Aliases for KIAA1522 Gene
External Ids for KIAA1522 Gene
- HGNC: 29301
- Entrez Gene: 57648
- Ensembl: ENSG00000162522
- UniProtKB: Q9P206
Previous GeneCards Identifiers for KIAA1522 Gene
- GC01P033050
- GC01P032186
- GC01P032658
- GC01P032888
- GC01P032980
- GC01P033207
- GC01P031322
Summaries for KIAA1522 Gene
GeneCards Summary for KIAA1522 Gene
KIAA1522 (KIAA1522) is a Protein Coding gene.
Additional gene information for KIAA1522 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for KIAA1522 Gene
Genomics for KIAA1522 Gene
GeneHancer (GH) Regulatory Elements for KIAA1522 Gene
Promoters and enhancers for KIAA1522 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around KIAA1522 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for KIAA1522 Gene
Genomic Locations for KIAA1522 Gene
- chr1:32,741,885-32,774,970
- (GRCh38/hg38)
- Size:
- 33,086 bases
- Orientation:
- Plus strand
- chr1:33,207,486-33,240,571
- (GRCh37/hg19)
Genomic View for KIAA1522 Gene
Genes around KIAA1522 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p35.1 by Ensembl
- 1p35.1 by Entrez Gene
- 1p35.1 by HGNC
KIAA1522 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)


RefSeq DNA sequence for KIAA1522 Gene
Proteins for KIAA1522 Gene
-
Protein details for KIAA1522 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9P206-K1522_HUMAN
- Recommended name:
- Uncharacterized protein KIAA1522
- Protein Accession:
- Q9P206
- B4DQU8
- B5MDY0
- C9JH84
- Q8TCQ0
Protein attributes for KIAA1522 Gene
- Size:
- 1035 amino acids
- Molecular mass:
- 107095 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAA96046.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for KIAA1522 Gene
Post-translational modifications for KIAA1522 Gene
No Post-translational modifications
Other Protein References for KIAA1522 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for KIAA1522
- Novus Biologicals Antibodies for KIAA1522
- Invitrogen Antibodies for KIAA1522
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Protein Products
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- Search GeneTex for Proteins for KIAA1522
Assay Products
No data available for DME Specific Peptides for KIAA1522 Gene
Domains & Families for KIAA1522 Gene
Gene Families for KIAA1522 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for KIAA1522 Gene
- ProtoNet:
Suggested Antigen Peptide Sequences for KIAA1522 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for KIAA1522 Gene
Function for KIAA1522 Gene
Phenotypes for KIAA1522 Gene
- GenomeRNAi human phenotypes for KIAA1522:
Animal Model Products
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-
-
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CRISPR Products
-
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-
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miRNA for KIAA1522 Gene
- miRTarBase miRNAs that target KIAA1522
-
- hsa-mir-335-5p (MIRT018868)
- hsa-mir-1-3p (MIRT024038)
- hsa-mir-218-5p (MIRT440379)
- hsa-mir-6869-5p (MIRT444922)
- hsa-mir-1253 (MIRT444923)
- hsa-mir-3123 (MIRT444924)
- hsa-mir-8087 (MIRT444925)
- hsa-mir-3925-5p (MIRT444926)
- hsa-mir-3924 (MIRT511324)
- hsa-mir-190a-3p (MIRT511325)
- hsa-mir-5011-5p (MIRT511326)
- hsa-mir-1277-5p (MIRT511327)
- hsa-mir-3133 (MIRT511328)
- hsa-mir-186-5p (MIRT511329)
- hsa-mir-3682-5p (MIRT522869)
miRNA Products
- Search ViGene Biosciences for KIAA1522
Inhibitory RNA Products
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Clone Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available KIAA1522 gene related products
- orf clones - Search results for available KIAA1522 gene related products
- Applied Biological Materials Clones for KIAA1522
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for KIAA1522
-
ViGene Biosciences adenoviral particle packaged cDNA for KIAA1522 gene
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-
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No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for KIAA1522 Gene
Localization for KIAA1522 Gene
- Cell Junctions (3)
- Plasma membrane (3)
- Nucleoplasm (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for KIAA1522 Gene
Pathways & Interactions for KIAA1522 Gene
No Data Available
Interacting Proteins for KIAA1522 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0030154 | cell differentiation | IBA | -- |
No data available for Pathways by source and SIGNOR curated interactions for KIAA1522 Gene
Transcripts for KIAA1522 Gene
mRNA/cDNA for KIAA1522 Gene
- (6) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (229) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for KIAA1522
- genomics-online: gRNA clones - Search results for available KIAA1522 gene related products
- Applied Biological Materials CRISPR for KIAA1522
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for KIAA1522
- GenScript: Design CRISPR guide RNA sequences for KIAA1522
miRNA Products
- Search ViGene Biosciences for KIAA1522
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for KIAA1522
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- genomics-online: shRNA clones - Search results for available KIAA1522 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for KIAA1522 gene
Clone Products
-
OriGene ORF clones in human for KIAA1522
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- VectorBuilder custom plasmid, inducible vectors for KIAA1522
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for KIAA1522
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available KIAA1522 gene related products
- orf clones - Search results for available KIAA1522 gene related products
- Applied Biological Materials Clones for KIAA1522
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for KIAA1522 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
mRNA differential expression in normal tissues according to GTEx for KIAA1522 Gene
This gene is overexpressed in Adrenal Gland (x4.0).
