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Aliases for KIAA1549L Gene

Aliases for KIAA1549L Gene

  • KIAA1549-Like 2 3
  • C11orf41 3 4 6
  • C11orf69 3 4
  • G2 3 6
  • Chromosome 11 Open Reading Frame 69 2
  • Chromosome 11 Open Reading Frame 41 2
  • Uncharacterized Protein C11orf69 3
  • UPF0606 Protein KIAA1549L 3
  • UPF0606 Protein C11orf41 3

External Ids for KIAA1549L Gene

Previous Symbols for KIAA1549L Gene

  • C11orf69
  • C11orf41

Summaries for KIAA1549L Gene

GeneCards Summary for KIAA1549L Gene

KIAA1549L (KIAA1549-Like) is a Protein Coding gene. Among its related pathways are Development VEGF signaling via VEGFR2 - generic cascades. An important paralog of this gene is KIAA1549.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1549L Gene

Genomics for KIAA1549L Gene

Genomic Location for KIAA1549L Gene

Start:
33,542,072 bp from pter
End:
33,674,102 bp from pter
Size:
132,031 bases
Orientation:
Plus strand

Genomic View for KIAA1549L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for KIAA1549L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for KIAA1549L Gene

No data available for Regulatory Elements for KIAA1549L Gene

Proteins for KIAA1549L Gene

  • Protein details for KIAA1549L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZVL6-K154L_HUMAN
    Recommended name:
    UPF0606 protein KIAA1549L
    Protein Accession:
    Q6ZVL6
    Secondary Accessions:
    • B0QYU0

    Protein attributes for KIAA1549L Gene

    Size:
    1849 amino acids
    Molecular mass:
    198999 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for KIAA1549L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for KIAA1549L Gene

Proteomics data for KIAA1549L Gene at MOPED

Post-translational modifications for KIAA1549L Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Ser105, Thr638, Thr644, Ser650, Ser651, Ser656, Thr753, and Thr759

Other Protein References for KIAA1549L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for KIAA1549L Gene

Domains for KIAA1549L Gene

Protein Domains for KIAA1549L Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

K154L_HUMAN
Family:
  • Belongs to the UPF0606 family.:
    • Q6ZVL6
genes like me logo Genes that share domains with KIAA1549L: view

No data available for Gene Families for KIAA1549L Gene

Function for KIAA1549L Gene

genes like me logo Genes that share phenotypes with KIAA1549L: view

miRNA for KIAA1549L Gene

miRTarBase miRNAs that target KIAA1549L

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for KIAA1549L Gene

Localization for KIAA1549L Gene

Subcellular locations from UniProtKB/Swiss-Prot for KIAA1549L Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for KIAA1549L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with KIAA1549L: view

Pathways for KIAA1549L Gene

genes like me logo Genes that share pathways with KIAA1549L: view

Pathways by source for KIAA1549L Gene

1 R&D Systems pathway for KIAA1549L Gene

Interacting Proteins for KIAA1549L Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000315295%0d%0a9606.ENSP00000339007%0d%0a9606.ENSP00000244769%0d%0a
Selected Interacting proteins: ENSP00000315295 Q6ZVL6-K154L_HUMAN for KIAA1549L Gene via STRING I2D

Gene Ontology (GO) - Biological Process for KIAA1549L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002230 positive regulation of defense response to virus by host IMP 22020285
GO:0098779 activation of mitophagy in response to mitochondrial depolarization IMP 22020285
genes like me logo Genes that share ontologies with KIAA1549L: view

Transcripts for KIAA1549L Gene

Unigene Clusters for KIAA1549L Gene

KIAA1549-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for KIAA1549L Gene

No ASD Table

Relevant External Links for KIAA1549L Gene

GeneLoc Exon Structure for
KIAA1549L
ECgene alternative splicing isoforms for
KIAA1549L

Expression for KIAA1549L Gene

mRNA expression in normal human tissues for KIAA1549L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for KIAA1549L Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (8.9), Brain - Cortex (8.2), and Brain - Anterior cingulate cortex (BA24) (7.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for KIAA1549L Gene

SOURCE GeneReport for Unigene cluster for KIAA1549L Gene Hs.502266

genes like me logo Genes that share expressions with KIAA1549L: view

Orthologs for KIAA1549L Gene

This gene was present in the common ancestor of chordates.

Orthologs for KIAA1549L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia KIAA1549L 36
  • 96.74 (n)
  • 95.78 (a)
KIAA1549L 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C15H11orf41 36
  • 84.73 (n)
  • 80.66 (a)
KIAA1549L 37
  • 80 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C18H11orf41 36
  • 85.1 (n)
  • 80.64 (a)
KIAA1549L 37
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia D430041D05Rik 36
  • 85.91 (n)
  • 89.79 (a)
D430041D05Rik 16
D430041D05Rik 37
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia KIAA1549L 37
  • 68 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia KIAA1549L 37
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100362814 36
  • 80.98 (n)
  • 76.41 (a)
chicken
(Gallus gallus)
Aves KIAA1549L 37
  • 69 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia KIAA1549L 37
  • 69 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa1549l 36
  • 63.36 (n)
  • 62.36 (a)
Str.5692 36
zebrafish
(Danio rerio)
Actinopterygii KIAA1549L (3 of 3) 37
  • 57 (a)
OneToMany
kiaa1549la 36
  • 57.5 (n)
  • 49.44 (a)
kiaa1549la 37
  • 37 (a)
OneToMany
kiaa1549lb 37
  • 42 (a)
OneToMany
Species with no ortholog for KIAA1549L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for KIAA1549L Gene

ENSEMBL:
Gene Tree for KIAA1549L (if available)
TreeFam:
Gene Tree for KIAA1549L (if available)

Paralogs for KIAA1549L Gene

Paralogs for KIAA1549L Gene

Pseudogenes.org Pseudogenes for KIAA1549L Gene

genes like me logo Genes that share paralogs with KIAA1549L: view

Variants for KIAA1549L Gene

Sequence variations from dbSNP and Humsavar for KIAA1549L Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs20450 -- 33,550,923(+) TGAAC(A/G)AGAAC intron-variant
rs723026 -- 33,621,260(-) AACTC(C/T)TGTTC intron-variant
rs735327 -- 33,579,035(-) TGCTA(C/T)GGTGT intron-variant
rs761433 -- 33,598,229(-) CTCTG(A/T)CACAC intron-variant
rs761434 -- 33,598,226(-) TGACA(C/G)ACACA intron-variant

Relevant External Links for KIAA1549L Gene

HapMap Linkage Disequilibrium report
KIAA1549L

No data available for Structural Variations from Database of Genomic Variants (DGV) for KIAA1549L Gene

Disorders for KIAA1549L Gene

No disorders were found for KIAA1549L Gene.

No data available for UniProtKB/Swiss-Prot for KIAA1549L Gene

Publications for KIAA1549L Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PMID: 16713569) Lim J. … Zoghbi H.Y. (Cell 2006) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for KIAA1549L Gene

Sources for KIAA1549L Gene

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