KIAA1715 Gene
protein-coding GIFtS : 46
GCID: GC02 M176788
KIAA1715
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Aliasesfor KIAA1715 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases KIAA1715 1 2 2310011O18Rik2 Ul1 2 4921514L11Rik2 Ulnaless1 Lunapark2 LNP2 5 Protein Lunapark2
Export aliases for KIAA1715 gene to outside databases Previous GC identifers: GC02M174842 GC02M175451 GC02M176995 GC02M176992 GC02M176615 GC02M176496 GC02M168667
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Summariesfor KIAA1715 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: LNP_HUMAN, Q9C0E8 Function : May be involved in limb and central nervous system development (By similarity)
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Genomic Viewsfor KIAA1715 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000002.11 NC_018913.1 NT_005403.17 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the KIAA1715 gene promoter: HOXA9 GATA-3 Pax-5 FOXD3 HNF-3beta GATA-2 GATA-1 C/EBPalpha Meis-1a Pax-4a Other transcription factors Search SABiosciences Chromatin IP Primers for KIAA1715 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat KIAA1715
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 2q31 Ensembl cytogenetic band: 2q31.1 HGNC cytogenetic band: 2q31 KIAA1715 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 2 GeneLoc Exon Structure
GeneLoc location for GC02M176788: view genomic region
(about GC identifiers )
Start:
176,788,620 bp from pter
End:
176,867,567 bp from pter
Size:
78,948 bases
Orientation:
minus strand
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Proteinsfor KIAA1715 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: LNP_HUMAN, Q9C0E8 (See
protein sequence )Recommended Name: Protein lunapark Size : 428 amino acids; 47740 Da
Subcellular location : Membrane; Multi-pass membrane protein (Potential)
Sequence caution : Sequence=BAB21806.1; Type=Erroneous initiation;
Secondary accessions : Q2M2V8 Q2YD99 Q658W8 Q8N5V9 Q96MS5Alternative splicing : 3 isoforms : Q9C0E8-1 Q9C0E8-2 Q9C0E8-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for KIAA1715: NX_Q9C0E8 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9C0E8 KIAA1715 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_085153.1 ENSEMBL proteins: ENSP00000272748 ENSP00000386237 ENSP00000388507 ENSP00000376323 ENSP00000388262 ENSP00000440905 ENSP00000445464 Human Recombinant Protein Products: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
KIAA1715 for ontologies About GeneDecksing KIAA1715 Antibody Products: Assay Products for KIAA1715:
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Protein
Domains / Familiesfor KIAA1715 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
KIAA1715 for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q9C0E8 ProtoNet protein and cluster: Q9C0E8
UniProtKB/Swiss-Prot: LNP_HUMAN, Q9C0E8 Similarity : Belongs to the lunapark family
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Functionfor KIAA1715 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: LNP_HUMAN, Q9C0E8 Function : May be involved in limb and central nervous system development (By similarity)
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for KIAA1715 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for KIAA1715 (see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: KIAA1715 (NM_030650 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1715 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat KIAA1715
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1715
Animal Models: 5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Lnp) :
KIAA1715 for phenotypes About GeneDecksing
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Pathways & Interactionsfor KIAA1715 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA1715 STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)3 Interacting proteins for KIAA1715 (Q9C0E8 1 , 3 ENSP00000272748 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 4 biological process terms (GO ID links to tree view) : About this table
KIAA1715 for ontologies About GeneDecksing
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Drugs & Compoundsfor KIAA1715 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for KIAA1715 Search CenterWatch for drugs/clinical trials and news about KIAA1715 / LNP
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Transcriptsfor KIAA1715 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for KIAA1715 gene: NM_030650.1 Unigene Cluster for KIAA1715:
KIAA1715 Hs.209561 [show with all ESTs ] Unigene Representative Sequence: CR936742 13 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000272748 (uc002ukc.1 uc010zer.1 uc010fqw.1 uc010zes.1 uc002ukd.1 uc010zet.1 )ENST00000409660 ENST00000479012 ENST00000475515 ENST00000431754 ENST00000489827 ENST00000480788 ENST00000392540 ENST00000483230 ENST00000445472 ENST00000466445 ENST00000544803 ENST00000535310 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for KIAA1715 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for KIAA1715 (see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: KIAA1715 (NM_030650 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1715 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat KIAA1715
