KIAA1407 Gene
protein-coding GIFtS : 40
GCID: GC03 M113682 (predicted)
KIAA1407
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Aliasesfor KIAA1407 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases KIAA1407 1 2 Coiled-Coil Domain-Containing Protein KIAA14072
Export aliases for KIAA1407 gene to outside databases Previous GC identifers: GC03M110504 GC03M113253 GC03M114964 GC03M115003 GC03M115165 GC03M111057
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Summariesfor KIAA1407 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor KIAA1407 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000003.11 NC_018914.1 NT_005612.16 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the KIAA1407 gene promoter: Tal-1 POU6F1 (c2) Ik-3 E47 NF-AT NF-AT4 NF-AT2 NF-AT3 NF-AT1 Other transcription factors Search SABiosciences Chromatin IP Primers for KIAA1407 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat KIAA1407
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 3q13.31 Ensembl cytogenetic band: 3q13.31 HGNC cytogenetic band: 3q13.31 KIAA1407 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 3 GeneLoc Exon Structure
GeneLoc location for GC03M113682: view genomic region
(about GC identifiers )
Start:
113,682,984 bp from pter
End:
113,775,460 bp from pter
Size:
92,477 bases
Orientation:
minus strand
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Proteinsfor KIAA1407 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: K1407_HUMAN, Q8NCU4 (See
protein sequence )Recommended Name: Coiled-coil domain-containing protein KIAA1407 Size : 936 amino acids; 110568 Da
Secondary accessions : Q9P2E0Explore the universe of human proteins at neXtProt for KIAA1407: NX_Q8NCU4 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q8NCU4 KIAA1407 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_065868.1 ENSEMBL proteins: ENSP00000295878 ENSP00000418382 ENSP00000418099 ENSP00000418991 ENSP00000419159 ENSP00000446381 Human Recombinant Protein Products: KIAA1407 Antibody Products: Assay Products for KIAA1407:
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Protein
Domains / Familiesfor KIAA1407 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
KIAA1407 for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q8NCU4 ProtoNet protein and cluster: Q8NCU4
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Functionfor KIAA1407 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for KIAA1407 (see all 2 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for KIAA1407OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: KIAA1407 (NM_020817 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1407 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat KIAA1407
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1407
3 GenomeRNAi human phenotypes for KIAA1407 :
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Pathways & Interactionsfor KIAA1407 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for KIAA1407 STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)1 Interacting protein for KIAA1407 (Q8NCU4 3 ENSP00000295878 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table
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Drugs & Compoundsfor KIAA1407 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for KIAA1407 Search CenterWatch for drugs/clinical trials and news about KIAA1407 / K1407
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Transcriptsfor KIAA1407 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for KIAA1407 gene: NM_020817.1 Unigene Cluster for KIAA1407:
KIAA1407 Hs.477159 [show with all ESTs ] Unigene Representative Sequence: AF509494 9 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000295878 (uc003eax.3 uc011bip.1 ) ENST00000460813 ENST00000527855 ENST00000481358 (uc011bio.1 ) ENST00000491000 ENST00000483766 ENST00000463695 ENST00000480588 ENST00000545063 (uc011bin.1 ) Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for KIAA1407 (see all 2 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for KIAA1407OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: KIAA1407 (NM_020817 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for KIAA1407 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat KIAA1407
Additional cDNA sequence: AB037828.1 AF509494.1 AK125304.1 AK295855.1 AK302488.1 BC150592.1
7 DOTS entries : DT.312379 DT.408927
DT.120867160 DT.95093833 DT.100022122 DT.40131294 DT.91806999 24/77 AceView cDNA sequences (see all 77 ):
AA743318 BM713081 AA953707 AW614521 BM353150 AI056457 AK125304 AA435645 AI985341 BX436915 CA314296 AW193515 BI829144 NM_020817 AF509494 AI950183 AI689804 AI979103 AA398917 AA400761 AB037828 BQ025654 BQ003654 BM312571 GeneLoc Exon Structure
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Expression for KIAA1407 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section KIAA1407 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: CTCCCACCTG
About this image KIAA1407 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table Stem Cell Differentiation: 1 LifeMap Cell Name Category Posterior foregut-like cells (A scalable, suspensi... )Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See KIAA1407 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for KIAA1407 SOURCE GeneReport for Unigene cluster: Hs.477159 SABiosciences Custom PCR Arrays for KIAA1407 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for KIAA1407Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat KIAA1407 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat KIAA1407 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat KIAA1407 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1407
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Orthologsfor KIAA1407 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for KIAA1407 gene from 5/16 species (see all 16 ) About this table
ENSEMBL Gene Tree for KIAA1407 (if available)TreeFam Gene Tree for KIAA1407 (if available)
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Paralogsfor KIAA1407 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor KIAA1407 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 3 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for KIAA1407 (113682984 - 113775460 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for KIAA1407: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing KIAA1407
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Disorders
/ Diseasesfor KIAA1407 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
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Publicationsfor KIAA1407 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for KIAA1407 gene integrated from 9 sources : (articles sorted by number of sources associating them with KIAA1407) Utopia : connect your pdf to the dynamic world of online information
Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198) 1 , 2 , 3 Nagase T.... Ohara O. (2000) Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422) 1 Li S....Dorf M.E. (2011) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id ) 2 Aoki H.... Hino O. (2000)
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External Searches for KIAA1407 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing KIAA1407 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing KIAA1407 gene
(According to HUGE )
About This Section
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Specialized Databases showing KIAA1407 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for KIAA1407 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for KIAA1407 gene: Search GeneIP for patents involving KIAA1407 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor KIAA1407 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for KIAA1407 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for KIAA1407 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for KIAA1407 Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for KIAA1407 OriGene 3'-UTR Clone for KIAA1407 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for KIAA1407 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for KIAA1407 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for KIAA1407 OriGene Custom Protein Services for KIAA1407 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat KIAA1407 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing KIAA1407 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat KIAA1407 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat KIAA1407 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat KIAA1407 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat KIAA1407
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for KIAA1407
Search ThermoFisher Antibodies for KIAA1407
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat KIAA1407
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