This gene is overexpressed in Lung (24.1), Placenta (17.4), and Pancreas (8.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for KIAA1522 Gene
NURSA nuclear receptor signaling pathways regulating expression of KIAA1522 Gene:
KIAA1522SOURCE GeneReport for Unigene cluster for KIAA1522 Gene:
Hs.591502Evidence on tissue expression from TISSUES for KIAA1522 Gene
- Nervous system(4.2)
- Liver(4.1)
Primer Products
-
OriGene qPCR primer pairs for KIAA1522
- genomics-online: primer clones - Search results for available KIAA1522 gene related products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for KIAA1522 Gene
Orthologs for KIAA1522 Gene
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | KIAA1522 33 34 |
|
||
cow (Bos Taurus) |
Mammalia | KIAA1522 33 34 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | KIAA1522 34 |
|
OneToOne | |
dog (Canis familiaris) |
Mammalia | KIAA1522 33 |
|
||
mouse (Mus musculus) |
Mammalia | C77080 33 16 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | RGD1561149 33 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | KIAA1522 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | KIAA1522 34 |
|
OneToOne | |
lizard (Anolis carolinensis) |
Reptilia | KIAA1522 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | kiaa1522 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | si:ch211-194e15.5 34 |
|
OneToMany | |
si:dkey-157l19.2 34 |
|
OneToMany |
- Species where no ortholog for KIAA1522 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for KIAA1522 Gene
No data available for Paralogs for KIAA1522 Gene
Variants for KIAA1522 Gene
SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs536402126 | uncertain-significance, Charcot-Marie-Tooth, Intermediate | 32,775,301(+) | T/C | downstream_transcript_variant | |
rs542816112 | likely-benign, Charcot-Marie-Tooth, Intermediate | 32,775,382(+) | T/G | downstream_transcript_variant | |
rs550239801 | likely-benign, Charcot-Marie-Tooth, Intermediate | 32,775,442(+) | T/C | downstream_transcript_variant | |
rs78319035 | likely-benign, Charcot-Marie-Tooth, Intermediate | 32,775,300(+) | A/C | downstream_transcript_variant | |
rs950577466 | uncertain-significance, Charcot-Marie-Tooth, Intermediate | 32,775,257(+) | A/G | downstream_transcript_variant |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv2657788 | CNV | deletion | 23128226 |
esv2664118 | CNV | deletion | 23128226 |
esv2746552 | CNV | deletion | 23290073 |
esv2746563 | CNV | deletion | 23290073 |
esv3585676 | CNV | loss | 21293372 |
nsv1075410 | CNV | deletion | 25765185 |
nsv1143445 | CNV | deletion | 24896259 |
nsv322 | CNV | deletion | 18451855 |
nsv509158 | CNV | insertion | 20534489 |
nsv519188 | CNV | loss | 19592680 |
Residual Variation Intolerance Score:
47.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.05;
80.27% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for KIAA1522 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- KIAA1522
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for KIAA1522 Gene
Disorders for KIAA1522 Gene
Additional Disease Information for KIAA1522
No disorders were found for KIAA1522 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for KIAA1522 Gene
Publications for KIAA1522 Gene
- Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10819331) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2000) 2 3 4 58
- KIAA1522 is a novel prognostic biomarker in patients with non-small cell lung cancer. (PMID: 27098511) Liu YZ … Wang MR (Scientific reports 2016) 2 3 58
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
- A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58
Products for KIAA1522 Gene
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- Invitrogen Antibodies for KIAA1522
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for KIAA1522
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for KIAA1522
- Search GeneTex for Proteins for KIAA1522
- ViGene Biosciences adenoviral particle packaged cDNA for KIAA1522 gene
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- genomics-online: cdna clones - Search results for available KIAA1522 gene related products
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Sources for KIAA1522 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew