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Aliases for KIAA1551 Gene

Aliases for KIAA1551 Gene

  • KIAA1551 2 3
  • C12orf35 3 4
  • Chromosome 12 Open Reading Frame 35 2
  • Uncharacterized Protein C12orf35 3
  • UTA2-1 3

External Ids for KIAA1551 Gene

Previous HGNC Symbols for KIAA1551 Gene

  • C12orf35

Previous GeneCards Identifiers for KIAA1551 Gene

  • GC12P032113

Summaries for KIAA1551 Gene

GeneCards Summary for KIAA1551 Gene

KIAA1551 (KIAA1551) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1551 Gene

Genomics for KIAA1551 Gene

Regulatory Elements for KIAA1551 Gene

Promoters for KIAA1551 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around KIAA1551 on UCSC Golden Path with GeneCards custom track

Genomic Location for KIAA1551 Gene

Chromosome:
12
Start:
31,959,370 bp from pter
End:
31,993,107 bp from pter
Size:
33,738 bases
Orientation:
Plus strand

Genomic View for KIAA1551 Gene

Genes around KIAA1551 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
KIAA1551 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for KIAA1551 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1551 Gene

Proteins for KIAA1551 Gene

  • Protein details for KIAA1551 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HCM1-K1551_HUMAN
    Recommended name:
    Uncharacterized protein KIAA1551
    Protein Accession:
    Q9HCM1
    Secondary Accessions:
    • B2RTU5
    • Q4KN17
    • Q9NVL6
    • Q9NWP9

    Protein attributes for KIAA1551 Gene

    Size:
    1747 amino acids
    Molecular mass:
    194857 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA91330.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAA91734.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB13377.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the C-terminal part.; Evidence={ECO:0000305};

neXtProt entry for KIAA1551 Gene

Proteomics data for KIAA1551 Gene at MOPED

Post-translational modifications for KIAA1551 Gene

  • Ubiquitination at Lys 8, Lys 204, Lys 233, Lys 275, Lys 299, Lys 341, Lys 390, Lys 398, Lys 404, Lys 442, Lys 450, Lys 576, Lys 658, Lys 772, Lys 777, Lys 793, and Lys 815
  • Modification sites at PhosphoSitePlus

Other Protein References for KIAA1551 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KIAA1551 Gene

Domains & Families for KIAA1551 Gene

Gene Families for KIAA1551 Gene

Protein Domains for KIAA1551 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with KIAA1551: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for KIAA1551 Gene

Function for KIAA1551 Gene

Phenotypes for KIAA1551 Gene

genes like me logo Genes that share phenotypes with KIAA1551: view

Animal Model Products

CRISPR Products

miRNA for KIAA1551 Gene

miRTarBase miRNAs that target KIAA1551

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA1551 Gene

Localization for KIAA1551 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for KIAA1551 Gene COMPARTMENTS Subcellular localization image for KIAA1551 gene
Compartment Confidence
nucleus 4
cytosol 3
cytoskeleton 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA1551 Gene

Pathways & Interactions for KIAA1551 Gene

SuperPathways for KIAA1551 Gene

No Data Available

Interacting Proteins for KIAA1551 Gene

Gene Ontology (GO) - Biological Process for KIAA1551 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for KIAA1551 Gene

Drugs & Compounds for KIAA1551 Gene

No Compound Related Data Available

Transcripts for KIAA1551 Gene

Unigene Clusters for KIAA1551 Gene

KIAA1551:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1551 Gene

No ASD Table

Relevant External Links for KIAA1551 Gene

GeneLoc Exon Structure for
KIAA1551
ECgene alternative splicing isoforms for
KIAA1551

Expression for KIAA1551 Gene

mRNA expression in normal human tissues for KIAA1551 Gene

mRNA differential expression in normal tissues according to GTEx for KIAA1551 Gene

This gene is overexpressed in Whole Blood (x8.0).

Protein differential expression in normal tissues from HIPED for KIAA1551 Gene

This gene is overexpressed in Plasma (58.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for KIAA1551 Gene



SOURCE GeneReport for Unigene cluster for KIAA1551 Gene Hs.445129

genes like me logo Genes that share expression patterns with KIAA1551: view

Protein tissue co-expression partners for KIAA1551 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for KIAA1551 Gene

Orthologs for KIAA1551 Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1551 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA1551 36
  • 98 (a)
OneToOne
KIAA1551 35
  • 99.26 (n)
  • 98.57 (a)
cow
(Bos Taurus)
Mammalia C5H12orf35 35
  • 78.33 (n)
  • 63.96 (a)
KIAA1551 36
  • 62 (a)
OneToOne
dog
(Canis familiaris)
Mammalia KIAA1551 36
  • 63 (a)
OneToOne
C27H12orf35 35
  • 78.2 (n)
  • 64.24 (a)
mouse
(Mus musculus)
Mammalia 2810474O19Rik 16
2810474O19Rik 36
  • 51 (a)
OneToOne
2810474O19Rik 35
  • 70.52 (n)
  • 54.61 (a)
oppossum
(Monodelphis domestica)
Mammalia KIAA1551 36
  • 31 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA1551 36
  • 44 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1309621 35
  • 69.74 (n)
  • 54.88 (a)
chicken
(Gallus gallus)
Aves KIAA1551 36
  • 19 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA1551 36
  • 17 (a)
OneToOne
Species with no ortholog for KIAA1551:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for KIAA1551 Gene

ENSEMBL:
Gene Tree for KIAA1551 (if available)
TreeFam:
Gene Tree for KIAA1551 (if available)

Paralogs for KIAA1551 Gene

Pseudogenes.org Pseudogenes for KIAA1551 Gene

genes like me logo Genes that share paralogs with KIAA1551: view

No data available for Paralogs for KIAA1551 Gene

Variants for KIAA1551 Gene

Sequence variations from dbSNP and Humsavar for KIAA1551 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs7298803 - 31,981,130(+) ATCCA(A/G)TTTCA reference, missense
rs2388981 - 31,981,273(+) ACTCA(A/C/T)AATTT reference, missense
rs12320740 - 31,981,559(+) AGTGT(A/G)TATCT reference, missense
rs2166807 - 31,981,704(-) AATTT(A/G)GAAGC reference, missense
rs16919122 - 31,981,881(+) GAGTC(A/G)AGAAA reference, missense

Variation tolerance for KIAA1551 Gene

Residual Variation Intolerance Score: 98.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.40; 92.75% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for KIAA1551 Gene

HapMap Linkage Disequilibrium report
KIAA1551

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for KIAA1551 Gene

Disorders for KIAA1551 Gene

Relevant External Links for KIAA1551

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
KIAA1551

No disorders were found for KIAA1551 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA1551 Gene

Publications for KIAA1551 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 67
  2. Towards effective and safe immunotherapy after allogeneic stem cell transplantation: identification of hematopoietic-specific minor histocompatibility antigen UTA2-1. (PMID: 23079962) Oostvogels R. … Mutis T. (Leukemia 2013) 2 3
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  4. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PMID: 17043677) Camargo L.M. … Brandon N.J. (Mol. Psychiatry 2007) 3
  5. Distinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genes. (PMID: 17567985) Tsuritani K. … Suzuki Y. (Genome Res. 2007) 3

Products for KIAA1551 Gene

Sources for KIAA1551 Gene

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