Additional cDNA sequence: AB051502.1 AK056532.1 AK096916.1 AK301947.1 AK302833.1 AL832947.1 BC031530.1 BC064661.1 BC105132.1 BC105134.1 BC110329.1 BC143681.1 BC143683.1 CR936742.1
7 DOTS entries : DT.210972 DT.95269096
DT.99984350 DT.120945279 DT.120945317 DT.75121937 DT.100798083 24/134 AceView cDNA sequences (see all 134 ):
N66911 BG389124 CB130256 AW502057 CF142475 BM700102 AA808150 AI057618 AL133768 AA321071 AI814567 AI274480 BQ009330 AA744541 AA252972 BQ637099 Z38638 AI299887 BC031530 BU616609 NM_030650 AL045627 AA482636 AA886876 GeneLoc Exon Structure 3 Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1715 About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b ^ 14 SP1 :       -   -               -           SP2 :   -                               SP3 :                                
ECgene alternative splicing isoforms for KIAA1715
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Expression for KIAA1715 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section KIAA1715 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: ATTGCCTTCT
About this image KIAA1715 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table Stem Cell Differentiation: 1 LifeMap Cell Name Category White adipocyte-like cells (Differentiation of ... )Adipose Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See KIAA1715 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for KIAA1715 SOURCE GeneReport for Unigene cluster: Hs.209561 SABiosciences Custom PCR Arrays for KIAA1715 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for KIAA1715Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat KIAA1715 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat KIAA1715 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat KIAA1715 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1715
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Orthologsfor KIAA1715 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for KIAA1715 gene from 9/27 species (see all 27 ) About this table
ENSEMBL Gene Tree for KIAA1715 (if available)TreeFam Gene Tree for KIAA1715 (if available)
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Paralogsfor KIAA1715 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor KIAA1715 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 2 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for KIAA1715 (176788620 - 176867567 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for KIAA1715: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing KIAA1715
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Disorders
/ Diseasesfor KIAA1715 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
KIAA1715 for disorders About GeneDecksing
OMIM gene information: 610236
OMIM disorders : --1 disease for KIAA1715 : About MalaCards neuronitis Export disorders for KIAA1715 gene to outside databases
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Publicationsfor KIAA1715 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for KIAA1715 gene, integrated from 9 sources (see all 16 ): (articles sorted by number of sources associating them with KIAA1715) Utopia : connect your pdf to the dynamic world of online information
Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970) 1 , 2 , 3 Nagase T.... Ohara O. (2000) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) ER network formation requires a balance of the dynamin -like GTPase Sey1p and the Lunapark family member Lnp1p. (PubMed id 22729086) 1 Chen S....Ferro-Novick S. (2012) Initial characterization of the human central proteome. (PubMed id 21269460) 2 Burkard T.R.... Colinge J. (2011) A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473) 1 Wagner S.A....Choudhary C. (2011) Strategy for comprehensive identification of human N-myristoylated proteins using an insect cell-free protein synthesis system. (PubMed id 20213681) 2 Suzuki T.... Utsumi T. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231) 2 Olsen J.V....Mann M. (2010) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332) 2 Mayya V.... Han D.K. (2009) Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201) 1 Abdelmohsen K....Gorospe M. (2009)
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External Searches for KIAA1715 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing KIAA1715 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing KIAA1715 gene
(According to HUGE )
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Specialized Databases showing KIAA1715 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for KIAA1715 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for KIAA1715 gene: Search GeneIP for patents involving KIAA1715 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor KIAA1715 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIAA1715 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing KIAA1715 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat KIAA1715 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat KIAA1715 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat KIAA1715 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat KIAA1715
KIAA1715 Proteins, Antibodies, CLIAs, and ELISAs
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