External Ids for KIAA1598 Gene
GeneCards Summary for KIAA1598 Gene
UniProtKB/Swiss-Prot for KIAA1598 Gene
Involved in the generation of internal asymmetric signals required for neuronal polarization. Acts upstream of PI3K (phosphoinositide 3-kinase), by being required for spatially localized PI3K activity. Accumulates asymmetrically in a single neurite before polarization, leading to axon induction for polarization, its absence from the nascent axons siblings by competition preventing the formation of surplus axons (By similarity).