KIAA1737 Gene
protein-coding GIFtS: 38
GCID: GC14P077564
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KIAA1737
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Aliases
for KIAA1737 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| KIAA17371 2 | | Uncharacterized Protein KIAA17372 |
Export aliases for KIAA1737 gene to outside databasesPrevious GC identifers: GC14P075070 GC14P071381 GC14P075554 GC14P076634 GC14P057732 |
Summaries
for KIAA1737 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for KIAA1737 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the KIAA1737 gene promoter:
NF-1 AML1a MEF-2 Ik-3 LCR-F1 Arnt MEF-2A SRY Cart-1 aMEF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for KIAA1737
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA1737 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q24.3 Ensembl cytogenetic band: 14q24.3 HGNC cytogenetic band: 14q24.3KIAA1737 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P077564: view genomic region
(about GC identifiers)
Start:
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77,564,440 bp from pter |
End:
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77,583,630 bp from pter |
Size:
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19,191 bases |
Orientation:
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plus strand |
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Proteins
for KIAA1737 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: K1737_HUMAN, Q9C0C6 (See
protein sequence)Recommended Name: Uncharacterized protein KIAA1737 Size: 399 amino acids; 42692 Da
Sequence caution: Sequence=BAB21828.1; Type=Erroneous initiation;
Secondary accessions: B2RCI1 Q8N389 Q8NDZ1Explore the universe of human proteins at neXtProt for KIAA1737: NX_Q9C0C6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9C0C6
KIAA1737 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_219494.2
ENSEMBL proteins: ENSP00000355319 ENSP00000451997 ENSP00000450972 ENSP00000451522 ENSP00000452589 ENSP00000452380 ENSP00000451493
Human Recombinant Protein Products:
KIAA1737 Antibody Products:
Assay Products for KIAA1737: |
Protein
Domains /
Families
for KIAA1737 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9C0C6 |
Function
for KIAA1737 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1737 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1737
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: KIAA1737 (NM_033426) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1737 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA1737 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1737 |
|
Pathways & Interactions
for KIAA1737 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA1737
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
2 Interacting proteins for KIAA1737 (Q9C0C63 ENSP000003553194) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for KIAA1737 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for KIAA1737
Search CenterWatch for drugs/clinical trials and news about KIAA1737 / K1737
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Transcripts
for KIAA1737 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for KIAA1737 gene: NM_033426.2 Unigene Cluster for KIAA1737: KIAA1737 Hs.709066 [show with all ESTs]Unigene Representative Sequence: NM_0334268 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000361786(uc001xtc.1 uc001xtd.3) ENST00000555437 ENST00000556863
ENST00000555611 ENST00000554658 ENST00000557115 ENST00000554447 ENST00000555200
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1737 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1737
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: KIAA1737 (NM_033426) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1737 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA1737 |
Additional cDNA sequence: AB051524.1 AK024737.1 AK096603.1 AK315124.1 AL834514.1 BC037300.2 7 DOTS entries: DT.214665 DT.100750038 DT.97811165 DT.120748757 DT.120748778 DT.120748755 DT.91647668 24/113 AceView cDNA sequences (see all 113): AI056269 AW167032 AA829349 N36912 NM_033426 N46190 CK005246 BP362944 AA961922 BM967085 AA991303 BM887819 AI858359 BP351793 CA430899 BU619760 AI745356 CA313709 AA757352 AA904427 AA897170 BG231726 BU734091 CK823405
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1737 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | · | 7f | · | 7g |
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| SP1: | | | | | | | | | | | - | | - | | | | | | - | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | - | | | | - | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | - | | | | - | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for KIAA1737
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Expression
for KIAA1737 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| KIAA1737 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See KIAA1737 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for KIAA1737
SOURCE GeneReport for Unigene cluster: Hs.709066
SABiosciences Custom PCR Arrays for KIAA1737
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA1737
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat KIAA1737 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA1737 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA1737 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1737 |
Orthologs
for KIAA1737 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for KIAA1737 gene from 4/11 species (see all 11) About this table
ENSEMBL Gene Tree for KIAA1737 (if available)
TreeFam Gene Tree for KIAA1737 (if available) |
Paralogs
for KIAA1737 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for KIAA1737 gene
- ENSG000002591642
KIAA1737 for paralogs About GeneDecksing
|
Genomic Variants
for KIAA1737 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for KIAA1737 (77564440 - 77583630 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for KIAA1737
1 CNV: 4840 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA1737 |
|
Disorders
/ Diseases
for KIAA1737 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for KIAA1737 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for KIAA1737 gene integrated from 9 sources:
(articles sorted by number of sources associating them with KIAA1737) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2 Nagase T.... Ohara O. (2000)
- Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for KIAA1737 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing KIAA1737 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing KIAA1737 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing KIAA1737 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for KIAA1737 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for KIAA1737 gene:
Search GeneIP for patents involving KIAA1737
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for KIAA1737 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for KIAA1737 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for KIAA1737 | | | OriGene Protein Over-expression Lysate for KIAA1737 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for KIAA1737 | | OriGene 3'-UTR Clone for KIAA1737 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1737 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for KIAA1737 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for KIAA1737 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIAA1737 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing KIAA1737 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat KIAA1737 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat KIAA1737 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat KIAA1737 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat KIAA1737 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1737 |
|  |  |  | | | | Search ThermoFisher Antibodies for KIAA1737 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat KIAA1737 |
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