00000270720 ENSP00000408078
Human Recombinant Protein Products:
KIAA1751 Antibody Products:
Assay Products for KIAA1751: |
Protein
Domains /
Families
for KIAA1751 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9C0B2 |
Function
for KIAA1751 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1751 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1751
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: KIAA1751 (NM_001080484) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1751 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KIAA1751 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1751 |
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Pathways & Interactions
for KIAA1751 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA1751
|
Drugs & Compounds
for KIAA1751 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KIAA1751
Search CenterWatch for drugs/clinical trials and news about KIAA1751 / K1751
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Transcripts
for KIAA1751 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for KIAA1751 gene: NM_001080484.1 Unigene Cluster for KIAA1751: KIAA1751 Hs.232092 [show with all ESTs]Unigene Representative Sequence: NM_00108048411 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000464311(uc001aik.3 uc001ail.3) ENST00000412120 ENST00000493964
ENST00000493316 ENST00000450874 ENST00000468610 ENST00000461752 ENST00000378592(uc001ain.1)
ENST00000378590 ENST00000270720(uc009vkz.1 uc001aim.1) ENST00000434971
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1751 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1751
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KIAA1751 (NM_001080484) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1751 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KIAA1751 |
Additional cDNA sequence: AB051538.1 AK127388.1 BC139754.1 5 DOTS entries: DT.91962168 DT.101976792 DT.95213435 DT.97823881 DT.121389597 5 AceView cDNA sequences: BQ011193 BQ011569 AK127388 AB051538 AL597773
GeneLoc Exon Structure
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Expression
for KIAA1751 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KIAA1751 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See KIAA1751 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KIAA1751
SOURCE GeneReport for Unigene cluster: Hs.232092
SABiosciences Custom PCR Arrays for KIAA1751
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA1751
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat KIAA1751 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA1751 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA1751 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1751 |
Orthologs
for KIAA1751 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for KIAA1751 gene from 4/16 species (see all 16) About this table
ENSEMBL Gene Tree for KIAA1751 (if available)
TreeFam Gene Tree for KIAA1751 (if available) |
Paralogs
for KIAA1751 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
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Genomic Variants
for KIAA1751 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: K1751_HUMAN, Q9C0B2Polymorphism: PubMed:11214970 sequence (BAB21842) differs from that shown due to a possible polymorphism in position763 that produces a Gln residue instead of a stop codon (dbSNP:rs28548017) and leads to a protein of 768 residueswhose C-terminal sequence is Ser-Gln-Ala-Phe-Asp-Val-Lys instead of Ser
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for KIAA1751 (1853396 - 1935276 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for KIAA1751
3 CNVs: 68654 68652 3276
2 Indels: 44482 68653 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA1751 |
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Disorders
/ Diseases
for KIAA1751 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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Publications
for KIAA1751 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KIAA1751 gene integrated from 9 sources:
(articles sorted by number of sources associating them with KIAA1751) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2 Nagase T.... Ohara O. (2000)
- The BTB and CNC homology 1 (BACH1) target genes are i nvolved in the oxidative stress response and in control of the cell cycle. (PubMed id 21555518)1 Warnatz H.J....Yaspo M.L. (2011)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for KIAA1751 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing KIAA1751 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing KIAA1751 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing KIAA1751 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KIAA1751 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for KIAA1751 gene:
Search GeneIP for patents involving KIAA1751
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIAA1751 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for KIAA1751 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KIAA1751 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA1751 | | | OriGene Protein Over-expression Lysate for KIAA1751 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KIAA1751 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1751 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1751 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIAA1751 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA1751 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA1751 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIAA1751 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA1751 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA1751 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1751 |
|  |  |  | | | | Search ThermoFisher Antibodies for KIAA1751 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat KIAA1751 |
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